Differential Changes in Gut Microbiota After Gastric Bypass and Sleeve Gastrectomy Bariatric Surgery Vary According to Diabetes Remission.

Abstract:

BACKGROUND:It is unclear whether specific gut microbiota is associated with remission of type 2 diabetes (T2D) after distinct types of bariatric surgery. AIMS:The aim of this study is to examine gut microbiota changes after laparoscopic Roux-en-Y gastric bypass (RYGB) or sleeve gastrectomy (SG) surgery in obese patients with T2D. METHODS:Whole-metagenome shotgun sequencing of DNA fragments using Illumina HiSeq2000 was obtained from stool samples collected from 14 obese T2D patients pre-operatively (while on very low calorie diet) and 1 year after randomisation to laparoscopic SG (n = 7) or RYGB (n = 7). Resulting shotgun reads were annotated with Kyoto Encyclopedia of Genes and Genomes (KEGG). RESULTS:Body weight reduction and dietary change was similar 1 year after both surgery types. Identical proportions (n = 5/7) achieved diabetes remission (HbA1c < 48 mmol/mol without medications) 1 year after RYGB and SG. RYGB resulted in increased Firmicutes and Actinobacteria phyla but decreased Bacteroidetes phyla. SG resulted in increased Bacteroidetes phyla. Only an increase in Roseburia species was observed among those achieving diabetes remission, common to both surgery types. KEGG Orthology and pathway analysis predicted contrasting and greater gut microbiota metabolism changes after diabetes remission following RYGB than after SG. Those with persistent diabetes post-operatively had higher Desulfovibrio species pre-operatively. CONCLUSIONS:Overall, RYGB produces greater and more predicted favourable changes in gut microbiota functional capacity than SG. An increase in Roseburia species was the only compositional change common to both types of surgery among those achieving diabetes remission.

journal_name

Obes Surg

journal_title

Obesity surgery

authors

Murphy R,Tsai P,Jüllig M,Liu A,Plank L,Booth M

doi

10.1007/s11695-016-2399-2

subject

Has Abstract

pub_date

2017-04-01 00:00:00

pages

917-925

issue

4

eissn

0960-8923

issn

1708-0428

pii

10.1007/s11695-016-2399-2

journal_volume

27

pub_type

杂志文章,随机对照试验
  • Bioabsorbable glycolide copolymer staple-line reinforcement decreases internal hernia rate after laparoscopic Roux-en-Y gastric bypass.

    abstract:BACKGROUND:Internal hernias (IHs) can occur after laparoscopic Roux-en-Y gastric bypass (LRYGBP), perhaps because of a lack of adhesion formation at the cut edges of the mesentery and a cutting through of sutures with a decrease in fat from weight loss. In patients undergoing reoperation after LRYGBP, we observed that ...

    journal_title:Obesity surgery

    pub_type: 杂志文章

    doi:10.1007/s11695-007-9404-8

    authors: Ahmed AR,Rickards G,Husain S,Johnson J,O'Malley W,Boss T

    更新日期:2008-07-01 00:00:00

  • Inversion Technique for the Removal of Partially Covered Self-Expandable Metallic Stents.

    abstract:BACKGROUND AND AIMS:Partially covered self-expandable metallic stents (PCSEMS), although an effective treatment for anastomotic/staple line leaks and strictures, can be difficult to remove. This study examines the effectiveness of the inversion technique for the removal of PCSEMS in the treatment of leaks and stricture...

    journal_title:Obesity surgery

    pub_type: 杂志文章

    doi:10.1007/s11695-017-2811-6

    authors: Hill C,Khalil BK,Barola S,Agnihotri A,Moran RA,Chen YI,Ngamruengphong S,Singh VK,Frame LA,Schweitzer MA,Magnuson TH,Khashab MA,Okolo PI 3rd,Kumbhari V

    更新日期:2018-01-01 00:00:00

  • Prediction of whole-body and segmental body composition by bioelectrical impedance in morbidly obese subjects.

    abstract:BACKGROUND:Validated equations for body composition analysis using bioelectrical impedance (BIA) in morbidly obese (MO) subjects are scarce. Thus, our aim was todevelop new equations from physical and BIA parameters to estimate whole-body and segmental body composition inMO subjects, with dual-energy X-ray absorptiomet...

    journal_title:Obesity surgery

    pub_type: 杂志文章

    doi:10.1007/s11695-011-0570-3

    authors: Jiménez A,Omaña W,Flores L,Coves MJ,Bellido D,Perea V,Vidal J

    更新日期:2012-04-01 00:00:00

  • Improving Nausea and Vomiting Post-Elipse Balloon: a Novel Single-Dose Regimen of 300 mg Netupitant/0.5 mg Palonosetron Hydrochloride.

    abstract:BACKGROUND:Post intragastric balloon placement symptoms like nausea and vomiting have been the major cause of a high rate of early removal. Common therapy with ondansetron alone, or in combination, with prokinetic agents have been shown to have very little or no effect. Recently, an improved therapy based on aprepitant...

    journal_title:Obesity surgery

    pub_type: 杂志文章,多中心研究

    doi:10.1007/s11695-019-03937-x

    authors: Ienca R,Giardiello C,Scozzarro A,di Cola RS,Di Lorenzo N,Juneja G,Lopez G,Badiuddin F

    更新日期:2019-09-01 00:00:00

  • Surgical Management of a Chronic Sleeve Gastrocolic Fistula with Near Total Gastrectomy and Roux-en-Y Reconstruction.

    abstract:BACKGROUND:Management of the leak is determined by the duration of the leak from the initial surgery. Acute leaks occurring less than 72 hours after surgery are best managed with reoperation and primary repair. Intermediate leaks, greater than 72 hours but less than 12 weeks, can be managed with non-operative managemen...

    journal_title:Obesity surgery

    pub_type: 杂志文章

    doi:10.1007/s11695-020-04689-9

    authors: Dugan N,Nimeri A

    更新日期:2020-09-01 00:00:00

  • Vertical Banded Gastroplasty-Gastric Bypass: preliminary report.

    abstract::Vertical banded gastroplasty-gastric bypass is a surgical technique combining the advantages of the vertical banded gastroplasty with those of gastric bypass. The procedure was performed on 148 morbidly obese individuals: 83% were female, and 17% were male. Ages ranged from 15 to 64 years, with a mean age of 35. Mean ...

    journal_title:Obesity surgery

    pub_type: 杂志文章

    doi:10.1381/096089291765560782

    authors: Capella RF,Capella JF,Mandec H,Nath P

    更新日期:1991-12-01 00:00:00

  • Correction to: Clinical Practice Guidelines for Childbearing Female Candidates for Bariatric Surgery, Pregnancy, and Post-Partum Management after Bariatric Surgery.

    abstract::In the original article, due to an XML tagging error the name of Véronique Taillard was omitted from the list of members of the French Study Group for Bariatric Surgery and Maternity (the BARIA-MAT Group). The correct list is as follows. ...

    journal_title:Obesity surgery

    pub_type: 已发布勘误

    doi:10.1007/s11695-020-04479-3

    authors: Ciangura C,Coupaye M,Deruelle P,Gascoin G,Calabrese D,Cosson E,Ducarme G,Gaborit B,Lelièvre B,Mandelbrot L,Petrucciani N,Quilliot D,Ritz P,Robin G,Sallé A,Gugenheim J,Nizard J,BARIA-MAT Group.

    更新日期:2020-09-01 00:00:00

  • Short- and long-term outcomes of vertical banded gastroplasty converted to Roux-en-Y gastric bypass.

    abstract:BACKGROUND:Vertical banded gastroplasty (VBG) often necessitates revisional surgery for weight regain or symptoms related to gastric outlet obstruction. Roux-en-Y gastric bypass (RYGB) is considered as the revisional procedure of choice. However, revisional bariatric surgery is associated with relatively higher rates o...

    journal_title:Obesity surgery

    pub_type: 杂志文章

    doi:10.1007/s11695-012-0796-8

    authors: Vasas P,Dillemans B,Van Cauwenberge S,De Visschere M,Vercauteren C

    更新日期:2013-02-01 00:00:00

  • An Investigation of the Eating Concerns Scale of the Minnesota Multiphasic Personality Inventory-3 (MMPI-3) in a Postoperative Bariatric Surgery Sample.

    abstract::Eating pathology is common pre-operatively and continues to be prevalent following bariatric surgery. A new version of the Minnesota Multiphasic Personality Inventory (MMPI), the MMPI-3, contains a new scale called Eating Concerns (EAT) that aims to assess problematic eating behaviors. The current investigation seeks ...

    journal_title:Obesity surgery

    pub_type: 杂志文章

    doi:10.1007/s11695-020-05113-y

    authors: Marek RJ,Martin-Fernandez K,Heinberg LJ,Ben-Porath YS

    更新日期:2020-11-16 00:00:00

  • Achalasia-like disorder after laparoscopic adjustable gastric banding: a reversible side effect?

    abstract::Literature data concerning the effect of laparoscopic adjustable gastric banding (LAGB) on esophageal motility are conflicting. Achalasia-like disorder involving the absence of esophageal peristalsis and impaired esophago-gastric junction (EGJ) is probably under-estimated and can result in failure and band removal. Th...

    journal_title:Obesity surgery

    pub_type: 杂志文章

    doi:10.1007/s11695-012-0627-y

    authors: Robert M,Golse N,Espalieu P,Poncet G,Mion F,Roman S,Boulez J,Gouillat C

    更新日期:2012-05-01 00:00:00

  • Use of an Endoscopic Suturing Platform for the Management of Staple Line Dehiscence After Laparoscopic Sleeve Gastrectomy.

    abstract:BACKGROUND:Management of staple line dehiscence following laparoscopic sleeve gastrectomy (LSG) varies based on local expertise and timing of presentation. We present our experience with an endoscopic suturing platform to treat patients with staple line dehiscence following LSG. METHODS:We included all patients who pr...

    journal_title:Obesity surgery

    pub_type: 杂志文章

    doi:10.1007/s11695-019-04344-y

    authors: Lamb LC,Lawlor MK,Tishler DS,Seip RL,Karasik M,McLaughlin T,Papasavas PK

    更新日期:2020-03-01 00:00:00

  • Medial thigh lift free flap for autologous breast augmentation after bariatric surgery.

    abstract:BACKGROUND:Massive weight loss following bariatric surgery frequently results in body contour deformities like ptotic and hypoplastic breasts, redundant abdominal tissue and loose skin especially in the medial thigh area. This redundant tissue can be used for breast augmentation in the case of hypertrophic ptotic breas...

    journal_title:Obesity surgery

    pub_type: 杂志文章

    doi:10.1381/096089202320995655

    authors: Schoeller T,Meirer R,Otto-Schoeller A,Wechselberger G,Piza-Katzer H

    更新日期:2002-12-01 00:00:00

  • Routine abdominal drains after laparoscopic sleeve gastrectomy: a retrospective review of 353 patients.

    abstract::Complications after laparoscopic sleeve gastrectomy (LSG) are usually silent and difficult to interpret. Our purpose was to evaluate the utility of routine placement of intraperitoneal drains at the end of LSG in detection and management of postoperative complications. This is a retrospective study of all patients tha...

    journal_title:Obesity surgery

    pub_type: 杂志文章

    doi:10.1007/s11695-010-0343-4

    authors: Albanopoulos K,Alevizos L,Linardoutsos D,Menenakos E,Stamou K,Vlachos K,Zografos G,Leandros E

    更新日期:2011-06-01 00:00:00

  • Laparoscopic Sleeve Gastrectomy With or Without Staple Line Inversion and Distal Fixation to the Transverse Mesocolon: Impact on Early Postoperative Outcomes.

    abstract:BACKGROUND AND AIM:Staple line complications and axial rotation of the gastric tube after sleeve gastrectomy are well-recognized complications of the procedure. The present study aims to investigate the role of staple line inversion and distal fixation to the transverse mesocolon in reducing these complications. PATIE...

    journal_title:Obesity surgery

    pub_type: 杂志文章

    doi:10.1007/s11695-016-2277-y

    authors: Abdallah E,Emile SH,Elfeki H

    更新日期:2017-02-01 00:00:00

  • The impact of socioeconomic factors on patient preparation for bariatric surgery.

    abstract:BACKGROUND:Socioeconomic factors (SEF) influence bariatric surgery access and outcomes perhaps because of variations in patient knowledge and behaviors. This study examines the associations between income, formal education, race, health insurance, employment status, and patient self-educational and behavioral activitie...

    journal_title:Obesity surgery

    pub_type: 杂志文章

    doi:10.1007/s11695-009-9889-4

    authors: Balduf LM,Kohn GP,Galanko JA,Farrell TM

    更新日期:2009-08-01 00:00:00

  • One Anastomosis Gastric Bypass/Minigastric Bypass in Patients with BMI 

    abstract:INTRODUCTION:Obesity in the world has been increasing, and the number of diabetic patients will increase by 114%, and the best treatment results are achieved through surgery. Several techniques have been described; the gastric bypass of an anastomosis (MGB/OAGB) has been gaining popularity for its simplicity and good r...

    journal_title:Obesity surgery

    pub_type: 临床试验,杂志文章

    doi:10.1007/s11695-019-04071-4

    authors: Navarrete Aulestia S,Leyba JL,Navarrete Llopis S,Pulgar V

    更新日期:2019-12-01 00:00:00

  • Management of Type 2 Late Sleeve Leak by Laparoscopic Suturing and Conversion to Roux-en-Y Gastric Bypass: Video Report.

    abstract:BACKGROUND:Laparoscopic sleeve forming gastrectomy (SFG) is a commonly performed bariatric procedure for the surgical management of morbid obesity. Staple line gastric leaks occur infrequently but are the most feared complication causing prolonged morbidity (Burgos et al., Obes Surg 19(12):1672-7, 2009; Márquez et al.,...

    journal_title:Obesity surgery

    pub_type: 杂志文章

    doi:10.1007/s11695-015-1813-5

    authors: Praveenraj P,Gomes RM,Kumar S,Senthilnathan P,Parthasarathi R,Rajapandian S,Palanivelu C

    更新日期:2015-10-01 00:00:00

  • Laparotomic vs laparoscopic lap-band: 4-year results with early and intermediate complications.

    abstract:BACKGROUND:Adjustable banding is safe, low invasive, and effective for losing weight. METHODS:69 patients underwent this procedure by laparotomy or laparoscopy. RESULTS:Patients operated by laparotomy lost more weight than those operated by laparoscopy, but in 4 patients we were forced to re-operate in order to remov...

    journal_title:Obesity surgery

    pub_type: 杂志文章

    doi:10.1381/096089200321643584

    authors: De Luca M,de Werra C,Formato A,Formisano C,Loffredo A,Naddeo M,Forestieri P

    更新日期:2000-06-01 00:00:00

  • Surgical treatment of morbid obesity by adjustable gastric band: the case for a conservative strategy in the case of failure - a 9-year series.

    abstract:BACKGROUND:Lapaparoscopic adjustable gastric banding (LAGB) has become a widespread method to treat morbid obesity. Long-term complications and failures require a strategy for reoperation. METHODS:1,180 patients have been operated on from April 1995 to December 2003. 151 had reoperation for complications (12.7%) exclu...

    journal_title:Obesity surgery

    pub_type: 杂志文章

    doi:10.1381/0960892041719545

    authors: Dargent J

    更新日期:2004-08-01 00:00:00

  • Gut hormones and leptin: impact on energy control and changes after bariatric surgery--what the future holds.

    abstract::Obesity is now considered the new world epidemic. In an attempt to face this menace to public health, several treatments, apart from the traditional nutritional modification and oral medication, have been introduced, among them bariatric surgery and gut hormone-based treatments. The gastrointestinal (GI) tract is a po...

    journal_title:Obesity surgery

    pub_type: 杂志文章,评审

    doi:10.1007/s11695-012-0698-9

    authors: Michalakis K,le Roux C

    更新日期:2012-10-01 00:00:00

  • Predictors of prolonged hospital stay following open and laparoscopic gastric bypass for morbid obesity: body mass index, length of surgery, sleep apnea, asthma, and the metabolic syndrome.

    abstract:BACKGROUND:The number of weight reduction operations performed for type II and type III obesity is rapidly escalating. Risk of surgery has been infrequently stratified for patient subgroups. The purpose of this study was to identify patient characteristics that increased the odds of a prolonged hospital length of stay ...

    journal_title:Obesity surgery

    pub_type: 杂志文章

    doi:10.1381/0960892041975460

    authors: Ballantyne GH,Svahn J,Capella RF,Capella JF,Schmidt HJ,Wasielewski A,Davies RJ

    更新日期:2004-09-01 00:00:00

  • Knowledge and Attitudes Towards Obesity and Bariatric Surgery in Chinese Nurses.

    abstract:BACKGROUND:Obesity has become a global epidemic. Surgical treatment of obesity and metabolic disorders in China is increasing rapidly, but it is still a new discipline even to health professionals. As an important member of the multidisciplinary team, the knowledge and attitudes of nurses provide crucial health care to...

    journal_title:Obesity surgery

    pub_type: 杂志文章

    doi:10.1007/s11695-019-04173-z

    authors: Fan M,Hong J,Cheung PN,Tang S,Zhang J,Hu S,Jiang S,Chen X,Yu S,Gao L,Wang C,Chen W,Yang W

    更新日期:2020-02-01 00:00:00

  • Laparoscopic Roux-en-Y Gastric Bypass for Failed Gastric Banding: One-Step or Two-Step Revisional Surgery?

    abstract:BACKGROUND:Surgical revision rates are high, reaching 41% at 10 years after Laparoscopic gastric band (LAGB). Surgical revision may include re-banding, laparoscopic sleeve gastrectomy (LSG), duodenal switch (DS), or laparoscopic Roux-en-Y gastric bypass (LRYGB). LRYGBP has been proposed as the procedure of choice after...

    journal_title:Obesity surgery

    pub_type: 杂志文章

    doi:10.1007/s11695-020-05027-9

    authors: Alratrout H,Almuttawa A,Siciliano I,Keller P

    更新日期:2020-10-14 00:00:00

  • Long-Term Quality of Life Outcomes After Laparoscopic Sleeve Gastrectomy and Roux-en-Y Gastric Bypass-a Comparative Study.

    abstract::Roux-en-Y gastric bypass (RYGB) and sleeve gastrectomy (SG) have been shown to improve metabolic comorbidities as well as quality of life (QoL) in the obese population. The vast majority of previous studies have investigated the metabolic effects of bariatric surgery and there is a dearth of studies examining long-ter...

    journal_title:Obesity surgery

    pub_type: 杂志文章

    doi:10.1007/s11695-020-05049-3

    authors: Fiorani C,Coles SR,Kulendran M,McGlone ER,Reddy M,Khan OA

    更新日期:2020-10-16 00:00:00

  • Laparoscopic Roux En Y Esophago-Jejunostomy for Chronic Leak/Fistula After Laparoscopic Sleeve Gastrectomy.

    abstract:BACKGROUND:Leak following laparoscopic sleeve gastrectomy (LSG) is one of the most serious and devastating complications. Endoscopic stents can treat most early LSG leaks, but is not as effective for chronic LSG leaks/fistulae. The surgical options to treat a chronic leak/fistula after LSG are laparoscopic Roux en Y es...

    journal_title:Obesity surgery

    pub_type: 杂志文章

    doi:10.1007/s11695-015-2018-7

    authors: Mahmoud M,Maasher A,Al Hadad M,Salim E,Nimeri AA

    更新日期:2016-03-01 00:00:00

  • Psychological Effects of Vertical Banded Gastroplasty on Pathologically Obese Patients.

    abstract::For a period of 2 years the authors have examined on 16 pathologically obese patients the psychological effects of the weight loss resulting from vertical banded gastroplasty. At the time of surgery the patients' average age was 41 years. The patients' average weight of 125.9 kg (range 110-150 kg) decreased after surg...

    journal_title:Obesity surgery

    pub_type: 杂志文章

    doi:10.1381/096089292765560114

    authors: La Manna A,Ricci GB,Giorgi I I,Gossemburg M,La Manna L,Catona A

    更新日期:1992-08-01 00:00:00

  • Conversion from Duodenal Switch to Single Anastomosis Duodenal Switch to Deal with Postoperative Malnutrition.

    abstract:BACKGROUND:Duodenal switch (DS) is considered one of the most effective bariatric techniques for long-term weight and comorbidity control. After these operations, some patients may get severe complications related to malnutrition and a few of them may need surgical revision. Lengthening the common channel (CC) is usual...

    journal_title:Obesity surgery

    pub_type: 杂志文章

    doi:10.1007/s11695-020-05047-5

    authors: Baltar J,Martis-Sueiro A,Pardo M,Santos F,Sartal MI,Crujeiras AB,Peinó R,Seoane LM,Bárcena M,Bustamante M

    更新日期:2021-01-01 00:00:00

  • Stomach Volume Assessment Using Three-dimensional Computed Tomography Gastrography for Bariatric Treatment.

    abstract:BACKGROUND:Most bariatric treatments employ gastric volume reduction. However, there has been no appropriate tool that could assess the anatomical factors of the stomach, and few studies have investigated proper stomach measurement for bariatric treatment. Thus, this study aimed to objectively estimate the individual s...

    journal_title:Obesity surgery

    pub_type: 杂志文章

    doi:10.1007/s11695-019-04189-5

    authors: Kim SH,Keum B,Choi HS,Kim ES,Seo YS,Jeen YT,Lee HS,Chun HJ,Um SH,Kim CD

    更新日期:2020-02-01 00:00:00

  • Effects and Mechanisms of Vagal Nerve Stimulation on Body Weight in Diet-Induced Obese Rats.

    abstract:BACKGROUND:Vagal nerve stimulation (VNS) has recently been indicated as a novel method for treating obesity. However, the optimal stimulation parameters were unknown and mechanisms were poorly understood. The aim of this study was to investigate the effects of VNS on food intake and body weight in diet-induced obesity ...

    journal_title:Obesity surgery

    pub_type: 杂志文章

    doi:10.1007/s11695-019-04365-7

    authors: Dai F,Yin J,Chen JDZ

    更新日期:2020-03-01 00:00:00

  • Endoscopic findings of asymptomatic patients one year after Roux-en-Y gastric bypass for treatment of obesity.

    abstract:BACKGROUND:In the late post-operative period, the necessity of performing an upper gastrointestinal endoscopy (GIE) to check for complications is controversial. Some authors suggest it should be routine for all patients, others selectively, but not all patients with endoscopic abnormalities are symptomatic and some abn...

    journal_title:Obesity surgery

    pub_type: 杂志文章

    doi:10.1007/s11695-013-0936-9

    authors: Spinosa SR,Valezi AC

    更新日期:2013-09-01 00:00:00