Abstract：
BACKGROUND:Hepatitis C virus (HCV) is an important cause of liver cirrhosis and its complications. The safety and efficacy of bariatric surgery in patients with HCV infection is not clear. METHODS:Charts were reviewed to identify patients with HCV infection before bariatric surgery. Bariatric surgical patients with non-alcoholic steatohepatitis (NASH) and without NASH (non-NASH) were recruited as comparative groups. Demographic variables, perioperative data, follow-up, and HCV-related parameters were extracted and compared. RESULTS:Forty-seven bariatric patients between 2000 and 2016 that suffered from HCV infection were identified. The mean age and body mass index (BMI) at baseline were 34.5 ± 9.9 years and 40.4 ± 7.7 kg/m2, respectively. The HCV(+) group was associated with female sex, older age, lower BMI, and waist circumference than both NASH and non-NASH groups. Both HCV(+) and NASH groups had higher liver function tests and incidence of metabolic syndrome than non-NASH group. The HCV(+) group had lower uric acid and albumin level than the NASH group. Early major postoperative complication occurred in 1 (2.1%) patient of the HCV(+) group. At follow-up, the mean BMI decreased to 29.1 ± 7.1 kg/m2 and total weight loss was 25% for the HCV(+) group at 5 years after surgery. The weight loss curves were similar between the HCV(+) group and NASH group. During follow-up, no patients died but one patient with HCV(+) developed flare up of hepatitis after gastric bypass. The mean liver transaminase level remained in normal range for the HCV(+) group. CONCLUSION:Co-existence of HCV infection does not influence the outcome of bariatric surgery but continued monitoring of the liver function is indicated.
journal_name
Obes Surgjournal_title
Obesity surgeryauthors
Han ML,Lee WJ,Chen JC,Ser KH,Chen SC,Lee YCdoi
10.1007/s11695-018-3615-zsubject
Has Abstractpub_date
2019-03-01 00:00:00pages
828-834issue
3eissn
0960-8923issn
1708-0428pii
10.1007/s11695-018-3615-zjournal_volume
29pub_type
杂志文章相关文献
OBESITY SURGERY文献大全abstract：BACKGROUND:Obesity and type 2 diabetes mellitus (T2DM) represent significant healthcare burdens. Surgical management is superior to traditional medical therapy. Laparoscopic sleeve gastrectomy (LSG) and gastric bypass (both Roux-en-Y (RYGB) and one anastomosis gastric bypass (OAGB) are the most commonly performed metab...
journal_title：Obesity surgery
pub_type： 杂志文章
doi：10.1007/s11695-020-04921-6
更新日期：2020-12-01 00:00:00
abstract：INTRODUCTION:Laparoscopic sleeve gastrectomy (LSG) has rapidly become popular with excellent results. However, LSG may exacerbate or increase the risk of "de novo" gastroesophageal reflux disease (GERD). Adding a fundoplication has been proposed to increase the lower esophageal sphincter competency. The aim of this stu...
journal_title：Obesity surgery
pub_type： 杂志文章
doi：10.1007/s11695-020-05189-6
更新日期：2021-01-03 00:00:00
abstract：BACKGROUND:Despite the established efficacy and safety of laparoscopic sleeve gastrectomy (LSG), controversy still exists on optimal operative technique, the resection distance from pylorus (DP) being among the most controversial issues. This study aimed to examine the effect of resection distance from pylorus on % exc...
journal_title：Obesity surgery
pub_type： 杂志文章
doi：10.1007/s11695-019-03923-3
更新日期：2019-09-01 00:00:00
abstract：BACKGROUND:The association of obesity with atrial fibrillation (AF) and with ventricular arrhythmias is well documented. OBJECTIVE:The aim of this study was to investigate whether weight reduction by a laparoscopic sleeve gastrectomy has any effect on P wave dispersion (PWD), a predictor of AF, and corrected QT interv...
journal_title：Obesity surgery
pub_type： 临床试验,杂志文章
doi：10.1007/s11695-017-2923-z
更新日期：2018-04-01 00:00:00
abstract：INTRODUCTION:miRNAs are small non-coding RNAs, some of which are expressed in adipose tissues, are present in the circulation, and are regulated in obesity. Bariatric surgery (BS) has been proposed to lead to activation of brown adipose tissue, an effect that may be related to beneficial effects of BS on systemic metab...
journal_title：Obesity surgery
pub_type： 杂志文章
doi：10.1007/s11695-019-04104-y
更新日期：2020-01-01 00:00:00
abstract：BACKGROUND:Revisional surgery has become a widely accepted alternative for weight loss failure/regain after bariatric surgery. However, it is associated to higher morbi-mortality and lesser weight loss than primary bariatric procedure. Our aims are to present a novel technique for weight loss treatment after failed lap...
journal_title：Obesity surgery
pub_type： 杂志文章
doi：10.1007/s11695-014-1463-z
更新日期：2015-04-01 00:00:00
abstract：BACKGROUND:Our aim was to assess, in obese patients undergoing Roux-en Y gastric bypass surgery, the cumulative Helicobacter pylori (HP) eradication rates in two consecutive time spans (2006-2008 and 2009-2010). METHODS:The study adopted a 14-day clarithromycin-based triple therapy in first-line treatment as proposed ...
journal_title：Obesity surgery
pub_type： 杂志文章
doi：10.1007/s11695-012-0747-4
更新日期：2013-02-01 00:00:00
abstract：:There is more to losing weight, maintaining weight and choosing a healthy diet after gastric bypass than simply limiting food intake and avoiding sugars. Patients must learn to make food selections that have a high nutrient:energy ratio. Considerable research indicates that the dietary fat level, independent of total ...
journal_title：Obesity surgery
pub_type： 杂志文章
doi：10.1381/096089292765559990
更新日期：1992-11-01 00:00:00
abstract：:A 32-year-old female patient with morbid obesity (body mass index 44.4) was submitted to upper digestive endoscopy performed routinely as a preoperative procedure in bariatric surgery. The examination identified multiple small polypoid lesions in the upper portion of the gastric body, some with small ulcerations. Anat...
journal_title：Obesity surgery
pub_type： 杂志文章
doi：10.1007/s11695-007-9342-5
更新日期：2008-06-01 00:00:00
abstract：BACKGROUND:The authors evaluated the impact of laparoscopic adjustable gastric banding (LAGB) on obesity-associated diseases in a series at 3 to 8 years postoperatively, namely diabetes, pulmonary disease, hypertension and knee joint pain. METHODS:145 morbidly obese patients underwent LAGB with mean age 38 years and p...
journal_title：Obesity surgery
pub_type： 杂志文章
doi：10.1007/s11695-007-9118-y
更新日期：2007-05-01 00:00:00
abstract：BACKGROUND:Roux-en-Y gastric bypass (LRYGB) has weight-independent effects on glycemia in obese type 2 diabetic patients, whereas sleeve gastrectomy (LSG) is less well characterized. This study aims to compare early weight-independent and later weight-dependent glycemic effects of LRYGB and LSG. METHODS:Eighteen LRYGB...
journal_title：Obesity surgery
pub_type： 杂志文章,多中心研究,随机对照试验
doi：10.1007/s11695-017-3061-3
更新日期：2018-06-01 00:00:00
abstract：:A 33-year-old, morbidity obese woman underwent a laparoscopic Roux-en-Y gastric bypass in November 2004. She presented 18 months later with a history of recurrent pain in the upper region of the abdomen and severe vomiting. Radiologic and endoscopic evaluations revealed wall thickening in the transverse colon and a so...
journal_title：Obesity surgery
pub_type： 杂志文章
doi：10.1007/s11695-007-9189-9
更新日期：2007-08-01 00:00:00
abstract：BACKGROUND:As our bariatric program matured, we noted that length of stay (LOS) steadily decreased. This led us to analyze our experience to identify factors contributing to this abbreviated LOS and to evaluate the safety of discharging patients with only a 2-day LOS. METHODS:All patients undergoing open Roux-en-Y gas...
journal_title：Obesity surgery
pub_type： 杂志文章
doi：10.1381/096089204772787257
更新日期：2004-01-01 00:00:00
abstract：BACKGROUND:There are no agreed definitions as to what constitutes a 'failure' of the primary bariatric procedure in relation to weight loss. METHODS:The MEDLINE database for primary research articles was searched using obesity [title] or bariatric [title] and revision [title] or revisional [title]. RESULTS:The MEDLIN...
journal_title：Obesity surgery
pub_type： 杂志文章,评审
doi：10.1007/s11695-014-1541-2
更新日期：2015-03-01 00:00:00
abstract：BACKGROUND:Previous studies have reported that risk factors for elevated mortality after Roux-en-Y gastric bypass include male gender, as well as a very elevated BMI. The present study was aimed at determining whether these same risk factors applied to patients undergoing the duodenal switch (DS) operation. MATERIALS ...
journal_title：Obesity surgery
pub_type： 杂志文章
doi：10.1381/0960892053923699
更新日期：2005-05-01 00:00:00
abstract：PURPOSE:A subpopulation of weight loss surgery (WLS) patients endorse cannabis and/or opioid use; however, impact on post-WLS anxiety and depression is unclear. This study examined the influence of the independent and combined use of cannabis and opioids on (1) depression and anxiety, (2) duodenum serotonin and cortiso...
journal_title：Obesity surgery
pub_type： 杂志文章
doi：10.1007/s11695-020-04828-2
更新日期：2020-11-01 00:00:00
abstract：BACKGROUND:The effects of surgical weight loss (WL) on inflammatory biomarkers associated with sleep apnea remain unknown. We sought to determine if any biomarkers can predict amelioration of sleep apnea achieved by bariatric surgery. We hypothesized that surgical WL would substantially reduce severity of sleep apnea a...
journal_title：Obesity surgery
pub_type： 临床试验,杂志文章
doi：10.1007/s11695-011-0359-4
更新日期：2011-09-01 00:00:00
abstract：PURPOSE:Obesity is a major risk factor for nonalcoholic fatty liver disease (NAFLD), affecting 25% of the worldwide population. Weight loss through bariatric surgery can improve much of the liver steatosis, inflammation, and fibrosis. However, it is not known whether there is reversal of the elastic fiber deposition pr...
journal_title：Obesity surgery
pub_type： 杂志文章
doi：10.1007/s11695-020-04722-x
更新日期：2020-10-01 00:00:00
abstract：BACKGROUND:Laparoscopic gastric bypass (LGBP) is being performed widely as a treatment of choice for morbid obesity. Advantages over open gastric bypass (OGBP) have not been well documented in controlled studies. The aim of this study is to evaluate the early postoperative outcomes after LGBP and OGBP using a matched p...
journal_title：Obesity surgery
pub_type： 杂志文章
doi：10.1381/096089203765887624
更新日期：2003-06-01 00:00:00
abstract：BACKGROUND:Early or late pouch dilatations account for a moderate complication rate after restrictive bariatric operations. Various strategies were developed to prevent or treat pouch dilatations. METHODS:A case of necrosis of gastric wall in a concentric dilated pouch following laparoscopic adjustable gastric banding...
journal_title：Obesity surgery
pub_type： 杂志文章
doi：10.1381/09608920160558768
更新日期：2001-12-01 00:00:00
abstract：BACKGROUND:Laparoscopic sleeve gastrectomy (LSG) as a single-stage procedure has shown to be effective in achieving significant weight loss and resolving obesity-related co-morbidities. However, its nutrition consequences have not been extensively explored. This study aims to investigate weight loss and evolution of nu...
journal_title：Obesity surgery
pub_type： 杂志文章
doi：10.1007/s11695-016-2211-3
更新日期：2016-12-01 00:00:00
abstract：BACKGROUND:Abnormal glucose profiles have been described after Roux-en-Y gastric bypass (RYGB) with intense postprandial hyperglycemic peaks in some but not all the patients. The underlying mechanisms of these anomalies are not totally understood. OBJECTIVE:The aim of this study is to determine whether or not the comp...
journal_title：Obesity surgery
pub_type： 杂志文章
doi：10.1007/s11695-015-1930-1
更新日期：2016-07-01 00:00:00
abstract：BACKGROUND:Preliminary data suggest that patients with actively treated depression should expect the same outcomes after surgery. The objective of this study was to compare weight loss 12 months after gastric bypass surgery in patients taking antidepressants before surgery (AD) versus those who were not (non-AD). METH...
journal_title：Obesity surgery
pub_type： 杂志文章
doi：10.1007/s11695-010-0351-4
更新日期：2011-11-01 00:00:00
abstract：BACKGROUND:Susceptibility to obesity is associated with a notable inter-individual variation. The aim of the present study was to compare the effectiveness of sleeve gastrectomy (SG) on weight loss and metabolic profile in obesity-prone (OP) rats vs animals that are non-susceptible to obesity (NSO). METHODS:Young male...
journal_title：Obesity surgery
pub_type： 杂志文章
doi：10.1007/s11695-015-1915-0
更新日期：2016-07-01 00:00:00
abstract：BACKGROUND:Previously, we demonstrated the safety and efficacy of laparoscopic gastric bypass surgery in patients over 65 years of age. The aim of this study is to demonstrate the safety and efficacy of this procedure as a final step for treatment of morbid obesity in the same population. METHODS:A retrospective revie...
journal_title：Obesity surgery
pub_type： 杂志文章
doi：10.1007/s11695-013-0992-1
更新日期：2013-09-01 00:00:00
abstract：BACKGROUND:Although laparoscopic adjustable gastric banding (LAGB) has been found to be a generally successful weight loss operation, there are reports of occasional LAGB failure. The results of rescue procedures for these patients are important. The mini-gastric bypass (MGB) is a safe and effective alternative to othe...
journal_title：Obesity surgery
pub_type： 杂志文章
doi：10.1381/096089206776327387
更新日期：2006-04-01 00:00:00
abstract：BACKGROUND:Biliopancreatic diversion (BPD) has been shown to be one of the most effective techniques for losing weight, although the relationship between body composition and diet after the procedure is not well known. Our aim was to assess dietary changes and their effects on body composition. METHODOLOGY:This longit...
journal_title：Obesity surgery
pub_type： 杂志文章
doi：10.1007/s11695-015-1658-y
更新日期：2015-11-01 00:00:00
abstract：BACKGROUND:Breast reduction surgery is common in females; however, in males it is mainly due to gynecomastia. After weight reduction following obesity surgery, it is a problem in women, but also in some men. METHOD:One patient is described in whom the weight reduction declined from BMI 52 to BMI 36 after vertical band...
journal_title：Obesity surgery
pub_type： 杂志文章
doi：10.1381/096089299765552819
更新日期：1999-10-01 00:00:00
abstract：:Considerable controversy exists about the perioperative management of patients at high risk for obstructive sleep apnea (OSA) in free-standing clinics. Eighty-eight percent of an American Society of Anesthesiologists expert panel felt that upper abdominal laparoscopic surgery could not be performed safely on an outpat...
journal_title：Obesity surgery
pub_type： 杂志文章
doi：10.1007/s11695-011-0381-6
更新日期：2011-10-01 00:00:00
abstract：BACKGROUND:The degree to which U.S. bariatric surgeons use multidisciplinary methods to evaluate patients is unknown. METHODS:We conducted a national survey of practising bariatric surgeons, mailed in 3 waves from September-December 2004, to describe and determine predictors of surgeons' approach to the multidisciplin...
journal_title：Obesity surgery
pub_type： 杂志文章
doi：10.1381/096089206775222096
更新日期：2006-01-01 00:00:00
