Metabolic Effects of Endoscopic Duodenal Mucosal Resurfacing: a Systematic Review and Meta-analysis.

Abstract:

:Duodenal mucosal resurfacing (DMR) is an innovative endoscopic bariatric and metabolic therapy (EBMT) emerging in recent years. It uses the duodenum to achieve better glycemic and weight control. This study aimed to evaluate in a critical and systematic way the metabolic effects of this procedure. Electronic searches were performed evaluating the DMR procedure based on predefined inclusion and exclusion criteria. Changes in measured outcomes were evaluated using random-effects models by computing weighted mean differences (MD) and corresponding 95% CIs between pre-and post-procedure metabolic characteristics. Four studies were selected for qualitative and quantitative analysis. DMR demonstrated beneficial glycemic and hepatic metabolic effects among patients with non-insulin dependent type 2 diabetes (T2D) at 3 and 6 months post-procedure.

journal_name

Obes Surg

journal_title

Obesity surgery

authors

de Oliveira GHP,de Moura DTH,Funari MP,McCarty TR,Ribeiro IB,Bernardo WM,Sagae VMT,Freitas JR Jr,Souza GMV,de Moura EGH

doi

10.1007/s11695-020-05170-3

subject

Has Abstract

pub_date

2021-01-08 00:00:00

eissn

0960-8923

issn

1708-0428

pii

10.1007/s11695-020-05170-3

pub_type

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