Abstract：
:The pancreatic carcinogen N-nitrosobis(2-oxopropyl)-amine was administered to Syrian golden hamsters after cholecystoduodenostomy and choledochostomy to investigate a possible bile reflux mechanism as a factor in pancreatic carcinogenesis. The induced lesions were similar in morphology, multiplicity, and distribution to those of animals in other studies without surgery. Hence the findings contraindicate the importance of biliary reflux in pancreatic tumor induction. Other possible mechanisms are discussed.
journal_name
Cancer Resjournal_title
Cancer researchauthors
Pour P,Donnelly Tsubject
Has Abstractpub_date
1978-07-01 00:00:00pages
2048-51issue
7eissn
0008-5472issn
1538-7445journal_volume
38pub_type
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