Reappraisal of Reported Genes for Sudden Arrhythmic Death: Evidence-Based Evaluation of Gene Validity for Brugada Syndrome.

abstract：:Amiodarone is the most effective antiarrhythmic drug for maintaining sinus rhythm for patients with atrial fibrillation. Extra-cardiac side effects have been a limiting factor, especially during chronic use, and may offset its benefits. Dronedarone is a noniodinated benzofuran derivative of amiodarone that has been de...

journal_title：Circulation

authors： Patel C,Yan GX,Kowey PR

更新日期：2009-08-18 00:00:00

abstract：:Left ventricular function was compared in 18 normal sedentary controls (mean age 28 years, range 22 - 34 years) and nine endurance-trained athletes (mean age 19 years, range 15 - 25 years) at rest and during supine bicycle exercise. Gated radionuclide angiocardiograms were performed at rest and at each level of graded...

journal_title：Circulation

authors： Bar-Shlomo BZ,Druck MN,Morch JE,Jablonsky G,Hilton JD,Feiglin DH,McLaughlin PR

更新日期：1982-03-01 00:00:00

abstract：:The effect of prolonged intense endurance exercise training on exertional hypotension was investigated in 16 patients with coronary artery disease who had a 10 mm Hg or greater fall in systolic blood pressure (SBP) during progressive exercise testing. Training consisted of walking, running, or cycling at 50% to 60% of...

journal_title：Circulation

authors： Martin WH 3rd,Ehsani AA

更新日期：1987-09-01 00:00:00

abstract：:Neutrophil activation and infiltration into the ischemic myocardium after reperfusion may limit the amount of salvageable myocardium (reperfusion injury). The effects of intravenous perfluorochemicals (Fluosol-DA) on infarct size, ventricular contractility, and neutrophil function were assessed in an occlusion-reperfu...

journal_title：Circulation

authors： Bajaj AK,Cobb MA,Virmani R,Gay JC,Light RT,Forman MB

更新日期：1989-03-01 00:00:00

abstract：BACKGROUND:Although insulin resistance has been implicated in the pathogenesis of left ventricular (LV) hypertrophy, previous studies have yielded inconsistent results and are limited by referral bias. METHODS AND RESULTS:We examined the relations between echocardiographic LV measurements and glucose tolerance status ...

journal_title：Circulation

authors： Rutter MK,Parise H,Benjamin EJ,Levy D,Larson MG,Meigs JB,Nesto RW,Wilson PW,Vasan RS

更新日期：2003-01-28 00:00:00

abstract：BACKGROUND:Left ventricular wall motion (WM) abnormalities have recognized prognostic significance in patients with coronary or other heart diseases; however, whether abnormal WM predicts adverse events in adults without overt cardiovascular disease has not been assessed. Our objective was to determine whether echocard...

journal_title：Circulation

authors： Cicala S,de Simone G,Roman MJ,Best LG,Lee ET,Wang W,Welty TK,Galloway JM,Howard BV,Devereux RB

更新日期：2007-07-10 00:00:00

abstract：BACKGROUND:Currently, only anecdotal information exists on the presentation and outcome of coronary arterial injury after ablation procedures. METHODS AND RESULTS:Four patients who sustained coronary artery injury of a cohort of patients undergoing 4655 consecutive ablation procedures (0.09%) are described. The patien...

journal_title：Circulation

authors： Roberts-Thomson KC,Steven D,Seiler J,Inada K,Koplan BA,Tedrow UB,Epstein LM,Stevenson WG

更新日期：2009-10-13 00:00:00

abstract：:Paclitaxel drug-coated balloons and drug-eluting stents became commercially available for the treatment of intermittent claudication in 2015 and 2012, respectively. Both devices demonstrated superiority in limb revascularization compared with non-paclitaxel-coated devices and were rapidly accepted into clinical practi...

journal_title：Circulation

authors： Beckman JA,White CJ

更新日期：2019-10-15 00:00:00

abstract：:Heart potentials were recorded from the entire chest surface in 42 patients suffering from Wolff-Parkinson-White syndrome. We were able to identify six types of surface maps, according to the location of the potential maximum and minimum during the delta wave. For each of these types we suggested the most likely locat...

journal_title：Circulation

authors： De Ambroggi L,Taccardi B,Macchi E

更新日期：1976-08-01 00:00:00

abstract：:Current imaging modalities can provide only a qualitative or semiquantitative measure of the severity of aortic regurgitation. Ultrafast computed tomography (CT) has the capability of rapid imaging (17 frames/sec) coupled with high spatial resolution (1.5 mm2). Eight millimeter thick images can be acquired to interrog...

journal_title：Circulation

authors： Reiter SJ,Rumberger JA,Stanford W,Marcus ML

更新日期：1987-09-01 00:00:00

abstract：BACKGROUND:DC shock catheter ablation for the treatment of ventricular tachycardia (VT) may induce VT episodes that disappear within days. METHODS AND RESULTS:A 30-J cathodal shock was delivered to the endocardial left ventricular wall in 15 closed-chest dogs. All dogs had VT during the first day after ablation. Eleve...

journal_title：Circulation

authors： Hauer RN,de Bakker JM,de Wilde AA,Straks W,Vermeulen JT,Janse MJ

更新日期：1991-07-01 00:00:00

abstract：BACKGROUND:Plaque rupture with subsequent thrombosis is recognized as the underlying pathophysiology of most acute coronary syndromes and stroke. Thus, direct thrombus visualization may be beneficial for both diagnosis and guidance of therapy. We sought to test the feasibility of direct imaging of acute and subacute th...

journal_title：Circulation

authors： Botnar RM,Perez AS,Witte S,Wiethoff AJ,Laredo J,Hamilton J,Quist W,Parsons EC Jr,Vaidya A,Kolodziej A,Barrett JA,Graham PB,Weisskoff RM,Manning WJ,Johnstone MT

更新日期：2004-04-27 00:00:00

abstract：BACKGROUND:Endothelial dysfunction of coronary arteries with impaired vasodilation has been reported in patients with arterial hypertension. However, the effect of dynamic exercise on coronary vasomotion of a stenotic vessel segment before and after PTCA has not yet been evaluated in these patients. METHODS AND RESULT...

journal_title：Circulation

authors： Frielingsdorf J,Kaufmann P,Suter T,Hug R,Hess OM

更新日期：1998-09-22 00:00:00

abstract：:The Beta-Blocker Heart Attack Trial was a multicenter, randomized, double-blind, placebo-controlled trial of propranolol therapy in 3837 men and women with acute myocardial infarction. The patients began their treatment 5-21 days after hospital admission (mean 13.8 days). During an average follow-up of 25 months, ther...

journal_title：Circulation

authors： Goldstein S

更新日期：1983-06-01 00:00:00

abstract：:Carotid artery stenting, compared with carotid endarterectomy, is emerging as an effective and less invasive method of revascularization for extracranial carotid artery stenosis. Carotid stenting is established as the treatment of choice for certain high-risk patient subsets, and ongoing clinical trials are evaluating...

journal_title：Circulation

authors： Roubin GS,Iyer S,Halkin A,Vitek J,Brennan C

更新日期：2006-04-25 00:00:00

abstract：BACKGROUND:A family history of coronary heart disease (CHD) is an independent risk factor for cardiovascular events. However, the mechanisms underlying this susceptibility have not been fully elucidated. We hypothesized that an important mediator of the familial predisposition to CHD is subclinical atherosclerosis, whi...

journal_title：Circulation

authors： Wang TJ,Nam BH,D'Agostino RB,Wolf PA,Lloyd-Jones DM,MacRae CA,Wilson PW,Polak JF,O'Donnell CJ

更新日期：2003-08-05 00:00:00

abstract：BACKGROUND:Biventricular direct cardiac compression (DCC) has the potential to support the failing heart without the complications associated with a blood/device interface encountered with the use of current ventricular assist devices. A clinically designed DCC device that provides compression pressure around the base ...

journal_title：Circulation

authors： Artrip JH,Yi GH,Levin HR,Burkhoff D,Wang J

更新日期：1999-11-09 00:00:00

abstract：BACKGROUND:To assess the long-term results of the edge-to-edge mitral repair performed without annuloplasty in degenerative mitral regurgitation (MR). METHODS AND RESULTS:From 1993 to 2002, 61 patients with degenerative MR were treated with an isolated edge-to-edge suture without any annuloplasty. Annuloplasty was omi...

journal_title：Circulation

authors： De Bonis M,Lapenna E,Maisano F,Barili F,La Canna G,Buzzatti N,Pappalardo F,Calabrese M,Nisi T,Alfieri O

更新日期：2014-09-09 00:00:00

abstract：:We evaluated high-energy phosphate (HEP) levels and the ability to perform work in rat hearts preserved by standard techniques (0.9% NaCl arrest and storage at 4 degrees C) and by continuous coronary perfusion at 22 degrees C, pH 7.25, and 55 mm Hg for 4 or 8 hr with Krebs-Henseleit buffer (KHB), modified Morgan's sol...

journal_title：Circulation

authors： Novick WM,Wallace HW,Root KL,Rozanski DJ,Fuller EO

更新日期：1986-11-01 00:00:00

abstract：:Three hundred consecutive patients who developed unstable postinfarction angina requiring isolated coronary artery bypass from 1982 through 1987 were analyzed. Hospital mortality was 5%; 15 (5.5%) additional late deaths occurred during the 69-month follow-up period (mean follow-up, 23.3 months). Significant independen...

journal_title：Circulation

authors： Gardner TJ,Stuart RS,Greene PS,Baumgartner WA

更新日期：1989-06-01 00:00:00

abstract：BACKGROUND:Fetal tachyarrhythmia may result in low cardiac output and death. Consequently, antiarrhythmic treatment is offered in most affected pregnancies. We compared 3 drugs commonly used to control supraventricular tachycardia (SVT) and atrial flutter (AF). METHODS AND RESULTS:We reviewed 159 consecutive referrals...

journal_title：Circulation

authors： Jaeggi ET,Carvalho JS,De Groot E,Api O,Clur SA,Rammeloo L,McCrindle BW,Ryan G,Manlhiot C,Blom NA

更新日期：2011-10-18 00:00:00

abstract：BACKGROUND:The antiarrhythmic drugs quinidine and verapamil are known to block alpha1-adrenoceptors (alpha1ARs). Alpha1ARs are a heterogeneous family of three subtypes (alpha1A, alpha1B, and alpha1D), and little is known about the effects of quinidine and verapamil on the different human alpha1AR subtypes. METHODS AND...

journal_title：Circulation

authors： Shibata K,Hirasawa A,Foglar R,Ogawa S,Tsujimoto G

更新日期：1998-04-07 00:00:00

abstract：BACKGROUND:The relationship of LPA single nucleotide polymorphisms (SNPs), apolipoprotein(a) isoforms, and lipoprotein(a) [Lp(a)] levels with major adverse cardiovascular events (MACE) in different ethnic groups is not well known. METHODS:LPA SNPs, apolipoprotein(a) isoforms, Lp(a), and oxidized phospholipids on apoli...

journal_title：Circulation

authors： Lee SR,Prasad A,Choi YS,Xing C,Clopton P,Witztum JL,Tsimikas S

更新日期：2017-01-17 00:00:00

abstract：BACKGROUND:Mitral leaflet extension (MLE) combined with septal myectomy is a new surgical approach to treat hypertrophic obstructive cardiomyopathy (HOCM) and an enlarged mitral leaflet area. The study presents the long-term clinical results and outcome of this technique. METHODS AND RESULTS:MLE entails grafting a glu...

journal_title：Circulation

authors： van der Lee C,Kofflard MJ,van Herwerden LA,Vletter WB,ten Cate FJ

更新日期：2003-10-28 00:00:00

abstract：BACKGROUND:Healthy levels of lifestyle factors can reduce the risk of cardiovascular disease. However, except for smoking status, often considered a traditional risk factor, their effect on cardiovascular risk prediction is unclear. METHODS AND RESULTS:We used a case-cohort design of postmenopausal nonsmokers in the m...

journal_title：Circulation

authors： Paynter NP,LaMonte MJ,Manson JE,Martin LW,Phillips LS,Ridker PM,Robinson JG,Cook NR

更新日期：2014-10-21 00:00:00

abstract：BACKGROUND:There has been considerable speculation about the role of lesion microvessels in the accumulation of leukocytes in atherosclerosis. However, direct study of microvascular recruitment of leukocytes in lesions has not been performed, and the quantitative role for this route of entry is unclear. METHODS AND RE...

journal_title：Circulation

authors： Eriksson EE

更新日期：2011-11-08 00:00:00

abstract：BACKGROUND:After repair of aortic coarctation, patients may develop restenosis, aneurysms, and pseudoaneurysms at the site of prior repair. We assessed the outcomes of late reintervention on the descending aorta after aortic coarctation repair. METHODS AND RESULTS:From March 1954 to July 2008, 130 patients had operati...

journal_title：Circulation

authors： Brown ML,Burkhart HM,Connolly HM,Dearani JA,Hagler DJ,Schaff HV

更新日期：2010-09-14 00:00:00

abstract：BACKGROUND:High-sensitivity cardiac troponin assays can help to identify patients who are at low risk of myocardial infarction in the emergency department. We aimed to determine whether the addition of clinical risk scores would improve the safety of early rule-out pathways for myocardial infarction. METHODS:In 1935 p...

journal_title：Circulation

authors： Chapman AR,Hesse K,Andrews J,Lee KK,Anand A,Shah ASV,Sandeman D,Ferry AV,Jameson J,Piya S,Stewart S,Marshall L,Strachan FE,Gray A,Newby DE,Mills NL

更新日期：2018-10-16 00:00:00

abstract：BACKGROUND:Many clinical trials use composite end points to reduce sample size, but the relative importance of each individual end point within the composite may differ between patients and researchers. METHODS AND RESULTS:We asked 785 cardiovascular patients and 164 clinical trial authors to assign 25 "spending weigh...

journal_title：Circulation

authors： Stolker JM,Spertus JA,Cohen DJ,Jones PG,Jain KK,Bamberger E,Lonergan BB,Chan PS

更新日期：2014-10-07 00:00:00

abstract：:The pulmonary function of ten adult patients with congenital pulmonary valvular stenosis was investigated. The patients clearly showed smaller lungs than healthy control subjects of equivalent age and height; lung elastic recoil pressure was normal at any given percentage of measured total lung capacity, indicating th...

journal_title：Circulation

authors： De Troyer A,Yernault JC,Englert M

更新日期：1977-10-01 00:00:00