Abstract:
:High and low reactors were preselected on the basis of their heart rate reactivity to a speech stressor in a prescreening session. In the main study, subjects were exposed to a mental arithmetic plus noise stressor. Cardiovascular activity was recorded during baseline and stressor, and blood was drawn prior to and following the stressor for endocrine and immune assays. Results revealed that the stressor decreased the blastogenic response to concanavalin A and increased natural killer cell numbers and cytotoxicity, absolute numbers of CD8+ T-lymphocytes, norepinephrine and epinephrine levels, heart rate, and blood pressure responses. In addition, cortisol and natural killer cell cytotoxicity responses to the stressor differentiated individuals high versus low in heart rate reactivity. These results suggest that the interactions among the autonomic nervous system, endocrine system, and immune system are not only amenable to psychophysiological analysis but that such analyses may play an important role in illuminating underlying mechanisms.
journal_name
Psychophysiologyjournal_title
Psychophysiologyauthors
Sgoutas-Emch SA,Cacioppo JT,Uchino BN,Malarkey W,Pearl D,Kiecolt-Glaser JK,Glaser Rdoi
10.1111/j.1469-8986.1994.tb02215.xsubject
Has Abstractpub_date
1994-05-01 00:00:00pages
264-71issue
3eissn
0048-5772issn
1540-5958journal_volume
31pub_type
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