Severe infliximab-induced psoriasis treated with adalimumab switching.

Abstract:

BACKGROUND:Antitumor necrosis factor (anti-TNF) agents are a well-established treatment for various medical conditions, including psoriasis and psoriatic arthritis. However, anti-TNF agents may themselves induce psoriasis in some patients. METHODS:The authors report two cases of patients with severe and refractory infliximab-induced psoriasis. RESULTS:The patients had good clinical responses after switching to another TNF blocker. CONCLUSION:For severe cases, infliximab withdrawal combined with conventional immunosuppressive psoriasis drugs or with adalimumab may be a therapeutic option.

journal_name

Int J Dermatol

authors

Faillace C,Duarte GV,Cunha RS,de Carvalho JF

doi

10.1111/j.1365-4632.2012.05601.x

subject

Has Abstract

pub_date

2013-02-01 00:00:00

pages

234-8

issue

2

eissn

0011-9059

issn

1365-4632

journal_volume

52

pub_type

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