CaM kinase control of AKT and LNCaP cell survival.

abstract：:Recently, it has been revealed that estrogen-related reproductive factors are linked with some early gene expression lesions associated with malignancy in clinically healthy breasts. Accordingly, the aim of the current study was to evaluate the association of expression levels of estrogen-related long noncoding RNAs (...

journal_title：Journal of cellular biochemistry

authors： Mansoori Y,Zendehbad Z,Askari A,Kouhpayeh A,Tavakkoly-Bazzaz J,Nariman-Saleh-Fam Z,Bastami M,Saadatian Z,Mansoori B,Yousefvand A,Mansoori H,Daraei A

更新日期：2019-06-01 00:00:00

abstract：:The low density lipoprotein receptor related protein-1 (LRP-1) is a cargo transport receptor that undergoes constitutive endocytosis and recycling. Platelet-derived growth factor-BB (PDGF-BB) binds to LRP-1 and may bridge LRP-1 to PDGF receptors. Bridging of LRP-1 to other receptors by bifunctional ligands may represe...

journal_title：Journal of cellular biochemistry

authors： Wu L,Arandjelovic S,Gonias SL

更新日期：2004-12-15 00:00:00

abstract：:Syndecans are cell-surface heparan sulfate proteoglycans, which perform a variety of functions in the cell. Most important, they are co-receptors for growth factors and mediate cell-cell and cell-matrix interactions. Four syndecans (syndecan 1-4) have been described in different species. The aim of this work was the c...

journal_title：Journal of cellular biochemistry

authors： Berndt C,Casaroli-Marano RP,Vilaró S,Reina M

更新日期：2001-01-01 00:00:00

abstract：:Recombinant adenovirus serotype 5 (Ad5) vectors have been studied extensively in preclinical gene therapy models and in a range of clinical trials. However, innate immune responses to adenovirus vectors limit effectiveness of Ad5 based therapies. Moreover, extensive pre-existing Ad5 immunity in human populations will ...

journal_title：Journal of cellular biochemistry

authors： Zaiss AK,Machado HB,Herschman HR

更新日期：2009-11-01 00:00:00

abstract：:To obtain sufficient numbers of cells for tissue engineering applications, human bone marrow-derived mesenchymal stem cells (hBM-MSC) are commonly cultured as monolayers in incubators containing room air. In this study, we investigated whether three-dimensional (3D) culture conditions and incubator gas concentrations ...

journal_title：Journal of cellular biochemistry

authors： Karlsen TA,Mirtaheri P,Shahdadfar A,Fløisand Y,Brinchmann JE

更新日期：2011-02-01 00:00:00

abstract：:Na+/D-glucose symport is a secondary active glucose transport mechanism expressed only in kidney proximal tubule and in small intestine. A monoclonal antibody that recognized the Na+/glucose symporter of pig renal brush border membranes also recognized a 75-kD protein in apical membranes isolated from highly different...

journal_title：Journal of cellular biochemistry

authors： Wu JS,Lever JE

更新日期：1989-05-01 00:00:00

abstract：:Sulfur mustard (SM) as an alkylating and vesicating agent was used for 100 years as a chemical weapon. SM as bi-functional mustard can attacks and alkylates lots of biomolecules. Different cellular mechanism and molecular pathways are responsible for damages to body tissues. Such as DNA damages, oxidative stress, Apop...

journal_title：Journal of cellular biochemistry

authors： Panahi Y,Abdolghaffari AH,Sahebkar A

更新日期：2018-01-01 00:00:00

abstract：:We have previously demonstrated that hydrogen peroxide (H(2)O(2)) treatment of murine 70Z/3 pre-B lymphocytes inhibits the immune response to lipopolysaccharide by attenuating signaling through c-Jun N-terminal kinase (JNK) activation. In the present study, we further examined the signaling intermediates responsible f...

journal_title：Journal of cellular biochemistry

authors： Lee M,Koh WS

更新日期：2003-02-15 00:00:00

abstract：:Nowadays, increased use of nanomaterials in industry and biomedicine poses potential risks to human health and the environment. Studying their possible toxicological effects is therefore of great significance. The present investigation was designed to examine the status of oxidative stress induced by nanoparticles (NP...

journal_title：Journal of cellular biochemistry

authors： Soltani A,Kahkhaie KR,Haftcheshmeh SM,Jalali Nezhad AA,Akbar Boojar MM

更新日期：2018-11-28 00:00:00

abstract：:Male pronucleus formation involves sperm nucleus decondensation and sperm chromatin remodeling. In sea urchins, male pronucleus decondensation was shown to be modulated by protein kinase C and a cdc2-like kinase sensitive to olomoucine in vitro assays. It was further demonstrated that olomoucine blocks SpH2B and SpH1 ...

journal_title：Journal of cellular biochemistry

authors： Monardes A,Iribarren C,Morin V,Bustos P,Puchi M,Imschenetzky M

更新日期：2005-10-01 00:00:00

abstract：:The 4-quinolone antibiotics nalidixic acid and ciprofloxacin are potent inhibitors of the bacterial type II topoisomerase DNA gyrase. Treatment of mouse L1210 leukemia cells with these drugs resulted in a delayed inhibition of cell proliferation. Prior to inhibition of cell proliferation, there was a time-dependent de...

journal_title：Journal of cellular biochemistry

authors： Lawrence JW,Darkin-Rattray S,Xie F,Neims AH,Rowe TC

更新日期：1993-02-01 00:00:00

abstract：:Src protein is essential for the regulation of bone turnover primarily via bone resorption because it is required in osteoclast differentiation and function. We followed temporal changes of Src protein abundance in marrow stromal cells induced to mineralize by dexamethasone (DEX), growth in cold temperature, or both. ...

journal_title：Journal of cellular biochemistry

authors： Klein BY,Levitzki R,Ben-Bassat H

更新日期：1998-06-01 00:00:00

abstract：:Fibroblast growth factor 23 (FGF23) is a phosphaturic hormone produced by bone and exerts its function in the target organs by binding the FGF receptor (FGFR) and Klotho. Since recent studies suggested that extracellular inorganic phosphate (Pi) itself triggers signal transduction and regulates gene expression in some...

journal_title：Journal of cellular biochemistry

authors： Yamazaki M,Ozono K,Okada T,Tachikawa K,Kondou H,Ohata Y,Michigami T

更新日期：2010-12-01 00:00:00

abstract：:Fibronectin (FN) is an extracellular matrix (ECM) glycoprotein that self-assembles into FN fibrils, forming a FN matrix contributing to the stiffness of the ECM. Stromal FN stiffness in cancer has been shown to impact epithelial functions such as migration, cancer metastasis, and epithelial-to-mesenchymal transition. ...

journal_title：Journal of cellular biochemistry

authors： Magdaleno C,House T,Pawar JS,Carvalho S,Rajasekaran N,Varadaraj A

更新日期：2021-01-13 00:00:00

abstract：:Oral squamous cell carcinoma (OSCC) may arise from potentially malignant oral lesions. All-trans retinoic acid (atRA), which plays a role in cell growth and differentiation, has been studied as a possible chemotherapeutic agent in the prevention of this progression. While the mechanism by which atRA suppresses cell gr...

journal_title：Journal of cellular biochemistry

authors： Acquafreda T,Nunes FD,Soprano DR,Soprano KJ

更新日期：2010-12-15 00:00:00

abstract：:Toxoplasma gondii excreted-secreted antigens (ESA) could lead to the fetal abortion especially in the early stage of pregnancy. Deficit in regulatory T cells is a critical event in the fetal abortion. Transcription factor forkhead box p3 (Foxp3) mediates differentiation and functional roles on regulatory T cells. Prev...

journal_title：Journal of cellular biochemistry

authors： Chen J,Huang C,Zhu D,Chen L,Wang J,Sun X,Hu L,Duan Y

更新日期：2018-12-01 00:00:00

abstract：:Calcium-dependent cell adhesion molecules (CAMs) mediate intercellular adhesion in epithelial cells and in preimplantation mammalian embryos. One of these molecules, cell-CAM 120/80, is found on cells as a 120-kd membrane glycoprotein and as a soluble 80-kd species in conditioned culture medium [Damsky et al: Cell 34:...

journal_title：Journal of cellular biochemistry

authors： Wheelock MJ,Buck CA,Bechtol KB,Damsky CH

更新日期：1987-07-01 00:00:00

abstract：:9-cis Retinoic acid (RA) induces gene expression in neuroblastoma cells more effectively and with different kinetics than other RA isomers, and could be acting in part through Retinoid X Receptors (RXRs). The aim of this study was to characterise the effects of an RXR agonist and RXR homodimer antagonist on the induct...

journal_title：Journal of cellular biochemistry

authors： Hewson QC,Lovat PE,Pearson AD,Redfern CP

更新日期：2002-01-01 00:00:00

abstract：:Successful implantation and placentation requires that extravillous cytotrophoblast acquires an endovascular phenotype and remodels uterine spiral arteries. Defects in this mechanism correlate with severe obstetric complications as implantation failure and preeclampsia. Lysophosphatidic acid (LPA) participates in embr...

journal_title：Journal of cellular biochemistry

authors： Beltrame JS,Sordelli MS,Cañumil VA,Franchi AM,Ribeiro ML

更新日期：2018-01-01 00:00:00

abstract：:Hepatocyte growth factor (HGF) is known to have a number of biological properties including promoting tumor progression of human carcinomas. Metastasis involves a number of events that are attributed to induction by paracrine factors such as HGF. Identification of natural inhibitors of these events would allow better ...

journal_title：Journal of cellular biochemistry

authors： Uchiyama A,Essner R,Doi F,Nguyen T,Ramming KP,Nakamura T,Morton DL,Hoon DS

更新日期：1996-09-15 00:00:00

abstract：:We investigated the role of tetracycline in the transcriptional regulation of matrix metalloproteinases. Using interleukin-1beta (IL-1) induced stromelysin as a model system, we describe the repression of the endogenous stromelysin RNA accumulation, as well as the transcriptional inhibition of various stromelysin prom...

journal_title：Journal of cellular biochemistry

authors： Jonat C,Chung FZ,Baragi VM

更新日期：1996-03-01 00:00:00

abstract：:Recent studies have shown that only breast cancer epithelial cells with intact p53 can induce metallothionein (MT) synthesis after exposure to metals. In this study, the potential role of p53 on regulation of MT was investigated. Results demonstrate that zinc and copper increased metal response elements (MREs) activit...

journal_title：Journal of cellular biochemistry

authors： Ostrakhovitch EA,Olsson PE,von Hofsten J,Cherian MG

更新日期：2007-12-15 00:00:00

abstract：:There is a well-known relationship between the cholinergic system and learning, memory, and other common cognitive processes. The process for researching and developing new drugs has lead researchers to repurpose older ones. This study investigated the effects of ebselen on the activity of acethylcholinesterase (AChE)...

journal_title：Journal of cellular biochemistry

authors： Martini F,Pesarico AP,Brüning CA,Zeni G,Nogueira CW

更新日期：2018-07-01 00:00:00

abstract：:The objective of this study was to evaluate the genotoxic and mutagenic effects of the toxins present in Lachesis muta muta's venom on human peripheral blood leukocytes and the protective potential of ascorbic acid on DNA fragmentation. The venom of L. muta muta was incubated in different concentrations (1, 2.5, 5, 7....

journal_title：Journal of cellular biochemistry

authors： Cardoso Trento MV,de Faria Eleutério MW,Silva Abreu T,Andrade Machado GH,Cesar PHS,Assaid Simão A,Marcussi S

更新日期：2019-03-01 00:00:00

abstract：:Recently, glioma stem cells have been identified as the main cause of glioma propagation and recurrence and a number of several cell markers have been indicated as putative GSC markers. In the present work, a retrospective study to evaluate the prognostic potential of ability to generate GSCs in our series of 15 gliob...

journal_title：Journal of cellular biochemistry

authors： Miconi G,Palumbo P,Dehcordi SR,La Torre C,Lombardi F,Evtoski Z,Cimini AM,Galzio R,Cifone MG,Cinque B

更新日期：2015-05-01 00:00:00

abstract：:We investigated the association of DNA polymerase and DNA primase activity with the nuclear matrix in HeLa S3 cells diluted with fresh medium after having been cultured without any medium change for 7 days. Flow cytometric analysis demonstrated that just before dilution about 85% of the cells were in the G1 phase of t...

journal_title：Journal of cellular biochemistry

authors： Martelli AM,Capitani S,Neri LM

更新日期：1998-10-01 00:00:00

abstract：:Protein phosphatase 2A (PP2A) is an important enzyme within various signal transduction pathways. The present study was investigated PP2A mediates JS-K-induced apoptosis by affecting Bcl-2 family protein. JS-K showed diverse inhibitory effects in five HCC cell lines, especially HepG2 cells. JS-K caused a dose- and tim...

journal_title：Journal of cellular biochemistry

authors： Liu L,Huang Z,Chen J,Wang J,Wang S

更新日期：2018-08-01 00:00:00

abstract：:The conversion of expandable liver progenitor cells into pancreatic beta cells would provide a renewable cell source for diabetes cell therapy. Previously, we reported the establishment of liver epithelial progenitor cells (LEPCs). In this work, LEPCs were modified into EGFP/Pdx-1 LEPCs, cells with stable expression o...

journal_title：Journal of cellular biochemistry

authors： Jin CX,Li WL,Xu F,Geng ZH,He ZY,Su J,Tao XR,Ding XY,Wang X,Hu YP

更新日期：2008-05-01 00:00:00

abstract：:Amplification of MYCN is one of the most important prognostic markers for neuroblastoma and is correlated with rapid tumor progression and poor prognosis. MYCN belongs to the Myc/Max/Mad/Mnt network of proteins that regulate proliferation, apoptosis, and differentiation. It is well established that MYCN is downregulat...

journal_title：Journal of cellular biochemistry

authors： Smith AG,Popov N,Imreh M,Axelson H,Henriksson M

更新日期：2004-08-15 00:00:00

abstract：:Osteopontin is a secreted glycoprotein with adhesive and migratory functions. Cellular interactions with osteopontin are mediated through integrin receptors which recognize the RGD domain. Recently, CD44, a non-integrin, multifunctional adhesion molecule was identified as an osteopontin receptor. CD44 is a ubiquitous ...

journal_title：Journal of cellular biochemistry

authors： Smith LL,Greenfield BW,Aruffo A,Giachelli CM

更新日期：1999-04-01 00:00:00