Abstract：
BACKGROUND:Blood gas analysis and blood lactate measurement have important roles in patient management. Point-of-care (POC) testing simplifies and provides rapid blood gas and lactate measurements. This study aimed to compare pH, pCO2 , pO2 , and lactate measurements between a POC device and a benchtop blood gas analyzer typically used in a hospital central laboratory, and to evaluate the inter-device variability of the POC device. METHODS:A cross-sectional study was conducted with a sample size of 100. Each sample was measured for pH, pCO2 , pO2 , and lactate using a Nova pHOx plus L® benchtop blood gas analyzer in the central laboratory and an i-STAT® handheld POC device. The results of both devices were compared using Pearson or Spearman correlation coefficients and Bland-Altman tests. Testing of the inter-device variability was done by using three different i-STAT® devices, and the results were compared statistically. RESULTS:Strong correlations were observed for all test results. In Bland-Altman analysis, ≥95% of the results were within the limits of agreement, with the exception of lactate, which had only 93%. The results that were beyond the limits were primarily lactate levels >8 mmol/L. Biases between the benchtop analyzer and the i-STAT® were not clinically significant, except pH. No significant inter-device variability was observed between the i-STAT® analyzers. CONCLUSION:This comparison study of pH, pCO2 , pO2 , and lactate measurements between Nova pHOx plus L® and i-STAT® analyzers showed good agreement. However, lactate measurement results >8 mmol/L on the i-STAT® analyzer should be interpreted with caution.
journal_name
J Clin Lab Analjournal_title
Journal of clinical laboratory analysisauthors
Indrasari ND,Wonohutomo JP,Sukartini Ndoi
10.1002/jcla.22885subject
Has Abstractpub_date
2019-06-01 00:00:00pages
e22885issue
5eissn
0887-8013issn
1098-2825journal_volume
33pub_type
杂志文章abstract：:The Venereal Disease Research Laboratory (VDRL) test has long been considered the best serological test for the diagnosis of neurosyphilis. The goal of this study was to find out if the Rapid Plasma Reagin (RPR) could be an alternative to the VDRL. Cerebrospinal fluid (CSF) and sera samples from patients in the follow...
journal_title：Journal of clinical laboratory analysis
pub_type： 杂志文章
doi：10.1002/jcla.20254
更新日期：2008-01-01 00:00:00
abstract：:We report nine donations with ABO inconsistency in reverse typing caused by partly or entirely missing antibodies. A and B antigens and antibodies were examined by serological blood typing, and ABO deoxyribonucleic acid (DNA) analyses were performed by sequence-specific priming and sequencing. A B101 allele was demons...
journal_title：Journal of clinical laboratory analysis
pub_type： 杂志文章
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abstract：:The immune complex transfer enzyme immunoassay for antibody IgG to HIV-1 gp41 antigen was developed using two synthetic peptides. An aliquot (10 microl) of serum samples from HIV-1 seropositive subjects was incubated simultaneously with 2,4-dinitrophenyl-bovine serum albumin-synthetic HIV-1 gp41 peptide conjugates and...
journal_title：Journal of clinical laboratory analysis
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journal_title：Journal of clinical laboratory analysis
pub_type： 杂志文章,meta分析
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journal_title：Journal of clinical laboratory analysis
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doi：10.1002/jcla.21593
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doi：10.1002/jcla.10038
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journal_title：Journal of clinical laboratory analysis
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journal_title：Journal of clinical laboratory analysis
pub_type： 杂志文章
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journal_title：Journal of clinical laboratory analysis
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pub_type： 杂志文章
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pub_type： 杂志文章
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journal_title：Journal of clinical laboratory analysis
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doi：10.1002/(SICI)1098-2825(1996)10:6<403::AID-JCLA15>
更新日期：1996-01-01 00:00:00
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doi：10.1002/(sici)1098-2825(1997)11:3<129::aid-jcla2>3
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journal_title：Journal of clinical laboratory analysis
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doi：
更新日期：1997-01-01 00:00:00
