Mucinous Tubular and Spindle Cell Carcinoma: A Review of Histopathology and Clinical and Prognostic Implications.

Abstract:

:Mucinous tubular and spindle cell carcinomas are rare kidney tumors with generally indolent behavior. As the name suggests, classic histomorphology reveals bland spindle cells, tubules, and mucinous stroma. Uncommon histologic features include mucin-poor stroma, high nuclear grade, cellular pleomorphism, and presence of necrosis. Rare cases can show aggressive growth and distant metastasis. Mucinous tubular and spindle cell carcinoma has characteristic chromosomal abnormalities and the molecular signature remains the same, irrespective of the varied histomorphology.

journal_name

Arch Pathol Lab Med

authors

Nathany S,Monappa V

doi

10.5858/arpa.2017-0506-RS

subject

Has Abstract

pub_date

2020-01-01 00:00:00

pages

115-118

issue

1

eissn

0003-9985

issn

1543-2165

journal_volume

144

pub_type

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