Abstract:
:Phthalates (phthalic acid esters) have been widely applied as plasticizers. They are ubiquitous contaminants in soils, thereby posing a threat to human health. In this study, ecotoxicological effects of three typical PAEs (dimethyl phthalate-DMP, di-n-octyl phthalate-DOP and butyl benzyl phthalate-BBP) were investigated. As a biological indicator, earthworms (Eisenia fetida) were exposed to phthalates at various doses (0, 0.1, 1, 10 and 50 mg/kg) for different times (7, 14, 21, and 28 d). We evaluated the effects of phthalates on reactive oxygen species (ROS) generation, antioxidant enzymes (superoxide dismutase-SOD, peroxidase-POD and catalase-CAT) activities, glutathione S-transferase enzyme (GST) activity, malondialdehyde (MDA) content and DNA damage. Results showed that ROS content increased with increasing phthalates, whereas ROS content generally increased and then decreased with exposure time. However, antioxidant enzymes activities in earthworms displayed different trends. The GST activity in high-dose treatment group was significantly activated. For DMP and DOP, lipid peroxidation mainly occurred between 14 and 28 d, while for BBP, it primarily existed after 7 d and then disappeared after 28 d. Besides, comet assay indicated that there was a dose-response relationship between the DNA damage and phthalate dose, following DMP > DOP > BBP. Given their toxicity, it is important to understand the mechanisms associated with their eco-toxicity and to reduce their adverse impacts on the environment.
journal_name
Environ Intjournal_title
Environment internationalauthors
Song P,Gao J,Li X,Zhang C,Zhu L,Wang J,Wang Jdoi
10.1016/j.envint.2019.04.074subject
Has Abstractpub_date
2019-08-01 00:00:00pages
10-17eissn
0160-4120issn
1873-6750pii
S0160-4120(19)31073-6journal_volume
129pub_type
杂志文章abstract::Due to their biological, chemical and physical actions, earthworms can be directly employed within bioremediation strategies to promote biodegradation of organic contaminants. Earthworms have been shown to aerate and bioturbate soils and improve their nutritional status and fertility, which are variables known to limi...
journal_title:Environment international
pub_type: 杂志文章,评审
doi:10.1016/j.envint.2008.02.013
更新日期:2008-10-01 00:00:00
abstract::Few population studies have measured urinary levels of pesticides in individuals with vegan, vegetarian, or organic diets. The objectives of this study were to evaluate whether a vegan/vegetarian diet was associated with increased exposure to organophosphate and carbamate pesticides, and to evaluate the impact of orga...
journal_title:Environment international
pub_type: 杂志文章
doi:10.1016/j.envint.2016.08.027
更新日期:2016-11-01 00:00:00
abstract::This study develops water footprint scenarios for 2050 based on a number of drivers of change: population growth, economic growth, production/trade pattern, consumption pattern (dietary change, bioenergy use) and technological development. The objective the study is to understand the changes in the water footprint (WF...
journal_title:Environment international
pub_type: 杂志文章
doi:10.1016/j.envint.2013.11.019
更新日期:2014-03-01 00:00:00
abstract::The serious fine particle (PM2.5) pollution in China causes millions of premature deaths. Driven by swift economic growth and stringent control policies, air pollutant emissions in China have changed significantly in the last decade, but the change in the source contribution of PM2.5-related health impacts remains unc...
journal_title:Environment international
pub_type: 杂志文章
doi:10.1016/j.envint.2019.105111
更新日期:2019-11-01 00:00:00
abstract::A 2-year field experiment was conducted in an Ochric Aquic Cambosols on a 1-ha field with rotation of winter wheat-summer corn located in Fengqiu County in North China Plain from 1 October 1998 to 30 September 2000 to quantify water balance and evaluate soil water loss by deep drainage and nitrate loss by leaching out...
journal_title:Environment international
pub_type: 杂志文章
doi:10.1016/j.envint.2005.05.038
更新日期:2005-08-01 00:00:00
abstract::It has been reported that microbial reduction of sulfate, nitrite/nitrate and iron/manganese could be coupled with anaerobic oxidation of methane (AOM), which plays a significant role in controlling methane emission from anoxic niches. However, little is known about microbial chromate (Cr(VI)) reduction coupling with ...
journal_title:Environment international
pub_type: 杂志文章
doi:10.1016/j.envint.2019.104926
更新日期:2019-09-01 00:00:00
abstract:BACKGROUND:Early-life carbamate exposure during developmental period has been linked with adverse health effects and attracted attention. METHODS:Three hundred and three children at age of seven were included in the current study. Urinary carbofuranphenol concentrations were measured using gas chromatography-tandem ma...
journal_title:Environment international
pub_type: 杂志文章
doi:10.1016/j.envint.2020.106105
更新日期:2020-12-01 00:00:00
abstract::Greenspace has been increasingly recognized as having numerous health benefits. However, its effects are unknown concerning sudden unexpected death (SUD), commonly referred to as sudden cardiac death, which constitutes a large proportion of mortality in the United States. Because greenspace can promote physical activi...
journal_title:Environment international
pub_type: 杂志文章
doi:10.1016/j.envint.2018.01.021
更新日期:2018-04-01 00:00:00
abstract:BACKGROUND:Exposure to some environmental chemicals is ubiquitous and linked to a variety of adverse outcomes, including children's health. While few studies have assessed the contribution of both male and female exposures to children's health, understanding the patterns of couple's exposure is needed to understand the...
journal_title:Environment international
pub_type: 杂志文章
doi:10.1016/j.envint.2018.11.078
更新日期:2019-02-01 00:00:00
abstract:BACKGROUND:Pesticide exposure during pregnancy is thought to adversely affect fetal growth, which in turn may impact child growth, but results have been inconsistent across studies and few have explored these effects in developing countries. OBJECTIVES:To quantify urinary concentrations of pesticide biomarkers in earl...
journal_title:Environment international
pub_type: 杂志文章
doi:10.1016/j.envint.2019.105243
更新日期:2019-12-01 00:00:00
abstract::Although various pesticides were used globally, the pesticides profiles in human blood serum remain largely unknown. We determined pesticide exposure profiles using solid-phase extraction and gas chromatography tandem with triple quadrupole mass spectrometry in 200 human blood serum samples from the adult population i...
journal_title:Environment international
pub_type: 杂志文章
doi:10.1016/j.envint.2017.03.004
更新日期:2017-05-01 00:00:00
abstract::Early-childhood biomonitoring of persistent organic pollutants (POPs) is challenging due to the logistic and ethical limitations associated with blood sampling. We investigated using faeces as a non-invasive matrix to estimate internal exposure to POPs. The concentrations of selected POPs were measured in matched plas...
journal_title:Environment international
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.envint.2017.06.019
更新日期:2017-10-01 00:00:00
abstract::Sediments used in this study were collected from different depths of eight sites in East China Sea in November 2002. The levels and distribution patterns of the selected organochlorine pesticides (OCPs=p,p'-DDT, o,p'-DDT, p,p'-DDE, p,p'-DDD, alpha-, beta-, gamma- and delta-HCH) in samples were investigated by the tech...
journal_title:Environment international
pub_type: 杂志文章
doi:10.1016/j.envint.2005.05.027
更新日期:2005-08-01 00:00:00
abstract::Xenobiotics from anthropogenic and natural origin enter animal feed and human food as regulated compounds, environmental contaminants or as part of components of the diet. After dietary exposure, a chemical is absorbed and distributed systematically to a range of organs and tissues, metabolised, and excreted. Physiolo...
journal_title:Environment international
pub_type: 杂志文章
doi:10.1016/j.envint.2020.105488
更新日期:2020-03-01 00:00:00
abstract::Inhalation from ambient air and cigarette smoke is a common route of human exposure to polycyclic aromatic hydrocarbons (PAHs). Little information is available regarding hepatotoxicities of inhaled PAHs so for. In this study, we evaluated the toxic effects of intratracheally instilled benzo[a]pyrene (B[a]P) on hepatic...
journal_title:Environment international
pub_type: 杂志文章
doi:10.1016/j.envint.2019.105000
更新日期:2020-01-01 00:00:00
abstract::The biochemical response of wild sticklebacks collected in Autumn 2005 at seven stations in the North of France was studied using a set of complementary biomarkers. Here, data on biotransformation of xenobiotics, oxidative stress exposure and damages, neurotoxicity and endocrine disruption are provided. All the sites ...
journal_title:Environment international
pub_type: 杂志文章
doi:10.1016/j.envint.2007.11.003
更新日期:2008-05-01 00:00:00
abstract::The present work aimed to discuss the enantiomeric occurrence of chiral pharmaceuticals including 5 parent compounds (PCs) metoprolol, propranolol, atenolol, venlafaxine and fluoxetine as well as 6 of their transformation products (TPs) in surface water in Beijing. Among which, 9 out of 11 were detected during the two...
journal_title:Environment international
pub_type: 杂志文章
doi:10.1016/j.envint.2020.105657
更新日期:2020-05-01 00:00:00
abstract::Anaerobic digestion (AD) of organics is a challenging task under high-strength sulfate (SO42-) conditions. The generation of toxic sulfides by SO42--reducing bacteria (SRB) causes low methane (CH4) production. This study investigated the feasibility of alleviating sulfide inhibition and enhancing CH4 production by usi...
journal_title:Environment international
pub_type: 杂志文章
doi:10.1016/j.envint.2020.105503
更新日期:2020-03-01 00:00:00
abstract::The use of pesticides for crop protection may result in the presence of toxic residues in environmental matrices. In the aquatic environment, pesticides might freely dissolve in the water or bind to suspended matter and to the sediments, and might be transferred to the organisms' tissues during bioaccumulation process...
journal_title:Environment international
pub_type: 杂志文章,评审
doi:10.1016/j.envint.2012.12.005
更新日期:2013-03-01 00:00:00
abstract:BACKGROUND:Exposure to perfluoroalkyl substances (PFASs) may disrupt reproductive function in animals and humans. Although PFASs can cross the human placental barrier, few studies evaluated the effects of prenatal PFAS exposure on the fetus' reproductive hormones. OBJECTIVE:To explore the associations of prenatal expo...
journal_title:Environment international
pub_type: 杂志文章
doi:10.1016/j.envint.2016.05.011
更新日期:2016-09-01 00:00:00
abstract::Climate change refers to long-term shifts in weather conditions and patterns of extreme weather events. It may lead to changes in health threat to human beings, multiplying existing health problems. This review examines the scientific evidences on the impact of climate change on human infectious diseases. It identifie...
journal_title:Environment international
pub_type: 杂志文章,评审
doi:10.1016/j.envint.2015.09.007
更新日期:2016-01-01 00:00:00
abstract::Serum lipid levels are major risk factors for cardiovascular disease. In addition to diet, exercise, genetics, age and race, serum concentrations of persistent organic pollutants (POPs) influence concentrations of serum lipids. We investigated associations between fasting concentrations of 35 polychlorinated biphenyl ...
journal_title:Environment international
pub_type: 杂志文章
doi:10.1016/j.envint.2014.07.022
更新日期:2014-12-01 00:00:00
abstract::Environmental health hazard assessments are routinely relied upon for public health decision-making. The evidence base used in these assessments is typically developed from a collection of diverse sources of information of varying quality. It is critical that literature-based evaluations consider the credibility of in...
journal_title:Environment international
pub_type: 杂志文章
doi:10.1016/j.envint.2016.01.005
更新日期:2016-07-01 00:00:00
abstract::Phytoestrogens (PEs) are naturally occurring chemical constituents of certain plants. The internal PE exposures, mainly from diet, vary among different populations and in different regions due to various eating habits. To investigate the potential relationship between urinary PE levels and idiopathic male infertility ...
journal_title:Environment international
pub_type: 杂志文章
doi:10.1016/j.envint.2013.06.009
更新日期:2013-09-01 00:00:00
abstract::Polychlorinated biphenyls (PCBs) are infamous industry by-products or additives, and increasing evidences demonstrated that their exposure is associate with adverse effects on human health. Liver, as the dominate site for xenobiotic metabolism, is apt to be the primary target of PCBs insult. Although PCBs' hepatic tox...
journal_title:Environment international
pub_type: 杂志文章
doi:10.1016/j.envint.2020.105701
更新日期:2020-06-01 00:00:00
abstract::Both dietary and non-dietary pathways contribute to metal exposure in residents living near mining-impacted areas. In this study, bioavailability-based metal intake estimation coupled with stable Pb isotope ratio fingerprinting technique were used to discern dietary (i.e., rice consumption) and non-dietary (i.e., hous...
journal_title:Environment international
pub_type: 杂志文章
doi:10.1016/j.envint.2018.08.023
更新日期:2018-11-01 00:00:00
abstract::There are unique challenges in estimating dose-response with chemicals that are associated with multiple health outcomes and numerous studies. Some studies are more suitable than others for quantitative dose-response analyses. For such chemicals, an efficient method of screening studies and endpoints to identify suita...
journal_title:Environment international
pub_type: 杂志文章
doi:10.1016/j.envint.2020.105986
更新日期:2020-11-01 00:00:00
abstract::Globally, many of our urban agriculture sites (UAS) contain high levels of lead (Pb), a contaminant of toxicological concern to humans. To improve the derivation of soil assessment criteria at UAS, and avoid inappropriate closure of these valuable community spaces, we sampled nearly 280 paired soil and crop samples ac...
journal_title:Environment international
pub_type: 杂志文章
doi:10.1016/j.envint.2018.10.054
更新日期:2019-01-01 00:00:00
abstract::Mercury contamination in soil, water and air is associated with potential toxicity to humans and ecosystems. Industrial activities such as coal combustion have led to increased mercury (Hg) concentrations in different environmental media. This review critically evaluates recent developments in technological approaches...
journal_title:Environment international
pub_type: 杂志文章,评审
doi:10.1016/j.envint.2019.105281
更新日期:2020-01-01 00:00:00
abstract:BACKGROUND:Ambient fine particulate matter (PM2.5) pollution is currently a serious environmental problem in China, but evidence of health effects with higher resolution and spatial coverage is insufficient. OBJECTIVE:This study aims to provide a better overall understanding of long-term mortality effects of PM2.5 pol...
journal_title:Environment international
pub_type: 杂志文章
doi:10.1016/j.envint.2017.10.015
更新日期:2018-01-01 00:00:00