Abstract:
:G protein-coupled receptors (GPCRs) are key signaling proteins that regulate how cells interact with their environment. Traditional signaling cascades involving GPCRs have been well described and are well established and very important clinical targets. With the development of more recent technologies, hints about the involvement of GPCRs in fundamental cell biological processes are beginning to emerge. In this review, we give a basic introduction to GPCR signaling and highlight some less well described roles of GPCRs, including in cell division and membrane trafficking, which may occur through canonical and non-canonical signaling pathways.
journal_name
Mol Biosystjournal_title
Molecular bioSystemsauthors
Zhang X,Eggert USdoi
10.1039/c2mb25429hsubject
Has Abstractpub_date
2013-04-05 00:00:00pages
586-95issue
4eissn
1742-206Xissn
1742-2051journal_volume
9pub_type
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