[Thyroid stimulating hormone reference values derived from the 2009-2010 Chilean National Health Survey].

Abstract:

BACKGROUND:The determination of thyroid stimulating hormone (TSH) reference values is critical for the diagnosis of thyroid diseases. AIM:To explore and discuss different definitions to establish TSH reference values using a Chilean national survey sample. MATERIAL AND METHODS:The 2009-2010 Chilean National Health Survey recruited 5,416 participants between the ages of 15 and 96 years, from all geographic regions of Chile, including urban and rural zones. TSH was measured in a random subsample of 2,785 adults. Median value, 2.5 and 97.5 percentiles were described in three different populations: total survey population, "disease-free population" and the "laboratory kit disease free population". RESULTS:TSH values were higher among women, the elderly and the less educated population. The 97.5 percentile value in the disease-free population was 7.46 uUl/ml. Using this value as a cut-off, hypothyroidism prevalence would be 4.8% in Chile and estimated pharmacological treatment coverage would be 58%. When laboratory kit cut-offs are used, prevalence rises to 22% and treatment coverage drops to 12%. The 2.5 percentile value in the disease-free population was 0.83 uUl/ml, which yields an estimated hyperthyroidism prevalence of 3.89%. CONCLUSIONS:Median TSH concentration values in the Chilean "disease-free population" are higher than those proposed by laboratory kits and those of developed countries. TSH values in the general population of Chile are also higher in women, the elderly and the less educated population.

journal_name

Rev Med Chil

journal_title

Revista medica de Chile

authors

Mosso L,Margozzini P,Trejo P,Domínguez A,Solari S,Valdivia G,Arteaga E

doi

10.4067/S0034-98872013000100013

subject

Has Abstract

pub_date

2013-01-01 00:00:00

pages

95-103

issue

1

eissn

0034-9887

issn

0717-6163

pii

S0034-98872013000100013

journal_volume

141

pub_type

杂志文章
  • [Current status of cardiac rehabilitation in Chile].

    abstract:BACKGROUND:Cardiac rehabilitation (CR) programs play an important role in the control and prevention of new cardiac events. AIM:A survey was performed to evaluate the current situation of CR programs in Chile. MATERIAL AND METHODS:A questionnaire evaluating the structure of rehabilitation centers, characteristics of ...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章

    doi:10.4067/S0034-98872012000500002

    authors: Santibáñez C,Pérez-Terzic C,López-Jiménez F,Cortés-Bergoderi M,Araya MV,Burdiat G

    更新日期:2012-05-01 00:00:00

  • [Multisystemic involvement in obstructive sleep apnea].

    abstract::Obstructive Sleep Apnea (OSA) is characterized by repetitive upper airway collapse with apnea/hypopnea and recurrent hypoxia during sleep, which results in fragmented sleep and intermittent drops in arterial blood oxygen saturation (hypoxemia). Several dysfunctions of neurocognitive, endocrine, cardiovascular, and met...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章,评审

    doi:10.4067/S0034-98872014000600009

    authors: Labarca G,Cruz N R,Descalzi F

    更新日期:2014-06-01 00:00:00

  • [Prevalence of hepatitis C virus antibodies in a hemodialysis unit].

    abstract::The prevalence of hepatitis C antibody was studied using the EIA 2 Abbott assay in patients and staff of the San Juan de Dios Hospital Hemodialysis Unit. The antibody was detected in 29.8% of patients, no member of the staff had positive antibodies. Patients with a positive antibody had been on hemodialysis for a long...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章

    doi:

    authors: Rodríguez MI,Estay R,Soto JR,Wolff C,Plubins L,Child R,Armas R

    更新日期:1993-02-01 00:00:00

  • [Parental perceptions and expectations about sexual and reproductive health care for urban adolescents].

    abstract:UNLABELLED:Studies have reported which expectations and demands adolescents have for more accessible sexual and reproductive health (SRH) services. However, there is limited information regarding parents' requirements and demands for SRH services their adolescents need. AIM:To explore the knowledge of parents regardin...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章

    doi:10.4067/S0034-98872014001000005

    authors: Luengo-Charath MX,Millán-Klüsse T,Herreros A J,Zepeda O AJ,Henríquez C ME

    更新日期:2014-10-01 00:00:00

  • [The human genome in clinical medicine].

    abstract::A revolution is taking place in Medicine as a consequence of advances in biotechnology and informatics. The unraveling of the human genome with a description of chromosomal maps for all structural genes affords a new framework for the understanding of etiology, diagnosis and prevention of every disease. More than thre...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章,评审

    doi:

    authors: Cruz-Coke R

    更新日期:1989-05-01 00:00:00

  • [Gastric adenocarcinoma appearing 32 years after the resection of a gastric lymphoma. Report of one case].

    abstract::The association of gastric lymphoma and gastric adenocarcinoma in the same patient is uncommon. We report a 76 year-old male with a previous history of massive upper gastrointestinal bleeding who required a subtotal gastrectomy with Billroth II reconstruction in 1974. Pathology demonstrated a gastric lympho-histiocyti...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章

    doi:/S0034-98872008001000013

    authors: Butte JM,Torres J,Duarte I,Guzmán S,Llanos O

    更新日期:2008-10-01 00:00:00

  • [Recent case law about the right to die].

    abstract::This paper reviews the sentences dictated between 1993 and 2002 by the Supreme Courts of Canada and the Unites States, the House of Lords and Supreme Court of the United Kingdom and the European Human Rights Court, about the validity of the legal prohibition of assistance for suicide. These sentences constituted a jud...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章,评审

    doi:10.4067/S0034-98872016000400009

    authors: Bascuñán R A

    更新日期:2016-04-01 00:00:00

  • [Rising infant mortality in down syndrome in Chile from 1997 to 2013].

    abstract:BACKGROUND:Down syndrome (DS) is associated with higher child mortality especially due to cardiac malformations. AIM:To describe the trend in Chilean infant mortality in DS in the period 1997-2013 as compared to the general population without DS. MATERIAL AND METHODS:Raw data on infant deaths were extracted from the ...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章

    doi:10.4067/S0034-98872016001100009

    authors: Donoso E,Vera C

    更新日期:2016-11-01 00:00:00

  • [Teaching of clinical reasoning to medical students using prototypical clinical cases].

    abstract:BACKGROUND:Clinical reasoning is the most important competente in the training process of a physician. AIM:To develop a method for teaching clinical reasoning based on prototypes of clinical cases. MATERIAL AND METHODS:The study was conducted on sixty-four third year medical students. The study and control groups att...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章

    doi:10.4067/S0034-98872013000700001

    authors: Montaldo L G,Herskovic L P

    更新日期:2013-07-01 00:00:00

  • [Prevalence of sexual dysfunction in climacteric women. Influence of menopause and hormone replace therapy].

    abstract:BACKGROUND:Few trials have studied the prevalence of sexual dysfunction (SD) and related risk factors in postmenopausal women using the DSM-IV criteria. AIM:To evaluate the prevalence of SD in menopausal women and the impact of risk factors. PATIENTS AND METHODS:Five hundred thirty four healthy women, 40 to 64 years ...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章

    doi:

    authors: Blümel JE,Araya H,Riquelme R,Castro G,Sánchez F,Gramegna G

    更新日期:2002-10-01 00:00:00

  • [Renal oncocytoma: 4 cases].

    abstract::Oncocytomas are tumors characterized by cells with an eosinophilic cytoplasm. Renal oncocytomas were described in 1942. Among 46 consecutive patients operated on for renal tumors, oncocytomas were found in 4 (8.7%). In spite of a supposedly benign nature, renal oncocytoma cannot be adequately differentiated from renal...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章

    doi:

    authors: Castillo O,van Cauwelaert R,Aguirre C,Arellano L,Medina FJ

    更新日期:1992-05-01 00:00:00

  • [Effect of VKORC1 and CYP2C9 variants on dosage of oral anticoagulants in Chilean individuals].

    abstract:BACKGROUND:The dose of oral anticoagulants (OAC) shows great variability among patients. Pharmacogenetic studies have shown that common variants in genes CYP2C9 (*2 and *3) and VKORC1 (-1639G>A) are associated with lower requirements of OAC. AIM:To study the association between average maintenance doses of oral antico...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章

    doi:10.4067/S0034-98872015001100001

    authors: Benavides F,Grossman N,Poggi H,Nieto E,Bertrán A,Araos D,Vásquez M,Ibarra I,Cáceres F,Espinoza K,Lagos M,Repetto M G

    更新日期:2015-11-01 00:00:00

  • [Development of a professional social responsibility questionnaire for physicians].

    abstract:BACKGROUND:Professional Social Responsibility is now imperative for the practice of medicine. However, there are no instruments to assess it among physicians. AIM:To construct and evaluate the factorial structure and reliability of a questionnaire designed to measure socially responsible behavior in physicians. MATER...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章

    doi:10.4067/S0034-98872014000100014

    authors: Alvarado DF,Pérez CV,Navarro GS

    更新日期:2014-01-01 00:00:00

  • [Nodular goiter recurrent after surgery. A study of its pathogenesis and incidence].

    abstract::We analyzed 33 patients with recurring nodular goiter (from a population of 2,500 operated patients). Recurrence occurred 0.7 to 12 years after surgery. T4, T3, TSH, perchlorate and TRH tests were performed in 18. Results were similar to those in 13 operated patients without recurrence. Administration of thyroid hormo...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章

    doi:

    authors: Villaseca R,López Caffarena E

    更新日期:1990-01-01 00:00:00

  • [Practice of Internal Medicine in Latin America. Role of the internist].

    abstract::This article explores the causes of the crisis in the role of internists. As in the United States, the progressive specialization of internists lead to a dehumanized, expensive and technical practice of medicine. Aiming to better incomes and prestige, more than 60% of internists practice as specialists. Primary care p...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章

    doi:

    authors: Varela N

    更新日期:2002-01-01 00:00:00

  • [Outcome of microbial invasion of amniotic cavity in the preterm premature rupture of membranes].

    abstract:BACKGROUND:Microbial invasion of amniotic cavity occurs in 30 to 50% of patients with premature membrane rupture. AIM:To determine the outcomes associated with microbial invasion of the amniotic cavity (MIAC) in patients with preterm premature rupture of membrane (pPROM). PATIENTS AND METHODS:One hundred thirty four ...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章

    doi:10.4067/s0034-98872005000100007

    authors: Ovalle S A,Gómez M R,Martínez T MA,Kakarieka W E,Fuentes G A,Aspillaga M C,Ferrand M P,Ramírez F C

    更新日期:2005-01-01 00:00:00

  • [Constrictive pericarditis as a serious and rare presentation of systemic lupus erythematosus: Report of one case].

    abstract::Constrictive Pericarditis (CP) is an unusual disease. Its most common causes are idiopathic or secondary to cardiac surgery. Less frequently it is caused by connective tissue diseases. We report a 30 years old woman hospitalized due to progressive dyspnea, chest pain and signs of right sided heart failure. During her ...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章

    doi:10.4067/S0034-98872014000800015

    authors: Lustig N,Florenzano P,Sanhueza LM,Cid X,Ramos G,Thone N,Fullerton DA

    更新日期:2014-08-01 00:00:00

  • [Estimation of the number of institutionalized elderly in Chile].

    abstract:BACKGROUND:Elderly people (>60 years) in Chile represented 11.4% (n=1,717,478) of the total population in 2002. The group with disabilities or mental problems is increasing and there is no reliable information about the number of institutionalized elderly subjects. AIM:To estimate the number of elderly people living i...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章

    doi:10.4067/s0034-98872004000700007

    authors: Marín PP,Guzmán JM,Araya A

    更新日期:2004-07-01 00:00:00

  • [Mushroom poisoning in the IX region. Role of Amanita gemmata].

    abstract::We report four episodes of mushroom poisoning that occurred between 1986 and 1990 in the province of Malleco. Twenty five of 36 individuals who ingested the mushroom became ill; they had an acute gastroenteritis that was followed in 7 by an acute hepatitis and in one by a massive upper gastrointestinal bleeding. Three...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章

    doi:

    authors: Sierralta A,Jeria ME,Figueroa G,Pinto J,Araya JC,San Juan J,Grinbergs J,Valenzuela E

    更新日期:1994-07-01 00:00:00

  • [Commercial reagents in the diagnosis of Chagas' disease].

    abstract::The great diversity of commercially available products for the serologic diagnosis of Chagas disease led us to conduct a study of these products in comparison with the indirect immunofluorescence test. Percent agreement between methods ranged from 79 to 100%, the details for each product being given in the text. Bette...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章

    doi:

    authors: Astorga B,Herskovic P

    更新日期:1990-10-01 00:00:00

  • [Comparative performance of symptoms questionnaire, hydrogen test and genetic test for lactose intolerance].

    abstract:BACKGROUND:Genetically programmed adult-type hypolactasia affects 56% of Chilean population. Ideally, diagnosis should be confirmed. AIM:To compare diagnostic yield of genetic test, hydrogen (H2) expiratory test and a validated symptomatic structured survey (SS). MATERIAL AND METHODS:Patients submitted to H2 test ans...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章

    doi:10.4067/S0034-98872012000900001

    authors: Rollán A,Vial C,Quesada S,Espinoza K,Hatton M,Puga A,Repetto G

    更新日期:2012-09-01 00:00:00

  • [Epigenetics of polycystic ovary syndrome].

    abstract::Polycystic ovarian syndrome (PCOS) is an endocrine and metabolic dysfunction, highly prevalent in women in their reproductive years. Hyperandrogenism, oligo-ovulation, polycystic ovarian morphology are the main features of this syndrome. PCOS is a genetic disorder with a multifactorial etiology and has a strong link w...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章,评审

    doi:10.4067/s0034-98872017000700907

    authors: Concha C F,Sir P T,Recabarren SE,Pérez B F

    更新日期:2017-07-01 00:00:00

  • [A national survey on smoking habit among health care workers in Chile].

    abstract:BACKGROUND:Worldwide, smoking is the main avoidable cause of death among adults. AIM:To study smoking habits among health care workers in Chile. MATERIAL AND METHODS:A national survey about smoking among subjects working in the Chilean Ministry of Health. An anonymous and self administered enquiry was used. RESULTS:...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章

    doi:10.4067/s0034-98872004000200013

    authors: Bello S,Soto M,Michalland S,Salinas J

    更新日期:2004-02-01 00:00:00

  • [Iodine nutrition in school children of four census areas of Chile].

    abstract:BACKGROUND:Although endemic goiter is an easily controlled chronic disease, it continues to be a serious global public health problem. AIM:To study iodine nutrition in school age children from different areas of Chile. SUBJECTS AND METHODS:Thyroid gland was palpated in 4181 school age children from Calama, Santiago, ...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章

    doi:

    authors: Muzzo S,Burgueño M,Carvajal F,Biolley E,Avendaño M,Vargas S,Leiva L

    更新日期:1997-11-01 00:00:00

  • [Trends in current medicine].

    abstract::Predicting the future of medicine is daring. One can speculate about some of its future traits at the most. The spectacular progress in biological sciences has nurtured the hope that medicine will be able to dominate all ailments, improve the quality of life and longevity. Physicians are uncomfortable with the weak kn...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章

    doi:

    authors: Goic A

    更新日期:1999-09-01 00:00:00

  • [Seroepidemiology of Herpes simplex virus type 2 in the Amerindian Yukpa population of Zulia state, Venezuela].

    abstract:BACKGROUND:Yukpa aborigines start early in life their sexual activity and promiscuity with native and foreign individuals is common among women. This behavior allows the installation and propagation of Herpes simplex virus type 2 (HSV-2). AIM:To determine the presence of antibodies to HSV-2 in a Yukpa Amerindian commu...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章

    doi:

    authors: Monsalve F,Estévez J,Costa L,Salas M,Hernández M,Olaya J,Rodríguez E,Callejas D

    更新日期:2001-03-01 00:00:00

  • [Age of menarche and genetic blood markers].

    abstract::In 160 girls from low and middle socio-economic class of Santiago we correlated the age at menarque with genetic markers such as ABO blood group, Rh, MN, Xg, haptoglobins, Esterase D and Phosphoglucomutase. No significant association of these markers and age at menarque was found. ...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章

    doi:

    authors: Valenzuela C,Avendaño A,Huerta J,Wells P,Gana R

    更新日期:1990-07-01 00:00:00

  • [Endoscopy after bariatric surgery: what the endoscopist must know].

    abstract::Endoscopy is essential in the assessment and treatment of the bariatric patient, especially in the postoperative state. Since bariatric surgery is increasing exponentially, endoscopists should be familiar with the anatomy and how to manage possible complications. New less invasive therapeutic tools will have a major i...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章

    doi:10.4067/S0034-98872020000100083

    authors: Díaz R,Narvaez A,Welsh L,Pérez JE,Dávalos G,Portenier D,Guerron AD

    更新日期:2020-01-01 00:00:00

  • [Association between glutathione peroxidase levels and clinical manifestations of dengue].

    abstract:BACKGROUND:Glutathione peroxidase (GP) can be used as a marker of oxidative stress in infectious diseases. AIM:To evaluate the association between the levels of glutathione peroxidase (GP) and the manifestations and complications of dengue. PATIENTS AND METHODS:Between April 2003 and December 2004, 161 patients with ...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章

    doi:10.4067/s0034-98872007000600008

    authors: Rojas EM,Díaz-Quijano FA,Coronel-Ruiz C,Martínez-Vega RA,Rueda E,Villar-Centeno LA

    更新日期:2007-06-01 00:00:00

  • [Prevalence of dental fluorosis in Chile: a pilot study].

    abstract::The prevalence of enamel fluorosis and its severity was studied in 118 young men of 2 socio-economic levels. The subjects were born and resided for at least 6 years in Chilean communities with different natural levels of fluoride in drinking water. There was a high prevalence of enamel defect overall (54%) most of it ...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章

    doi:

    authors: Mella S,Atalah E,Aranda W,Montagna R

    更新日期:1992-08-01 00:00:00