Injectable corticosteroid and local anesthetic preparations: a review for radiologists.

Abstract:

:Corticosteroids and local anesthetics are some of the most commonly administered medications in radiology departments. These medications have marked variability in their formulations, which may increase their adverse event profile for specific procedures. In particular, certain corticosteroid preparations are associated with adverse central nervous system (CNS) sequelae. This is most likely due to distal embolization by particulate formulations. Nonparticulate steroid formulations are not associated with such events. Local anesthetics have severe CNS and cardiac adverse effects if injected intravascularly and have recently been associated with intraarticular chondrolysis if used in large doses. This review discusses these medications with particular emphasis on their established and postulated adverse effects. The administering radiologist should be aware of these potential effects and how best to reduce their occurrence.

journal_name

Radiology

journal_title

Radiology

authors

MacMahon PJ,Eustace SJ,Kavanagh EC

doi

10.1148/radiol.2523081929

subject

Has Abstract

pub_date

2009-09-01 00:00:00

pages

647-61

issue

3

eissn

0033-8419

issn

1527-1315

pii

252/3/647

journal_volume

252

pub_type

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