Abstract:
:In a previous study, deviance in the reaction time (RT) distribution of saccades for patients with schizophrenia was explained using an oculomotor decision model. Here, RTs of visually guided saccades in young healthy men, healthy children, older adults, patients with schizophrenia, and patients with obsessive compulsive disorder (OCD) were modeled to study the specificity of this decision process deviance for schizophrenia. The mean decision rate to saccade decreased with age in children and increased in older adults while the decision rate intrasubject variability (ISV) was not modulated by age. A significant increase in ISV of the decision rate was confirmed for patients with schizophrenia but not OCD compared to healthy controls. There was no effect of medication on model parameters in the OCD patient group. These results confirm the specificity of the deviance in a simple oculomotor decision process in schizophrenia.
journal_name
Psychophysiologyjournal_title
Psychophysiologyauthors
Theleritis C,Evdokimidis I,Smyrnis Ndoi
10.1111/psyp.12178subject
Has Abstractpub_date
2014-04-01 00:00:00pages
327-36issue
4eissn
0048-5772issn
1540-5958journal_volume
51pub_type
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