A simple method for computer quantification of stage REM eye movement potentials.

Abstract:

:We describe a simple method for computer quantification of eye movement (EM) potentials during REM sleep. This method can be applied by investigators using either period-amplitude (PA) or Fast Fourier Transform (FFT) spectral EEG analysis without special hardware or computer programming. It provides good correlations with visual ratings of EM in baseline sleep and after administration of GABAergic hypnotics. We present baseline data for both PA and FFT measures for 16 normal subjects, studied for 5 consecutive nights. Both visually rated and computer-measured EM density (EMD) showed high night-to-night correlations across baseline and drug nights and the computer measures detected the EMD suppression that is produced by GABAergic drugs. Measurement of EM in addition to stage REM provides biologically significant information and application of this simple computer method, which does not require pattern recognition algorithms or special hardware, could provide reliable data that can be compared across laboratories.

journal_name

Psychophysiology

journal_title

Psychophysiology

authors

Tan X,Campbell IG,Feinberg I

doi

10.1017/s0048577201000816

subject

Has Abstract

pub_date

2001-05-01 00:00:00

pages

512-6

issue

3

eissn

0048-5772

issn

1540-5958

journal_volume

38

pub_type

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