[Erythrocyte longevity in hypoplastic anemia patients undergoing splenectomy as part of combined treatment].

Abstract:

:A study was made of the survival time of erythrocytes labeled with 51Cr in 30 patients with hypoplastic anemia. In 96.7% of the patients erythrocyte survival time was reduced (from 18 to 3.6 days; an average of 11.8 days), an increase in the number of macrocytes was noted (in 83.3%). The mean volume and thickness of erythrocytes were also on an increase (in 95.8%); a decrease in the spherical index of erythrocytes was noted (in 91.6%). In this connection erythrokaryocyte proliferation enhancement was noted in 58.3% of the patients in parallel with a decrease in the total number of myelokaryocytes in 37.5%. The patients' response to multimodality therapy was different irrespective of erythrocyte survival time in the patients with hypoplastic anemia. In satisfactory preservation of medullary hemopoietic foci, particularly with polymorphous cell composition, multimodality therapy including splenectomy, produced mainly a curative effect in patients of different age with hypoplastic anemia.

journal_name

Ter Arkh

journal_title

Terapevticheskii arkhiv

authors

Rakhmatullaev AR,Karitskaia GK

subject

Has Abstract

pub_date

1987-01-01 00:00:00

pages

98-101

issue

9

eissn

0040-3660

issn

2309-5342

journal_volume

59

pub_type

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