[Proliferative vitreoretinopathy: new discoveries in pathophysiology and therapy].

Abstract:

:In this article the authors review present knowledge concerning the pathogenesis of proliferative vitreoretinopathy (PVR). The function of cells such as macrophages, fibroblasts, retinal pigment epithelial cells, and glial cells, as well as their interaction with constituents of the extracellular matrix such as fibronectin, vitronectin, and factor XIII, are described. Current data on growth factor involvement in the pathogenesis of PVR are explained. Attention is focused on the histopathological differences between traumatic and idiopathic membranes, "young" and "old" membranes, and PVR and diabetic membranes. On the basis of the findings presented, the importance of the breakdown of the blood-retinal barrier, the participation of the coagulation system, and immunological aspects of membrane formation are discussed. Conceivable new strategies for medical treatment of PVR are proposed.

journal_name

Klin Monbl Augenheilkd

authors

Wiedemann P,Weller M,Heimann K

doi

10.1055/s-2008-1046292

subject

Has Abstract

pub_date

1990-11-01 00:00:00

pages

355-61

issue

5

eissn

0023-2165

issn

1439-3999

journal_volume

197

pub_type

杂志文章,评审
  • [Clinical findings in phakolytic glaucoma (author's transl)].

    abstract::1300 enucleated globes were examined from 1966-1974: Among these 20 eyes (1.5%) revealed a "phacolytic glaucoma" histologically. The clinical diagnosis before enucleation were "secondary glaucoma" or "absolute glaucoma" (19) and once "uveitis dolorosa". "Phakolysis" was considered in only 3 eyes. 15 cases revealed sur...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:

    authors: Völcker HE,Naumann G

    更新日期:1975-05-01 00:00:00

  • [Biometry of the anterior chamber of the eye in Nd:YAG laser iridectomy].

    abstract::In a prospective clinical study covering 41 eyes (28 patients) with narrow-angle glaucoma the central and peripheral anterior chamber depths were determined biomicroscopically before and after Nd:YAG laser iridectomy. In 29 eyes the central anterior chamber depth was also measured by ultrasonography. In contrast to th...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-2008-1046142

    authors: Schrems W,Hofmann G,Krieglstein GK

    更新日期:1990-03-01 00:00:00

  • [Contributions to the surgical technique of external dacryocystorhinostomy (author's transl)].

    abstract::The authors describe some modifications of the surgical technique of external dacryocystorhinostomy. The preliminary exploration methods and their evaluation are considered. An arched skin incision is used for a more anatomical dissection to approach the lacrimal sac. The following bone trepanation is then made with b...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:

    authors: Menezo JL,Francés J,Suárez R

    更新日期:1975-01-01 00:00:00

  • [Nosocomial pseudomonas aeruginosa-associated keratitis in soft contact lens wearer].

    abstract:BACKGROUND:Pseudomonas aeruginosa is the most common cause of bacterial-associated keratitis in soft contact lens wearers, due to wrong use of soft contact lenses. Problems are often severe corneal ulcers and even corneal perforations. We report on a soft contact lens wearer with credibly correct use of soft contact le...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-2003-812639

    authors: Grünauer-Kloevekorn C,Wilhelm F,Duncker GI,Hammer T

    更新日期:2004-01-01 00:00:00

  • [Histology and therapy of diabetic traction detachment].

    abstract::Diabetic tractional detachment of the retina is caused by shrinking processes of the vitreous, which at most detaches only partially, and by shrinking of epiretinal proliferations. The shrinking of the vitreous results in tractional forces working centripetally and toward the base of the vitreous. The shrinking of the...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-2008-1054438

    authors: Faulborn J

    更新日期:1984-03-01 00:00:00

  • Internal Limiting Membrane Flap Techniques for the Repair of Large Macular Holes: a Short-Term Follow-up of Anatomical and Functional Outcomes.

    abstract::Background To evaluate the technique of inverted internal limiting membrane (ILM) flaps for the management of large macular holes and autologous ILM free flaps for non-closing macular holes. Patients and methods All macular holes were treated with pars plana vitrectomy and dual blue assisted ILM flap technique. The in...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-0042-119694

    authors: Guber J,Lang C,Valmaggia C

    更新日期:2017-04-01 00:00:00

  • [Bivalent glaucoma therapy with pilocarpine and adrenaline - advantages of the combination piladren (author's transl)].

    abstract::A comparative trial was performed on 56 glaucomatous eyes - piladren gave usually a better pressure-reducing effect than pilocarpine alone or pilocarpine and epinephrine/adrenaline from separate bottles. The main possibilites of medical glaucoma therapy are mentioned and subjective and objective advantages and disadva...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 临床试验,杂志文章

    doi:

    authors: Unterkircher K

    更新日期:1976-10-01 00:00:00

  • Transepithelial short circuit currents in human and porcine isolated ciliary bodies: effect of acetazolamide and epinephrine.

    abstract:BACKGROUND:To investigate in human and porcine isolated ciliary bodies the effect of acetazolamide and epinephrine on ciliary transepithelial ionic currents (a parameter linked to aqueous humor production). MATERIAL AND METHODS:Isolated ciliary bodies were mounted in a Ussing-type chamber to measure transepithelial po...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-2003-38168

    authors: Wu R,Flammer J,Haefliger I

    更新日期:2003-03-01 00:00:00

  • [Keratectomy and cataract extraction in Terrien disease].

    abstract::In a 36-year-old patient with bilateral Terrien's disease, surgery to improve vision in the right eye, which was in Stage V, was no longer possible. In Stage III a thoroughgoing keratectomy parallel to the limbus was performed, in combination with cataract extraction and coreplasty. Even though Descemet's membrane was...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-2008-1054338

    authors: Schulze F

    更新日期:1985-11-01 00:00:00

  • [New trends in tonometry].

    abstract:BACKGROUND:Though the knowledge about the risk of elevated intraocular pressure for pathogenesis for development and progress of glaucoma is more than 400 years old. It took another 300 years before by means of tonometry this elevation could be quantified. After discussion of the key words it is our aim to demonstrate ...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章,评审

    doi:10.1055/s-2006-927161

    authors: Draeger JA,Schwenteck T,Ruokonen PC

    更新日期:2006-10-01 00:00:00

  • [Contact lenses in the treatment of badly injured eyes (author's transl)].

    abstract::Serious eye injuries occur mostly in the spheres of traffic, work and play. There is an inverse relationship between the length of the wound and the visual acuity. Various authors' groupings according to the type of injury, and the relationship between severity and acuity obtained are given and comprehensively describ...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:

    authors: Geyer OC

    更新日期:1976-09-01 00:00:00

  • [The Fieldmaster-200 computer perimeter: a comparative, controlled clinical study of its sensitivity and specificity in glaucomatous field defects (author's transl)].

    abstract::The central visual fields of 119 glaucomatous eyes (78 patients) were evaluated under controlled conditions using the Goldmann kinetic perimeter and the Fieldmaster-200 automatic supra-threshold computer perimeter. Where there were qualitative differences between the two instruments, the high-resolution program 61 of ...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 临床试验,杂志文章

    doi:10.1055/s-2008-1057325

    authors: Krieglstein GK,Glaab E,Gramer E

    更新日期:1981-11-01 00:00:00

  • [Minimizing induction of astigmatism in preoperative spherical cornea a. by mini-incision surgery with foldable IOL and b. by corneal tunnel incision with limbal relaxing incision].

    abstract:BACKGROUND:In case of a spheric cornea preoperatively the refractive effect of a clear corneal cataract incision is undesirable. We studied two actual techniques to minimize the surgically induced astigmatism. PATIENTS AND METHODS:Temporal clear corneal incision was performed in 77 patients with practically spherical ...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 临床试验,杂志文章

    doi:10.1055/s-2008-1034692

    authors: Müller-Jensen K,Fischer P

    更新日期:1999-09-01 00:00:00

  • The Assessment of Blood Flow Velocities in Retinal Collaterals in Diabetic Retinopathy.

    abstract:PURPOSE:Diabetic retinopathy (DR) is a microvascular disease characterized by capillary dropout and resultant retinal ischemia which then leads to retinal vascular remodeling. Our goal was to assess blood flow velocities in retinal collateral vessels in healthy and diabetic subjects with various stages of DR. METHODS:...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:10.1055/a-0861-9675

    authors: Somfai GM,Campagnoli TR,Tian J,Gerding H,Smiddy WE,DeBuc D

    更新日期:2019-04-01 00:00:00

  • [O'Connor's surgical method in abducens nerve paralysis].

    abstract::Eighteen patients who underwent surgery for nervus abducens paresis (NAP), were kept under observation for up to 23 years after the operation. Three patients had paresis of both nerves. The operation, employing O'Connor's method (11 patients) included the grafting of split inferior and superior rectus muscles on to th...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-2008-1054369

    authors: Miettinen P,Aine E,Partanen M

    更新日期:1985-11-01 00:00:00

  • [Evaluation of Changes in Corneal Biomechanics in Patients with Systemic Sclerosis].

    abstract:INTRODUCTION:Our study compares the biomechanical properties of the cornea in patients with long-term pre-existing (for at least 10 years) systemic sclerosis (SSc) with those of healthy suspects. MATERIAL/METHODS:The examination was performed in 14 systemic SSc patients and 38 healthy volunteers. Non-invasive assessme...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-0043-125078

    authors: Zimmermann N,Brandt S,Brünner J,Erb C

    更新日期:2019-06-01 00:00:00

  • [Prognostic relevance of histopathologic parameters in malignant melanoma of the choroid using the pTNM classification].

    abstract::On the basis of data collected over a period of 22 years from 376 patients enucleated at the Eye Clinic of Karl Marx University, Leipzig because of malignant choroidal melanoma, the prognostic significance and reliability of various histopathological characteristics was investigated. The most significant characteristi...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-2008-1050116

    authors: Göllnitz R,Lommatzsch PK

    更新日期:1988-04-01 00:00:00

  • [Differential diagnosis of leukokoria in opaque media].

    abstract::In the presence of leukokoria the diagnosis of retinoblastoma is usually easy when the mediae are transparent. If they are not, however, one is frequently obliged to enucleate a painful or useless eye in order to rule out this diagnosis. In a series of eight cases having undergone enucleation for this reason at the La...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-2008-1057514

    authors: Balmer A,Uffer S,Gailloud C

    更新日期:1980-04-01 00:00:00

  • [Corneal endothelial damage in congenital and juvenile glaucoma].

    abstract::Corneal changes are typical for infantile glaucoma. In newborns, Descemet's membrane and the stroma are still soft, and distend when intraocular pressure rises. Cell counts were performed under the reflecting microscope to determine whether the endothelium is affected when corneal diameter increases and changes occur ...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-2008-1050052

    authors: Wenzel M,Krippendorff U,Hunold W,Reim M

    更新日期:1989-12-01 00:00:00

  • [Foreign body granuloma after lower eyelid avulsion and surgical revision with silicone tube splint].

    abstract:BACKGROUND:Foreign-body-reactions with granulomas after use of silicone-containing biomaterials are of clinical importance [4]. HISTORY AND SIGNS:A 4-year old patient entered our hospital with a reddish vascularised tumor. The tumor's origin was in the conjunctiva of the nasal lid-angle of the right eye. THERAPY AND ...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-2000-10550

    authors: Bär S,Hammer U,Struck HG,Stein A,Holzhausen HJ,Duncker GI

    更新日期:2000-04-01 00:00:00

  • [Real-time monitoring of a femtosecond laser in Sub-Bowman Keratomileusis on human donor eyes using OCT].

    abstract:PURPOSE:In LASIK (laser in situ keratomileusis) the thickness of the corneal flap is important since it is the residual corneal bed that determines corneal stability. The introduction of real-time OCT visualisation of the corneal layers during the fs-laser cut should enable the surgeon to control and monitor the positi...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-0028-1109682

    authors: Kermani O,Oberheide U,Will GF,Massow O,Lubatschowski H

    更新日期:2009-12-01 00:00:00

  • [Patient Mobility and Journey Distance as Risk Factors for Severe Visual Impairment: Real-Life Data Analysis of Treatment-naïve Patients with nAMD under Intravitreal Aflibercept Therapy].

    abstract:OBJECTIVE:The aim of this study is to describe the effectiveness of aflibercept in treatment-naive patients with neovascular age related macular degeneration (nAMD) and the impact of patients' residential distance to the clinic and patients' mobility on therapy in a pro re nata regime. METHODS:A retrospective dataset ...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:10.1055/a-1008-9357

    authors: Rauchegger T,Angermann R,Meusburger A,Schwab J,Haas G,Kralinger M,Zehetner C

    更新日期:2020-06-01 00:00:00

  • [Hemorrhagic secondary glaucoma after central venous thrombosis].

    abstract::Patients suffering from neovascular glaucoma who had been treated at the First Vienna University Eye Clinic in the years 1966-1979 were analyzed recently in a retrospective study. The present paper concentrates on 144 cases of hemorrhagic secondary glaucoma after central venous thrombosis. It considers only those pati...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-2008-1054882

    authors: Drobec P

    更新日期:1983-08-01 00:00:00

  • [Clinical and histopathological aspects of 113 necrotizing malignant melanomas of the choroid. 1. Clinical and histological features of necrotizing choroidal melanomas].

    abstract:BACKGROUND:Tumor necrosis may reflect a destructive immune reaction. Systematic and statistically significant comparative clinico-histopathologic studies have not yet been reported. PATIENTS AND METHODS:113 necrotizing choroidal melanomas (NCM) recruited from 701 enucleated globes 1967-1988 were resectioned, stained a...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-2008-1034986

    authors: Bialasiewicz AA,Ma JX,Schandig U,von Domarus D,Richard G

    更新日期:1998-11-01 00:00:00

  • [Landolt C and snellen e acuity: differences in strabismus amblyopia?].

    abstract:BACKGROUND:Assessment of visual acuity depends on the optotypes used for measurement. The ability to recognize different optotypes differs even if their critical details appear under the same visual angle. Since optotypes are evaluated on individuals with good visual acuity and without eye disorders, differences in the...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-2005-858613

    authors: Becker R,Gräf M

    更新日期:2006-01-01 00:00:00

  • [Imaging of the Lacrimal Gland and the Lacrimal Drainage System].

    abstract::Die Tränendrüse kann von einer Vielzahl neoplastischer, infektiöser und autoimmunologischer Erkrankungen betroffen sein. Eine radiologische Charakterisierung der Veränderungen kann Hinweise für die differenzialdiagnostische Einordnung liefern. Erkrankungen der ableitenden Tränenwege, insbesondere Tränenwegsverschlüsse...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-0033-1358102

    authors: Pieper CC,Thomas D

    更新日期:2015-03-01 00:00:00

  • [Botulinum Toxin - New Developments in Ophthalmology].

    abstract::Botulinum toxin is recognised as the gold standard for the treatment of essential blepharospasm and hemifacial spasm, which is similar in effect in synkinesis after facial nerve palsy. The injection intervals can be adjusted according to the patients' needs and be shortened for up to six weeks in cases of eyelid cramp...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章,评审

    doi:10.1055/s-0042-122339

    authors: Wabbels B

    更新日期:2018-06-01 00:00:00

  • [Intraocular pressure and primary open-angle glaucoma. Epidemiologic technics in practice].

    abstract::It is the object of this paper to familiarize the ophthalmologist with some modern epidemiological techniques and to present examples of their application to a consideration of the influence of the level of intraocular pressure on the development of the type of visual field loss characteristic of primary open angle gl...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-2008-1054461

    authors: Crick RP,Daubs JG

    更新日期:1984-04-01 00:00:00

  • [Surgical treatment of senile entropion and ectropion of the lower lid (author's transl)].

    abstract::a) Entropion: When developing or discussing a surgical technique one should try to understand how senile entropion develops. On the basis of clinical observation we can develop a suitable surgical technique from our knowledge of atonic (never spastic) entropion. The technique is described and results discussed. b) Ect...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-2008-1057194

    authors: Piffaretti JM

    更新日期:1981-04-01 00:00:00

  • [Preferred techniques of eyelid reconstruction].

    abstract::The trend of lid reconstruction is to use less lid sharing operations. Free tarsoconjunctival or composite grafts in conjunction with covering skin muscle transplants have allowed suitable and cosmetically acceptable methods of full lid repairs. Our preferred surgical techniques are provided. Such methods of reconstru...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章,评审

    doi:10.1055/s-2008-1045933

    authors: Beyer-Machule CK

    更新日期:1991-02-01 00:00:00