Abstract:
:Concussion is the most common form of traumatic brain injury (TBI), but diagnosis remains controversial because the brain appears quite normal in conventional computed tomography and magnetic resonance imaging (MRI). These conventional tools are not sensitive enough to detect diffuse traumatic axonal injury, and cannot depict aberrations in mild TBIs. Advanced MRI modalities including diffusion tensor imaging (DTI), and magnetic resonance spectroscopy (MRS), make it possible to detect brain injuries in TBI. The purpose of this review is to provide the latest information regarding the visualization and quantification of important abnormalities in TBI and new insights into their clinical significance. Advanced imaging modalities allow the discovery of biomarkers of injury and the detection of changes in brain injury over time. Such tools will likely be used to evaluate treatment efficacy in research. Combining multiple imaging modalities would not only provide greater insight into the underlying physiological changes in TBI, but also improve diagnostic accuracy in predicting outcomes. In this review we present evidence of brain abnormalities in TBI based on investigations using MRI, including DTI and MRS. Our review provides a summary of some of the important studies published from 2002 to 2012 on the topic of MRI findings in head trauma. With the growing realization that even mild head injury can lead to neurocognitive deficits, medical imaging has assumed preeminence for detecting abnormalities associated with TBI. Advanced MRI modalities such as DTI and MRS have an important role in the diagnosis of lesions for TBI patients.
journal_name
Brain Imaging Behavjournal_title
Brain imaging and behaviorauthors
Xiong KL,Zhu YS,Zhang WGdoi
10.1007/s11682-013-9288-2subject
Has Abstractpub_date
2014-12-01 00:00:00pages
487-96issue
4eissn
1931-7557issn
1931-7565journal_volume
8pub_type
杂志文章,评审abstract::Changes in large-scale brain networks that accompany mild traumatic brain injury (mTBI) were investigated using functional magnetic resonance imaging (fMRI) during the N-back working memory task at two cognitive loads (1-back and 2-back). Thirty mTBI patients were examined during the chronic stage of injury and compar...
journal_title:Brain imaging and behavior
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journal_title:Brain imaging and behavior
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journal_title:Brain imaging and behavior
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doi:10.1007/s11682-015-9483-4
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journal_title:Brain imaging and behavior
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journal_title:Brain imaging and behavior
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更新日期:2011-09-01 00:00:00
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