Abstract:
:We describe a simple method for computer quantification of eye movement (EM) potentials during REM sleep. This method can be applied by investigators using either period-amplitude (PA) or Fast Fourier Transform (FFT) spectral EEG analysis without special hardware or computer programming. It provides good correlations with visual ratings of EM in baseline sleep and after administration of GABAergic hypnotics. We present baseline data for both PA and FFT measures for 16 normal subjects, studied for 5 consecutive nights. Both visually rated and computer-measured EM density (EMD) showed high night-to-night correlations across baseline and drug nights and the computer measures detected the EMD suppression that is produced by GABAergic drugs. Measurement of EM in addition to stage REM provides biologically significant information and application of this simple computer method, which does not require pattern recognition algorithms or special hardware, could provide reliable data that can be compared across laboratories.
journal_name
Psychophysiologyjournal_title
Psychophysiologyauthors
Tan X,Campbell IG,Feinberg Idoi
10.1017/s0048577201000816subject
Has Abstractpub_date
2001-05-01 00:00:00pages
512-6issue
3eissn
0048-5772issn
1540-5958journal_volume
38pub_type
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