A life-style physical activity intervention and the antibody response to pneumococcal vaccination in women.


OBJECTIVE:To assess whether a life-style physical activity intervention improved antibody response to a pneumococcal vaccination in sedentary middle-aged women. METHODS:Eighty-nine sedentary women completed a 16-week exercise (physical activity consultation, pedometer, telephone/e-mail prompts; n = 44) or control (advisory leaflet; n = 45) intervention. Pneumococcal vaccination was administered at 12 weeks, and antibody titers (11 of the 23 contained in the pneumococcal vaccine) were determined before vaccination and 4 weeks and 6 months later. Physical activity, aerobic fitness, body composition, and psychological factors were measured before and after the intervention. RESULTS:The intervention group displayed a greater increase in walking behavior (from mean [standard deviation] = 82.16 [90.90] to 251.87 [202.13]) compared with the control condition (111.67 [94.64] to 165.16 [117.22]; time by group interaction: F(1,68) = 11.25, p = .001, η(2) = 0.14). Quality of life also improved in the intervention group (from 19.37 [3.22] to 16.70 [4.29]) compared with the control condition (19.97 [4.22] to 19.48 [5.37]; time by group interaction: F(1,66) = 4.44, p = .039, η(2) = 0.06). However, no significant effects of the intervention on antibody response were found (time by group η(2) for each of the 11 pneumococcal strains ranged from 0.001 to 0.018; p values all >.264). CONCLUSIONS:Participation in a life-style physical activity intervention increased subjective and objective physical activity levels and quality of life but did not affect antibody response to pneumococcal vaccination.


Psychosom Med


Psychosomatic medicine


Long JE,Ring C,Bosch JA,Eves F,Drayson MT,Calver R,Say V,Allen D,Burns VE




Has Abstract


2013-10-01 00:00:00














  • Self-reported depressive symptoms and stress levels in healthy young men: associations with the cortisol response to awakening.

    abstract:OBJECTIVE:There is evidence that clinical depression and negative mood are associated with elevated basal cortisol levels. Recently, measuring the cortisol response during the first hour in the morning with strict reference to the time of awakening was established as a reliable marker of individual adrenocortical activ...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章


    authors: Pruessner M,Hellhammer DH,Pruessner JC,Lupien SJ

    更新日期:2003-01-01 00:00:00

  • Momentary work worries, marital disclosure, and salivary cortisol among parents of young children.

    abstract:OBJECTIVE:To investigate whether worries about work are linked to people's own cortisol levels and their spouses' cortisol levels in everyday life and whether marital factors may moderate these links. Although research has shown that satisfying marriages can buffer the physiological effects of everyday stress, the spec...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章


    authors: Slatcher RB,Robles TF,Repetti RL,Fellows MD

    更新日期:2010-11-01 00:00:00

  • Differential predictive value of depressive versus anxiety symptoms in the prediction of 8-year mortality after acute coronary syndrome.

    abstract:OBJECTIVE:Both depression and anxiety have been associated with poor prognosis in patients with acute coronary syndrome (ACS). However, certain symptoms and how they are measured may be more important than others. We investigated three different scales to determine their predictive validity. METHODS:Patients with ACS ...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章


    authors: Doyle F,Conroy R,McGee H

    更新日期:2012-09-01 00:00:00

  • Predictability, attentional focus, sex role orientation, and menstrual-related stress.

    abstract::Two separate studies assessed the influence on menstrual distress and related inhibition of such variables as predictability of onset, dispositional susceptibility to cultural expectations, and the attentional focus provided by labels. Greater predictability of onset was associated with more positive feedlings about m...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章


    authors: Chernovetz ME,Jones WH,Hansson RO

    更新日期:1979-08-01 00:00:00

  • Presidential Address-1976. Social support as a moderator of life stress.

    abstract::Social support is defined as information leading the subject to believe that he is cared for and loved, esteemed, and a member of a network of mutual obligations. The evidence that supportive interactions among people are protective against the health consequences of life stress is reviewed. It appears that social sup...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章


    authors: Cobb S

    更新日期:1976-09-01 00:00:00

  • Hypothalamic-pituitary-adrenal axis reactivity in chronic fatigue syndrome and health under psychological, physiological, and pharmacological stimulation.

    abstract:OBJECTIVES:Subtle alterations of the hypothalamic-pituitary-adrenal (HPA) axis in chronic fatigue syndrome (CFS) have been proposed as a shared pathway linking numerous etiological and perpetuating processes with symptoms and observed physiological abnormalities. Because the HPA axis is involved in the adaptive respons...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章


    authors: Gaab J,Hüster D,Peisen R,Engert V,Heitz V,Schad T,Schürmeyer TH,Ehlert U

    更新日期:2002-11-01 00:00:00

  • The association of peripheral arterial disease with hostility in a young, healthy veteran population.

    abstract::The association of peripheral arterial disease (PAD) with hostility, a component of Type A behavior, has not been investigated. Previous studies have found an association between coronary arterial disease and hostility. We used Doppler tests to define PAD as consisting of a resting index less than 0.9, absence of post...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章


    authors: Joesoef MR,Wetterhall SF,DeStefano F,Stroup NE,Fronek A

    更新日期:1989-05-01 00:00:00

  • Childhood Cognitive Ability and Age-Related Changes in Physical Capability From Midlife: Findings From a British Birth Cohort Study.

    abstract:OBJECTIVE:The aim of the study was to test the hypothesis that higher childhood cognitive ability is associated with reduced risk of decline in physical capability in late midlife. METHODS:Participants were 1954 men and women from the Medical Research Council National Survey of Health and Development with complete dat...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章


    authors: Cooper R,Richards M,Kuh D

    更新日期:2017-09-01 00:00:00

  • Self-Help for Medically Unexplained Symptoms: A Systematic Review and Meta-Analysis.

    abstract:OBJECTIVE:Medically unexplained symptoms (MUS), which are highly prevalent in all fields of medicine, are considered difficult to treat. The primary objective of this systematic review and meta-analysis was to assess the efficacy of self-help for adults with MUS. METHODS:Four electronic databases were searched for rel...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章,meta分析,评审


    authors: van Gils A,Schoevers RA,Bonvanie IJ,Gelauff JM,Roest AM,Rosmalen JG

    更新日期:2016-07-01 00:00:00

  • Low Control and High Demands at Work as Risk Factors for Suicide: An Australian National Population-Level Case-Control Study.

    abstract:OBJECTIVE:Previous research suggests that psychosocial job stressors may be plausible risk factors for suicide. This study assessed the relationship between psychosocial job stressors and suicide mortality across the Australian population. METHODS:We developed a job exposure matrix to objectively measure job stressors...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章


    authors: Milner A,Spittal MJ,Pirkis J,Chastang JF,Niedhammer I,LaMontagne AD

    更新日期:2017-04-01 00:00:00

  • Impact of Wartime Stress Exposures and Mental Health on Later-Life Functioning and Disability in Vietnam-Era Women Veterans: Findings From the Health of Vietnam-Era Women's Study.

    abstract:OBJECTIVE:The effect of stress exposures and mental health sequelae on health-related outcomes is understudied among older women veterans. We examined a) the impact of wartime stress exposures on later-life functioning and disability in Vietnam-era women veterans and b) the extent to which mental health conditions know...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章


    authors: Smith BN,Spiro A,Frayne SM,Kimerling R,Cypel Y,Reinhard MJ,Kilbourne AM,Magruder KM

    更新日期:2020-02-01 00:00:00

  • Evidence of early retinal microvascular changes in patients with type 2 diabetes and depression.

    abstract:OBJECTIVE:To examine retinal vascular caliber, an indicator of early microvascular disease and depression in patients with Type 2 diabetes. METHODS:We conducted a clinic-based study, comparing participants with Type 2 diabetes with major depression (n = 43), without depression (n = 49), and healthy controls without di...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章


    authors: Nguyen TT,Wong TY,Islam FM,Hubbard L,Ajilore O,Haroon E,Darwin C,Esser B,Kumar A

    更新日期:2010-07-01 00:00:00

  • Respiratory airway changes in response to suggestion in normal individuals.

    abstract::Thirty normal individuals were told they were inhaling a substance that would either cause breathing difficulty (N = 15) or not affect breathing (N = 15). Total respiratory resistance was measured prior to and during inhalation. In reality, the subjects inhaled no substance; inhalation consisted of breathing normally ...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章


    authors: Kotses H,Rawson JC,Wigal JK,Creer TL

    更新日期:1987-09-01 00:00:00

  • Parental history of hypertension and coping responses predict blood pressure changes in black college volunteers undergoing a speaking task about perceptions of racism.

    abstract:OBJECTIVE:This investigation explored the relationship of coping responses and parental history of hypertension to task-induced blood pressure changes. MATERIALS AND METHODS:The sample consisted of 215 black college student volunteers (median age = 25.95 y). During the speaking task, participants responded to standard...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章


    authors: Clark R

    更新日期:2003-11-01 00:00:00

  • Longitudinal study of the impact of psychological distress symptoms on new-onset upper gastrointestinal symptoms in World Trade Center responders.

    abstract:OBJECTIVES:Research on the health of workers involved in the cleanup after the attack on the World Trade Center (WTC) on September 11, 2001, has documented high rates of psychological distress and upper gastrointestinal (GI) symptoms. The current article examines the concurrent and longitudinal associations of psycholo...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章


    authors: Litcher-Kelly L,Lam Y,Broihier JA,Brand DL,Banker SV,Kotov R,Bromet E,Bucobo JC,Shaw RD,Luft BJ

    更新日期:2014-11-01 00:00:00

  • Cortisol levels and responses to mammography screening in breast cancer survivors: a pilot study.

    abstract:OBJECTIVE:The purpose of this study was to compare baseline levels of salivary cortisol, diurnal cortisol slopes, and cortisol reactivity to a mammogram in breast cancer survivors and women without a history of cancer. METHODS:Participants were 33 breast cancer survivors (3-5 years postdiagnosis) and 21 women with no ...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章


    authors: Porter LS,Mishel M,Neelon V,Belyea M,Pisano E,Soo MS

    更新日期:2003-09-01 00:00:00

  • Joint effect of hostility and severity of depressive symptoms on plasma interleukin-6 concentration.

    abstract:OBJECTIVE:Although interleukin (IL)-6 plays a significant role in cardiovascular disease, little is known about its relation to psychological risk factors, such as hostility and severity of depressive symptoms. The current study examined the joint effects of severity of depressive symptoms and hostility on plasma IL-6 ...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章


    authors: Suarez EC

    更新日期:2003-07-01 00:00:00

  • Cynicism and paranoid alienation in the Cook and Medley HO Scale.

    abstract::Factor analysis of responses from 1002 men and women were used to define two subscales of the Cook and Medley Hostility Scale. Both the Cynicism and the Paranoid Alienation subscale described attitudes of mistrust and alienation, and both were correlated with MMPI factors measuring aspects of psychopathology. It was s...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章


    authors: Costa PT Jr,Zonderman AB,McCrae RR,Williams RB Jr

    更新日期:1986-03-01 00:00:00

  • Understanding the Gut Microbiota in Inflammatory and Functional Gastrointestinal Diseases.

    abstract:OBJECTIVE:During the last decade, experimental and observational studies have shown that patients with inflammatory bowel disease (IBD) and irritable bowel syndrome (IBS) may have an altered intestinal microbial composition compared with healthy individuals. However, no uniform microbial signature has as yet been detec...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章,评审


    authors: Sundin J,Öhman L,Simrén M

    更新日期:2017-10-01 00:00:00

  • Stress vulnerability during adolescence: comparison of chronic stressors in adolescent and adult rats.

    abstract:OBJECTIVE:This study investigated the physiological and somatic changes evoked by daily exposure to the same type of stressor (homotypic) or different aversive stressor stimuli (heterotypic) in adolescent and adult rats, with a focus on cardiovascular function. The long-term effects of stress exposure during adolescenc...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章


    authors: Duarte JO,Cruz FC,Leão RM,Planeta CS,Crestani CC

    更新日期:2015-02-01 00:00:00

  • Long-term effects of a complex behavioral treatment of essential hypertension.

    abstract::A multidimensional behavioral program was developed for the treatment of essential hypertension. Over a course of 6 weeks, 108 patients of a rehabilitation center were treated with this program consisting of health education, self-monitoring of blood pressure, relaxation techniques, and a social skill training in addi...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章


    authors: Lehnert H,Kaluza K,Vetter H,Losse H,Dorst K

    更新日期:1987-07-01 00:00:00

  • Cultural models and somatic syndromes.

    abstract:OBJECTIVES:To review the relevance of cultural models in the generation and amplification of somatic symptoms and syndromes. METHODS:Based on a selective review of literature, we examine evidence that cultural and personal explanatory models can contribute to the pathogenesis, symptomatology, and chronicity of medical...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章,评审


    authors: Kirmayer LJ,Sartorius N

    更新日期:2007-12-01 00:00:00

  • Life stresses and premature labor: real connection or artifactual findings?

    abstract::Three studies on the relationship between life stresses and premature labor were conducted. The first was a retrospective comparison of life events between a group of women who had had premature labor and a group of controls. It was carried out between 3 and 6 months after the premature delivery to neutralize possible...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章


    authors: Omer H,Friedlander D,Palti Z,Shekel I

    更新日期:1986-05-01 00:00:00

  • Perceived Discrimination and Longitudinal Change in Kidney Function Among Urban Adults.

    abstract:OBJECTIVE:Perceived discrimination has been associated with psychosocial distress and adverse health outcomes. We examined associations of perceived discrimination measures with changes in kidney function in a prospective cohort study, the Healthy Aging in Neighborhoods of Diversity across the Life Span. METHODS:Our s...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章


    authors: Beydoun MA,Poggi-Burke A,Zonderman AB,Rostant OS,Evans MK,Crews DC

    更新日期:2017-09-01 00:00:00

  • Increased affective bias revealed using experimental graded heat stimuli in young depressed adults: evidence of "emotional allodynia".

    abstract:OBJECTIVE:To examine the hypothesis that young adults with major depressive disorder (MDD) would show increased affective bias to painful and nonpainful experimental heat stimuli, as evidenced by an increased responsiveness to warm and hot temperatures. Pain and depression often occur together. Pain is both a sensation...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章


    authors: Strigo IA,Simmons AN,Matthews SC,Craig AD,Paulus MP

    更新日期:2008-04-01 00:00:00

  • Patterning of cognitive and somatic processes in the self-regulation of anxiety: effects of meditation versus exercise.

    abstract::Davidson and Schwartz (1) have proposed a psychobiological analysis of anxiety that emphasizes the patterning of multiple processes in the generation and self-regulation of this state. The present article specifically reviews recent research on cognitive and somatic components of anxiety. A dual component scale which ...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章


    authors: Schwartz GE,Davidson RJ,Goleman DJ

    更新日期:1978-06-01 00:00:00

  • Chronic interpersonal stress predicts activation of pro- and anti-inflammatory signaling pathways 6 months later.

    abstract:OBJECTIVE:To understand the mechanisms underlying chronic interpersonal difficulties and their detrimental influence on mental and physical health. METHODS:A total of 103 healthy young women (mean age = 17 years) were administered a structured interview to assess the degree of chronic interpersonal stress in their liv...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章


    authors: Miller GE,Rohleder N,Cole SW

    更新日期:2009-01-01 00:00:00

  • Insomnia and depression prior to myocardial infarction.

    abstract::Insomnia is common among patients who subsequently experience an acute myocardial infarction (MI), and is a major symptom of psychiatric depression. The purpose of this study was to determine what proportion of patients reporting insomnia prior to MI have depression. Of 70 patients with a recent MI, 27 (39%) reported ...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章


    authors: Carney RM,Freedland KE,Jaffe AS

    更新日期:1990-11-01 00:00:00

  • Effort-reward imbalance, overcommitment, and measures of cortisol and blood pressure over the working day.

    abstract:OBJECTIVE:To assess the biological correlates of effort-reward imbalance and overcommitment to work using measurements over the working day. METHODS:Participants were 197 working men and women aged 45 to 59 years, recruited from the Whitehall II epidemiological cohort. Salivary cortisol was sampled on waking, 30 minut...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章


    authors: Steptoe A,Siegrist J,Kirschbaum C,Marmot M

    更新日期:2004-05-01 00:00:00

  • Generalized anxiety disorder, major depressive disorder, and their comorbidity as predictors of all-cause and cardiovascular mortality: the Vietnam experience study.

    abstract:OBJECTIVE:To examine whether the 1-year prevalence of major depressive disorder (MDD), generalized anxiety disorder (GAD), and their comorbidity were associated with subsequent all-cause and cardiovascular disease (CVD) mortality during 15 years in Vietnam veterans. METHODS:Participants (N = 4256) were from the Vietna...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章


    authors: Phillips AC,Batty GD,Gale CR,Deary IJ,Osborn D,MacIntyre K,Carroll D

    更新日期:2009-05-01 00:00:00