Abstract:
:A retrospective study of 160 pediatric subjects, aged 32-410 weeks after conception, was conducted to determine the normal developmental patterns of the human cerebellum by means of magnetic resonance (MR) imaging. On the basis of axial T2-weighted spin-echo images (repetition time, 3,000 msec; echo time, 120 msec), which provided the best contrast between gray matter and white matter, five distinct developmental stages were defined. At term, the medial lemnisci as well as the parasagittal cerebellum were myelinated. The appearance of myelin in the middle cerebellar peduncles and the basilar pons preceded that in the corpus medullare of the cerebellum. The normal age ranges for the different stages were defined with statistical analysis. These ranges are applicable to the daily routine of image interpretation. The sequence of myelination in the cerebellum observed at MR imaging correlates with the known patterns observed in pathologic studies but lags behind by an average of 6 months.
journal_name
Radiologyjournal_title
Radiologyauthors
Stricker T,Martin E,Boesch Cdoi
10.1148/radiology.177.2.2217780subject
Has Abstractpub_date
1990-11-01 00:00:00pages
431-5issue
2eissn
0033-8419issn
1527-1315journal_volume
177pub_type
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