Abstract：
:Circulating tumor DNA (ctDNA) holds great promise as a noninvasive diagnostic tool to guide treatment for patients with lung cancer. Two studies by Phallen and colleagues and Anagnostou and colleagues correlated sensitive measures of ctDNA with clinical responses to tyrosine kinase inhibitors (TKI) and immune checkpoint inhibitors, respectively, in patients with non-small cell lung cancer (NSCLC). Together, these studies further highlight the potential clinical utility of serial ctDNA monitoring in patients with NSCLC undergoing treatment with both targeted therapies and immunotherapies.See related articles by Phallen et al., p. 1204, and Anagnostou et al., p. 1214.
journal_name
Cancer Resjournal_title
Cancer researchauthors
Zou T,Meyerson Mdoi
10.1158/0008-5472.CAN-19-0231subject
Has Abstractpub_date
2019-03-15 00:00:00pages
1038-1040issue
6eissn
0008-5472issn
1538-7445pii
79/6/1038journal_volume
79pub_type
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