Abstract:
OBJECTIVES:We postulated the existence of a statin-iron nexus by which statins improve cardiovascular disease outcomes at least partially by countering proinflammatory effects of excess iron stores. METHODS:Using data from a clinical trial of iron (ferritin) reduction in advanced peripheral arterial disease, the Iron and Atherosclerosis Study, we compared effects of ferritin levels versus high-density lipoprotein to low-density lipoprotein ratios (both were randomization variables) on clinical outcomes in participants receiving and not receiving statins. RESULTS:Statins increased high-density lipoprotein to low-density lipoprotein ratios and reduced ferritin levels by noninteracting mechanisms. Improved clinical outcomes were associated with lower ferritin levels but not with improved lipid status. CONCLUSIONS:There are commonalities between the clinical benefits of statins and the maintenance of physiologic iron levels. Iron reduction may be a safe and low-cost alternative to statins.
journal_name
Am J Public Healthjournal_title
American journal of public healthauthors
Zacharski LR,DePalma RG,Shamayeva G,Chow BKdoi
10.2105/AJPH.2012.301163subject
Has Abstractpub_date
2013-04-01 00:00:00pages
e105-12issue
4eissn
0090-0036issn
1541-0048journal_volume
103pub_type
杂志文章,随机对照试验abstract:OBJECTIVES:We tested a structural model of relations among self-reported childhood maltreatment, alcohol and other drug abuse and dependence symptoms, and sexual risk behavior in a sample of adolescents receiving outpatient treatment of substance use problems. METHODS:Structured interviews were administered to an ethn...
journal_title:American journal of public health
pub_type: 杂志文章
doi:10.2105/AJPH.2011.300628
更新日期:2012-05-01 00:00:00
abstract::Data derived through log recordings of 89 nurse practitioners (NPs) in adult/family practice on 7,086 prescriptions issued during 890 clinical days were analyzed to describe prescribing practices of NPs who held prescriptive authority from the licensing regulatory boards of five western states. Results showed drug uti...
journal_title:American journal of public health
pub_type: 杂志文章
doi:10.2105/ajph.75.3.258
更新日期:1985-03-01 00:00:00
abstract::Just before and 4 months after initiation of a condom giveaway program, a questionnaire regarding sexual behavior and condom acquisition was administered to 103 men attending an outpatient drug abuse treatment clinic. Jars filled with a variety of condoms were placed in every clinic room. Condom taking varied as a fun...
journal_title:American journal of public health
pub_type: 杂志文章
doi:10.2105/ajph.82.11.1536
更新日期:1992-11-01 00:00:00
abstract:OBJECTIVES:We examined the relationship between intimate partner violence victimization among women in the general population and emergency department use. We sought to discern whether race/ethnicity moderates this relationship and to explore these relationships in race/ethnic-specific models. METHODS:We used data on ...
journal_title:American journal of public health
pub_type: 杂志文章
doi:10.2105/AJPH.2006.091116
更新日期:2007-12-01 00:00:00
abstract::Data were employed from confirmed measles case reports and an immunization survey to estimate the apparent effectiveness of measles vaccine in Los Angeles County in 1976. We evaluated the age-specific proportions of our case load arising from persons erroneously thought to possess immunity. Thirty five per cent of our...
journal_title:American journal of public health
pub_type: 杂志文章
doi:10.2105/ajph.69.10.1055
更新日期:1979-10-01 00:00:00
abstract::Objectives. To document the collective effort of diaper banks in the United States and to estimate the percentage of low-income children whose diaper need is met through these efforts.Methods. For each state, we compared the number of children younger than 4 years in families living at or below 200% of the federal pov...
journal_title:American journal of public health
pub_type: 杂志文章
doi:10.2105/AJPH.2019.305377
更新日期:2020-01-01 00:00:00
abstract::Vital statistics show that a rise in incidence of endometrial cancer began in the mid-1960s on the West Coast of the United States. This rise was continuous and reached a peak in 1975. Elsewhere, incidence rates for endometrial cancer rose during the 1970s. It now seems evident that much of the rise in all areas of th...
journal_title:American journal of public health
pub_type: 杂志文章
doi:10.2105/ajph.70.3.264
更新日期:1980-03-01 00:00:00
abstract::Members of the Reorganized Church of Jesus Christ of Latter-Day Saints (RLDS) are dissuaded from the use of tobacco, alcohol, and hot drinks. A well-balanced diet is also stressed. This study compares the 1972-78 mortality experience of the Missouri RLDS with three other population groups. The findings show Missouri R...
journal_title:American journal of public health
pub_type: 杂志文章
doi:10.2105/ajph.71.12.1350
更新日期:1981-12-01 00:00:00
abstract:OBJECTIVES:We estimated the prevalence and incidence of gender identity disorder (GID) diagnoses among veterans in the Veterans Health Administration (VHA) health care system and examined suicide risk among veterans with a GID diagnosis. METHODS:We examined VHA electronic medical records from 2000 through 2011 for 2 o...
journal_title:American journal of public health
pub_type: 杂志文章
doi:10.2105/AJPH.2013.301507
更新日期:2013-10-01 00:00:00
abstract:OBJECTIVES:The Minnesota Heart Health Program is a 13-year research and demonstration project to reduce morbidity and mortality from coronary heart disease in whole communities. METHODS:Three pairs of communities were matched on size and type; each pair had one education site and one comparison site. After baseline su...
journal_title:American journal of public health
pub_type: 杂志文章
doi:10.2105/ajph.84.9.1383
更新日期:1994-09-01 00:00:00
abstract:OBJECTIVES:Our study tested the effectiveness of network methods for identifying opinion leaders and for constructing groups. METHODS:Three conditions-random, teacher, and network--ere randomly assigned to 84 6th-grade classrooms within 16 schools. Pre- and postcurriculum data on mediators of tobacco use were collecte...
journal_title:American journal of public health
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.2105/ajph.93.11.1837
更新日期:2003-11-01 00:00:00
abstract:OBJECTIVES:To investigate racial/ethnic and gender inequities in the compensation and benefits of US health care workers and assess the potential impact of a $15-per-hour minimum wage on their economic well-being. METHODS:Using the 2017 Annual Social and Economic Supplement to the Current Population Survey, we compare...
journal_title:American journal of public health
pub_type: 杂志文章
doi:10.2105/AJPH.2018.304801
更新日期:2019-02-01 00:00:00
abstract:OBJECTIVES:Data from the Tecumseh Community Health Study were used to estimate excess morbidity owing to influenza, and results were compared with estimates made previously using different methodology for an Institute of Medicine report. METHODS:Study participants from Tecumseh, Michigan, were classified as infected o...
journal_title:American journal of public health
pub_type: 杂志文章
doi:10.2105/ajph.83.12.1712
更新日期:1993-12-01 00:00:00
abstract:OBJECTIVES:We examined the relationship between quality improvement (QI) maturity and accreditation attributes of US local health departments (LHDs), specifically those in Nebraska. METHODS:Using 2011 Nebraska LHD QI survey data, we conducted Spearman correlation analyses between QI maturity domains and accreditation ...
journal_title:American journal of public health
pub_type: 杂志文章
doi:10.2105/AJPH.2014.302278
更新日期:2015-04-01 00:00:00
abstract:OBJECTIVES:An association of smoking with depression and anxiety has been documented in adult smokers. This study examines this association in a representative group of teenage smokers. METHODS:A two-stage cluster sample of secondary school students in Victoria, Australia, were surveyed by using a computerized questio...
journal_title:American journal of public health
pub_type: 杂志文章
doi:10.2105/ajph.86.2.225
更新日期:1996-02-01 00:00:00
abstract:OBJECTIVES:To determine the association between multiple drug use and nonfatal overdose among young people (younger than 30 years) who inject drugs. METHODS:We completed a longitudinal study of 173 injection drug users younger than 30 years living in San Francisco, California, between April 2012 and February 2014. RE...
journal_title:American journal of public health
pub_type: 杂志文章
doi:10.2105/AJPH.2016.303084
更新日期:2016-05-01 00:00:00
abstract::Iodine-131 was found to dominate the gamma spectra of dried sludge and concentration liquid effluent samples from a sewage treatment plant serving the area containing the Texas Medical Center in 1975. The concentration of Iodine-131 varied considerably on a time scale of weeks but was fairly stable in the course of a ...
journal_title:American journal of public health
pub_type: 杂志文章
doi:10.2105/ajph.71.1.47
更新日期:1981-01-01 00:00:00
abstract::A questionnaire survey of the 127 US medical schools was undertaken to assess the present status of occupational health teaching as a follow-up to two prior similar studies. The present study revealed that 78 (68%) of the 115 responding schools specifically taught occupational health during the 1991/92 academic year, ...
journal_title:American journal of public health
pub_type: 杂志文章
doi:10.2105/ajph.84.5.846
更新日期:1994-05-01 00:00:00
abstract:OBJECTIVES:We compared childbirth-related outcomes for Medicaid recipients who received prenatal education and childbirth support from trained doulas with outcomes from a national sample of similar women and estimated potential cost savings. METHODS:We calculated descriptive statistics for Medicaid-funded births natio...
journal_title:American journal of public health
pub_type: 杂志文章
doi:10.2105/AJPH.2012.301201
更新日期:2013-04-01 00:00:00
abstract::Of the 47 states that participated in a 1983 survey of State Health Departments, 30 were found to have public health standards in place or started. Most states' standards emphasize the range of services to be provided, but substantial variations were found in how standards are formulated, adopted, and used by state an...
journal_title:American journal of public health
pub_type: 杂志文章
doi:10.2105/ajph.75.6.649
更新日期:1985-06-01 00:00:00
abstract:OBJECTIVES:The purpose of this study was to identify behaviors associated with change in body mass index or with weight gain at the waist. METHODS:A cohort of 79236 White, non-Hispanic, healthy adults was questioned in 1982 and 1992 about diet and 10 physical activities. Estimates were made of the mean effects of stab...
journal_title:American journal of public health
pub_type: 杂志文章
doi:10.2105/ajph.87.5.747
更新日期:1997-05-01 00:00:00
abstract:OBJECTIVES:We estimated the costs associated with reducing class sizes in kindergarten through grade 3 as well as the effects of small class sizes on selected outcomes such as quality-adjusted life-years and future earnings. METHODS:We used multiple data sets to predict changes in the outcomes assessed according to le...
journal_title:American journal of public health
pub_type: 杂志文章
doi:10.2105/AJPH.2006.105478
更新日期:2007-11-01 00:00:00
abstract:OBJECTIVES:To test the effectiveness of a preclinical, telephone-based patient navigation intervention to encourage colorectal cancer (CRC) screening among older Black men. METHODS:We conducted a 3-parallel-arm, randomized trial among 731 self-identified Black men recruited at barbershops between 2010 and 2013 in New ...
journal_title:American journal of public health
pub_type: 杂志文章,随机对照试验
doi:10.2105/AJPH.2017.303885
更新日期:2017-09-01 00:00:00
abstract:OBJECTIVES:We determined differences in weight at age 18 years and at current age and weight change by sexual orientation within different racial/ethnic populations, stratifying by gender. METHODS:We used 2001-2007 data from the California Health Interview Survey, resulting in an unweighted sample of 120,274 individua...
journal_title:American journal of public health
pub_type: 杂志文章
doi:10.2105/AJPH.2013.301391
更新日期:2014-01-01 00:00:00
abstract:OBJECTIVES:We sought to determine the amount of time required for a primary care physician to provide recommended preventive services to an average patient panel. METHODS:We used published and estimated times per service to determine the physician time required to provide all services recommended by the US Preventive ...
journal_title:American journal of public health
pub_type: 杂志文章
doi:10.2105/ajph.93.4.635
更新日期:2003-04-01 00:00:00
abstract::In an effort to keep abreast of the changing needs of a more affluent society and to ensure better value for money, the British are reforming their National Health Service. They are promoting competition and entrepreneurship, and directing funding to follow a patient rather than flowing directly to institutions. Briti...
journal_title:American journal of public health
pub_type: 杂志文章
doi:10.2105/ajph.81.12.1566
更新日期:1991-12-01 00:00:00
abstract:OBJECTIVES:The purpose of this study was to describe differences in childhood pesticide exposures between counties on the Texas-Mexico border and nonborder counties. METHOD:The authors reviewed all pesticide exposures among children younger than 6 years reported to the South Texas Poison Center during 1997 through 200...
journal_title:American journal of public health
pub_type: 杂志文章
doi:10.2105/ajph.93.8.1310
更新日期:2003-08-01 00:00:00
abstract:OBJECTIVES:We evaluated the effectiveness of the Public Health Detailing Program in helping primary care providers and their staff to improve patient care on public health challenges. METHODS:We analyzed reported changes in clinical practice or behavior by examining providers' retention and implementation of recommend...
journal_title:American journal of public health
pub_type: 杂志文章
doi:10.2105/AJPH.2011.300622
更新日期:2012-06-01 00:00:00
abstract:OBJECTIVES:We evaluated the effect of a weight gain prevention intervention (Shape Program) on depression among socioeconomically disadvantaged overweight and obese Black women. METHODS:Between 2009 and 2012, we conducted a randomized trial comparing a 12-month electronic health-based weight gain prevention interventi...
journal_title:American journal of public health
pub_type: 杂志文章,随机对照试验
doi:10.2105/AJPH.2014.302004
更新日期:2014-09-01 00:00:00
abstract:OBJECTIVES:This study sought to define, among sexually transmitted disease (STD) clinic attendees, (1) patterns of sex partner selection, (2) relative risks for gonococcal or chlamydial infection associated with each mixing pattern, and (3) selected links and potential and actual bridge populations. METHODS:Mixing mat...
journal_title:American journal of public health
pub_type: 杂志文章
doi:10.2105/ajph.89.6.825
更新日期:1999-06-01 00:00:00