A method for the reconstruction of unknown non-monotonic growth functions in the chemostat.

abstract：:Harvesting technology has a significant influence on the microalgal biomass industry. This study develops a buoy-bead flotation method and analyzes the factors impacting flotation. Experimental results show that adding sodium borosilicate as an alternative microsphere material can result in 58.5% harvesting efficiency...

journal_title：Bioprocess and biosystems engineering

authors： Wen H,Zou X,Xu K,Shen Z,Ren X,Li Y

更新日期：2019-03-01 00:00:00

abstract：:A metabolic network was constructed for the Acremonium chrysogenum cultivation fed with soybean oil. Metabolic flux analysis indicated that the shift from exponential growth to rapid cephalosporin C (CPC) formation was accompanied by 1.63- and 5-fold carbon flux enlargement in TCA cycle and glyoxylate by-pass, respect...

journal_title：Bioprocess and biosystems engineering

authors： Li J,Yang Y,Chu J,Huang M,Li L,Zhang X,Wang Y,Zhuang Y,Zhang S

更新日期：2010-11-01 00:00:00

abstract：:A serine alkaline protease from a newly isolated alkaliphilic Bacillus altitudinis GVC11 was purified and characterized. The enzyme was purified to homogeneity by acetone precipitation, DEAE-cellulose anion exchange chromatography with 7.03-fold increase in specific activity and 15.25% recovery. The molecular weight o...

journal_title：Bioprocess and biosystems engineering

authors： Vijay Kumar E,Srijana M,Kiran Kumar K,Harikrishna N,Reddy G

更新日期：2011-05-01 00:00:00

abstract：:Chemical modification of lysine residues in Candida rugosa lipase (CRL) was carried out using five different functional ionic liquids, and about 15.4-25.0 % of the primary amino groups of lysine were modified. Enzymatic properties of the native and modified CRLs were investigated in olive oil hydrolysis reaction. Impr...

journal_title：Bioprocess and biosystems engineering

authors： Hu Y,Yang J,Jia R,Ding Y,Li S,Huang H

更新日期：2014-08-01 00:00:00

abstract：:A new protein assay system for the antigen-antibody interaction was developed by immobilization of carcinoembryonic antibody (anti-CEA) onto magnetic-core/gold-shell nanoparticles-functionalized biomimetic interface on multiporous polythionine modified magnetic carbon paste electrodes (MCPE). Differential pulse voltam...

journal_title：Bioprocess and biosystems engineering

authors： Tang D,Yuan R,Chai Y

更新日期：2008-02-01 00:00:00

abstract：:The previous works on simulated broths are continued and developed for Propionibacterium shermanii broths. The obtained results indicated the considerable increase of kLa in presence of n-dodecane as oxygen-vector and the existence of a certain value of hydrocarbon concentration that corresponds to the maximum mass tr...

journal_title：Bioprocess and biosystems engineering

authors： Galaction AI,Cascaval D,Turnea M,Folescu E

更新日期：2005-07-01 00:00:00

abstract：:Light and bacteria can be used in combination to enhance secondary metabolite production during fermentation. Red yeast rice powder (RYRP) was inoculated with Bacillus subtilis (B2) isolated from freshwater seafood and incubated under light-emitting diodes (LEDs) of different colors (blue, green, red, white), fluoresc...

journal_title：Bioprocess and biosystems engineering

authors： Elumalai P,Park YJ,Cho M,Shea PJ,Oh BT

更新日期：2019-04-01 00:00:00

abstract：:A total monosaccharide concentration of 37.8 g/L and 85.9% conversion from total fermentable monosaccharides of 44.0 g/L from 110 g dw/L Eucheuma denticulatum slurry were obtained by thermal acid hydrolysis and enzymatic saccharification. Subsequent adsorption treatment to remove 5-hydroxymethylfurfural (5-HMF) using ...

journal_title：Bioprocess and biosystems engineering

authors： Ra CH,Kim MJ,Jeong GT,Kim SK

更新日期：2017-03-01 00:00:00

abstract：:Sodium dodecyl sulfate (SDS) is a widely used anionic surfactant, which finds its way to the receiving water body due to the incapability of conventional wastewater treatment systems to completely remove it. A hybrid treatment system consisting of upflow microbial fuel cell (MFC) with titanium dioxide (TiO2) as a phot...

journal_title：Bioprocess and biosystems engineering

authors： Sathe SM,Bhowmick GD,Dubey BK,Ghangrekar MM

更新日期：2020-11-01 00:00:00

abstract：:Twenty-nine actinobacterial strains were isolated from marine sponge Spongia officinalis and screened for antagonistic activity against various bacterial and fungal pathogens. The active antibiotic producer MAPS15 was identified as Streptomyces sp. using 16S rRNA phylogenetic analysis. The critical control factors wer...

journal_title：Bioprocess and biosystems engineering

authors： Sathiyanarayanan G,Gandhimathi R,Sabarathnam B,Seghal Kiran G,Selvin J

更新日期：2014-03-01 00:00:00

abstract：:A solvent-free biocatalytic process for the synthesis of high quality cetyl laurate, myristate, palmitate and stearate has been optimized. This enzymatic procedure follows the fundamental principles of the Green Chemistry and lead to sustainable products, which can be labeled as natural and conform to the principal re...

journal_title：Bioprocess and biosystems engineering

authors： Serrano-Arnaldos M,Máximo-Martín MF,Montiel-Morte MC,Ortega-Requena S,Gómez-Gómez E,Bastida-Rodríguez J

更新日期：2016-04-01 00:00:00

abstract：:A rapid method for designing integrated bioprocesses, using a combination of a windows of operation and a Pareto optimisation approach, is described in this paper. Within bioprocesses, multiple objectives are common, and achieving a satisfactory trade-off amongst the design objectives is crucial. Conventional optimisa...

journal_title：Bioprocess and biosystems engineering

authors： Zhou YH,Titchener-Hooker NJ

更新日期：2003-07-01 00:00:00

abstract：:One of the problems to be solved in attaining the full potentials of hematopoietic stem cell (HSC) applications is the limited availability of the cells. Growing HSCs in a bioreactor offers an alternative solution to this problem. Besides, it also offers the advantages of eliminating labour intensive process as well a...

journal_title：Bioprocess and biosystems engineering

authors： Kresnowati MT,Forde GM,Chen XD

更新日期：2011-01-01 00:00:00

abstract：:During ribonucleic acid fermentation, the fermentative processes were researched at pH controlled at 4.0 and under natural conditions. Unstructured models in a 50-L airlift fermentor were established for batch RNA production at pH 4.0 using the Verhulst equation for microbial growth, the Luedeking-Piret equation for p...

journal_title：Bioprocess and biosystems engineering

authors： Li B,Chen X,Ren H,Li L,Xiong J,Bai J,Chen Y,Wu J,Ying H

更新日期：2012-03-01 00:00:00

abstract：:Broken rice, pretreated by enzymatic extrusion liquefaction, was used to produce Chinese rice wine by simultaneous saccharification and fermentation (SSF) process in this study. The study compared the novel process and traditional process for Chinese rice wine fermentation utilizing broken rice and head rice, respecti...

journal_title：Bioprocess and biosystems engineering

authors： Li H,Jiao A,Xu X,Wu C,Wei B,Hu X,Jin Z,Tian Y

更新日期：2013-08-01 00:00:00

abstract：:Understanding process parameter interactions and their effects on mammalian cell cultivations is an essential requirement for robust process scale-up. Furthermore, knowledge of the relationship between the process parameters and the product critical quality attributes (CQAs) is necessary to satisfy quality by design g...

journal_title：Bioprocess and biosystems engineering

authors： Brunner M,Fricke J,Kroll P,Herwig C

更新日期：2017-02-01 00:00:00

abstract：:An optimized repeated-fed-batch fermentation process for the synthesis of dihydroxyacetone (DHA) from glycerol utilizing Gluconobacter oxydans is presented. Cleaning, sterilization, and inoculation procedures could be reduced significantly compared to the conventional fed-batch process. A stringent requirement was tha...

journal_title：Bioprocess and biosystems engineering

authors： Hekmat D,Bauer R,Fricke J

更新日期：2003-12-01 00:00:00

abstract：:Microalgal carotenoids are attractive health ingredients, but their production should be optimized to improve cost-effectiveness. Understanding cellular physiology centered on carotenoid synthesis is the prerequisite for this work. Therefore, systematic correlation analyses were conducted among chlorophyll, carotenoid...

journal_title：Bioprocess and biosystems engineering

authors： Song HG,Byeon SY,Chung GY,Jung SM,Choi JI,Shin HS

更新日期：2018-09-01 00:00:00

abstract：:Lactococcus lactis spp. lactis and Lactococcus lactis spp. cremoris are widely used in the manufacture of fermented milk. These strains were compared for production of Dipeptidyl Peptidase IV (DPP IV) enzyme in terms of enzyme activity, specific growth rates and productivity. Lactococcus lactis spp. lactis was produce...

journal_title：Bioprocess and biosystems engineering

authors： Ustün O,Ongen G

更新日期：2012-10-01 00:00:00

abstract：:Porphyridium cruentum is one of the most valued microalgae species able to produce both pigments and exopolysaccharides. Conventional liquid suspended cultivation in ponds and photobioreactors show its disadvantages in lower cultivation efficiency and higher stirring power consumption due to the high viscosity of the ...

journal_title：Bioprocess and biosystems engineering

authors： Lutzu GA,Zhang L,Zhang Z,Liu T

更新日期：2017-01-01 00:00:00

abstract：:For the construction of an efficient copper waste treatment system, a cell surface display strategy was employed. The copper adsorption ability of recombinant bacterial strains displaying three different copper binding peptides were evaluated in LB Luria-Bertani medium (LB), artificial wastewater, and copper phthalocy...

journal_title：Bioprocess and biosystems engineering

authors： Maruthamuthu MK,Nadarajan SP,Ganesh I,Ravikumar S,Yun H,Yoo IK,Hong SH

更新日期：2015-11-01 00:00:00

abstract：:This work studies the sequential execution of dilute sulfuric acid (DAP) (0.1-0.75 %, v/v) and dilute sodium hydroxide (AKP) (0.25-3 %, w/v) [i.e., DAP followed by AKP (DAP+AKP) and vice versa (AKP+DAP)] at low temperatures (<121 °C) and short reaction times (5-60 min) for maximizing sugar recovery in the enzymatic hy...

journal_title：Bioprocess and biosystems engineering

authors： Sanchez A,Gil JC,Rojas-Rejón OA,de Alba AP,Medina A,Flores R,Puente R

更新日期：2015-06-01 00:00:00

abstract：:High amounts of outer membrane (OM) components were released in glucose-limited fed-batch (GLFB) cultures at 37 degrees C at specific growth rates approaching 0.05 h(-1). Endotoxin analyses from a 20 degrees C GLFB culture gave similar results. An alternative fermentation technique, the temperature-limited fed-batch (...

journal_title：Bioprocess and biosystems engineering

authors： Svensson M,Han L,Silfversparre G,Häggström L,Enfors SO

更新日期：2005-04-01 00:00:00

abstract：:Recently, several studies have been published on the application of plasmid DNA (pDNA) in gene therapy and vaccine production. The bioprocess to obtain pDNA involves the steps of fermentation, primary recovery, secondary recovery and final purification. The pDNA primary recovery, which is the key step to the rest of t...

journal_title：Bioprocess and biosystems engineering

authors： Padilla-Zamudio A,Guerrero-Germán P,Tejeda-Mansir A

更新日期：2015-06-01 00:00:00

abstract：:A data-driven model is presented that can serve two important purposes. First, the specific growth rate and the specific product formation rate are determined as a function of time and thus the dependency of the specific product formation rate from the specific biomass growth rate. The results appear in form of traine...

journal_title：Bioprocess and biosystems engineering

authors： Gnoth S,Jenzsch M,Simutis R,Lübbert A

更新日期：2008-01-01 00:00:00

abstract：:(R)-2-hydroxy-4-phenylbutyric acid (R-HPBA) is a valuable intermediate for the synthesis of angiotensin-converting enzyme inhibitors. The asymmetric reduction of 2-oxo-4-phenylbutyric acid (OPBA) by oxidoreductases is an efficient approach for its synthesis. Here, we report a novel biocatalytic approach for asymmetric...

journal_title：Bioprocess and biosystems engineering

authors： Wang X,Yu Z,Tang J,Yi D,Chen S

更新日期：2018-09-01 00:00:00

abstract：:Erythromycin A is an important antibiotic. A chemically defined synthetic medium for erythromycin production was systematically optimized in this study. A high-throughput method was employed to reduce the number of components and optimize the concentration of each component. After two round single composition deletion...

journal_title：Bioprocess and biosystems engineering

authors： Hong M,Liao J,Chu J

更新日期：2018-10-01 00:00:00

abstract：:The optimization of operating conditions for cellulose hydrolysis was systemically undertaken using an ultra-scaled down membrane bioreactor based on the parameter scanning ultrafiltration apparatus. The bioconversion of cellulose saccharification was carried out with freely suspended cellulase from Aspergillus niger ...

journal_title：Bioprocess and biosystems engineering

authors： Liu J,Lu J,Cui Z

更新日期：2011-06-01 00:00:00

abstract：:ε-Poly-L-lysine (ε-PL) is produced by Streptomyces as a secondary metabolite with wide industrial applications, but its production still needs to be further enhanced. Environmental stress is an important approach for the promotion of secondary metabolites production by Streptomyces. In this study, the effect of acidic...

journal_title：Bioprocess and biosystems engineering

authors： Ren XD,Chen XS,Zeng X,Wang L,Tang L,Mao ZG

更新日期：2015-06-01 00:00:00

abstract：:The yeast Rhodotorula glutinis was examined for its ability to remove Pb(2+) from aqueous solution. Within 10 min of contact, Pb(2+) sorption reached nearly 80% of the total Pb(2+) sorption. The optimum initial pH value for removal of Pb(2+ )was 4.5-5.0. The percentage sorption increased steeply with the biomass conce...

journal_title：Bioprocess and biosystems engineering

authors： Cho DH,Kim EY

更新日期：2003-03-01 00:00:00