CD44 is not an adhesive receptor for osteopontin.

abstract：:Endogenous peptides play crucial roles in various biological processes. Their effects on the pathogenesis of human infantile hemangioma remains poorly understood. In this study, we construct a comparative peptidomic profiling between human infantile hemangioma tissue and matched normal skin using liquid chromatography...

journal_title：Journal of cellular biochemistry

authors： Li Q,Li J,Chen L,Gao Y,Li J

更新日期：2018-06-01 00:00:00

abstract：BACKGROUND:Inflammatory bowel disease (IBD) is one of the most important immune-mediated disorders of the gastrointestinal tract. Besides, IBD is associated with numerous extraintestinal complications such as venous thromboembolism (VTE), an important risk factor for vascular complications, which results in the increas...

journal_title：Journal of cellular biochemistry

authors： Asadzadeh-Aghdaei H,Mashayekhi K,Koushki K,Azimzadeh P,Rostami-Nejad M,Amani D,Chaleshi V,Haftcheshmeh SM,Sahebkar A,Zali MR

更新日期：2019-09-01 00:00:00

abstract：:MicroRNA-205 (miR-205) is involved in various physiological and pathological processes, but its biological function in follicular atresia remains unclear. In this study, we investigated miR-205 expression in mouse granulosa cells (mGCs) and analyzed its functions in primary mGCs by performing a series of in vitro expe...

journal_title：Journal of cellular biochemistry

authors： Zhang P,Wang J,Lang H,Wang W,Liu X,Liu H,Tan C,Li X,Zhao Y,Wu X

更新日期：2018-12-16 00:00:00

abstract：OBJECTIVE:To investigate the correlation between serum protein level of insulin growth factor 1 (IGF-1) and the degree of liver fibrosis in patients with chronic hepatitis C (CHC) combined with type 2 diabetes mellitus (T2DM). METHODS:The cases are divided into four groups. Then serum levels of IFG-1, alanine aminotra...

journal_title：Journal of cellular biochemistry

authors： Cao LH,Lu FM,Lu XJ,Zhu LY

更新日期：2018-11-01 00:00:00

abstract：:Secreted phosphoprotein 24 kD (spp24) is a bone matrix protein isolated during attempts to identify osteogenic proteins. It is not osteogenic but performs other important roles in the regulation of bone metabolism, at least in part, by binding to and affecting the activity of members of the BMP/TGF-β family of cytokin...

journal_title：Journal of cellular biochemistry

authors： Tian H,Li CS,Zhao KW,Wang JC,Duarte ME,David CL,Phan K,Atti E,Brochmann EJ,Murray SS

更新日期：2015-04-01 00:00:00

abstract：:Acid-electrolyzed functional water (FW) is obtained through the electrolysis of sodium chloride solution. Stimulation of the human fibroblastic cell line HeLa by FW led to the augmented secretion of basic fibroblast growth factor (bFGF). Immunoprecipitation followed by Western blot analysis revealed that both high and...

journal_title：Journal of cellular biochemistry

authors： Motozawa K,Motoyoshi M,Saiki A,Sasaki H,Shimizu N,Asano M

更新日期：2018-09-01 00:00:00

abstract：:AKT and its substrate BAD have been shown to promote prostate cancer cell survival. Agonists, such as carbachol, and hormones that increase intracellular calcium concentration can activate AKT leading to cancer cell survival. The LNCaP prostate cancer cells express the carbachol-sensitive M(3) -subtype of G protein-co...

journal_title：Journal of cellular biochemistry

authors： Schmitt JM,Smith S,Hart B,Fletcher L

更新日期：2012-05-01 00:00:00

abstract：:Breast cancer, the most common cancer in women worldwide, is associated with high mortality. The long non-coding RNAs (lncRNAs) with a little capacity of coding proteins is playing an increasingly important role in the cancer paradigm. Accumulating evidences demonstrate that lncRNAs have crucial connections with breas...

journal_title：Journal of cellular biochemistry

authors： He Y,Li X,Meng Y,Fu S,Cui Y,Shi Y,Du H

更新日期：2019-10-01 00:00:00

abstract：:Angiogenesis is the central pathological process in hepatocellular carcinoma (HCC), and its progression is affected by tumor cells and the microenvironment. Activated hepatic stellate cells (aHSCs) are the most significant stromal cells involved in HCC. This study was aimed to explore the effects and mechanisms of aHS...

journal_title：Journal of cellular biochemistry

authors： Lin N,Meng L,Lin J,Chen S,Zhang P,Chen Q,Lin Y

更新日期：2020-02-01 00:00:00

abstract：:In the present study, we have investigated dexamethasone and insulin regulation of the expression of adipose-specific mRNA, namely, glycerophosphate dehydrogenase (G3PDH) and adipsin, at different stages of differentiation. During adipose conversion, insulin promotes an accumulation of G3PDH mRNA which is linked to ce...

journal_title：Journal of cellular biochemistry

authors： Moustaid N,Lasnier F,Hainque B,Quignard-Boulange A,Pairault J

更新日期：1990-04-01 00:00:00

abstract：:The role of regucalcin in the regulation of osteoblastic cell function was investigated. Osteoblastic MC3T3-E1 cells with subconfluent monolayers were cultured in a medium containing regucalcin (10(-10)-10(-8) M) without fetal bovine serum (FBS). The proliferation of osteoblastic cells was not significantly altered in...

journal_title：Journal of cellular biochemistry

authors： Yamaguchi M,Kobayashi M,Uchiyama S

更新日期：2005-10-15 00:00:00

abstract：:Diacylglycerol (DG) kinase (DGK), which phosphorylates DG to generate phosphatidic acid (PA), consists of ten isozymes (α-к). Recently, we identified a novel small molecule inhibitor, CU-3, that selectively inhibits the activity of the α isozyme. In addition, we newly obtained Compound A, which selectively and strongl...

journal_title：Journal of cellular biochemistry

authors： Yamaki A,Akiyama R,Murakami C,Takao S,Murakami Y,Mizuno S,Takahashi D,Kado S,Taketomi A,Shirai Y,Goto K,Sakane F

更新日期：2019-06-01 00:00:00

abstract：:Cranial sutures are important growth sites of the skull. During suture closure, the dura mater is one of the most important sources of various positive and negative regulatory signals. Previous results indicate that TGF-beta2 from dura mater strongly accelerates suture closure, however, its exact regulatory mechanism ...

journal_title：Journal of cellular biochemistry

authors： Lee SW,Choi KY,Cho JY,Jung SH,Song KB,Park EK,Choi JY,Shin HI,Kim SY,Woo KM,Baek JH,Nam SH,Kim YJ,Kim HJ,Ryoo HM

更新日期：2006-07-01 00:00:00

abstract：:p38 mitogen-activated protein kinase (MAPK) is of fundamental importance in a cell's response to environmental stresses, cytokines and DNA damage. p38 resides in the cytoplasm of resting cells, and translocates into the nucleus upon activation, yet the exact mechanisms remain largely unclear. We show here that the pho...

journal_title：Journal of cellular biochemistry

authors： Gong X,Ming X,Deng P,Jiang Y

更新日期：2010-08-15 00:00:00

abstract：:The complex nuclear structure of somatic cells is important to epigenomic regulation, yet little is known about nuclear organization of human embryonic stem cells (hESC). Here we surveyed several nuclear structures in pluripotent and transitioning hESC. Observations of centromeres, telomeres, SC35 speckles, Cajal Bodi...

journal_title：Journal of cellular biochemistry

authors： Butler JT,Hall LL,Smith KP,Lawrence JB

更新日期：2009-07-01 00:00:00

abstract：:Genistein, a natural isoflavone phytoestrogen present in soybeans, caused a dose-dependent growth inhibition of the two hormone-sensitive cell lines T47D and ZR75.1 and of the two hormone-independent cell lines MDAMB-231 and BT20. Flow cytometric analysis of cells treated for 4 days with 15 and 30 microM genistein sho...

journal_title：Journal of cellular biochemistry

authors： Cappelletti V,Fioravanti L,Miodini P,Di Fronzo G

更新日期：2000-09-14 00:00:00

abstract：:Mouse embryonic fibroblast (MEF) cells prepared from transgenic mice overexpressing a cancer-specific and growth-related cell surface NADH oxidase with protein disulfide-thiol interchange activity grew at rates approximately twice those of wild-type embryonic fibroblast cells. Growth of transgenic MEF cells overexpres...

journal_title：Journal of cellular biochemistry

authors： Yagiz K,Wu LY,Kuntz CP,James Morré D,Morré DM

更新日期：2007-05-15 00:00:00

abstract：:Phospholipase C-gamma1 (PLCgamma1) plays a critical role in cell growth and proliferation by generating the second messengers, diacylglycerol and 1, 4, 5-inositol triphosphate. To investigate the roles of Src homology domain 2 and domain 3 of PLCgamma1 in PLCgamma1-mediated cell signaling, we characterized some protei...

journal_title：Journal of cellular biochemistry

authors： Bae JY,Ahn SJ,Lee JE,Kim JE,Han MR,Han W,Kim SW,Shin HJ,Lee SJ,Park D,Noh DY

更新日期：2005-04-01 00:00:00

abstract：:Long non-coding RNAs (lncRNAs) can participate in the pathological process of multiple myeloma (MM) via regulation of specific gene expression and function. This research aimed to study the role of MALAT-1 and the underlying mechanism in MM. In this study, the expression of MALAT-1 and HMGB1 protein in the bone marrow...

journal_title：Journal of cellular biochemistry

authors： Gao D,Lv AE,Li HP,Han DH,Zhang YP

更新日期：2017-10-01 00:00:00

abstract：:Skeletal muscle atrophy is a well-known adverse effect of chronic treatment with glucocorticoids and it also occurs when stress conditions such as sepsis and cachexia increase the release of endogenous glucocorticoids. Although the mechanisms of action of these hormones have been elucidated, the possible molecular mec...

journal_title：Journal of cellular biochemistry

authors： Massaccesi L,Goi G,Tringali C,Barassi A,Venerando B,Papini N

更新日期：2016-08-01 00:00:00

abstract：:Previous studies demonstrated that, upon attaining confluence, a clone of the renal epithelial cell, LLC-PK1, expressed progressively binding sites for the lectin Dolichos biflorus agglutinin (DBA) at the apical cell surface. Activation of cAMP-dependent protein kinase enhanced surface expression dramatically. The goa...

journal_title：Journal of cellular biochemistry

authors： Amsler K

更新日期：1993-08-01 00:00:00

abstract：:Treatment of adherent peripheral blood mononuclear cells (PBMCs) with macrophage colony stimulating factor (M-CSF) and receptor activator of NF-kappaB ligand (RANKL) stimulates the formation of multinucleate osteoclast-like cells. Treatment with M-CSF alone results in the formation of macrophage-like cells. Through th...

journal_title：Journal of cellular biochemistry

authors： Day CJ,Kim MS,Stephens SR,Simcock WE,Aitken CJ,Nicholson GC,Morrison NA

更新日期：2004-02-01 00:00:00

abstract：:Platelet-derived growth factor (PDGF) stimulates the expression of a number of genes associated with entry of quiescent Balb/c-3T3 fibroblasts into the cell cycle. We determined that two of these genes, c-myc and c-fos, are induced equivalently in medium supplemented with platelet-poor plasma (PPP) and either PDGF-BB ...

journal_title：Journal of cellular biochemistry

authors： Coats SR,Olson JE,Pledger WJ

更新日期：1992-03-01 00:00:00

abstract：:In our previous study, preliminary data indicates that Poria cocos polysaccharides (PCP) shows beneficial hepatoprotection against acetaminophen (APAP)-induced liver injury in mice. However, biological molecular mechanism warrants to be further discussed. In current study, a number of biochemical tests and immunoassay...

journal_title：Journal of cellular biochemistry

authors： Wu K,Guo C,Yang B,Wu X,Wang W

更新日期：2019-05-01 00:00:00

abstract：:During embryonic development, the hematopoietic system is the first to generate terminally differentiated, functional cell types. The urgent necessity for the early formation of blood and blood vessels during embryogenesis means that the induction, expansion, and maturation of these systems must be rapidly and precise...

journal_title：Journal of cellular biochemistry

authors： Snyder A,Fraser ST,Baron MH

更新日期：2004-10-01 00:00:00

abstract：:AIMP1 was first found as a factor associated with the aminoacyl-tRNA synthetase (ARS) complex. However, it is also secreted and acts on different target cells such as endothelial cells, macrophages, and fibroblasts as an extracellular regulator, respectively, of angiogenesis, inflammatory responses and dermal regenera...

journal_title：Journal of cellular biochemistry

authors： Jackson VC,Dewilde S,Albo AG,Lis K,Corpillo D,Canepa B

更新日期：2011-07-01 00:00:00

abstract：:Escherichia coli is frequently exploited for genetic manipulations and heterologous gene expression studies. We have evaluated the metabolic profile of E. coli strain BL21 (DE3) RIL CodonPlus after genetic modifications and subjecting to the production of recombinant protein. Three genetically variable E. coli cell ty...

journal_title：Journal of cellular biochemistry

authors： Nadeem MS,Razeeth M,Choudhry HMZ,Anwar F,Zamzami MA,Murtaza BN,Al-Abbasi FAM,Khan MI,Shakoori AR

更新日期：2020-01-01 00:00:00

abstract：:Reveromycin A (RM-A), a small natural product isolated from Streptomyces bacteria, is a potential osteoporosis therapeutic in that it specifically induces apoptosis in osteoclasts but not osteoblasts. The purpose of the study presented here was to further elucidate the intracellular mechanisms of RM-A death effects in...

journal_title：Journal of cellular biochemistry

authors： Mead B,Morgan H,Mann-Knowlton A,Tedeschi L,Sloan C,Lang S,Hines C,Gragg M,Stofer J,Riemann K,Derr T,Heller E,Collins D,Landis P,Linna N,Jones D

更新日期：2015-08-01 00:00:00

abstract：:Neuropathic pain is a kind of pain caused by primary or secondary impairment or dysfunction of peripheral or central nervous system. Patients with neuropathic pain were often with poor clinical outcome. We screened the differentially expressed genes between sciatic nerve injury and dorsal root ganglion gene in the sha...

journal_title：Journal of cellular biochemistry

authors： Yang JA,He JM,Lu JM,Jie LJ

更新日期：2018-06-01 00:00:00

abstract：:Cells release exosomes to transfer various molecules to other cells. Exosomes are involved in a number of physiological and pathological processes. They are emerging great potential utility for diseases diagnosis and treatment recently. However, the internalization and intracellular trafficking of exosomes have not be...

journal_title：Journal of cellular biochemistry

authors： Tian T,Wang Y,Wang H,Zhu Z,Xiao Z

更新日期：2010-10-01 00:00:00