SecA is required for membrane targeting of the cell division protein DivIVA in vivo.

abstract：:Acetogens can fix carbon (CO or CO2) into acetyl-CoA via the Wood-Ljungdahl pathway (WLP) that also makes them attractive cell factories for the production of fuels and chemicals from waste feedstocks. Although most biochemical details of the WLP are well understood and systems-level characterization of acetogen metab...

journal_title：Frontiers in microbiology

authors： de Souza Pinto Lemgruber R,Valgepea K,Gonzalez Garcia RA,de Bakker C,Palfreyman RW,Tappel R,Köpke M,Simpson SD,Nielsen LK,Marcellin E

更新日期：2019-11-15 00:00:00

abstract：:Parasites are key drivers of phytoplankton bloom dynamics and related aquatic ecosystem processes. Yet, the dearth of morphological and molecular information hinders the assessment of their diversity and ecological role. Using single-cell techniques, we characterise morphologically and molecularly, intracellular paras...

journal_title：Frontiers in microbiology

authors： Garvetto A,Nézan E,Badis Y,Bilien G,Arce P,Bresnan E,Gachon CMM,Siano R

更新日期：2018-12-03 00:00:00

abstract：:Putrescine is widely used in industrial production of bioplastics, pharmaceuticals, agrochemicals, and surfactants. Although engineered Corynebacterium glutamicum has been successfully used to produce high levels of putrescine, the overall cellular physiological and metabolic changes caused by overproduction of putres...

journal_title：Frontiers in microbiology

authors： Li Z,Liu JZ

更新日期：2017-10-17 00:00:00

abstract：:Studies using a fungal model, Saccharomyces cerevisiae, have been instrumental in advancing our understanding of sulfur metabolism in eukaryotes. Sulfur metabolites, particularly methionine and its derivatives, induce anabolic programs in yeast, and drive various processes integral to metabolism (one-carbon metabolism...

journal_title：Frontiers in microbiology

authors： Walvekar AS,Laxman S

更新日期：2019-11-15 00:00:00

abstract：:Intramembrane proteases (IMPs) are a unique class of proteases that catalyze the proteolysis within the membrane and regulate diverse cellular processes in various organisms. RseP, an Escherichia coli site-2 protease (S2P) family IMP, is involved in the regulation of an extracytoplasmic stress response through the cle...

journal_title：Frontiers in microbiology

authors： Miyake T,Hizukuri Y,Akiyama Y

更新日期：2020-11-27 00:00:00

abstract：:The number of multidrug-resistant strains of Riemerella anatipestifer continues to increase, and new strategies for the treatment of associated infections are necessary. Recently, numerous studies have shown that efflux pumps (EPs) play key roles in universal bacterial mechanisms that contribute to antibiotic resistan...

journal_title：Frontiers in microbiology

authors： Chen Q,Gong X,Zheng F,Ji G,Li S,Stipkovits L,Szathmary S,Liu Y

更新日期：2018-10-01 00:00:00

abstract：:Bacteria, like all cells, must precisely duplicate their genomes before they divide. Regulation of this critical process focuses on forming a pre-replicative nucleoprotein complex, termed the orisome. Orisomes perform two essential mechanical tasks that configure the unique chromosomal replication origin, oriC to star...

journal_title：Frontiers in microbiology

authors： Leonard AC,Rao P,Kadam RP,Grimwade JE

更新日期：2019-08-29 00:00:00

abstract：:In recent years, cases of botulism in cattle and other farm animals and also in farmers increased dramatically. It was proposed, that these cases could be affiliated with the spreading of compost or other organic manures contaminated with Clostridium botulinum spores on farm land. Thus, soils and fodder plants and fin...

journal_title：Frontiers in microbiology

authors： Zeiller M,Rothballer M,Iwobi AN,Böhnel H,Gessler F,Hartmann A,Schmid M

更新日期：2015-10-31 00:00:00

abstract：:We revisited the mathematical model of the chemostat and examined consequences of considerably decreasing the concentration of limiting nutrient in the inflow for the growth of both the planktonic and biofilm cells in the chemostat tank (fermenter). The model predicts a substantially lower steady-state biomass of plan...

journal_title：Frontiers in microbiology

authors： Legner M,McMillen DR,Cvitkovitch DG

更新日期：2019-04-30 00:00:00

abstract：:Zika virus (ZIKV) infection in humans has been associated with congenital malformations and other neurological disorders, such as Guillain-Barré syndrome. The mechanism(s) of ZIKV intrauterine transmission, the cell types involved, the most vulnerable period of pregnancy for severe outcomes from infection and other ph...

journal_title：Frontiers in microbiology

authors： de Noronha L,Zanluca C,Burger M,Suzukawa AA,Azevedo M,Rebutini PZ,Novadzki IM,Tanabe LS,Presibella MM,Duarte Dos Santos CN

更新日期：2018-09-25 00:00:00

abstract：:Capsular polysaccharides (CPS), a major virulence factor in Streptococcus pneumoniae, become thicker during blood invasion while not during asymptomatic nasopharyngeal colonization. However, the underlying mechanism controlling this differential pneumococcal CPS regulation remain unclear. Here, we show how VncR, the r...

journal_title：Frontiers in microbiology

authors： Ghosh P,Shah M,Ravichandran S,Park SS,Iqbal H,Choi S,Kim KK,Rhee DK

更新日期：2019-10-01 00:00:00

abstract：:There is an urgent need for new antibiotics and alternative strategies to combat multidrug-resistant bacterial pathogens, which are a growing clinical issue. Repurposing existing approved drugs with known pharmacology and toxicology is an alternative strategy to accelerate antimicrobial research and development. In th...

journal_title：Frontiers in microbiology

authors： Thangamani S,Younis W,Seleem MN

更新日期：2015-07-28 00:00:00

abstract：:Gut microbiota (GM) modifies the intrahepatic immune microenvironment, but the underlying mechanisms remain poorly understood. Liver fibrosis-associated imprinting is predicted to be reflected in GM. This study investigated the link between GM and the intrahepatic T cell receptor (TCR) immune repertoire (IR), and whet...

journal_title：Frontiers in microbiology

authors： Liang Q,Zhang M,Hu Y,Zhang W,Zhu P,Chen Y,Xue P,Li Q,Wang K

更新日期：2020-11-27 00:00:00

abstract：:Urinary tract infection is primarily caused by Escherichia coli. Multidrug resistance and their rapid dissemination in this pathogenic microbe complicate therapeutic strategies and threaten public health. Conjugation systems responsible for interbacterial transmission of antibiotic resistance are plasmid-encoded and c...

journal_title：Frontiers in microbiology

authors： Mukherjee SK,Mukherjee M

更新日期：2019-12-18 00:00:00

abstract：:Mycobacterium tuberculosis (MTB) and non-tuberculous mycobacteria (NTM) are formidable causes of lung diseases throughout the world. While MTB is considered to be more virulent than NTM, host factors also play a key role in disease development. To elucidate whether there are differential immune responses to various my...

journal_title：Frontiers in microbiology

authors： Feng Z,Bai X,Wang T,Garcia C,Bai A,Li L,Honda JR,Nie X,Chan ED

更新日期：2020-02-07 00:00:00

abstract：:A Viable but non-culturable (VBNC) state is a bacterial survival strategy under reverse conditions. It poses a significant challenge for public health and food safety. In this study, the effect of external environmental conditions including acid, nutrition, and salt concentrations on the formation of S. aureus VBNC st...

journal_title：Frontiers in microbiology

authors： Li Y,Huang TY,Mao Y,Chen Y,Shi F,Peng R,Chen J,Yuan L,Bai C,Chen L,Wang K,Liu J

更新日期：2020-11-26 00:00:00

abstract：:Desulfotomaculum reducens strain MI-1 is a Gram-positive, sulfate-reducing bacterium also capable of reducing Fe(III). Metal reduction in Gram-positive bacteria is poorly understood. Here, we investigated Fe(III) reduction with lactate, a non-fermentable substrate, as the electron donor. Lactate consumption is concomi...

journal_title：Frontiers in microbiology

authors： Dalla Vecchia E,Shao PP,Suvorova E,Chiappe D,Hamelin R,Bernier-Latmani R

更新日期：2014-08-19 00:00:00

abstract：:The marine picocyanobacterium Synechococcus sp. WH7803 possesses two glutamine synthetases (GSs; EC 6.3.1.2), GSI encoded by glnA and GSIII encoded by glnN. This is the first work addressing the physiological regulation of both enzymes in a marine cyanobacterial strain. The increase of GS activity upon nitrogen starva...

journal_title：Frontiers in microbiology

authors： Domínguez-Martín MA,Díez J,García-Fernández JM

更新日期：2016-06-28 00:00:00

abstract：:Copper mining and the byproducts associated with the industry have led to serious pollution in the Loess Plateau of China. There is a potential in improving the ecological restoration efficiency of such degraded land through combining microbial and plant remediation approaches. However, the community structure and fun...

journal_title：Frontiers in microbiology

authors： Jia T,Yao Y,Wang R,Wu T,Chai B

更新日期：2020-05-28 00:00:00

abstract：:Highly pathogenic H5N1 avian influenza virus (A/H5N1) of clade 2.2.1 is endemic in poultry in Egypt where the highest number of human infections worldwide was reported. During the last 12 years the Egyptian A/H5N1 evolved into several genotypes. In 2007-2014 vaccinated poultry suffered from antigenic drift variants of...

journal_title：Frontiers in microbiology

authors： Salaheldin AH,Kasbohm E,El-Naggar H,Ulrich R,Scheibner D,Gischke M,Hassan MK,Arafa AA,Hassan WM,Abd El-Hamid HS,Hafez HM,Veits J,Mettenleiter TC,Abdelwhab EM

更新日期：2018-03-27 00:00:00

abstract：:The outer potato periderm layer consists of dead suberized cells. Suberin, a protective biopolymer, is made of a polyaliphatic portion covalently linked to polyaromatic moieties. Evidence accumulates that Streptomyces scabies, the main causal agent of potato common scab, can degrade the suberin aliphatic part but its ...

journal_title：Frontiers in microbiology

authors： Khalil M,Lerat S,Beaudoin N,Beaulieu C

更新日期：2019-12-04 00:00:00

abstract：:Colistin has long been a reserve drug used for the treatment of carbapenem resistant Klebsiella pneumoniae. Carbapenem resistance in K. pneumoniae has been increasing and is as high as 44% in India. Although a reserve agent, with rise in rates of resistance to carbapenems, the usage of colistin has increased over the ...

journal_title：Frontiers in microbiology

authors： Pragasam AK,Shankar C,Veeraraghavan B,Biswas I,Nabarro LE,Inbanathan FY,George B,Verghese S

更新日期：2017-01-09 00:00:00

abstract：:Carbon monoxide (CO) is a potential energy and carbon source for thermophilic bacteria in geothermal environments. Geothermal sites ranging in temperature from 45 to 65°C were investigated for the presence and activity of anaerobic CO-oxidizing bacteria. Anaerobic CO oxidation potentials were measured at up to 48.9 μm...

journal_title：Frontiers in microbiology

authors： Brady AL,Sharp CE,Grasby SE,Dunfield PF

更新日期：2015-09-01 00:00:00

abstract：:For tolerating extreme desiccation, cyanobacteria are known to produce both compatible solutes at intracellular level and a copious amount of exopolysaccharides as a protective coat. However, these molecules make cyanobacterial cells refractory to a broad spectrum of cell disruption methods, hindering genome sequencin...

journal_title：Frontiers in microbiology

authors： Urrejola C,Alcorta J,Salas L,Vásquez M,Polz MF,Vicuña R,Díez B

更新日期：2019-05-07 00:00:00

abstract：:Lower-termites are one of the best studied symbiotic systems in insects. Their ability to feed on a nitrogen-poor, wood-based diet with help from symbiotic microbes has been under investigation for almost a century. A unique microbial consortium living in the guts of lower termites is essential for wood-feeding. Host ...

journal_title：Frontiers in microbiology

authors： Peterson BF,Scharf ME

更新日期：2016-04-08 00:00:00

abstract：:Escherichia coli O157: H7 (EHEC) is a major foodborne pathogen largely transmitted to humans through the consumption of undercooked ground beef. This study investigated the efficacy of two food-grade, plant-derived antimicrobials, namely rutin (RT), and resveratrol (RV) with or without chitosan (CH) in enhancing EHEC ...

journal_title：Frontiers in microbiology

authors： Surendran Nair M,Lau P,Belskie K,Fancher S,Chen CH,Karumathil DP,Yin HB,Liu Y,Ma F,Upadhyaya I,Upadhyay A,Mancini R,Venkitanarayanan K

更新日期：2016-02-02 00:00:00

abstract：:This work aimed to characterize the mammary gland pharmacokinetics of cefquinome after an intramammary administration and integrate pharmacokinetic/pharmacodynamic model. The pharmacokinetic profiles of cefquinome in gland tissue were measured using high performance liquid chromatograph. Therapeutic regimens covered v...

journal_title：Frontiers in microbiology

authors： Yu Y,Zhou YF,Li X,Chen MR,Qiao GL,Sun J,Liao XP,Liu YH

更新日期：2016-10-07 00:00:00

abstract：:Aspergillus flavus is the main producer of carcinogenic aflatoxins in agricultural commodities such as maize. This fungus occurs naturally on crops, and produces aflatoxins when environmental conditions are favorable. The aim of this study is to analyse the genetic variability among 109 A. flavus isolates previously r...

journal_title：Frontiers in microbiology

authors： Okoth S,De Boevre M,Vidal A,Diana Di Mavungu J,Landschoot S,Kyallo M,Njuguna J,Harvey J,De Saeger S

更新日期：2018-01-26 00:00:00

abstract：:Bacterial host tropism is a primary determinant of the range of host organisms they can infect. Salmonella serotypes are differentiated into host-restricted and host-adapted specialists, and host-unrestricted generalists. In order to elucidate the underlying molecular mechanisms of host specificity in Salmonella infec...

journal_title：Frontiers in microbiology

authors： Kolenda R,Burdukiewicz M,Schiebel J,Rödiger S,Sauer L,Szabo I,Orłowska A,Weinreich J,Nitschke J,Böhm A,Gerber U,Roggenbuck D,Schierack P

更新日期：2018-08-22 00:00:00

abstract：:Soft rot caused by numerous species of Pectobacterium and Dickeya is a serious threat to the world production of potatoes. The application of bacteriophages to combat bacterial infections in medicine, agriculture, and the food industry requires the selection of comprehensively studied lytic phages and the knowledge of...

journal_title：Frontiers in microbiology

authors： Lukianova AA,Shneider MM,Evseev PV,Shpirt AM,Bugaeva EN,Kabanova AP,Obraztsova EA,Miroshnikov KK,Senchenkova SN,Shashkov AS,Toschakov SV,Knirel YA,Ignatov AN,Miroshnikov KA

更新日期：2020-01-23 00:00:00