Abstract：
BACKGROUND:To investigate prognostic factors for complete remission in type 2 diabetes mellitus (T2DM) patients who underwent gastric bypass (GBP) and to establish a prognostic model for risk stratification. METHODS:We evaluated the baseline clinical features of patients with T2DM who received at Beijing Tian Tan Hospital from April 2012 to December 2015. Complete remission of T2DM was defined as meeting the following criteria: HbA1c < 6.5%, fasting plasma glucose (FPG) < 100 mg/dL, and absence of hypoglycemic drugs for 1 year following GBP. RESULTS:A total of 101 patients were enrolled in our study, and the complete remission rate of T2DM was 70.3% (71/101). Compared with patients with incomplete remission, patients with complete remission of T2DM had higher C-peptide levels, lower HbA1c, shorter disease duration, better β cell function, and an absence of insulin therapy. HbA1c level, fasting C-peptide, duration of T2DM, and history of medical therapy were important prognostic factors for complete remission of T2DM (P = 0.001, 0.002, 0.01, 0.028, respectively). Patients with HbA1c lower than 7.5%, a history of T2DM shorter than 9.5 years, fasting C-peptide higher than 1.2 ng/mL, and absence of insulin therapy before GBP achieved a higher complete remission rate of T2DM after GBP (AUC of the model was 0.825, 95% CI, 0.741-0.910; P = 0.001). CONCLUSIONS:The duration of T2DM, history of medical therapy, and levels of HbA1c and fasting C-peptide are independent predictors for the prognosis of T2DM patients undergoing GBP. Patients with HbA1c lower than 7.5%, a history of T2DM shorter than 9.5 years, a fasting C-peptide higher than 1.2 ng/mL, and an absence of insulin therapy may have a higher complete remission rate of T2DM after GBP.
journal_name
Obes Surgjournal_title
Obesity surgeryauthors
Yan W,Bai R,Li Y,Xu J,Zhong Z,Xing Y,Yan M,Lin Y,Song Mdoi
10.1007/s11695-019-03783-xsubject
Has Abstractpub_date
2019-06-01 00:00:00pages
1867-1873issue
6eissn
0960-8923issn
1708-0428pii
10.1007/s11695-019-03783-xjournal_volume
29pub_type
杂志文章相关文献
OBESITY SURGERY文献大全abstract：BACKGROUND:It is unclear whether specific gut microbiota is associated with remission of type 2 diabetes (T2D) after distinct types of bariatric surgery. AIMS:The aim of this study is to examine gut microbiota changes after laparoscopic Roux-en-Y gastric bypass (RYGB) or sleeve gastrectomy (SG) surgery in obese patien...
journal_title：Obesity surgery
pub_type： 杂志文章,随机对照试验
doi：10.1007/s11695-016-2399-2
更新日期：2017-04-01 00:00:00
abstract：BACKGROUND:Between 2 and 8 weeks before surgery, most bariatric surgery groups establish strict dietary treatments with a total caloric intake of less than 1,000 kcal/day in order to maximize weight loss during this period of time. METHODS:A prospective randomized clinical trial of all the patients undergoing laparosc...
journal_title：Obesity surgery
pub_type： 杂志文章,随机对照试验
doi：10.1007/s11695-015-1880-7
更新日期：2016-06-01 00:00:00
abstract：BACKGROUND:To create a bond between the technique proposed and the patient, flexibility and adaptability are indispensable. Thus, we devised the functional gastric bypass, which can be activated and deactivated by inflating or deflating the Lap-Band. METHODS:The Lap-Band was positioned according to the standard techni...
journal_title：Obesity surgery
pub_type： 杂志文章
doi：10.1381/096089202320995754
更新日期：2002-12-01 00:00:00
abstract：AIM:Our primary aim was to determine whether non-attendance at pre-operative clinics were associated with non-attendance at post-operative clinics and its influence on weight loss. We also sought to examine the relationship between gender, ethnicity and post-operative clinic attendance with respect to weight loss post-...
journal_title：Obesity surgery
pub_type： 杂志文章
doi：10.1007/s11695-019-03843-2
更新日期：2019-07-01 00:00:00
abstract：BACKGROUND:The rise of bariatric surgery has lead to an increasing number of reoperations for failed bariatric procedures. The reasons and types of these operations are varied in nature and remain to be defined. METHODS:A retrospective review of a prospectively collected database was conducted to identify patients who...
journal_title：Obesity surgery
pub_type： 杂志文章
doi：10.1007/s11695-010-0234-8
更新日期：2011-08-01 00:00:00
abstract：BACKGROUND:Among the various operations used for surgical treatment of morbid obesity, adjustable silicone gastric banding (ASGB) is the least invasive. Many good results have been described. During extended follow-up, however, serious complications may occur. We briefly describe our results with ASGB and will focus on...
journal_title：Obesity surgery
pub_type： 杂志文章
doi：10.1381/09608920060674067
更新日期：2000-02-01 00:00:00
abstract：BACKGROUND:Hepatitis C virus (HCV) is an important cause of liver cirrhosis and its complications. The safety and efficacy of bariatric surgery in patients with HCV infection is not clear. METHODS:Charts were reviewed to identify patients with HCV infection before bariatric surgery. Bariatric surgical patients with no...
journal_title：Obesity surgery
pub_type： 杂志文章
doi：10.1007/s11695-018-3615-z
更新日期：2019-03-01 00:00:00
abstract：:The relationship between bariatric surgery and gastric cancer is conjectural. We present a 52-year-old woman with BMI 45 operated initially by a Lap-Band procedure complicated by gastric wall erosion of the band 9 months later. She was re-operated and the band was removed. She subsequently underwent a Roux-en-Y gastri...
journal_title：Obesity surgery
pub_type： 杂志文章
doi：10.1381/0960892055002383
更新日期：2005-09-01 00:00:00
abstract：OBJECTIVE:To determine possible preoperative predictors for obtaining clinically meaningful weight loss with gastric electrical stimulation (GES) using the "Three-Factor Eating Questionnaire" (TFEQ) as well as epidemiological data. METHODS:Ninety-seven obese participants in a prospective multicenter randomized study c...
journal_title：Obesity surgery
pub_type： 杂志文章
doi：10.1007/s11695-016-2495-3
更新日期：2017-06-01 00:00:00
abstract：BACKGROUND:Fatty acids (FAs) and adipokines such as adiponectin or interleukin-6 (IL-6) are known to modulate inflammation and the development of metabolic syndrome. Whether FA composition assessed in plasma triacylglycerols (TAGs), phospholipids (PLs) and non-esterified fatty acids (NEFAs) and adipose tissue (AT) PLs ...
journal_title：Obesity surgery
pub_type： 杂志文章
doi：10.1007/s11695-012-0633-0
更新日期：2012-06-01 00:00:00
abstract：:The remarkable control of diabetes by the gastric bypass remains to be explained. Although it may be totally due to the weight loss Induced by the operation, it is likely that the detour of the hormonally active foregut plays a role as well. This keynote address explores the pathophysiology of non-insulin-dependent di...
journal_title：Obesity surgery
pub_type： 杂志文章
doi：10.1381/096089292765559891
更新日期：1992-11-01 00:00:00
abstract：:It has been suggested that a shift in food choices leading to a diet with a lower energy density plays an important role in successful weight loss after Roux-en-Y gastric bypass (RYGB) surgery. A decreased hedonic drive to consume highly palatable foods may explain these changes in eating behavior. Here, we review the...
journal_title：Obesity surgery
pub_type： 杂志文章,评审
doi：10.1007/s11695-016-2217-x
更新日期：2016-08-01 00:00:00
abstract：INTRODUCTION:Different factors, such as age, gender, preoperative weight but also the patient's motivation, are known to impact outcomes after Roux-en-Y gastric bypass (RYGBP). Weight loss prediction is helpful to define realistic expectations and maintain motivation during follow-up, but also to select good candidates...
journal_title：Obesity surgery
pub_type： 杂志文章
doi：10.1007/s11695-018-3355-0
更新日期：2018-11-01 00:00:00
abstract：BACKGROUND:YouTube™ is a platform that many people, including patients, use to access health information. Recent studies have revealed that videos on YouTube™ are misleading or that medical videos may not contain appropriate information. This study aimed to assess the quality and reliability of videos on nutrition afte...
journal_title：Obesity surgery
pub_type： 杂志文章
doi：10.1007/s11695-020-05015-z
更新日期：2020-12-01 00:00:00
abstract：:We aimed to systematically review the literature comparing the safety of one-step versus two-step revisional bariatric surgery from laparoscopic adjustable gastric banding (LAGB) to Roux-en-Y gastric bypass (RYGB) or sleeve gastrectomy (SG). There is debate on the safety of removing the gastric band and performing rev...
journal_title：Obesity surgery
pub_type： 杂志文章,meta分析,评审
doi：10.1007/s11695-016-2082-7
更新日期：2016-04-01 00:00:00
abstract：BACKGROUND:Anastomotic ulcers (AUs) after Roux-en-Y gastric bypass (RYGB) occur in up to 16% of patients. In an international survey among members of the International Federation for the Surgery of Obesity and Metabolic Disorders (IFSO), current preventative and therapeutic strategies in AU were analyzed. METHODS:An I...
journal_title：Obesity surgery
pub_type： 杂志文章
doi：10.1007/s11695-013-1152-3
更新日期：2014-05-01 00:00:00
abstract：BACKGROUND:The effect of bariatric surgery on thyroid hormone changes yielded inconsistent results. The aim of the present study was to assess the change of thyroid hormone levels following laparoscopic sleeve gastrectomy (LSG), with or without antral preservation (AP). METHODS:Thyroid hormones (TSH, FT3, FT4) were ex...
journal_title：Obesity surgery
pub_type： 杂志文章
doi：10.1007/s11695-020-04896-4
更新日期：2021-01-01 00:00:00
abstract：:We reviewed the evidence for bariatric surgery reducing the risk of breast cancer. Data was extracted from multiple libraries, including PubMed, EMBASE, and Medline, to perform a systematic review. Abstracts were reviewed by two independent reviewers. Thirty-eight full-text articles were identified from 1171 abstracts...
journal_title：Obesity surgery
pub_type： 杂志文章,meta分析,评审
doi：10.1007/s11695-017-2901-5
更新日期：2017-11-01 00:00:00
abstract：BACKGROUND:Current recommendations suggest postponing pregnancy by at least 1 year after gastric bypass. During the first postoperative year, women are in a catabolic phase with a rapid weight loss which may increase the risk of adverse pregnancy and neonatal outcomes. This study tested the hypothesis that the risk of ...
journal_title：Obesity surgery
pub_type： 杂志文章
doi：10.1007/s11695-013-0903-5
更新日期：2013-08-01 00:00:00
abstract：BACKGROUND:Patients suffering from morbid obesity (MO) have an increased cardiovascular morbidity and mortality. This increased cardiovascular burden is believed to be caused by a sub-inflammatory state through an increased secretion of monocyte chemoattractant protein-1 (MCP-1) by the adipose tissue, resulting in insu...
journal_title：Obesity surgery
pub_type： 杂志文章
doi：10.1007/s11695-009-9917-4
更新日期：2009-11-01 00:00:00
abstract：BACKGROUND:Obese patients with gastroesophageal reflux disease (GERD) refractory to medical therapy are a challenging patient population as obesity is a preoperative predictor of failure after antireflux surgery. We therefore sought to evaluate outcomes using one of two commercially available endoluminal therapies in t...
journal_title：Obesity surgery
pub_type： 杂志文章
doi：10.1007/s11695-008-9715-4
更新日期：2009-06-01 00:00:00
abstract：BACKGROUND AND AIMS:The mechanism of weight loss with the intra-gastric balloon (IGB) is thought to be a decrease in gastric emptying (GE); however the evidence is conflicting. Nausea, abdominal pain, and gastroesophageal reflux disease (GERD) can cause intolerance resulting in early removal. This is demoralizing for t...
journal_title：Obesity surgery
pub_type： 杂志文章
doi：10.1007/s11695-019-04039-4
更新日期：2020-01-01 00:00:00
abstract：BACKGROUND:Biliopancreatic diversion with duodenal switch (BPD-DS) is one of the most effective surgical approaches for the treatment of severe obesity. OBJECTIVE:The objective of this study is to compare perioperative complications and long-term results of open BPD-DS in elderly versus younger patients. METHODS:All ...
journal_title：Obesity surgery
pub_type： 杂志文章
doi：10.1007/s11695-015-1772-x
更新日期：2016-02-01 00:00:00
abstract：:Bariatric surgery is widely accepted as first-choice treatment of morbid obesity and has also shown promising results in the treatment of diabetes and the metabolic syndrome. The number of operations each year is increasing, as well as, consequently, the urgent need for a coordinated nutritional approach, as micronutr...
journal_title：Obesity surgery
pub_type： 杂志文章,评审
doi：10.1007/s11695-008-9489-8
更新日期：2008-11-01 00:00:00
abstract：PURPOSE:In the multidisciplinary therapeutic approach to obesity, bariatric surgery is considered the most effective treatment in weight reduction and the decrease in associated comorbidities. The objective of this work is to describe the long-term clinical and metabolic results in obese patients undergoing biliopancre...
journal_title：Obesity surgery
pub_type： 杂志文章
doi：10.1007/s11695-020-04777-w
更新日期：2020-11-01 00:00:00
abstract：:Obesity is an enduring chronic disease, with multifactorial etiology. Many procedures and solutions have been proposed in the last 25 years. If patients do not meet the criteria for bariatric surgery, intragastric balloons may be used to achieve weight reduction. Contraindications to balloon therapy are a large hiatal...
journal_title：Obesity surgery
pub_type： 杂志文章
doi：10.1381/096089206776944887
更新日期：2006-05-01 00:00:00
abstract：PURPOSE:The number of laparoscopic adjustable gastric banding (LAGB) removal has increased throughout the years. The aim of the study was to evaluate the outcomes in patients undergoing LAGB removal with or without further bariatric surgery. MATERIALS AND METHODS:Data prospectively collected from consecutive patients ...
journal_title：Obesity surgery
pub_type： 杂志文章
doi：10.1007/s11695-018-3373-y
更新日期：2018-11-01 00:00:00
abstract：PURPOSE:Given that smoking is known to contribute to gastrojejunal anastomotic (GJA) ulcers, cessation is recommended prior to laparoscopic Roux-en-Y gastric bypass (LRYGB). However, smoking relapse rates and the exact ulcer risk remain unknown. This study aimed to define smoking relapse, risk of GJA ulceration, and co...
journal_title：Obesity surgery
pub_type： 杂志文章
doi：10.1007/s11695-020-04978-3
更新日期：2020-09-22 00:00:00
abstract：BACKGROUND:Recent studies suggest that weight loss operations may actually increase the costs to society due to increased hospital readmission rates. The purpose of this study was to determine the 30-day readmission rates following bariatric operations at a high volume bariatric surgery program. METHODS:Records for al...
journal_title：Obesity surgery
pub_type： 杂志文章
doi：10.1007/s11695-007-9210-3
更新日期：2007-09-01 00:00:00
abstract：BACKGROUND:The authors evaluated the impact of laparoscopic adjustable gastric banding (LAGB) on obesity-associated diseases in a series at 3 to 8 years postoperatively, namely diabetes, pulmonary disease, hypertension and knee joint pain. METHODS:145 morbidly obese patients underwent LAGB with mean age 38 years and p...
journal_title：Obesity surgery
pub_type： 杂志文章
doi：10.1007/s11695-007-9118-y
更新日期：2007-05-01 00:00:00
