Abstract:
:In a previous paper we presented a theoretical framework to describe tissue growth in confined geometries based on the work of Ambrosi and Guillou [Ambrosi D, Guillou A. Growth and dissipation in biological tissues. Cont Mech Thermodyn 2007;19:245-51]. A thermodynamically consistent eigenstrain rate for growth was derived using the concept of configurational forces and used to investigate growth in holes of cylindrical geometries. Tissue growing from concave surfaces can be described by a model based on this theory. However, an apparently asymmetric behaviour between growth from convex and concave surfaces has been observed experimentally, but is not predicted by this model. This contradiction is likely to be due to the presence of contractile tensile stresses produced by cells near the tissue surface. In this contribution we extend the model in order to couple tissue growth to the presence of a surface stress. This refined growth model is solved for two geometries, within a cylindrical hole and on the outer surface of a cylinder, thus demonstrating how surface stress may indeed inhibit growth on convex substrates.
journal_name
Acta Biomaterjournal_title
Acta biomaterialiaauthors
Gamsjäger E,Bidan CM,Fischer FD,Fratzl P,Dunlop JWdoi
10.1016/j.actbio.2012.10.020subject
Has Abstractpub_date
2013-03-01 00:00:00pages
5531-43issue
3eissn
1742-7061issn
1878-7568pii
S1742-7061(12)00497-7journal_volume
9pub_type
杂志文章abstract::Because of the increasing incidence of coronary artery disease, the importance of cardiovascular stents has continuously increased as a treatment of this disease. Biodegradable scaffolds fabricated from polymers and metals have emerged as promising materials for vascular stents because of their biodegradability. Altho...
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journal_title:Acta biomaterialia
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pub_type: 杂志文章
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更新日期:2005-09-01 00:00:00
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journal_title:Acta biomaterialia
pub_type: 杂志文章
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更新日期:2013-12-01 00:00:00
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journal_title:Acta biomaterialia
pub_type: 杂志文章
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更新日期:2012-12-01 00:00:00
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pub_type: 杂志文章
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更新日期:2010-09-01 00:00:00
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journal_title:Acta biomaterialia
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journal_title:Acta biomaterialia
pub_type: 杂志文章
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更新日期:2011-09-01 00:00:00
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journal_title:Acta biomaterialia
pub_type: 杂志文章
doi:10.1016/j.actbio.2010.10.013
更新日期:2011-03-01 00:00:00
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journal_title:Acta biomaterialia
pub_type: 杂志文章
doi:10.1016/j.actbio.2009.01.004
更新日期:2009-06-01 00:00:00
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doi:10.1016/j.actbio.2012.03.028
更新日期:2012-07-01 00:00:00
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journal_title:Acta biomaterialia
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更新日期:2018-06-01 00:00:00
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journal_title:Acta biomaterialia
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更新日期:2016-10-15 00:00:00
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journal_title:Acta biomaterialia
pub_type: 杂志文章
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更新日期:2014-12-01 00:00:00
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更新日期:2016-11-01 00:00:00
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journal_title:Acta biomaterialia
pub_type: 杂志文章
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更新日期:2007-11-01 00:00:00
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journal_title:Acta biomaterialia
pub_type: 杂志文章
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更新日期:2018-01-15 00:00:00
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journal_title:Acta biomaterialia
pub_type: 评论,杂志文章,评审
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更新日期:2016-05-01 00:00:00
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journal_title:Acta biomaterialia
pub_type: 杂志文章
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更新日期:2018-07-15 00:00:00
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journal_title:Acta biomaterialia
pub_type: 杂志文章
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