Abstract：
BACKGROUND:Melanoma is responsible for 75% of all skin cancer-related deaths. Lentigo maligna (LM), the most prevalent melanoma in situ (MIS), accounts for 79-83% of all MIS. Its location in the head and neck area requires that tissue be spared in the course of clearing the tumor. METHODS:We conducted a therapeutic study based on our practice experience with the so-called "collarette" skin biopsy technique used in the management of LM. RESULTS:Thirty-one patients were diagnosed with LM in the head and neck area. These included 16 women and 15 men with a mean ± standard deviation (SD) age of 64.4 ± 13.6 years (range: 33-88 years). The majority (36%) of lesions were located on the cheek. To clear the tumor, surgery was performed using margins of >10 mm in 71% of cases. The average surface area of the surgical defect was 5.8 cm(2) (range: 1.1-15.5 cm(2) ). Reconstructive skin grafts were performed in the majority (68%) of cases. After the removal of the central tumor, 16 cases of MIS and 15 cases of invasive melanoma were identified. Only one patient experienced recurrence over a mean ± SD follow-up of 31 ± 16 months. CONCLUSIONS:The so-called "collarette" or "spaghetti" skin excision and biopsy technique is an advantageous and efficient way to achieve tumor clearance and represents an equally effective alternative to Mohs micrographic surgery in the treatment of LM in the head and neck area.
journal_name
Int J Dermatoljournal_title
International journal of dermatologyauthors
Kassi K,Vanwijck R,Kanga JMdoi
10.1111/ijd.12430subject
Has Abstractpub_date
2014-07-01 00:00:00pages
899-903issue
7eissn
0011-9059issn
1365-4632journal_volume
53pub_type
杂志文章abstract：BACKGROUND:Histoid leprosy is a rare form of multibacillary leprosy as the result of secondary or even primary resistance to dapsone. The etiopathogenesis has not been clarified up to now. METHODS:An immunohistochemical study was carried out for the expression of various markers on epidermal and dermal cell population...
journal_title：International journal of dermatology
pub_type： 杂志文章
doi：10.1111/j.1365-4362.1995.tb04396.x
更新日期：1995-11-01 00:00:00
abstract：BACKGROUND:Melanocytic nevi are well-known, important precursors of melanoma among children and adults. The adolescence period is an important period for nevi formation and evolution. This study provides data of a longitudinal study of nevi in a Hispanic adolescent population. MATERIALS AND METHODS:A cross-sectional s...
journal_title：International journal of dermatology
pub_type： 杂志文章
doi：10.1111/j.1365-4632.2012.5784.x
更新日期：2014-03-01 00:00:00
abstract：OBJECTIVES:The purpose of this study is to review the published articles regarding different surgical modalities including laser therapy in the treatment of congenital melanocytic nevi (CMN). METHODS:A systematic review was done using several databases including PubMed, Ovid Medline, Google Scholar, and Medline to sea...
journal_title：International journal of dermatology
pub_type： 杂志文章
doi：10.1111/ijd.14727
更新日期：2020-05-01 00:00:00
abstract：:Psoriasis is a chronic inflammatory skin disorder which can impair general routine activities and has been closely related to poor quality of life. Pruritus and scratching are frequently observed, occurring mainly during sleep and precipitating nighttime arousals. Indeed, sleep quality has been shown to be negatively ...
journal_title：International journal of dermatology
pub_type： 杂志文章,评审
doi：10.1111/ijd.13026
更新日期：2015-12-01 00:00:00
abstract：BACKGROUND:Antitumor necrosis factor (anti-TNF) agents are a well-established treatment for various medical conditions, including psoriasis and psoriatic arthritis. However, anti-TNF agents may themselves induce psoriasis in some patients. METHODS:The authors report two cases of patients with severe and refractory inf...
journal_title：International journal of dermatology
pub_type： 杂志文章
doi：10.1111/j.1365-4632.2012.05601.x
更新日期：2013-02-01 00:00:00
abstract：:Clinical, histologic, and immunofluorescence studies were performed in 15 patients with pemphigus herpetiformis. The initial diagnosis was dermatitis herpetiformis, IgA linear bullous dermatosis or bullous pemphigoid. The histology varied depending on the character of skin lesions, and showed eosinophilic spongiosis o...
journal_title：International journal of dermatology
pub_type： 杂志文章
doi：10.1111/j.1365-4362.1987.tb02308.x
更新日期：1987-11-01 00:00:00
abstract：BACKGROUND:Vitiligo is a hypopigmentation disease characterized by achromatic or hypochromatic macules in several sites of human skin. Although monochromatic excimer light (MEL) and narrowband-ultraviolet B (NB-UVB) have recently been used for efficacious treatment of vitiligo, the repigmentation process and role of me...
journal_title：International journal of dermatology
pub_type： 杂志文章
doi：10.1111/ijd.14216
更新日期：2019-02-01 00:00:00
abstract：:A double-blind study of 30 patients with mild to moderate acne vulgaris was conducted to evaluate the efficacy of a topically applied 2% zinc sulfate solution for acne therapy. Over a 12-week period, no difference was noted between placebo- and zinc-treated participants in regard to either the number or type of acne l...
journal_title：International journal of dermatology
pub_type： 临床试验,杂志文章
doi：10.1111/j.1365-4362.1985.tb05756.x
更新日期：1985-04-01 00:00:00
abstract：:There are rapidly increasing opportunities for dermatologists to see patients suffering from retrovirus infections. The HTLV-I was the first class of human oncogenic retrovirus that was found in cultured cells of a patient with skin manifestations similar or identical to those of CTCL (MF). It was soon recognized as t...
journal_title：International journal of dermatology
pub_type： 杂志文章,评审
doi：10.1111/j.1365-4362.1991.tb03483.x
更新日期：1991-09-01 00:00:00
abstract：BACKGROUND:Potent teratogenicity limits the use of isotretinoin among females of childbearing potential (FCBP). OBJECTIVE:To explore the current practice of dermatologists for pregnancy prevention when prescribing isotretinoin for FCBP. MATERIALS AND METHODS:A self-administered questionnaire was distributed to 160 de...
journal_title：International journal of dermatology
pub_type： 杂志文章
doi：10.1111/j.1365-4632.2011.04875.x
更新日期：2011-09-01 00:00:00
abstract：BACKGROUND:Although disease severity, gender, body weight, and previous treatments have all been reported to affect clinical response of psoriasis vulgaris to narrowband ultraviolet B (NB-UVB) therapy, little information about possible local (lesional) influencing factors is available. OBJECTIVE:To assess correlations...
journal_title：International journal of dermatology
pub_type： 杂志文章
doi：10.1111/ijd.13983
更新日期：2018-06-01 00:00:00
abstract：BACKGROUND:Health-related quality of life instruments are typically developed and validated for use in developed countries by patients who can read and write. Little is known about the feasibility of using adaptations of validated instruments in situations where literacy rates are low. OBJECTIVE:We aimed to translate,...
journal_title：International journal of dermatology
pub_type： 杂志文章
doi：10.1111/j.1365-4632.2011.04894.x
更新日期：2011-10-01 00:00:00
abstract：:In order to deliver equal healthcare access to resource-poor settings, sustainable, cost-effective systems of communication should be used. As mobile phone use increases, remote care can be delivered via teledermatology using Apps. This commentary covers how WhatsApp could be used by dermatologists seeking to deliver ...
journal_title：International journal of dermatology
pub_type： 杂志文章
doi：10.1111/ijd.14237
更新日期：2019-02-01 00:00:00
abstract：OBJECTIVE:To assess the efficacy and safety of topical 5% cysteamine versus 4% hydroquinone in the treatment of facial melasma in women. Topical 5% cysteamine is an antioxidant and tyrosinase inhibitor that has been shown to be effective in the treatment of melasma. However, to date, no study has compared the performan...
journal_title：International journal of dermatology
pub_type： 杂志文章
doi：10.1111/ijd.15146
更新日期：2020-12-01 00:00:00
abstract：PURPOSE:To investigate the effects of various types of Dead Sea mud (DSM) on skin barrier properties over a period of four weeks. METHODS:The effects of a 4-week application of three types of DSM (as is mud, mud with extra Dead Sea salt, and over the shelf mud) on the barrier properties of normal skin were investigate...
journal_title：International journal of dermatology
pub_type： 杂志文章
doi：10.1111/ijd.15304
更新日期：2020-12-07 00:00:00
abstract：BACKGROUND:CD4+ CD25+ T-regulatory (Treg) cells play critical roles in maintaining peripheral tolerance and preventing autoimmunity. As characteristics of Treg cells have not been precisely investigated in chronic urticaria (CU) yet, this study was performed. OBJECTIVE:To determine the frequencies of circulating CD4+ ...
journal_title：International journal of dermatology
pub_type： 杂志文章
doi：10.1111/ijd.12630
更新日期：2014-12-01 00:00:00
abstract：:An 11-year-old girl who at 9 1/2 months was diagnosed as having keratoderma of the palms and soles, present since birth, developed typical granuloma annulare at the age of 11 years. To the authors' knowledge, this is the first report of epidermolytic palmo-plantar keratoderma associated with granuloma annulare. There ...
journal_title：International journal of dermatology
pub_type： 杂志文章
doi：10.1111/j.1365-4362.1984.tb01225.x
更新日期：1984-12-01 00:00:00
abstract：BACKGROUND:Treatment of wrinkles has become an increasing problem for dermatologists. Hyaluronic acid is a component of the family of glycosaminoglycans (GAGS, substances known for their property of retaining water), that significantly decreases with aging and in wrinkles. A new technique that uses a specific pulsed el...
journal_title：International journal of dermatology
pub_type： 杂志文章
doi：10.1111/j.1365-4362.1994.tb02933.x
更新日期：1994-09-01 00:00:00
abstract：:Punch grafting is an established treatment modality for management of localized, nonprogressive vitiligo resistant to conventional therapies.(1) In our set up, punch grafting is routinely carried out in focal vitiligo, segmental vitiligo and even in few cases of generalized vitiligo, especially when it is a serious co...
journal_title：International journal of dermatology
pub_type： 杂志文章
doi：10.1111/j.1365-4632.2004.01889.x
更新日期：2004-04-01 00:00:00
abstract：BACKGROUND:In vitiligo, other than loss of melanocytes and melanin pigment in the lesional skin, keratinocytes are also involved. Human fetal Merkel cells are now generally considered to be derived from the epidermis. To date, no observations on Merkel cells in lesional skin of active vitiligo have been reported. METH...
journal_title：International journal of dermatology
pub_type： 杂志文章
doi：10.1111/j.1365-4362.1994.tb02859.x
更新日期：1994-07-01 00:00:00
abstract：BACKGROUND:Vitiligo is a common disorder whose exact cause is unknown, but genetic factors are thought to be involved. We analyzed 120 Korean proband families to clarify which genetic factors are involved in the pathogenesis of vitiligo in Korean patients. METHODS:The genetics of vitiligo were analyzed in 120 Korean p...
journal_title：International journal of dermatology
pub_type： 杂志文章
doi：10.1046/j.1365-4362.1998.00549.x
更新日期：1998-12-01 00:00:00
abstract：BACKGROUND:Vitamin C has been used for the treatment of hyperpigmented diseases. However, there is no study available on hypopigmenting effect of multivitamin. OBJECTIVES:To investigate the inhibitory effects of multivitamin and vitamin C on melanogenesis. METHODS:We assessed the effect of multivitamin and vitamin C ...
journal_title：International journal of dermatology
pub_type： 杂志文章,随机对照试验
doi：10.1111/j.1365-4632.2009.04336.x
更新日期：2010-02-01 00:00:00
abstract：BACKGROUND:Clindamycin phosphate (CLDMP) is effective against Gram-positive and anaerobic bacteria, and is known to have anti-inflammatory properties. METHODS:To further study the anti-inflammatory properties of CLDMP, we examined the scavenging effects on superoxide anion and hydroxyl radical using an electron spin r...
journal_title：International journal of dermatology
pub_type： 杂志文章
doi：10.1111/j.1365-4632.2007.03338.x
更新日期：2007-11-01 00:00:00
abstract：:During a 10-year period (1976-1985), eight Chinese patients from a population of 2.5 million fulfilled the criteria for dermatitis herpetiformis and linear IgA bullous dermatosis (LABD). These rare diseases among Asians presented during the third decade of life with homogenous linear IgA deposits along the dermoepider...
journal_title：International journal of dermatology
pub_type： 杂志文章
doi：10.1111/j.1365-4362.1988.tb02328.x
更新日期：1988-01-01 00:00:00
abstract：:A 31-year-old Caucasian male presented with a history of erythematous, saccular outpouchings of the skin on his back, shoulders, and upper extremities (Fig. 1). The patient reported that his mother and aunt had a similar skin disorder, which initially began with inflammation, but healed leaving lax skin in its wake. H...
journal_title：International journal of dermatology
pub_type： 杂志文章
doi：10.1046/j.1365-4362.2003.01742.x
更新日期：2003-01-01 00:00:00
abstract：:Idiopathic palmar and plantar hyperhidrosis is a relatively common disorder of eccrine sweat gland function. Treatment with glutaraldehyde of formaldehyde, although successful, may cause undesirable side effects. Methenamine is a polycyclic organic compound which release ammonia and formaldehyde at acid pH. Five per c...
journal_title：International journal of dermatology
pub_type： 临床试验,杂志文章
doi：10.1111/j.1365-4362.1976.tb00240.x
更新日期：1976-07-01 00:00:00
abstract：:Necrolytic acral erythema is a relatively recently described psoriasis-like skin eruption seen in people infected with hepatitis C virus. Hepatitis C virus infection is endemic in many parts of the world with a steady increase of incidence in Pakistan. Recognition of this disorder is crucial to an early treatment of t...
journal_title：International journal of dermatology
pub_type： 杂志文章
doi：10.1111/j.1365-4632.2008.03710.x
更新日期：2008-10-01 00:00:00
abstract：:Erosive pustular dermatosis of the scalp is a rare condition which primarily affects older women after local trauma and has historically been treated with topical steroids. As it is a rare entity and resembles other dermatologic conditions, it may easily be misdiagnosed. Identifying the causes and evaluating the effic...
journal_title：International journal of dermatology
pub_type： 杂志文章,评审
doi：10.1111/ijd.14955
更新日期：2021-01-01 00:00:00
abstract：:The topical application of mechlorethamine is associated with a high incidence of irritant contact dermatitis. An attempt was made to avoid this complication by the use of a topical tolerogenic schedule. Seven of ten patients developed contact dermatitis to the medication after they had completed the schedule, The use...
journal_title：International journal of dermatology
pub_type： 杂志文章
doi：10.1111/ijd.1979.18.5.390
更新日期：1979-06-01 00:00:00
abstract：BACKGROUND:Lichen planus pigmentosus inversus (LPPI) is a rare variant of LP. Only 31 cases have been reported in the literature. METHODS:Here we report a series of 10 patients with LPPI from North Africa. RESULTS:Ten cases of LPPI, clinically suspected and histologically confirmed, were seen over 3 years (2013-2015)...
journal_title：International journal of dermatology
pub_type： 杂志文章
doi：10.1111/ijd.13295
更新日期：2016-10-01 00:00:00
