Optogenetics through windows on the brain in the nonhuman primate.

abstract：:Although studies of the principal tongue protrudor muscle genioglossus (GG) suggest that whole muscle GG electromyographic (EMG) activities are preserved in nonrapid eye movement (NREM) sleep, it is unclear what influence sleep exerts on individual GG motor unit (MU) activities. We characterized the firing patterns of...

journal_title：Journal of neurophysiology

authors： Bailey EF,Fridel KW,Rice AD

更新日期：2007-12-01 00:00:00

abstract：:1. Both stretch and release of the ventral superficial muscles (VSM) in the abdomen of the hermit crab, Pagurus pollicarus, activate the VSM motoneurons in the intact animal and in the isolated abdomen. 2. This reflex was studied by recording intracellularly from muscle fibers innervated by single motoneurons during s...

journal_title：Journal of neurophysiology

authors： Chapple WD

更新日期：1993-06-01 00:00:00

abstract：:In acute experiments performed in decerebrated and spinalized (T13) cats, an intraspinal injection of clonidine, a noradrenergic agonist, restricted to mid-lumbar segments L3-L4, can induce hindlimb locomotion, whereas yohimbine, a noradrenergic antagonist, can block spinal locomotion, and a second spinal lesion at L4...

journal_title：Journal of neurophysiology

authors： Langlet C,Leblond H,Rossignol S

更新日期：2005-05-01 00:00:00

abstract：:1. Retzius (R) neurons of the fifth and sixth segmental ganglia of the leech, called R(5,6) neurons are specialized to innervate the adjacent reproductive organs and are morphologically and functionally distinct from R neurons of standard ganglia [R(x) cells]. In this study the electrical properties of the R(x) and R(...

journal_title：Journal of neurophysiology

authors： Merz DC

更新日期：1995-03-01 00:00:00

abstract：:1. Depolarization-induced elevations of intracellular calcium concentration ([Ca2+]i) were examined in slice-cultured hippocampal pyramidal and nonpyramidal cells of the CA3 region by combined intracellular and multisite fura-2 recording techniques. 2. In pyramidal cells, spiking activity induced by depolarizing curre...

journal_title：Journal of neurophysiology

authors： Knöpfel T,Gähwiler BH

更新日期：1992-09-01 00:00:00

abstract：:Intrathecally applied nicotine reduces bradykinin-induced plasma extravasation (BK-induced PE) in the rat knee joint. This depression is mediated by the hypothalamo-pituitary-adrenal (HPA) axis and is enhanced by interruption of impulse traffic in afferents of the abdominal vagus nerve. Like intrathecal nicotine, elec...

journal_title：Journal of neurophysiology

authors： Miao FJ,Jänig W,Green PG,Levine JD

更新日期：1997-09-01 00:00:00

abstract：:In big brown bats, tone-specific plastic changes [best frequency (BF) shifts] of cortical and collicular neurons can be evoked by auditory fear conditioning, repetitive acoustic stimuli or cortical electric stimulation. It has been shown that acetylcholine (ACh) plays an important role in evoking large long-term corti...

journal_title：Journal of neurophysiology

authors： Ji W,Suga N,Gao E

更新日期：2005-08-01 00:00:00

abstract：:Effective connectivity between cortical areas decreases during slow wave sleep. This decline can be observed in the reduced interareal propagation of activity evoked either directly in cortex by transcranial magnetic stimulation (TMS) or by sensory stimulation. We present here a large-scale model of the thalamocortica...

journal_title：Journal of neurophysiology

authors： Esser SK,Hill S,Tononi G

更新日期：2009-10-01 00:00:00

abstract：:We developed a physiologically realistic mathematical model of the Golgi tendon organ (GTO) whose elements correspond to anatomical features of the biological receptor. The mechanical interactions of these elements enable it to capture all salient aspects of GTO afferent behavior reported in the literature. The model ...

journal_title：Journal of neurophysiology

authors： Mileusnic MP,Loeb GE

更新日期：2006-10-01 00:00:00

abstract：:The vestibular system operates in a push-pull fashion using signals from both labyrinths and an intricate bilateral organization. Unilateral vestibular lesions cause well-characterized motor deficits that are partially compensated over time and whose neural correlates have been traced in the mean response modulation o...

journal_title：Journal of neurophysiology

authors： Yu XJ,Thomassen JS,Dickman JD,Newlands SD,Angelaki DE

更新日期：2014-08-15 00:00:00

abstract：:Cellular mechanisms underlying defense reactions induced by noxious heat and acids were studied in frogs (Rana pipiens) by measuring whole cell membrane currents in cultured dorsal root ganglion (DRG) neurons. Seventy-eight of 82 DRG neurons exposed to 3-s ramps of increasing temperature to 48 degrees C exhibited an i...

journal_title：Journal of neurophysiology

authors： Kuffler DP,Lyfenko A,Vyklický L,Vlachová V

更新日期：2002-10-01 00:00:00

abstract：:Olfactory bulb (OB) glomeruli, the initial sites of synaptic processing of odor information, exhibit high levels of nicotinic acetylcholine receptor (nAChR) expression and receive strong cholinergic input from the basal forebrain. The role of glomerular nAChRs in olfactory processing, however, remains to be elucidated...

journal_title：Journal of neurophysiology

authors： D'Souza RD,Parsa PV,Vijayaraghavan S

更新日期：2013-10-01 00:00:00

abstract：:1. Single-unit and multiunit activities were recorded at the area 17-18 border of each cortical hemisphere in paralyzed cats anesthetized with nitrous oxide supplemented with halothane. Cross-correlation histograms (CCHs) were computed between 86 pairs of single units and 99 pairs of multiunit activities. Visually evo...

journal_title：Journal of neurophysiology

authors： Nowak LG,Munk MH,Nelson JI,James AC,Bullier J

更新日期：1995-12-01 00:00:00

abstract：:1. Pharmacologic agents known to modulate long-term potentiation (LTP) at the mossy fiber-to-CA3 pyramidal neuron synapse were tested for their effects on the activity of single voltage-gated calcium channels in adult CA3 pyramidal neurons. 2. Single-channel current recordings of three types of voltage-gated calcium c...

journal_title：Journal of neurophysiology

authors： Fisher R,Johnston D

更新日期：1990-10-01 00:00:00

abstract：:1. In the European rock lobster, Homarus gammarus, two bilaterally symmetrical pairs of commissural neurons, P and commissural pyloric (CP), evoke excitatory postsynaptic potentials in the neurons of the pyloric motor network. The present paper shows that the two commissural neurons also exert a modulatory control ove...

journal_title：Journal of neurophysiology

authors： Nagy F,Cardi P

更新日期：1994-06-01 00:00:00

abstract：:1. We have studied the physiology of sensory neurons innervating skin of the rat hindlimb, in three groups of animals: 1) normal animals; 2) animals in which the sural nerve (Sn) had regenerated to its original cutaneous target; and 3) animals in which the gastrocnemius muscle nerve (Gn) had previously been cut and cr...

journal_title：Journal of neurophysiology

authors： Lewin GR,McMahon SB

更新日期：1991-10-01 00:00:00

abstract：:Connections between layer V pyramidal cells and GABAergic fast-spiking interneurons (pyramidal-FS) were studied by paired recordings combined with morphological analyses in acute neocortical slices from 28- to 52-day-old rats. Pairs of spikes elicited in pyramidal cells at a stimulation rate of 0.2 Hz induced unitary ...

journal_title：Journal of neurophysiology

authors： Angulo MC,Staiger JF,Rossier J,Audinat E

更新日期：2003-02-01 00:00:00

abstract：:1. Effects of inositol-1,4,5-trisphosphate (InsP3) applied through a patch pipette to Xenopus laevis olfactory receptor cells (ORCs) were studied using the patch-clamp technique in conjunction with calcium imaging with fura-2. 2. InsP3 activated, first, a novel voltage-independent Ca2+ current (ICa) and, second, a non...

journal_title：Journal of neurophysiology

authors： Schild D,Lischka FW,Restrepo D

更新日期：1995-02-01 00:00:00

abstract：:We constantly make eye movements to bring objects of interest onto the fovea for more detailed processing. Activity in area V4, a prestriate visual area, is enhanced at the location corresponding to the target of an eye movement. However, the precise role of activity in V4 in relation to these saccades and the modulat...

journal_title：Journal of neurophysiology

authors： Gee AL,Ipata AE,Goldberg ME

更新日期：2010-10-01 00:00:00

abstract：:1. Previous studies indicate that after transection of the rostral spinal cord, larval lamprey begin to recover locomotor behavior 2 wk posttransection and recovery is complete at approximately 8 wk. To examine the mechanisms underlying behavioral recovery after spinal cord transection, in the present study the time c...

journal_title：Journal of neurophysiology

authors： McClellan AD

更新日期：1994-08-01 00:00:00

abstract：:Horseradish peroxidase- (HRP) filled microelectrodes have been used to examine the anatomy and physiology of "commissural interneurons," a morphologically defined class of spinal cord interneuron in Xenopus laevis embryos. Commissural interneurons have unipolar cell bodies in the dorsal half of the spinal cord. Their ...

journal_title：Journal of neurophysiology

authors： Soffe SR,Clarke JD,Roberts A

更新日期：1984-06-01 00:00:00

abstract：:We investigated the cellular mechanism underlying presynaptic regulation of olfactory receptor neuron (ORN) input to the mouse olfactory bulb using optical-imaging techniques that selectively report activity in the ORN presynaptic terminal. First, we loaded ORNs with calcium-sensitive dye and imaged stimulus-evoked ca...

journal_title：Journal of neurophysiology

authors： Wachowiak M,McGann JP,Heyward PM,Shao Z,Puche AC,Shipley MT

更新日期：2005-10-01 00:00:00

abstract：:1. The sensory responsiveness of cells in the inferior olive is known to be suppressed during certain phases of active movement. These experiments were designed to test the possibility that activity in the rubrospinal pathway contributes to this suppression. We recorded from cells sensitive to light touch located in o...

journal_title：Journal of neurophysiology

authors： Weiss C,Houk JC,Gibson AR

更新日期：1990-10-01 00:00:00

abstract：:In mesial temporal lobe (MTL) epilepsy, which typically involves the hippocampus (HPC), epileptiform events are enhanced during slow wave sleep (SWS). It remains unclear how and why the electroencephalographic (EEG) states that constitute SWS might predispose the HPC to this type of pathological activity. Recently our...

journal_title：Journal of neurophysiology

authors： Nazer F,Dickson CT

更新日期：2009-09-01 00:00:00

abstract：:The nucleus of the tractus solitarius (NTS) plays an important role in the control of several autonomic reflex functions and has glutamate and GABA as main neurotransmitters. In this work, we used patch-clamp recordings in transverse slice preparations from rats to study whether the glycine binding site of the N-methy...

journal_title：Journal of neurophysiology

authors： Baptista V,Varanda WA

更新日期：2005-07-01 00:00:00

abstract：:1. Two hundred and twenty-one spinothalamic tract (STT) neurons in the lumbar spinal cord of anesthetized monkeys were studied. The majority of the recordings were in laminae IV-VI. Thirteen of these neurons were intracellularly injected with horseradish peroxidase and histologically reconstructed. 2. A standard serie...

journal_title：Journal of neurophysiology

authors： Surmeier DJ,Honda CN,Willis WD Jr

更新日期：1988-03-01 00:00:00

abstract：:Slowness of voluntary movements in patients with multiple sclerosis (MS) may be due to various factors, including attentional and cognitive deficits, delays in motor conduction time, and impairment of specific central nervous system circuits. In 13 healthy volunteers and 20 mildly disabled, relapsing-remitting MS pati...

journal_title：Journal of neurophysiology

authors： Cabib C,Llufriu S,Casanova-Molla J,Saiz A,Valls-Solé J

更新日期：2015-03-01 00:00:00

abstract：:The aim of this study was to investigate how maximal intermittent contractions for a hand muscle influence cortical and reflex activity, as well as the ability to voluntarily activate, the homologous muscle in the opposite limb. Twelve healthy subjects (age: 24 ± 3 years, all right hand dominant) performed maximal con...

journal_title：Journal of neurophysiology

authors： Kavanagh JJ,Feldman MR,Simmonds MJ

更新日期：2016-11-01 00:00:00

abstract：:The locus coeruleus (LC) noradrenergic (NE) neuromodulatory system is critically involved in regulation of neural excitability via its diffuse ascending projections. Tonic NE release in the forebrain is essential for maintenance of vigilant states and increases the signal-to-noise ratio of cortical sensory responses. ...

journal_title：Journal of neurophysiology

authors： Neves RM,van Keulen S,Yang M,Logothetis NK,Eschenko O

更新日期：2018-03-01 00:00:00

abstract：:1. Hindlimb paw-shake responses were assessed before and after unilateral deafferentation (L3-S1) in chronic-spinal cats (n = 5), spinalized at the T12 level 1 yr earlier. Selected ankle flexor [tibialis anterior (TA)] and extensor [lateral gastrocnemius (LG)] and knee extensor [vastus lateralis (VL)] muscles were sur...

journal_title：Journal of neurophysiology

authors： Koshland GF,Smith JL

更新日期：1989-07-01 00:00:00