Abstract：
OBJECTIVE:To evaluate the effects of household use of cleaning products during pregnancy on infant wheezing and lower respiratory tract infections (LRTI). METHODS:In four prospective Spanish birth cohorts (n = 2,292), pregnant women reported the use of household cleaning products. When infants were 12-18 months old, current cleaning product use and infant's wheezing and LRTI were reported. Cohort-specific associations between the use of specific products and respiratory outcomes were evaluated using multivariable regression analyses and estimates were combined using random-effects meta-analyses. RESULTS:The period prevalence of LRTI was higher when sprays (combined odds ratio (OR) = 1.29; 95 % confidence interval (CI) 1.04-1.59) or air fresheners (OR = 1.29; CI 1.03-1.63) were used during pregnancy. The odds of wheezing increased with spray (OR = 1.37; CI 1.10-1.69) and solvent (OR = 1.30; CI 1.03-1.62) use. The associations between spray and air freshener use during pregnancy and both outcomes remained apparent when these products were not used after pregnancy. Nevertheless, the estimates were higher when post-natal exposure was included. CONCLUSION:The use of cleaning sprays, air fresheners and solvents during pregnancy may increase the risk of wheezing and infections in the offspring.
journal_name
Int J Public Healthjournal_title
International journal of public healthauthors
Casas L,Zock JP,Carsin AE,Fernandez-Somoano A,Esplugues A,Santa-Marina L,Tardón A,Ballester F,Basterrechea M,Sunyer Jdoi
10.1007/s00038-012-0417-2subject
Has Abstractpub_date
2013-10-01 00:00:00pages
757-64issue
5eissn
1661-8556issn
1661-8564journal_volume
58pub_type
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