Abstract:
:A study was made of the survival time of erythrocytes labeled with 51Cr in 30 patients with hypoplastic anemia. In 96.7% of the patients erythrocyte survival time was reduced (from 18 to 3.6 days; an average of 11.8 days), an increase in the number of macrocytes was noted (in 83.3%). The mean volume and thickness of erythrocytes were also on an increase (in 95.8%); a decrease in the spherical index of erythrocytes was noted (in 91.6%). In this connection erythrokaryocyte proliferation enhancement was noted in 58.3% of the patients in parallel with a decrease in the total number of myelokaryocytes in 37.5%. The patients' response to multimodality therapy was different irrespective of erythrocyte survival time in the patients with hypoplastic anemia. In satisfactory preservation of medullary hemopoietic foci, particularly with polymorphous cell composition, multimodality therapy including splenectomy, produced mainly a curative effect in patients of different age with hypoplastic anemia.
journal_name
Ter Arkhjournal_title
Terapevticheskii arkhivauthors
Rakhmatullaev AR,Karitskaia GKsubject
Has Abstractpub_date
1987-01-01 00:00:00pages
98-101issue
9eissn
0040-3660issn
2309-5342journal_volume
59pub_type
杂志文章abstract:AIM:To detect specific morphological signs of hepatic lesion in patients with cholesterosis of the gall bladder and atherogenic dyslipidemia in the presence of steatohepatitis. MATERIAL AND METHODS:Atherogenic dyslipidemia was detected in 150 patients with steatohepatitis. Ultrasound investigation diagnosed cholestero...
journal_title:Terapevticheskii arkhiv
pub_type: 杂志文章
doi:
更新日期:2008-01-01 00:00:00
abstract::In three patients with multiple myeloma, stage IIIA, a complete remission lasting from 6 to 8 years was attained, in spite of the fact that not all of them received treatment. In the latter case the remission lasted from 5 to 6 years. One of the patients had diffuse Gk + BIk myeloma, one presented with multiple focal ...
journal_title:Terapevticheskii arkhiv
pub_type: 杂志文章
doi:
更新日期:1985-01-01 00:00:00
abstract:AIM:To clarify the effect of cyclosporin A (CSA) on the apoptosis and proliferative activity of bone marrow cells in patients with aplastic syndromes by trepanobiopsy evidence. MATERIALS AND METHODS:The TUNEL immunohistochemical assay was used to study apoptosis of bone marrow cells in the histological specimens from ...
journal_title:Terapevticheskii arkhiv
pub_type: 杂志文章
doi:
更新日期:2001-01-01 00:00:00
abstract::A rare observation of systemic AL-amyloidosis with a debut in old age, accompanied by diffuse alveolar-septal lesion of the lungs and mediastinal lymphadenopathy in combination with amyloid cardiomyopathy in the absence of pathology of kidney and liver function. ...
journal_title:Terapevticheskii arkhiv
pub_type:
doi:10.26442/00403660.2018.12.000016
更新日期:2018-12-30 00:00:00
abstract::Five HBsAg carriers were examined by clinical, biochemical, radionuclide, immunologic and histomorphologic methods. Different variants of structural and functional relations were established. Attempts were made to eradicate the persistent virus carrierstate with the aid of the antiviral drug virasol, the immunomodulat...
journal_title:Terapevticheskii arkhiv
pub_type: 杂志文章
doi:
更新日期:1984-01-01 00:00:00
abstract::A study was made of exercise tolerance and indices of central hemodynamics in 151 patients with "isolated" angina and its combination with cardialgia, arterial hypertension and postinfarctional cardiosclerosis. Daily attacks of angina of effort (III functional class) were noted in all the patients. In patients with "i...
journal_title:Terapevticheskii arkhiv
pub_type: 临床试验,杂志文章
doi:
更新日期:1986-01-01 00:00:00
abstract:AIM:To study the epidemiology of multiple myeloma in the city of Moscow and compare the results obtained with data from similar studies in other countries. MATERIALS AND METHODS:The study is based on information from a database of case histories of 3942 patients suffering from symptomatic MM, residents of the city of ...
journal_title:Terapevticheskii arkhiv
pub_type: 杂志文章
doi:10.26442/00403660.2019.07.000305
更新日期:2019-07-15 00:00:00
abstract::Altogether 103 patients with rheumatic heart disease were examined within different times after prosthetics of heart valves (mitral or aortal). The purpose was to elaborate the principles of applying the data of instrumental methods of cardiological examination to the improvement of disability criteria. The examinatio...
journal_title:Terapevticheskii arkhiv
pub_type: 杂志文章
doi:
更新日期:1994-01-01 00:00:00
abstract::Low patient compliance due to the development of adverse events in the form of antibiotic-associated diarrhea (AAD) is considered as the main reason for the failure of the eradication of optimized anti-Helicobacter therapy regimens. A key mechanism for the development of AAD is to reduce the number and species diversi...
journal_title:Terapevticheskii arkhiv
pub_type: 杂志文章
doi:10.26442/00403660.2020.04.000647
更新日期:2020-05-19 00:00:00
abstract::A study was made of the nature of secondary immuno-deficiency, peculiarities of disordered function of regulatory T-lymphocytes (helpers and suppressors), and their interrelationships in different clinical variants of chronic glomerulonephritis (CGN). Altogether 94 CGN patients were examined, of them 34 were with urin...
journal_title:Terapevticheskii arkhiv
pub_type: 杂志文章
doi:
更新日期:1987-01-01 00:00:00
abstract::Alcohol consumption practice was studied by a method of interview in an unorganized male population aged 40 to 59 investigated by a program of multifactorial CHD prevention. The frequency of spreading of this habit and its intensity were determined. The frequency of alcohol consumption was decreased with age and was a...
journal_title:Terapevticheskii arkhiv
pub_type: 杂志文章
doi:
更新日期:1988-01-01 00:00:00
abstract:AIM:To assess efficacy of vaccine against viral hepatitis B (VHB) in adults after achievement of acute leukemia (AL) remission. MATERIAL AND METHODS:Specific prevention of VHB was made in 30 AL patients with recombinant vaccine Engerix B by two schemes: 0-1-2-12 and 0-1-2-6 months with double adult dose 40 mcg. Effica...
journal_title:Terapevticheskii arkhiv
pub_type: 杂志文章
doi:
更新日期:2008-01-01 00:00:00
abstract:AIM:To investigate the impact of menopausal hormone therapy (MHT) on the expression of risk factors for cardiovascular events (CVEs) in patients with Shereshevsky-Turner syndrome (STS); to elaborate an algorithm for patient management using MHT. SUBJECTS AND METHODS:From 2010 to 2012, a total of 41 patients aged 14 to...
journal_title:Terapevticheskii arkhiv
pub_type: 杂志文章
doi:10.17116/terarkh2017891048-53
更新日期:2017-01-01 00:00:00
abstract:AIM:To evaluate prevalence of bronchial asthma (BA) and allergic rhinitis (AR) among adult population of St-Petersburg. MATERIAL AND METHODS:Responders to ECRHS and B. Sibbald & E. Rink questionnaires who gave at least one positive answer were examined clinically, functionally and allergologically. A total of 3634 res...
journal_title:Terapevticheskii arkhiv
pub_type: 杂志文章
doi:
更新日期:2003-01-01 00:00:00
abstract::One-stage epidemiological survey permitted one to define the limits of normal blood pressure values in schoolchildren aged 7-17 years for each age-sexual group differentially. Isolated blood pressure elevation was found to be rare, amounting to 4.4% in boys and to 3.1% in girls. The rate of new cases of elevated blood...
journal_title:Terapevticheskii arkhiv
pub_type: 杂志文章
doi:
更新日期:1984-01-01 00:00:00
abstract::Antiarrhythmic efficiency and specific effects of ethmozine, taken alone in increasing oral doses from 300 to 450 mg daily, were evaluated in 48 elderly and old coronary patients with stable supraventricular and ventricular extrasystoles (SVES, VES). It was demonstrated clinically and instrumentally (ECG, rhythmograph...
journal_title:Terapevticheskii arkhiv
pub_type: 杂志文章
doi:
更新日期:1986-01-01 00:00:00
abstract:AIM:To study the survival and sequestration of transfused donor platelets labeled with 51Cr in patients with acute leukemia (AL). SUBJECTS AND METHODS:Seven donor volunteers and 39 patients with different forms with AL at various stages of polychemotherapy (PCT) were examined. Cytostatic therapy was accompanied by 51C...
journal_title:Terapevticheskii arkhiv
pub_type: 杂志文章
doi:
更新日期:2010-01-01 00:00:00
abstract:AIM:To quantify interleukin-8 (IL-8), interleukin-2 (IL-2) and soluble receptor of IL-2 (sIL-2r) in blood serum of patients with various forms of ischemic heart disease (IHD). MATERIAL AND METHODS:Levels of IL-8, IL-2 and sIL-2r were measured with enzyme immunoassay (EIA) in the serum of 75 patients with IHD: angina o...
journal_title:Terapevticheskii arkhiv
pub_type: 杂志文章
doi:
更新日期:2001-01-01 00:00:00
abstract:AIM:To investigate effects of trimetazidine and perindopril on myocardial function and metabolism in patients with cardiac failure after myocardial infarction. MATERIAL AND METHODS:A comparative study was mode of the effects of 6-month therapy with perindopril, trimetazidine alone and in combination on clinical sympto...
journal_title:Terapevticheskii arkhiv
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:2003-01-01 00:00:00
abstract:AIM:The article presents data on the evaluation of the clinical efficacy of using a conjugated pneumococcal vaccine in patients with COPD in combination with 2-type diabetes during a 3-year follow - up period. MATERIALS AND METHODS:The study included 309 patients with an isolated course of COPD and in combination with...
journal_title:Terapevticheskii arkhiv
pub_type: 杂志文章
doi:10.26442/00403660.2019.11.000424
更新日期:2019-11-15 00:00:00
abstract::The sensitivity, specificity, predictive value and informative value of clinical and electrocardiographic indices were assessed in patients with verified diagnoses of concomitant (17) and isolated left ventricular (23) myocardial infarction. The most informative and specific signs in terms of involvement in the right ...
journal_title:Terapevticheskii arkhiv
pub_type: 杂志文章
doi:
更新日期:1985-01-01 00:00:00
abstract:AIM:To assess efficacy of cyclopheron (Polysan production) as opisthorchiasis pretreatment in patients with chronic viral hepatitis C (CHC). MATERIAL AND METHODS:Fifteen CHC patients received cyclopheron by 6 month scheme before dehelminthization. The effect was evaluated by dynamics of clinical symptoms, results of f...
journal_title:Terapevticheskii arkhiv
pub_type: 临床试验,杂志文章
doi:
更新日期:2005-01-01 00:00:00
abstract:AIM:To study prognostic implications of a focal mature cell lesion of the bone marrow (BM) in patients with diffuse large B cell lymphosarcoma (DBLCL). MATERIAL AND METHODS:54 patients with histologically confirmed DBLCL were given first-line CHOP and CHOP-like courses from 1996 to 2003. B-cell nature of the tumor was...
journal_title:Terapevticheskii arkhiv
pub_type: 杂志文章
doi:
更新日期:2004-01-01 00:00:00
abstract:AIM:To characterize the spectrum, incidence rate and features of pulmonary pathology in HIV-infected inpatients with reference to a fall in the count of CD4-lymphocytes. MATERIAL AND METHODS:A total of 2370 patients with HIV infection admitted to Moscow infectious hospital N 2 were examined. The protocol of examinatio...
journal_title:Terapevticheskii arkhiv
pub_type: 杂志文章
doi:
更新日期:2007-01-01 00:00:00
abstract:AIM:To study changes in left atrial volume, geometry and function in myocardial infarction (MI) patients treated with beta-adrenoblocker and ACE inhibitor. MATERIAL AND METHODS:65 patients with Q-wave myocardial infarction (MI) were followed up for 6 months. Regular check-ups included clinical examination, ECG, echo-C...
journal_title:Terapevticheskii arkhiv
pub_type: 临床试验,杂志文章
doi:
更新日期:2001-01-01 00:00:00
abstract::Overall 16 patients with chronic renal failure on regular hemodialysis were examined. Of these, 8 received recombinant human erythropoietin (rhERP). A study was made of platelet aggregation and the level of some prostanoids in the blood of these patients. As the time of the treatment with rhERP was increased, the hemo...
journal_title:Terapevticheskii arkhiv
pub_type: 杂志文章
doi:
更新日期:1991-01-01 00:00:00
abstract:AIM:To detect endogenic intoxication syndrome (EIS) and to assess its severity depending on clinical manifestations of rheumatoid arthritis (RA) using laboratory tests. MATERIAL AND METHODS:Laboratory tests including analysis of synovial fluid, blood count with estimation of leucocytic intoxication index, urinalysis, ...
journal_title:Terapevticheskii arkhiv
pub_type: 杂志文章
doi:
更新日期:2006-01-01 00:00:00
abstract::The state of the renin-angiotensin system (RAS) was studied in 102 patients with chronic glomerulonephritis with the nephrotic syndrome (NS) with relation to a phase of the edematous syndrome and sodium balance. Heterogeneity of patients with NS was shown with regard to RAS activity and the circulating blood volume in...
journal_title:Terapevticheskii arkhiv
pub_type: 杂志文章
doi:
更新日期:1988-01-01 00:00:00
abstract:AIM:To study markers of myocardial electrical instability in patients with coronary heart disease (CHD) during silent myocardial ischemic episodes. SUBJECTS AND METHODS:Eighty-two patients with stable CHD (mean age 62.6 +/- 5.4 years) were examined. In addition to standard physical examination, a complex of their stud...
journal_title:Terapevticheskii arkhiv
pub_type: 杂志文章
doi:
更新日期:2010-01-01 00:00:00
abstract:AIM:To study diagnostic significance of blood serum cancer antigens levels in patients who subsequently develop pulmonary cancer (PC) and gastrointestinal cancer (GIC). MATERIAL AND METHODS:ELISA was used to study expression of tumor antigens (CEA, NSE, CA19-9, CA242, AFP) in the blood serum of 27 PC and 31 GIC patien...
journal_title:Terapevticheskii arkhiv
pub_type: 杂志文章
doi:
更新日期:2005-01-01 00:00:00