Early hits and long-term consequences: tracking the lasting impact of prenatal smoke exposure on telomere length in children.

Abstract:

:We examined the association between telomere length and prenatal tobacco exposure (PTE) in 104 children aged 4 to 14 years. Salivary telomere length (STL) was determined from salivary DNA using quantitative polymerase chain reaction. Of the children, 18% had maternal reported PTE. Mean STL was significantly lower among children with PTE (6.4 vs 7.5, P < .05). Findings extend the literature demonstrating the negative long-term effects of PTE to include a cellular marker of aging linked to multiple negative health outcomes.

journal_name

Am J Public Health

authors

Theall KP,McKasson S,Mabile E,Dunaway LF,Drury SS

doi

10.2105/AJPH.2012.301208

subject

Has Abstract

pub_date

2013-10-01 00:00:00

pages

S133-5

eissn

0090-0036

issn

1541-0048

journal_volume

103 Suppl 1

pub_type

杂志文章
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