Retinal periphlebitis is associated with multiple sclerosis severity.

abstract：:Pearson syndrome is a systemic disorder of oxidative phosphorylation in infants, predominantly affecting the bone marrow and exocrine pancreas and associated with single deletions in mitochondrial DNA (mtDNA). CNS involvement may occur in patients who survive the infantile hematopoietic disorder. We describe a Pearson...

journal_title：Neurology

authors： Santorelli FM,Barmada MA,Pons R,Zhang LL,DiMauro S

更新日期：1996-11-01 00:00:00

abstract：:Recurrent episodes of oscillopsia, rotational vertigo, and postural imbalance were elicited and modulated by changing the horizontal head positions of a patient with an arachnoid cyst in the right cerebellopontine angle that distorted the vestibulocochlear nerve. Oculomotor analysis revealed two different types of att...

journal_title：Neurology

authors： Arbusow V,Strupp M,Dieterich M,Jäger L,Hischa A,Schulz P,Brandt T

更新日期：1998-11-01 00:00:00

abstract：:We administered the Mini-Mental State Exam (MMSE) to 194 healthy men and women, ages 40 to 89 years. Total score was significantly associated with age (p less than 0.0001), but not vocabulary, education, Beck's Depression Inventory Score, or sex. The lowest quartile cutoff scores for the MMSE by decade were 40s - 29; ...

journal_title：Neurology

authors： Bleecker ML,Bolla-Wilson K,Kawas C,Agnew J

更新日期：1988-10-01 00:00:00

abstract：:Cytokines such as interleukin-1 and tumor necrosis factor are involved in the triggering of the immune response, induction of acute inflammatory events, and transition to, or persistence of, chronic inflammation. The action of proinflammatory cytokines is regulated by their receptor expression, downregulation and shed...

journal_title：Neurology

authors： Burger D,Dayer JM

更新日期：1995-06-01 00:00:00

abstract：:This is a case study of a patient with the clinical diagnosis of meningoencephalitis. It demonstrates the in vivo development of plasma cells in the central nervous system. All the stages of in vitro mitogen-induced lymphocyte transformation previously described by light and electron microscopy are recapitulated in th...

journal_title：Neurology

authors： Glasser L,Payne C,Corrigan JJ Jr

更新日期：1977-05-01 00:00:00

abstract：:The incidence of MS in the Orkney Islands has been updated from 1941 to September 21, 1983. Since 1965, MS incidence rates have fallen significantly when compared with those for 1941 to 1964. Alterations in age-specific prevalence, mean duration of illness, and mean age of the MS population are consistent with the dec...

journal_title：Neurology

authors： Cook SD,Cromarty JI,Tapp W,Poskanzer D,Walker JD,Dowling PC

更新日期：1985-04-01 00:00:00

abstract：OBJECTIVE:To analyze the oral motor, speech, and language phenotype in 20 children and adults with Dravet syndrome (DS) associated with mutations in SCN1A. METHODS:Fifteen verbal and 5 minimally verbal DS patients with SCN1A mutations (aged 15 months-28 years) underwent a tailored assessment battery. RESULTS:Speech w...

journal_title：Neurology

authors： Turner SJ,Brown A,Arpone M,Anderson V,Morgan AT,Scheffer IE

更新日期：2017-02-21 00:00:00

abstract：:The authors studied presymptomatic individuals with the Huntington disease (HD) mutation to determine whether cortical thinning was present. They found thinning that was regionally selective, semi-independent of striatal volume loss, and correlated with cognitive performance. Early, extensive cortical involvement occu...

journal_title：Neurology

authors： Rosas HD,Hevelone ND,Zaleta AK,Greve DN,Salat DH,Fischl B

更新日期：2005-09-13 00:00:00

abstract：:The rate of spontaneous resolution of a recently diagnosed solitary cerebral cysticercus granuloma as visualized on CT scan was prospectively studied in 210 patients presenting with seizures. The proportion of granulomas that had resolved completely at different time intervals after the index scan was 18.8% at 3 month...

journal_title：Neurology

authors： Rajshekhar V

更新日期：2001-12-26 00:00:00

abstract：:Eighteen patients with congenital nystagmus were studied with the techniques of electronystagmography and computer analysis. We found several complex wave forms of congenital nystagmus in the primary position of gaze above those of jerk and pendular nystagmus as defined clinically. An etiologic classification of motor...

journal_title：Neurology

authors： Yee RD,Wong EK,Baloh RW,Honrubia V

更新日期：1976-04-01 00:00:00

abstract：OBJECTIVES:Assuming the involvement of homocysteine in a generalized small-vessel disease, we investigated the association of homocysteine levels with progression of white matter lesions, lacunar infarcts, and kidney disease. METHODS:Within the SMART-MR (Second Manifestations of ARTerial disease-Magnetic Resonance) St...

journal_title：Neurology

authors： Kloppenborg RP,Geerlings MI,Visseren FL,Mali WP,Vermeulen M,van der Graaf Y,Nederkoorn PJ,SMART Study Group.

更新日期：2014-03-04 00:00:00

abstract：:Among 22 patients with human T-lymphotropic virus type I (HTLV-I)-associated chronic progressive myelopathy, agarose isoelectric focusing (AIF) revealed oligoclonal IgG bands in 21: in 3 in CSF only; in 11 in CSF and to some extent in serum; and in 7, identical patterns in CSF and serum. By immunoblot after AIF of CSF...

journal_title：Neurology

authors： Link H,Cruz M,Gessain A,Gout O,de Thé G,Kam-Hansen S

更新日期：1989-12-01 00:00:00

abstract：:The excitability of the corticospinal system was studied in 23 healthy subjects in sleep stages NREM2, NREM4, REM, and wakefulness using transcranial magnetic stimulation. Assessment of motor thresholds, stimulus-response curves, and latencies of motor evoked potentials shows activation of the fast-conducting corticos...

journal_title：Neurology

authors： Grosse P,Khatami R,Salih F,Kühn A,Meyer BU

更新日期：2002-12-24 00:00:00

abstract：:We report a patient with unusual MRI abnormalities that had the physical characteristics of ferromagnetic artifact. We believe that the MRI artifacts were due to microscopic embolic metal fragments, most likely from a mechanical heart valve prosthesis. Potential sources of metal emboli should be considered in patients...

journal_title：Neurology

authors： Wingerchuk DM,Krecke KN,Fulgham JR

更新日期：1997-11-01 00:00:00

abstract：OBJECTIVE:To investigate the role of multiple distributed brain networks, including the default mode, fronto-temporo-parietal, and cingulo-opercular networks, which mediate domain-general and task-specific processes during speech production after aphasic stroke. METHODS:We conducted an observational functional MRI stu...

journal_title：Neurology

authors： Geranmayeh F,Leech R,Wise RJS

更新日期：2016-04-05 00:00:00

abstract：:Concepts of pathogenesis in Parkinson's disease (PD) have been based on attempts to understand the mechanisms responsible for nigral dopaminergic cell death. Pathogenesis has been proposed to involve oxidative and nitrative stress, excitotoxicity, inflammation, mitochondrial dysfunction, and altered proteolysis. These...

journal_title：Neurology

authors： Jenner P,Olanow CW

更新日期：2006-05-23 00:00:00

abstract：OBJECTIVE:To assess the clinical relevance of a positive voltage-gated potassium channel (VGKC) test in patients lacking antibodies to LGI1 and Caspr2. METHODS:VGKC-positive patients were tested for LGI1 and Caspr2 antibodies. Patients lacking both antibodies were matched (1:2) to VGKC-negative patients. Clinical and ...

journal_title：Neurology

authors： van Sonderen A,Schreurs MW,de Bruijn MA,Boukhrissi S,Nagtzaam MM,Hulsenboom ES,Enting RH,Thijs RD,Wirtz PW,Sillevis Smitt PA,Titulaer MJ

更新日期：2016-05-03 00:00:00

abstract：OBJECTIVE:To investigate the lateralization and localization of ictal EEG in focal epilepsy. METHODS:A total of 486 ictal EEG of 72 patients with focal epilepsy arising from the mesial temporal, neocortical temporal, mesial frontal, dorsolateral frontal, parietal, and occipital regions were analyzed. RESULTS:Surface ...

journal_title：Neurology

authors： Foldvary N,Klem G,Hammel J,Bingaman W,Najm I,Lüders H

更新日期：2001-12-11 00:00:00

abstract：:Recent positive trials have thrust acute cerebral perfusion imaging into the routine evaluation of acute ischemic stroke. Updated guidelines state that in patients with anterior circulation large vessel occlusions presenting beyond 6 hours from time last known well, advanced imaging selection including perfusion-based...

journal_title：Neurology

authors： Vagal A,Wintermark M,Nael K,Bivard A,Parsons M,Grossman AW,Khatri P

更新日期：2019-11-12 00:00:00

abstract：OBJECTIVE:It has been suggested that anemia may be a risk factor for dementia, for restless legs syndrome, and for Parkinson disease (PD). Thus, we investigated the association of anemia with the subsequent risk of PD using a case-control study design. METHODS:We used the medical records-linkage system of the Rocheste...

journal_title：Neurology

authors： Savica R,Grossardt BR,Carlin JM,Icen M,Bower JH,Ahlskog JE,Maraganore DM,Steensma DP,Rocca WA

更新日期：2009-10-27 00:00:00

abstract：OBJECTIVE:To assess the inpatient hospitalization burden and costs of patients with autoimmune encephalitis (AE) at a tertiary care institution. METHODS:Adult inpatients with AE were identified retrospectively from July 1, 2005, to June 30, 2015. Demographic and clinical data were collected and analyzed. Billing data ...

journal_title：Neurology

authors： Cohen J,Sotoca J,Gandhi S,Yeshokumar AK,Gordon-Lipkin E,Geocadin RG,Frick KD,Probasco JC,Venkatesan A

更新日期：2019-02-26 00:00:00

abstract：OBJECTIVE:To evaluate the area of the midbrain and pons on mid-sagittal MRI in patients with progressive supranuclear palsy (PSP), Parkinson disease (PD), and multiple-system atrophy of the Parkinson type (MSA-P), compare these appearances and values with those of normal control subjects, and establish diagnostic MRI c...

journal_title：Neurology

authors： Oba H,Yagishita A,Terada H,Barkovich AJ,Kutomi K,Yamauchi T,Furui S,Shimizu T,Uchigata M,Matsumura K,Sonoo M,Sakai M,Takada K,Harasawa A,Takeshita K,Kohtake H,Tanaka H,Suzuki S

更新日期：2005-06-28 00:00:00

abstract：OBJECTIVE:To identify the source of delayed visual evoked potential (VEP) latencies in the fellow eyes of patients with optic neuritis (ON) and determine whether these latencies stem from clinically silent demyelination or reflect an adaptive process for synchronization with the affected eyes. METHODS:The study sample...

journal_title：Neurology

authors： Raz N,Chokron S,Ben-Hur T,Levin N

更新日期：2013-08-20 00:00:00

abstract：BACKGROUND:TCH346 exerts antiapoptotic effects by binding to glyceraldehyde 3-phosphate dehydrogenase (GAPDH) and blocking the apoptotic pathway in which GAPDH is involved. Apoptosis is considered to be a key pathogenic mechanism in neurodegenerative diseases including ALS. METHODS:Patients were randomly assigned in a...

journal_title：Neurology

authors： Miller R,Bradley W,Cudkowicz M,Hubble J,Meininger V,Mitsumoto H,Moore D,Pohlmann H,Sauer D,Silani V,Strong M,Swash M,Vernotica E,TCH346 Study Group.

更新日期：2007-08-21 00:00:00

abstract：OBJECTIVE:Myelin oligodendrocyte glycoprotein-immunoglobulin G (MOG-IgG) associated disorder (MOGAD) often manifests with recurrent CNS demyelinating attacks. The optimal treatment for reducing relapses is unknown. To help determine the efficacy of long-term immunotherapy in preventing relapse in patients with MOGAD, w...

journal_title：Neurology

authors： Chen JJ,Flanagan EP,Bhatti MT,Jitprapaikulsan J,Dubey D,Lopez Chiriboga ASS,Fryer JP,Weinshenker BG,McKeon A,Tillema JM,Lennon VA,Lucchinetti CF,Kunchok A,McClelland CM,Lee MS,Bennett JL,Pelak VS,Van Stavern G,Adesina

更新日期：2020-07-14 00:00:00

abstract：OBJECTIVE:To present the current terminology and natural history of neurofibromatosis 1 (NF1) cutaneous neurofibromas (cNF). METHODS:NF1 experts from various research and clinical backgrounds reviewed the terms currently in use for cNF as well as the clinical, histologic, and radiographic features of these tumors usin...

journal_title：Neurology

authors： Ortonne N,Wolkenstein P,Blakeley JO,Korf B,Plotkin SR,Riccardi VM,Miller DC,Huson S,Peltonen J,Rosenberg A,Carroll SL,Verma SK,Mautner V,Upadhyaya M,Stemmer-Rachamimov A

更新日期：2018-07-10 00:00:00

abstract：:A 25-year-old man with a long history of temporal lobe epilepsy developed right occipital lobe seizures and a progressive right homonymous hemianopia. MRI showed diffuse enhancement of the left temporoparieto-occipital white matter and cortical thickening of the left medial temporal lobe. The resected temporal lobe re...

journal_title：Neurology

authors： Thom M,Moran NF,Plant GT,Stevens JM,Scaravilli F

更新日期：1999-02-01 00:00:00

abstract：:Study of diagnostic practice is necessary to optimize neurologists' clinical performance and ensure patient safety. To our knowledge, this report is the first set of systematic observations of diagnostic practices of community neurologists in their clinics. The study consisted of six 2-week periods of in situ observat...

journal_title：Neurology

authors： Dhand A,Engstrom J,Dhaliwal G

更新日期：2013-10-15 00:00:00

abstract：OBJECTIVE:To determine the current best practice for treatment of infantile spasms in children. METHODS:Database searches of MEDLINE from 1966 and EMBASE from 1980 and searches of reference lists of retrieved articles were performed. Inclusion criteria were the documented presence of infantile spasms and hypsarrhythmi...

journal_title：Neurology

authors： Mackay MT,Weiss SK,Adams-Webber T,Ashwal S,Stephens D,Ballaban-Gill K,Baram TZ,Duchowny M,Hirtz D,Pellock JM,Shields WD,Shinnar S,Wyllie E,Snead OC 3rd,American Academy of Neurology.,Child Neurology Society.

更新日期：2004-05-25 00:00:00

abstract：BACKGROUND:Evidence linking APOE to myelin repair, neuronal plasticity, and cerebral inflammatory processes suggests that it may be relevant in multiple sclerosis (MS). The purpose of this study was to determine whether the epsilon4 allele of APOE is associated with cognitive deficits in patients with MS. METHOD:Using...

journal_title：Neurology

authors： Ghaffar O,Reis M,Pennell N,O'Connor P,Feinstein A

更新日期：2010-05-18 00:00:00