Abstract:
AIM:To ascertain whether high arterial rigidity is obligatory in arterial hypertension (AH) and the presence of AH is obligatory in patients with rigid arteries. MATERIAL AND METHODS:Volume sphygmography (VS) was made in 153 patients aged 60-86 years: 96 patients with untreated AH of degree 1-3 (40 males aged 71.0 +/- 7.6 years) and 57 normotensive subjects without cardiovascular symptoms (31 males aged 66.6 +/- 6.2 years). VS measured ankle-shoulder velocity of the pulse wave (PWVas) and cardiac-ankle vascular index (CAVI). PWVas > M+STD and CAVI > M+2STD (STD is deviation from mean value) were considered above normal for the age. RESULTS:Hypertensive patients had significantly higher arterial rigidity than normotensives (PWVas 178 +/- 3.0 and 15.6 +/- 2.3 m/s, respectively, p = 0.00001); CAVI--9.7 +/- 2.1 and 8.6 +/- 1.1, respectively, p = 0.0003). Arterial rigidity in hypertensive patients occurred significantly more frequently than in normotensive subjects: by PWVas in 46 and 25% cases (p = 0.01), by CAVI--in 41 and 5% cases (p < 0.0001), respectively. It is essential that arterial rigidity was not increased in 54% hypertensive patients by PWVas and in 75% by CAVI. CONCLUSION:PWVas and CAVI were higher in elderly hypertensives than in elderly normotensives but elevated arterial rigidity was not obligatory in hypertensives while 25% elderly normotensives had it. Thus, elevated arterial rigidity is an essential but not obligatory mechanism of AH development in the elderly.
journal_name
Ter Arkhjournal_title
Terapevticheskii arkhivauthors
Boĭtsov SA,Rogoza AN,Kanishcheva E,Luk'ianov MMsubject
Has Abstractpub_date
2011-01-01 00:00:00pages
5-9issue
9eissn
0040-3660issn
2309-5342journal_volume
83pub_type
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journal_title:Terapevticheskii arkhiv
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