Abstract:
AIMS:Hydrogen peroxide (H2 O2 ) disinfection applications are limited by its rapid inactivation. The aims of this study were to (i) micro-encapsulate H2 O2 in silica hydrogels to obtain controlled release up to 72 h, (ii) test hydrogel antimicrobial activity against four common pathogens and (iii) assess H2 O2 release kinetics and antimicrobial activity in 35-65% relative humidity and 37°C to approximate bandaged wound conditions. METHODS AND RESULTS:Hydrogels were characterized using scanning electron microscopy, nitrogen sorption porosimetry, Brunauer Emmet Teller analysis and the Barret-Joyner-Halenda method. Hydrogels formed at lower pH demonstrated increased surface area and decreased pore size, resulting in H2 O2 release lasting 72 h. Using agar well diffusion for antimicrobial activity, statistically significant zones of inhibition (as compared to controls) were seen for Escherichia coli, Staphylococcus aureus, Pseudomona aeruginiosa and Vancomycin-resistant Enterococcus faecalis. Activity remained for hydrogels aged for 72 h in humid, 37°C conditions. CONCLUSIONS:Hydrogels can be synthesized to provide a continuous, controlled release of H2 O2 for up to 72 h. SIGNIFICANCE AND IMPACT OF THE STUDY:Stable, controlled-release H2 O2 hydrogels have potential applications for wound treatment and disinfection of medical equipment, through bonding to bandages or materials such as catheter lumens.
journal_name
J Appl Microbioljournal_title
Journal of applied microbiologyauthors
Dogan-Guner EM,Mohamed H,Orbey N,Goodyear Ndoi
10.1111/jam.14177subject
Has Abstractpub_date
2019-03-01 00:00:00pages
965-972issue
3eissn
1364-5072issn
1365-2672journal_volume
126pub_type
杂志文章abstract:AIM:To determine the structure of the chimeric chromosome X of bottom-fermenting yeasts. METHODS AND RESULTS:Eight cosmid clones carrying DNA from chromosome X of bottom-fermenting yeasts were selected by end-sequencing. Four of the cosmid clones had Saccharomyces cerevisiae (SC)-type and Saccharomyces bayanus (SB)-ty...
journal_title:Journal of applied microbiology
pub_type: 杂志文章
doi:10.1111/j.1365-2672.2009.04289.x
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abstract:AIMS:To describe the occurrence and virulence gene pattern of shiga toxin-producing Escherichia coli (STEC) and enteropathogenic E. coli (EPEC) in healthy goats of Jammu and Kashmir, India. METHODS AND RESULTS:A total of 220 E. coli strains belonging to 60 different 'O' serogroups was isolated from 206 local (nonmigra...
journal_title:Journal of applied microbiology
pub_type: 杂志文章
doi:10.1111/j.1365-2672.2005.02759.x
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abstract:AIMS:In vitro experiments were undertaken to evaluate biocide formulations commonly used in cooling water systems against protozoa previously isolated from cooling towers. The investigations evaluated the efficacy of these formulations against amoebic cysts and trophozoites. METHODS AND RESULTS:Laboratory challenges a...
journal_title:Journal of applied microbiology
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doi:10.1111/j.1365-2672.2008.04044.x
更新日期:2009-03-01 00:00:00
abstract:AIMS:The aim of this study was to characterize anaerobic ammonium oxidation (anammox) community in sediments of the Dongjiang River, a drinking water source of Hong Kong. METHODS AND RESULTS:The diversity and distribution of the anammox community were investigated based on a comparative analyses of 16S rRNA and hydraz...
journal_title:Journal of applied microbiology
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journal_title:Journal of applied microbiology
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doi:10.1111/jam.13543
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journal_title:Journal of applied microbiology
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更新日期:2000-09-01 00:00:00
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journal_title:Journal of applied microbiology
pub_type: 杂志文章
doi:10.1111/jam.14701
更新日期:2020-11-01 00:00:00
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journal_title:Journal of applied microbiology
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更新日期:2002-01-01 00:00:00
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journal_title:Journal of applied microbiology
pub_type: 杂志文章
doi:10.1111/jam.12576
更新日期:2014-09-01 00:00:00
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journal_title:Journal of applied microbiology
pub_type: 杂志文章
doi:10.1046/j.1365-2672.2001.01263.x
更新日期:2001-03-01 00:00:00
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journal_title:Journal of applied microbiology
pub_type: 杂志文章
doi:10.1111/jam.12051
更新日期:2013-02-01 00:00:00
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journal_title:Journal of applied microbiology
pub_type: 杂志文章
doi:10.1111/j.1365-2672.2007.03468.x
更新日期:2007-12-01 00:00:00
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pub_type: 杂志文章
doi:10.1111/j.1365-2672.2009.04493.x
更新日期:2010-03-01 00:00:00
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journal_title:Journal of applied microbiology
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doi:10.1111/jam.13589
更新日期:2018-02-01 00:00:00
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journal_title:Journal of applied microbiology
pub_type: 杂志文章,评审
doi:10.1046/j.1365-2672.1999.00872.x
更新日期:1999-08-01 00:00:00
abstract:AIMS:To develop qPCR broad-spectrum primers combined with a Nocardia genus-specific probe for the identification of a broad spectrum of Nocardia spp. and to analyse the effects of using this developed primer and probe set on the ability to quantify Nocardia spp. in mixed DNA. METHODS AND RESULTS:The consequences of us...
journal_title:Journal of applied microbiology
pub_type: 杂志文章
doi:10.1111/jam.13311
更新日期:2017-01-01 00:00:00
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journal_title:Journal of applied microbiology
pub_type: 杂志文章
doi:10.1111/j.1365-2672.2007.03515.x
更新日期:2007-12-01 00:00:00
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journal_title:Journal of applied microbiology
pub_type: 杂志文章
doi:10.1111/j.1365-2672.2007.03309.x
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journal_title:Journal of applied microbiology
pub_type: 杂志文章
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journal_title:Journal of applied microbiology
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doi:10.1111/jam.12981
更新日期:2016-01-01 00:00:00
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journal_title:Journal of applied microbiology
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更新日期:2017-10-01 00:00:00
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journal_title:Journal of applied microbiology
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更新日期:2008-12-01 00:00:00
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journal_title:Journal of applied microbiology
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doi:10.1111/jam.13913
更新日期:2018-09-01 00:00:00
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journal_title:Journal of applied microbiology
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更新日期:2009-07-01 00:00:00
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journal_title:Journal of applied microbiology
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更新日期:2005-01-01 00:00:00
abstract::Thirty isolates of Listeria monocytogenes and 18 of L. innocua obtained from different short-ripened cheeses manufactured in Asturias (northern Spain), were compared with each other and with reference strains using serotype, phage type and pulsed-field restriction endonuclease digestion profiles analysis of the total ...
journal_title:Journal of applied microbiology
pub_type: 杂志文章
doi:10.1046/j.1365-2672.1998.00339.x
更新日期:1998-02-01 00:00:00
abstract:AIMS:The growth and survival of Staphylococcus xylosus and Staphylococcus carnosus were monitored during sausage manufacture in two processing plants. METHODS AND RESULTS:The gram-positive, catalase-positive cocci isolated from the processing plants F10 and F11 were identified by Staphylococcus-specific PCR and specie...
journal_title:Journal of applied microbiology
pub_type: 杂志文章
doi:10.1111/j.1365-2672.2006.03041.x
更新日期:2007-01-01 00:00:00
abstract:AIMS:Salmonella Typhimurium DT 104 is generally assumed to be spread by contact between live animals, e.g. by trading. The aim of the present study was to assess the importance of other routes of transmission in the dissemination of this bacterium. METHODS AND RESULTS:An outbreak among 14 cattle and pig herds located ...
journal_title:Journal of applied microbiology
pub_type: 杂志文章
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更新日期:2006-10-01 00:00:00
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更新日期:2008-03-01 00:00:00