Leiomyosarcoma of the skin: review of the literature with an emphasis on prognosis and management.


:Leiomyosarcoma (LMS) of the skin is rare, and no management guideline currently exists. Although LMS is historically classified as either dermal (cutaneous) or subcutaneous, definition for its classfication is inconsistent in the literature. Studies on the managenent of LMS are scarce, and there is no consensus on the appropriate surgical margin for the treatment of LMS. While a 1 cm margin may be sufficient in cutaneous LMS, wider margins may be required for subcutaneous tumors. Mohs micrographic surgery is a promising surgical modality for the treatment of cutaneous LMS. In this review, current knowledge on LMS is summarized and a practical approach to the management of this rare neoplasm is proposed.


Int J Dermatol


Kazlouskaya V,Lai YC,Khachemoune A




Has Abstract


2020-02-01 00:00:00












  • What lichen planus patients die of. A retrospective study.

    abstract::The causes of death of 50 patients who had had lichen planus have been investigated and compared with those of 50 patients with psoriasis and with those of the general population. Patients with lichen planus were as old as those with psoriasis and in the general population at the time of death, but the diseases causin...

    journal_title:International journal of dermatology

    pub_type: 杂志文章


    authors: Anonide A,Rebora A

    更新日期:1989-10-01 00:00:00

  • The genetics of vitiligo in Korean patients.

    abstract:BACKGROUND:Vitiligo is a common disorder whose exact cause is unknown, but genetic factors are thought to be involved. We analyzed 120 Korean proband families to clarify which genetic factors are involved in the pathogenesis of vitiligo in Korean patients. METHODS:The genetics of vitiligo were analyzed in 120 Korean p...

    journal_title:International journal of dermatology

    pub_type: 杂志文章


    authors: Kim SM,Chung HS,Hann SK

    更新日期:1998-12-01 00:00:00

  • The profile of fogo selvagem (endemic pemphigus foliaceus) at the University Hospital of Brasilia-Brazil. Epidemiological and clinical considerations.

    abstract:BACKGROUND:Endemic pemphigus foliaceus (EPF) or fogo selvagem (FS) is an endemic autoimmune disease, characterized by flaccid bullae induced by IgG(4) subclass antibodies. The authors demonstrate the epidemiological and clinical status of patients who have been followed at the University Hospital of Brasilia (HUB) for ...

    journal_title:International journal of dermatology

    pub_type: 杂志文章


    authors: Ribeiro AM,Alvarez RR,Friedman H,Campbell I,Cooperative Group osn Fogo Selvagem Research.

    更新日期:2005-04-01 00:00:00

  • Prevalence of skin diseases in Iraq: a community based study.

    abstract::We sought to determine the prevalence of skin diseases in Iraq. Most such studies performed in Iraq have been hospital based. One community based study was performed in the southern area of Iraq but involved only an urban population. Our study was carried out in two Iraqi governorates, Tikrit and Kirkuk, and involved ...

    journal_title:International journal of dermatology

    pub_type: 杂志文章


    authors: Al Samarai AG

    更新日期:2009-07-01 00:00:00

  • Clinical and psychological characteristics of patients with psoriasis reporting various frequencies of pruritus.

    abstract:BACKGROUND:Pruritus is a common subjective symptom of psoriasis whose levels may be affected by a range of variables. The objective of this study was to evaluate the frequency of pruritus and its associations with clinical and psychological characteristics of psoriasis patients. MATERIALS AND METHODS:One-hundred and s...

    journal_title:International journal of dermatology

    pub_type: 杂志文章


    authors: Janowski K,Steuden S,Bogaczewicz J

    更新日期:2014-07-01 00:00:00

  • Are tattoos associated with negative health-related outcomes and risky behaviors?

    abstract:BACKGROUND:Tattoos have reached broadening mainstream acceptance. Medical professional societies have noted that tattoos may co-occur with high risk behaviors. METHODS:Using a variety of statistical models applied to a sample of 2,008 adults residing in the United States via Amazon's Mechanical Turk, we estimate the a...

    journal_title:International journal of dermatology

    pub_type: 杂志文章


    authors: Mortensen K,French MT,Timming AR

    更新日期:2019-07-01 00:00:00

  • A prospective randomized controlled trial assessing the efficacy of adjunctive hyperbaric oxygen therapy in the treatment of hidradenitis suppurativa.

    abstract::Hyperbaric oxygen therapy (HBOT) appears to enhance wound healing, increase bactericidal activity, and act synergistically with a number of antibiotics. The aim of this study was to evaluate the efficacy of HBOT as an adjunctive therapy in patients with hidradenitis suppurativa (HS) treated with a combination of syste...

    journal_title:International journal of dermatology

    pub_type: 杂志文章,随机对照试验


    authors: Yildiz H,Senol L,Ercan E,Bilgili ME,Karabudak Abuaf O

    更新日期:2016-02-01 00:00:00

  • Gender-specific risk factors for androgenetic alopecia in the Korean general population: Associations with medical comorbidities and general health behaviors.

    abstract:BACKGROUND:The relationships between androgenetic alopecia (AGA) and various factors related to metabolic syndrome have been demonstrated in previous studies. However, it remains unclear because of inconsistent results. We investigated the associations between AGA and various risk factors related to metabolic syndrome ...

    journal_title:International journal of dermatology

    pub_type: 杂志文章


    authors: Kim BK,Choe SJ,Chung HC,Oh SS,Lee WS

    更新日期:2018-02-01 00:00:00

  • Netherton syndrome: a case report and review of the literature.

    abstract::Netherton syndrome is a rare disorder inherited in an autosomal recessive pattern consisting of ichthyosiform dermatosis, hair shaft abnormalities (trichorrhexis invaginata), and an atopic diathesis. Patients with Netherton syndrome have been found to have a mutation on chromosome 5q32 in a gene named SPINK5 (serine p...

    journal_title:International journal of dermatology

    pub_type: 杂志文章,评审


    authors: Sun JD,Linden KG

    更新日期:2006-06-01 00:00:00

  • Infection versus disease in South American blastomycosis.

    abstract::The mechanism of infection in South American blastomycosis is discussed, and the probability of a mild or asymptomatic form of the disease, regressing spontaneously with subsequent immunity, in persons living in endemic areas. Primary lesions in the oral mucosa or in the skin have not been convincingly shown to occur ...

    journal_title:International journal of dermatology

    pub_type: 杂志文章,评审


    authors: Furtado T

    更新日期:1975-03-01 00:00:00

  • A comparison of anti-desmoglein antibodies and indirect immunofluorescence in the serodiagnosis of pemphigus vulgaris.

    abstract:BACKGROUND:Indirect immunofluorescence (IIF) is the standard method for the detection of pemphigus autoantibodies. Commercially available enzyme-linked immunosorbent assays (ELISAs) have recently become available to measure serum antibodies (Abs) against desmoglein1 (Dsg1) and desmoglein3 (Dsg3). It has been suggested ...

    journal_title:International journal of dermatology

    pub_type: 杂志文章


    authors: Zagorodniuk I,Weltfriend S,Shtruminger L,Sprecher E,Kogan O,Pollack S,Bergman R

    更新日期:2005-07-01 00:00:00

  • A randomized, controlled and blinded study of papulopustular lesions in Turkish Behçet's patients.

    abstract:BACKGROUND:Papulopustular lesions (PPL), the commonest presentation of skin lesions in Behcet's disease (BD) are cutaneous, sterile folliculitis or acne-like lesions on erythematous base. Our purpose was to determine the true frequency and anatomic location of the PPL and compare this with controls. We also sought to d...

    journal_title:International journal of dermatology

    pub_type: 杂志文章


    authors: Alpsoy E,Aktekin M,Er H,Durusoy C,Yilmaz E

    更新日期:1998-11-01 00:00:00

  • Paraneoplastic pyoderma gangrenosum in solid organ malignancy: a literature review.

    abstract::Pyoderma gangrenosum (PG) is a rare destructive, ulcerative, and inflammatory cutaneous disease. PG can be associated with inflammatory bowel disease (IBD), arthritis, autoinflammatory syndromes, and hematological malignancies. Multiple reports in the literature have found an association between PG and solid organ tum...

    journal_title:International journal of dermatology

    pub_type: 杂志文章,评审


    authors: Shah M,Sachdeva M,Gefri A,Jfri A

    更新日期:2020-02-01 00:00:00

  • Aquatic dermatology: encounters with the denizens of the deep (and not so deep) a review. Part I: the invertebrates.

    abstract::Aquatic dermatoses encompass a broad spectrum of cutaneous injuries. These injuries may present through contact with invertebrate organisms such as jellyfish, sea urchins, corals, and molluscs. Each organism is equipped with a unique method of causing harm to man, therefore a myriad of presenting signs and symptoms sh...

    journal_title:International journal of dermatology

    pub_type: 杂志文章,评审


    authors: Ottuso P

    更新日期:2013-02-01 00:00:00

  • Nine cases of Japan spotted fever diagnosed at our hospital in 2008.

    abstract:BACKGROUND:The diagnosis of Japan spotted fever (JSF) is very difficult in some cases. The initial diagnosis of JSF is very important to treat. METHODS:We report nine cases of Japan spotted fever (JSF) with variable clinical features diagnosed at our hospital in 2008. RESULTS:Concerning clinical symptom, the most fre...

    journal_title:International journal of dermatology

    pub_type: 杂志文章


    authors: Kondo M,Nishii M,Gabazza EC,Kurokawa I,Akachi S

    更新日期:2010-04-01 00:00:00

  • Multiple cutaneous lymphoproliferative disorders showing a retained tumor clone by T-cell receptor gene rearrangement analysis: a case series of four patients and review of the literature.

    abstract:BACKGROUND:Mycosis fungoides (MF) is the most common primary cutaneous T-cell lymphoma (CTCL), followed by CD30+ lymphoproliferative disorders, including lymphomatoid papulosis (LyP) and primary cutaneous anaplastic large cell lymphoma (pcALCL). The objective was to report on a series of patients with different types o...

    journal_title:International journal of dermatology

    pub_type: 杂志文章,评审


    authors: Stowman AM,Hsia LL,Kanner WA,Mahadevan MS,Bullock GC,Patterson JW

    更新日期:2016-02-01 00:00:00

  • Lymphoid proliferation and lymphoma associated with human retroviruses (HTLV and HIV).

    abstract::There are rapidly increasing opportunities for dermatologists to see patients suffering from retrovirus infections. The HTLV-I was the first class of human oncogenic retrovirus that was found in cultured cells of a patient with skin manifestations similar or identical to those of CTCL (MF). It was soon recognized as t...

    journal_title:International journal of dermatology

    pub_type: 杂志文章,评审


    authors: Jimbow K,Jewell LD

    更新日期:1991-09-01 00:00:00

  • The "collerette" technique for skin excision and biopsy: an efficient method for managing lentigo maligna of the head and neck.

    abstract:BACKGROUND:Melanoma is responsible for 75% of all skin cancer-related deaths. Lentigo maligna (LM), the most prevalent melanoma in situ (MIS), accounts for 79-83% of all MIS. Its location in the head and neck area requires that tissue be spared in the course of clearing the tumor. METHODS:We conducted a therapeutic st...

    journal_title:International journal of dermatology

    pub_type: 杂志文章


    authors: Kassi K,Vanwijck R,Kanga JM

    更新日期:2014-07-01 00:00:00

  • CD8+ cytotoxic mycosis fungoides: a retrospective analysis of clinical features and follow-up results of 29 patients.

    abstract:BACKGROUND AND OBJECTIVE:Less than 5% of cases of mycosis fungoides (MF) present with a cytotoxic/suppressor CD8+ phenotype. This study aimed to evaluate the clinical characteristics, treatment modalities, and clinical course in CD8+ MF patients. METHODS:In a retrospective analysis of 353 MF patients in a referral cen...

    journal_title:International journal of dermatology

    pub_type: 杂志文章


    authors: Kalay Yildizhan I,Sanli H,Akay BN,Sürgün E,Heper A

    更新日期:2020-01-01 00:00:00

  • Hidradenitis suppurativa is associated with hypothyroidism and hyperthyroidism: a large-scale population-based study.

    abstract:BACKGROUND:Hidradenitis suppurativa (HS) is a chronic inflammatory disease involving the skin bearing apocrine glands. There are numerous comorbidities and associated diseases among patients with HS. The association of HS and thyroid abnormalities is equivocal. We aimed to explore whether HS is associated with thyroid ...

    journal_title:International journal of dermatology

    pub_type: 杂志文章


    authors: Sherman S,Tzur Bitan D,Kridin K,Pavlovsky L,Hodak E,Cohen AD

    更新日期:2020-11-25 00:00:00

  • Onychomycosis in Hong Kong.

    abstract:BACKGROUND:Onychomycosis in temperate countries has been studied extensively, but few data are available on its epidemiology in tropical countries. We performed a survey of patients seen in Hong Kong for the 8-year period from January 1987 to December 1994. METHODS:A retrospective study of the mycology laboratory reco...

    journal_title:International journal of dermatology

    pub_type: 杂志文章


    authors: Kam KM,Au WF,Wong PY,Cheung MM

    更新日期:1997-10-01 00:00:00

  • Lichen planus pigmentosus inversus: a series of 10 Tunisian patients.

    abstract:BACKGROUND:Lichen planus pigmentosus inversus (LPPI) is a rare variant of LP. Only 31 cases have been reported in the literature. METHODS:Here we report a series of 10 patients with LPPI from North Africa. RESULTS:Ten cases of LPPI, clinically suspected and histologically confirmed, were seen over 3 years (2013-2015)...

    journal_title:International journal of dermatology

    pub_type: 杂志文章


    authors: Mohamed M,Korbi M,Hammedi F,Youssef M,Soua Y,Akkari H,Lahouel I,Belhadjali H,Zili J

    更新日期:2016-10-01 00:00:00

  • Dermatologic infestations.

    abstract::Head lice are transmitted by head to head contact. Optimal therapy includes malathion lotion 0.5% repeated in one week left on for 30 minutes to 8 hours. Spinosad topical suspension 0.9% repeated in one week left on for 10 minutes is another option. Scabies is transmitted mainly by direct contact but also via heavily ...

    journal_title:International journal of dermatology

    pub_type: 杂志文章,评审


    authors: Shmidt E,Levitt J

    更新日期:2012-02-01 00:00:00

  • Pneumocystis jiroveci pneumonia in patients treated with systemic immunosuppressive agents for dermatologic conditions: a systematic review with recommendations for prophylaxis.

    abstract::Pneumocystis jiroveci pneumonia is an opportunistic infection associated with substantial rates of mortality in immunosuppressed patients. Prophylaxis recommendations are mostly targeted toward patients with non-dermatologic diagnoses. This study was conducted to determine when dermatology patients treated with immuno...

    journal_title:International journal of dermatology

    pub_type: 杂志文章,评审


    authors: Gonzalez Santiago TM,Wetter DA,Kalaaji AN,Limper AH,Lehman JS

    更新日期:2016-08-01 00:00:00

  • Iron, copper, and zinc concentrations in normal skin and in various nonmalignant and malignant lesions.

    abstract::The concentrations of zinc (Zn), copper (Cu), and iron (Fe) in the skin have been noninvasively determined in vivo by diagnostic x-ray spectrometry. The skin of healthy controls was divided into two major groups based upon the distribution of the concentrations of these elements. In the face and upper neck, the follow...

    journal_title:International journal of dermatology

    pub_type: 杂志文章


    authors: Gorodetsky R,Sheskin J,Weinreb A

    更新日期:1986-09-01 00:00:00

  • Cytodiagnosis of cutaneous basal and squamous cell carcinoma.

    abstract:OBJECTIVE:We performed a prospective study to evaluate the diagnostic accuracy of cytologic examination in basal cell carcinomas (BCCs) and squamous cell carcinomas (SCCs), in order to assess its clinical value. Study design Samples were taken by the "scraping" technique which involves scraping with a scalpel blade dir...

    journal_title:International journal of dermatology

    pub_type: 杂志文章


    authors: Vega-Memije E,De Larios NM,Waxtein LM,Dominguez-Soto L

    更新日期:2000-02-01 00:00:00

  • Is pemphigus herpetiformis an entity?

    abstract::Clinical, histologic, and immunofluorescence studies were performed in 15 patients with pemphigus herpetiformis. The initial diagnosis was dermatitis herpetiformis, IgA linear bullous dermatosis or bullous pemphigoid. The histology varied depending on the character of skin lesions, and showed eosinophilic spongiosis o...

    journal_title:International journal of dermatology

    pub_type: 杂志文章


    authors: Maciejowska E,Jablonska S,Chorzelski T

    更新日期:1987-11-01 00:00:00

  • Misconceptions about laser treatment among dermatology patients.

    abstract:BACKGROUND:The use of lasers is very common in dermatology; however, many patients fear it and have various misconceptions about it. A literature search failed to show any studies on this topic. OBJECTIVE:To explore the various misconceptions of patients about lasers in dermatology. METHODS:A self-administered questi...

    journal_title:International journal of dermatology

    pub_type: 杂志文章


    authors: AlGhamdi KM,Moussa NA

    更新日期:2011-11-01 00:00:00

  • Multiple agminated pigmented Spitz nevi (mimicking acral lentiginous malignant melanoma and dysplastic nevus) in an African-American girl.

    abstract:BACKGROUND:Reed's nevi are distinguished from Sptiz tumors by their significant melanogenesis and growth pattern. They may be confused with melanoma on clinical and histologic grounds. CASE REPORT:An unusual case in which multiple agminated Reed's nevi mimicked acral lentiginous malignant melanoma in an African-Americ...

    journal_title:International journal of dermatology

    pub_type: 杂志文章


    authors: Abramovits W,Gonzalez-Serva A

    更新日期:1993-04-01 00:00:00

  • Keratosis lichenoides chronica in an Indian child following erythroderma.

    abstract::A 4-year-old boy presented with mildly itchy, linear, skin lesions over the trunk, arms, and face of 3 months' duration. He had previously been admitted to a private hospital for generalized exfoliation of the skin following drug intake for fever and throat pain. The nature of the drugs was not known. The exfoliative ...

    journal_title:International journal of dermatology

    pub_type: 杂志文章


    authors: Ghorpade A

    更新日期:2008-09-01 00:00:00