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A microtiter cell-culture assay for the determination of anti-human immunodeficiency virus neutralizing antibody activity.

Abstract：

:A microtiter cell-culture assay is described for measuring neutralizing antibody activity directed against the human immunodeficiency virus (HIV). The assay relies upon inhibition of HIV-mediated cell killing of infected MT-4 lymphoid cells. The assay exhibits comparable sensitivity to two other methods used for such measurements, is relatively rapid, may be adapted for screening large numbers of samples and involves minimal handling of infectious virus.

journal_name

J Virol Methods

journal_title

Journal of virological methods

authors

Robertson GA,Kostek BM,Schleif WA,Lewis JA,Emini EA

doi

10.1016/0166-0934(88)90123-1

subject

Has Abstract

pub_date

1988-07-01 00:00:00

pages

195-202

issue

3

eissn

0166-0934

issn

1879-0984

pii

0166-0934(88)90123-1

journal_volume

20

pub_type

杂志文章

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