Abstract:
:Soluble membrane fractions derived from polyoma tumor cells trigger lymphocytes, derived from polyoma-immunized animals, but not from nonimmunized controls, to release the lymphokine, macrophage migration-inhibitory factor. The reaction can be blocked by sera from polyoma-bearing animals. Absorption of these sera with polyoma cells, but not with nonpolyoma cell lines, abrogates this activity. These findings suggest that there is a polyoma virus-induced membrane component that can induce polyoma-specific macrophage migration inhibition.
journal_name
Cancer Resjournal_title
Cancer researchauthors
Ramqvist T,Dalianis T,Reinholdsson G,Klein G,Szigeti Rsubject
Has Abstractpub_date
1986-10-01 00:00:00pages
5045-8issue
10eissn
0008-5472issn
1538-7445journal_volume
46pub_type
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