Abstract:
OBJECTIVE:To determine possible preoperative predictors for obtaining clinically meaningful weight loss with gastric electrical stimulation (GES) using the "Three-Factor Eating Questionnaire" (TFEQ) as well as epidemiological data. METHODS:Ninety-seven obese participants in a prospective multicenter randomized study conducted in nine European centers were implanted laparoscopically with the abiliti® closed-loop GES system (CLGES). Five clinical variables and three preoperative TFEQ factor scores (F1-cognitive-restraint, F2-disinhibition, and F3-hunger) were analyzed in order to determine predictors of weight loss success defined as excess weight loss (EWL) > 30% and failure defined as EWL < 20% at 12 months post-surgery. RESULTS:The mean 12-month %EWL with CLGES was 35.1 ± 19.7%, with a success rate of 52% and a failure rate of 19%. Significant predictors of success were body mass index (BMI) < 40 kg/m2 and age ≥ 50 years, increasing probability of success by 22 and 29%, respectively. A low F1-cognitive-restraint score was a significant predictor of failure (p = 0.004). The best predictive model for success included F1-cognitive-restraint, F2-disinhibition, BMI < 40, and age ≥ 50 (p = 0.002). CONCLUSION:This retrospective analysis has shown that age, preoperative BMI, and F1-cognitive-restraint and F2-disinhibition scores from a preoperatively administered TFEQ are predictive of weight loss outcomes with CLGES and may be used for patient selection. TRIAL REGISTRATION:ClinicalTrials.gov Identifier: NCT01448785.
journal_name
Obes Surgjournal_title
Obesity surgeryauthors
Alarcón Del Agua I,Socas-Macias M,Busetto L,Torres-Garcia A,Barranco-Moreno A,Garcia de Luna PP,Morales-Conde Sdoi
10.1007/s11695-016-2495-3subject
Has Abstractpub_date
2017-06-01 00:00:00pages
1573-1580issue
6eissn
0960-8923issn
1708-0428pii
10.1007/s11695-016-2495-3journal_volume
27pub_type
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