Abstract:
AIM:To make a comparative clinical and economic assessment of a transdermal therapeutic system (TTS) for fendivia and traditional opioid analgesics in patients with malignant neoplasms (MN) during palliative care. MATERIALS AND METHODS:Pharmacoeconomic analysis of opioid analgesics used in patients with MN during analgesic therapy was made using the cost-effectiveness analysis in the framework of a budget impact analysis (BIA). RESULTS:The assessment of the medical cost structure in the fendivia and morphine groups (100 patients in each group), which was made in the framework of BIA, demonstrated that the cost of pharmacotherapy in the fendivia group was comparable with that of an ambulance call for additional analgesia and correction of the side effects of performed therapy (615,804.00 and 645,337.60 rbl. monthly, respectively). At the same time, in the morphine group the cost of an ambulance call was more than 20 times that of pharmacotherapy (2,117,514.00 and 93,120.00 rbl. monthly, respectively). Thus, the total savings from applying the fendivia TTS in the group of 100 patients ranged up to 949,492.40 rbl. monthly. CONCLUSION:The application of the fendivia TTS is clinically and pharmacoeconomically valid and leads to a considerable reduction in public health care costs.
journal_name
Ter Arkhjournal_title
Terapevticheskii arkhivauthors
Ryazhenov VV,Abuzarova GR,Gorokhova SG,Emchenko IV,Matveev NVsubject
Has Abstractpub_date
2014-01-01 00:00:00pages
63-8issue
2eissn
0040-3660issn
2309-5342journal_volume
86pub_type
杂志文章abstract:AIM:to investigate time course of changes in the adrenoreactivity (AR) of erythrocyte membranes (EM) after radiofrequency ablation of the synaptic nerves of the renal arteries (RA) in patients with resistant hypertension (RH) and to assess whether this indicator can be used for the early evaluation of the efficiency of...
journal_title:Terapevticheskii arkhiv
pub_type: 临床试验,杂志文章
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abstract::The examination was performed of 700 children with juvenile arthritis diverse in nosology. Juvenile ankylosing spondylarthritis (JSA) was diagnosed in 60 patients. In 31 of them the diagnosis was accurate, 29 patients were suspected of having JSA by Garmisch-Partenkirchen criteria. 95% of the examinees were newly diag...
journal_title:Terapevticheskii arkhiv
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abstract::Burning mouth syndrome (glossalgia) is manifested by oral pin and tingling sensations, numbness and even burning and severe pains, more frequently in the tongue. Unpleasant sensations may involve the anterior two thirds of the tongue or be extended to the front part of the hard palate and the mucous membrane of the lo...
journal_title:Terapevticheskii arkhiv
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journal_title:Terapevticheskii arkhiv
pub_type: 临床试验,杂志文章
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更新日期:2004-01-01 00:00:00
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journal_title:Terapevticheskii arkhiv
pub_type: 杂志文章,随机对照试验
doi:
更新日期:2009-01-01 00:00:00
abstract:AIM:To determine features of duodenal ulcer (DU) course as regards personality traits and to validate a differentiated approach to psychopharmacological correction of such patients. MATERIAL AND METHODS:The personality type was determined in 102 DU patients using an experimental psychological examination. RESULTS:Amo...
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doi:
更新日期:2002-01-01 00:00:00
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doi:
更新日期:1991-01-01 00:00:00
abstract::A total of 203 patients with chronic obstructive pulmonary diseases (COPD) with normal blood pressure (BP) as well as with systemic arterial hypertension of different character (labile and stable pulmonogenic essential hypertension) were examined. It was established that if COPD is associated with labile pulmonogenic ...
journal_title:Terapevticheskii arkhiv
pub_type: 杂志文章
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更新日期:1985-01-01 00:00:00
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journal_title:Terapevticheskii arkhiv
pub_type: 杂志文章
doi:
更新日期:2009-01-01 00:00:00
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pub_type: 杂志文章,评审
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journal_title:Terapevticheskii arkhiv
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更新日期:2012-01-01 00:00:00
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doi:
更新日期:2012-01-01 00:00:00
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journal_title:Terapevticheskii arkhiv
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doi:
更新日期:2009-01-01 00:00:00
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journal_title:Terapevticheskii arkhiv
pub_type: 杂志文章,多中心研究
doi:
更新日期:2001-01-01 00:00:00
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journal_title:Terapevticheskii arkhiv
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:2004-01-01 00:00:00
abstract::The reparation activity in lymphocytes using the DNA reparative synthesis test was assessed in 18 patients: 10 suffering from primary gout with renal involvement, 6 suffering from chronic nephritis with hyperuricemia, 1 with hyperuricosuria and 1 with systemic lupus erythematosus. Inhibition of the DNA reparative synt...
journal_title:Terapevticheskii arkhiv
pub_type: 杂志文章
doi:
更新日期:1986-01-01 00:00:00
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journal_title:Terapevticheskii arkhiv
pub_type: 杂志文章
doi:
更新日期:1995-01-01 00:00:00
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journal_title:Terapevticheskii arkhiv
pub_type: 杂志文章
doi:
更新日期:2010-01-01 00:00:00
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journal_title:Terapevticheskii arkhiv
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doi:
更新日期:1996-01-01 00:00:00
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doi:
更新日期:1989-01-01 00:00:00
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journal_title:Terapevticheskii arkhiv
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更新日期:2018-08-27 00:00:00
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journal_title:Terapevticheskii arkhiv
pub_type: 杂志文章,评审
doi:
更新日期:2011-01-01 00:00:00
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journal_title:Terapevticheskii arkhiv
pub_type: 杂志文章
doi:
更新日期:1995-01-01 00:00:00
abstract:AIM:To study the impact of angiotensinogen (AGT) and angiotensin II receptor type 1 (AGTR1) gene polymorphisms on the development and course of chronic heart failure (CHF) in patients with coronary heart disease (CHD). SUBJECTS AND METHODS:Two hundred and twenty-six patients (149 men and 77 women; mean age 55.9 +/- 5....
journal_title:Terapevticheskii arkhiv
pub_type: 杂志文章
doi:
更新日期:2013-01-01 00:00:00
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journal_title:Terapevticheskii arkhiv
pub_type: 杂志文章
doi:
更新日期:1998-01-01 00:00:00
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journal_title:Terapevticheskii arkhiv
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doi:
更新日期:2013-01-01 00:00:00
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journal_title:Terapevticheskii arkhiv
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:2003-01-01 00:00:00
abstract::At present, Helicobacter pylori (Нр) infection is the most common chronic bacterial infection in humans, the pathogen of which colonizes approximately 50% of the world's population. Hp eradication is required to control complications of Hp-related diseases (gastric and duodenal ulcers). Nevertheless, a number of inves...
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pub_type: 杂志文章,评审
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更新日期:2016-01-01 00:00:00