Detrimental effects of four hours of cold storage on porcine pancreaticoduodenal transplantation.

Abstract:

:Transplantation of the pancreaticoduodenal allograft (PDA) has recently been advocated as a technique that is superior to the use of the segmental allograft. However, the effect of simple cold storage preservation on the PDA has not been studied. We investigated the effect of 24 and 4 hours of cold storage in Eurocollins solution on porcine PDA function after transplantation in pancreatectomized pigs. A regimen of cyclosporine and prednisone was used, which prevented rejection for at least 28 days after transplantation. Cold storage preservation for 24 hours uniformly resulted in PDA failure. Compared with recipients of immediately transplanted PDA, recipients of PDA cold stored for 4 hours had marked plasma hyperamylasemia (10,000 U/L versus 1932 U/L), relative glucose intolerance (K value -2.15 versus -2.66), hypoinsulinemia (peak immunoreactive insulin 11.0 microU/ml versus 34.7 microU/ml), and an abnormal pattern of insulin secretion as demonstrated with intravenous glucose tolerance testing. There was also a higher incidence of technical complications in the group transplanted with cold-stored PDAs. Our results suggest that there is a detrimental effect on porcine PDA function after only 4 hours of cold storage in Eurocollins solution.

journal_name

Surgery

journal_title

Surgery

authors

Dafoe DC,Campbell DA Jr,Marks WH,Borgstrom A,Merion RM,Berlin RE,Turcotte JG

subject

Has Abstract

pub_date

1986-02-01 00:00:00

pages

170-7

issue

2

eissn

0039-6060

issn

1532-7361

pii

0039-6060(86)90181-9

journal_volume

99

pub_type

杂志文章

相关文献

SURGERY文献大全
  • Total gastrectomy in patients with gastric adenocarcinoma: Is there an advantage to the minimally invasive approach?

    abstract:BACKGROUND:Previous evaluations of the oncologic efficacy of minimally invasive approaches to total gastrectomy in gastric adenocarcinoma have been limited by sample size and duration of follow-up. METHODS:We queried the National Cancer Database to identify patients undergoing robotic and laparoscopic or open total ga...

    journal_title:Surgery

    pub_type: 杂志文章

    doi:10.1016/j.surg.2019.05.041

    authors: Sweigert PJ,Eguia E,Nelson MH,Nassoiy SP,Knab LM,Abood G,Baker MS

    更新日期:2019-10-01 00:00:00

  • Kinetic analysis of the rapid intraoperative parathyroid hormone assay in patients during operation for hyperparathyroidism.

    abstract:BACKGROUND:Rapid intraoperative parathyroid hormone (RI-PTH) assay is used to guide adequacy of resection during operation for hyperparathyroidism. We compared the RI-PTH assay (15 minutes) with a standard PTH assay, determined whether the PTH half-life varied between patients, and constructed a kinetic analysis of the...

    journal_title:Surgery

    pub_type: 杂志文章

    doi:10.1067/msy.2099.101835

    authors: Libutti SK,Alexander HR,Bartlett DL,Sampson ML,Ruddel ME,Skarulis M,Marx SJ,Spiegel AM,Simmonds W,Remaley AT

    更新日期:1999-12-01 00:00:00

  • The mechanisms of angiogenesis in hepatocellular carcinoma: angiogenic switch during tumor progression.

    abstract::Solid tumors constantly require a vascular supply for their progression and metastasis. Hepatocellular carcinoma (HCC) is known to gain its hypervascularity during the process of dedifferentiation and progression. Various angiogenic growth factors and inhibitors regulate this angiogenic switch of HCC. The known endoth...

    journal_title:Surgery

    pub_type: 杂志文章,评审

    doi:10.1067/msy.2002.119365

    authors: Sugimachi K,Tanaka S,Terashi T,Taguchi K,Rikimaru T,Sugimachi K

    更新日期:2002-01-01 00:00:00

  • Does vagal nerve stimulation affect body composition and metabolism? Experimental study of a new potential technique in bariatric surgery.

    abstract:BACKGROUND:It has been shown that vagal nerve stimulation (VNS) can affect body mass. The aim of this study was to evaluate effect of VNS on body mass, body composition, metabolic rate, and plasma leptin and IGF-I levels. METHODS:Eight female pigs were included in the study. Under general anesthesia, a bipolar electro...

    journal_title:Surgery

    pub_type: 杂志文章

    doi:10.1016/j.surg.2005.06.025

    authors: Sobocki J,Fourtanier G,Estany J,Otal P

    更新日期:2006-02-01 00:00:00

  • Reducing postoperative pain, narcotics, and length of hospitalization.

    abstract::Bupivacaine wound infiltration together with efficient esophagogastric decompression and immediate elemental feeding in 43 consecutive, well-instructed patients who had undergone cholecystectomy reduced their postoperative analgesia requirements to an average of 17 (+/- 46, SD) mg of meperidine during the initial 24 h...

    journal_title:Surgery

    pub_type: 杂志文章

    doi:

    authors: Moss G,Regal ME,Lichtig L

    更新日期:1986-02-01 00:00:00

  • Cytokine induction of interferon regulatory factor-1 in hepatocytes.

    abstract:BACKGROUND:Interferon regulatory factor-1 (IRF-1) is a transcriptional factor originally cloned from fibroblasts that activates interferons and certain interferon-responsive genes. Because IRF-1 is an "early-immediate" nuclear protein, it can function acutely after trauma or septic stimuli. We have identified IRF-1 exp...

    journal_title:Surgery

    pub_type: 杂志文章

    doi:

    authors: Geller DA,Nguyen D,Shapiro RA,Nussler A,Di Silvio M,Freeswick P,Wang SC,Tweardy DJ,Simmons RL,Billiar TR

    更新日期:1993-08-01 00:00:00

  • Impact of obesity on surgical outcomes of laparoscopic distal pancreatectomy: A Norwegian single-center study.

    abstract:BACKGROUND:Obesity is known as a risk factor for intra- and postoperative complications in pancreatic operation. However, the operative outcomes in obese patients undergoing laparoscopic distal pancreatectomy remain unclear. METHODS:A total number of 423 patients underwent laparoscopic distal pancreatectomy at Oslo Un...

    journal_title:Surgery

    pub_type: 杂志文章

    doi:10.1016/j.surg.2016.05.046

    authors: Sahakyan MA,Røsok BI,Kazaryan AM,Barkhatov L,Lai X,Kleive D,Ignjatovic D,Labori KJ,Edwin B

    更新日期:2016-11-01 00:00:00

  • Reduced apoprotein B and increased lipoprotein turnover in cholesterol-fed rabbits after partial ileal bypass.

    abstract::Plasma lipid and lipoprotein levels and composition of the very low-, low-, and high-density lipoproteins (VLDL, LDL, HDL) were studied in white New Zealand rabbits in the control state, 8 weeks after initiation of a 2% cholesterol-enriched diet, and sequentially for 16 weeks following a partial ileal bypass (PIB) pro...

    journal_title:Surgery

    pub_type: 杂志文章

    doi:

    authors: Sirtori CR,Ghiselli GC,Catapano AL,Lovati MR,Fragiacomo C,Fox U,Majone G,Buchwald H

    更新日期:1981-02-01 00:00:00

  • Hospital markup and operation outcomes in the United States.

    abstract:BACKGROUND:Although the price hospitals charge for operations has broad financial implications, hospital pricing is not subject to regulation. We sought to characterize national variation in hospital price markup for major cardiothoracic and gastrointestinal operations and to evaluate perioperative outcomes of hospital...

    journal_title:Surgery

    pub_type: 杂志文章

    doi:10.1016/j.surg.2016.03.014

    authors: Gani F,Ejaz A,Makary MA,Pawlik TM

    更新日期:2016-07-01 00:00:00

  • Cyclosporine suppression of lymphocyte recruitment, regional blood flow, and vascular permeability at sites of allogeneic cellular interactions.

    abstract::Although cyclosporine (CsA) has been thought to act primarily on the afferent phase of the immune response, we can demonstrate that it also acts at the efferent phase. The effect of CsA on lymphocyte recruitment (LR), regional blood flow (RBF), and vascular permeability (VP) was studied in paired, healed, subcutaneous...

    journal_title:Surgery

    pub_type: 杂志文章

    doi:

    authors: Hanto DW,Harty JT,Hoffman R,Simmons RL

    更新日期:1983-08-01 00:00:00

  • beta2 Adrenoreceptor blockade attenuates the hyperinflammatory response induced by traumatic injury.

    abstract:BACKGROUND:Major operative injury initiates immunologic changes that may result in a systemic inflammatory response, leading to organ dysfunction/sepsis. Catecholamines seem to be key mediators. The effects of beta(2) receptor blockade in vitro and in vivo before and after operative injury were studied to clarify their...

    journal_title:Surgery

    pub_type: 杂志文章

    doi:10.1016/j.surg.2008.09.013

    authors: Rough J,Engdahl R,Opperman K,Yerrum S,Monroy MA,Daly JM

    更新日期:2009-02-01 00:00:00

  • The efficacy of simultaneous fine-needle aspiration and large-needle biopsy of the thyroid gland.

    abstract::Fine-needle aspirations and cutting needle biopsies were performed on 415 patients with solitary thyroid nodules. All nodules were considered hypofunctioning by scintiscans. Specimens were adequate in 399 patients. Ten percent of these patients had thyroid cancers documented by thyroidectomies. Results from either or ...

    journal_title:Surgery

    pub_type: 杂志文章

    doi:

    authors: Nishiyama RH,Bigos ST,Goldfarb WB,Flynn SD,Taxiarchis LN

    更新日期:1986-12-01 00:00:00

  • Resection of abdominal aortic aneurysm in the presence of horseshoe kidney.

    abstract::We report four cases of abdominal aortic aneurysm associated with horseshoe kidney. These cases illustrate the factors that determine the ease of resection in this situation: whether the isthmus of the kidney is parenchymatous or thin and fibrous; the presence or absence of anomalous renal arteries; and the origin of ...

    journal_title:Surgery

    pub_type: 杂志文章

    doi:

    authors: Starr DS,Foster WJ,Morris GC Jr

    更新日期:1981-03-01 00:00:00

  • Screening for primary hyperparathyroidism before thyroid surgery: A prospective study.

    abstract:BACKGROUND:Misdiagnosed primary hyperparathyroidism (PHPT) during thyroid surgery may lead to a difficult reoperation. Because PHPT is often asymptomatic, calcium measurements have been recommended before thyroid surgery, but no study has focused on the results of a prospective PHPT screening. METHODS:The prospective ...

    journal_title:Surgery

    pub_type: 杂志文章

    doi:10.1067/msy.2002.121379

    authors: Denizot A,Dadoun F,Meyer-Dutour A,Alliot P,Argème M

    更新日期:2002-03-01 00:00:00

  • Progression and survival results after radical hepatic metastasectomy of indolent advanced neuroendocrine neoplasms (NENs) supports an aggressive surgical approach.

    abstract:BACKGROUND:Neuroendocrine neoplasms most commonly metastasize to the liver. Operative extirpation of neuroendocrine neoplasm hepatic metastases improves symptoms and seems to improve survival, but subsequent evidence is required. The current study evaluates the progression-free survival and overall survival of patients...

    journal_title:Surgery

    pub_type: 杂志文章

    doi:10.1016/j.surg.2010.06.008

    authors: Saxena A,Chua TC,Sarkar A,Chu F,Liauw W,Zhao J,Morris DL

    更新日期:2011-02-01 00:00:00

  • Preoperative enteral access is not necessary prior to multimodality treatment of esophageal cancer.

    abstract:BACKGROUND:Surgical enteral access prior to multimodality treatment for esophageal cancer is controversial as dysphagia is often used for feeding tube referral. We hypothesized that enteral access before neoadjuvant chemoradiation for esophageal cancer provides no benefit compared to that placed during definitive esoph...

    journal_title:Surgery

    pub_type: 杂志文章

    doi:10.1016/j.surg.2017.09.046

    authors: Jenkins TK,Lopez AN,Sarosi GA,Ben-David K,Thomas RM

    更新日期:2018-04-01 00:00:00

  • Central lymph node dissection as a secondary procedure for papillary thyroid cancer: Is there added morbidity?

    abstract:BACKGROUND:Routine central lymph node dissection (CLND) for papillary thyroid cancer (PTC) at the time of initial thyroidectomy has been advocated with a demonstrated decrease in post-ablation serum thyroglobulin compared to total thyroidectomy alone. Patients now present with central compartment metastatic disease aft...

    journal_title:Surgery

    pub_type: 杂志文章

    doi:10.1016/j.surg.2009.01.013

    authors: Alvarado R,Sywak MS,Delbridge L,Sidhu SB

    更新日期:2009-05-01 00:00:00

  • Computer vision in surgery.

    abstract::The fields of computer vision (CV) and artificial intelligence (AI) have undergone rapid advancements in the past decade, many of which have been applied to the analysis of intraoperative video. These advances are driven by wide-spread application of deep learning, which leverages multiple layers of neural networks to...

    journal_title:Surgery

    pub_type: 杂志文章

    doi:10.1016/j.surg.2020.10.039

    authors: Ward TM,Mascagni P,Ban Y,Rosman G,Padoy N,Meireles O,Hashimoto DA

    更新日期:2020-11-30 00:00:00

  • In vitro studies of parathyroid hormone release: effect of cimetidine.

    abstract::We studied parathyroid hormone (PTH) release from cell suspensions of fresh and cryopreserved human parathyroid tissue. A sensitive PTH assay with midregion specificity and adaptation of "micro" methods of cell plating permitted conservation of tissue (200 microliters aliquots) and high reproducibility (5 to 10 aliquo...

    journal_title:Surgery

    pub_type: 杂志文章

    doi:

    authors: Saxe AW,Chen SL,Marx SJ,Brennan MF

    更新日期:1982-11-01 00:00:00

  • Changes in the levels of endogenous antioxidants in the liver of mice with experimental endotoxemia and the protective effects of the antioxidants.

    abstract::Gram-negative bacterial endotoxin (lipopolysaccharide) induces hepatic damage in mice caused by lipid peroxidation, and administration of antioxidants (coenzyme Q10 and alpha-tocopherol) suppresses this lipid peroxidation, preserves energy metabolism, and enhances the survival of endotoxin-administered mice. Therefore...

    journal_title:Surgery

    pub_type: 杂志文章

    doi:

    authors: Sugino K,Dohi K,Yamada K,Kawasaki T

    更新日期:1989-02-01 00:00:00

  • Extrinsic intestinal reinnervation after canine small bowel autotransplantation.

    abstract:BACKGROUND:The process of extrinsic reinnervation after small bowel transplantation is poorly understood. METHODS:Jejunal and ileal specimens, obtained from the dogs that underwent intestinal autotransplantation by an end-to end (E-E) or end-to-side arterial reconstruction, were analyzed at 1 (n = 7), 3 (n = 6), 6 (n ...

    journal_title:Surgery

    pub_type: 杂志文章

    doi:

    authors: Sugitani A,Reynolds JC,Tsuboi M,Todo S

    更新日期:1998-01-01 00:00:00

  • Thyroglobulin washout from cervical lymph node fine needle aspiration biopsies in patients with differentiated thyroid cancer: an analysis of different expressions to use in post-total thyroidectomy follow-up.

    abstract:INTRODUCTION:Although frequently used as an adjunct to cytology in patients with differentiated thyroid cancers, interpretation of thyroglobulin washout remains unclear. We aim to compare the utility of different analytic tools to develop recommendations for use in post-total thyroidectomy follow-up. METHODS:This is a...

    journal_title:Surgery

    pub_type: 杂志文章

    doi:10.1016/j.surg.2019.05.083

    authors: Kahramangil B,Kose E,Donmez M,Aydin H,Reynolds JP,Krishnamurthy V,Jin J,Shin J,Siperstein A,Berber E

    更新日期:2020-01-01 00:00:00

  • Thyroglossal duct carcinoma.

    abstract::Thyroglossal cysts are common developmental abnormalities of the thyroid gland. The malignant form of these cysts, however, is extremely rare, with fewer than 100 cases reported since 1915. Here we add 10 cases of malignant thyroglossal cysts, nine women and one man, encountered at M.D. Anderson Cancer Center, based o...

    journal_title:Surgery

    pub_type: 杂志文章

    doi:

    authors: Fernandez JF,Ordoñez NG,Schultz PN,Samaan NA,Hickey RC

    更新日期:1991-12-01 00:00:00

  • Preoperative immunonutrition decreases postoperative complications by modulating prostaglandin E2 production and T-cell differentiation in patients undergoing pancreatoduodenectomy.

    abstract:BACKGROUND:An immune-enhancing diet has been used to alter eicosanoid synthesis, cytokine production, and immune function in an attempt to limit the undesired immune reactions after injury from surgery. This prospective randomized study was designed to investigate the effect of preoperative immunonutrition on operative...

    journal_title:Surgery

    pub_type: 杂志文章,随机对照试验

    doi:10.1016/j.surg.2013.05.040

    authors: Aida T,Furukawa K,Suzuki D,Shimizu H,Yoshidome H,Ohtsuka M,Kato A,Yoshitomi H,Miyazaki M

    更新日期:2014-01-01 00:00:00

  • Nitric oxide regulates insulin secretion in the isolated perfused human pancreas via a cholinergic mechanism.

    abstract:BACKGROUND:The purpose of this study was to determine whether nitric oxide regulates insulin secretion in the isolated perfused human pancreas. METHODS:Single-pass perfusion was performed in four pancreata with a modified Krebs medium. Sequential 10-minute infusions (separated by 10-minute basal periods) of (1) 25 nmo...

    journal_title:Surgery

    pub_type: 杂志文章

    doi:10.1016/s0039-6060(96)80305-9

    authors: Atiya A,Cohen G,Ignarro L,Brunicardi FC

    更新日期:1996-08-01 00:00:00

  • Duodenum-preserving pancreatic head resection: A retrospective analysis of the Hamburg Modification.

    abstract:BACKGROUND:Chronic pancreatitis remains a challenging inflammatory disease, causing progressive, irreversible fibrosis of the pancreatic parenchyma. Several surgical options for treatment have been established, but duodenum-preserving pancreatic head resections seem to be the most favorable option other than pancreatod...

    journal_title:Surgery

    pub_type: 杂志文章

    doi:10.1016/j.surg.2018.11.009

    authors: Bellon E,Roswora MD,Melling N,Grotelueschen R,Grupp K,Reeh M,Ghadban T,Izbicki JR,Bachmann K

    更新日期:2019-05-01 00:00:00

  • Roux-en-Y gastric bypass improves glucose homeostasis, reduces oxidative stress and inflammation in livers of obese rats and in Kupffer cells via an AMPK-dependent pathway.

    abstract:BACKGROUND:Oxidative stress and inflammation are implicated in the pathogenesis of steatohepatitis. We hypothesize that Roux-en-Y gastric bypass reduces oxidative stress and inflammation in the liver of obese rats via activation of AMPK-α. METHODS:Obese Sprague-Dawley male rats underwent either sham operation or Roux-...

    journal_title:Surgery

    pub_type: 杂志文章

    doi:10.1016/j.surg.2017.01.012

    authors: Peng Y,Li JZ,You M,Murr MM

    更新日期:2017-07-01 00:00:00

  • Deep learning-based computer vision to recognize and classify suturing gestures in robot-assisted surgery.

    abstract:BACKGROUND:Our previous work classified a taxonomy of suturing gestures during a vesicourethral anastomosis of robotic radical prostatectomy in association with tissue tears and patient outcomes. Herein, we train deep learning-based computer vision to automate the identification and classification of suturing gestures ...

    journal_title:Surgery

    pub_type: 杂志文章

    doi:10.1016/j.surg.2020.08.016

    authors: Luongo F,Hakim R,Nguyen JH,Anandkumar A,Hung AJ

    更新日期:2020-09-26 00:00:00

  • Reduction of transfusion requirements during major hepatic resection for metastatic disease.

    abstract:BACKGROUND:Our purpose was to determine whether the combination of total liver vascular inflow occlusion (Pringle maneuver) and rapid hepatic transection with a clamp-crush technique results in significant reduction of blood loss and transfusion requirements during major hepatic resections. METHODS:A series of 49 adul...

    journal_title:Surgery

    pub_type: 杂志文章

    doi:

    authors: Arnoletti JP,Brodsky J

    更新日期:1999-02-01 00:00:00

  • The vascular steal phenomenon: an experimental model.

    abstract::A model for the vascular steal phenomenon was designed and evaluated in 10 mongrel dogs in which the aortic bifurcation was used to represent a parent artery with two distal vascular beds. Right lower extremity flow was increased with a femoral arteriovenous fistula, and progressively greater stenoses were applied to ...

    journal_title:Surgery

    pub_type: 杂志文章

    doi:

    authors: Billet A,Queral LA,Polito WF,Dagher FJ

    更新日期:1984-11-01 00:00:00