Does Bariatric Surgery Affect the Incidence of Breast Cancer Development? A Systematic Review.

Abstract:

:We reviewed the evidence for bariatric surgery reducing the risk of breast cancer. Data was extracted from multiple libraries, including PubMed, EMBASE, and Medline, to perform a systematic review. Abstracts were reviewed by two independent reviewers. Thirty-eight full-text articles were identified from 1171 abstracts. Four studies were included for meta-analysis; 114 of 10,533 (1.1%) patients receiving bariatric surgery versus 516 of 20,130 (2.6%) controls developed breast cancer, odds ratio 0.564 (95% CI 0.453 to 0.702) using a fixed effects model (P < 0.001) and odds ratio 0.585 (95% CI 0.247 to 1.386) using a random effects model (P 0.223). Bariatric surgery may reduce the risk of breast cancer. More research is required due to heterogeneity of studies, difficulty in identifying accurate controls, and limited follow-up.

journal_name

Obes Surg

journal_title

Obesity surgery

authors

Winder AA,Kularatna M,MacCormick AD

doi

10.1007/s11695-017-2901-5

subject

Has Abstract

pub_date

2017-11-01 00:00:00

pages

3014-3020

issue

11

eissn

0960-8923

issn

1708-0428

pii

10.1007/s11695-017-2901-5

journal_volume

27

pub_type

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