Abstract:
:Several lines of evidence are consistent with the hypothesis that activated platelets contribute to colorectal tumorigenesis and metastatization through direct cell-cell interactions and the release of different lipid and protein mediators, and microvesicles. This review examines the clinical pharmacology of low-dose aspirin as a basis for discussing the mechanisms underlying the contribution of platelets to neoplastic transformation and progression of cancer via the development of metastases.
journal_name
Plateletsjournal_title
Plateletsauthors
Patrignani P,Patrono Cdoi
10.1080/09537104.2018.1492105subject
Has Abstractpub_date
2018-12-01 00:00:00pages
779-785issue
8eissn
0953-7104issn
1369-1635journal_volume
29pub_type
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