Abstract:
:The effects of stress, which varies throughout an academic year, on proinflammatory and antiinflammatory cytokines were examined in 44 medical students. This was tested by comparing stimulated cytokines during a baseline period, stress period, and poststress vacation period. During the stress period, compared with the baseline period, levels of IL-6 were reduced, while levels of IL-10 were elevated. During the poststress vacation period, compared with the stress period, levels of IL-6 and TNF-α were increased. However, the changes in stress-related psychological and physiological variables were not significantly associated with changes in levels of proinflammatory and antiinflammatory cytokines. These results suggest that vacation is more likely to have a counterstress effect on proinflammatory cytokines than on an antiinflammatory cytokine and that a stressor may affect changes in immune function independently of self-reported stress.
journal_name
Psychophysiologyjournal_title
Psychophysiologyauthors
Koh KB,Lee YJ,Beyn KM,Chu SH,Kim DM,Seo WYdoi
10.1111/j.1469-8986.2012.01409.xsubject
Has Abstractpub_date
2012-09-01 00:00:00pages
1290-7issue
9eissn
0048-5772issn
1540-5958journal_volume
49pub_type
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