Abstract：
AIM:To study efficacy of colloid bismuth subcitrate (de-nol, Yamanuchi) in therapy of gastropathies provoked by nonsteroidal anti-inflammatory drugs (NSAID). MATERIAL AND METHODS:63 patients (38 women and 25 men, mean age 54.2 +/- 12.8 years) with rheumatoid arthritis (n = 14), osteoarthrosis (n = 47), gouty arthritis (n = 2) regularly taking NSAID were examined. The patients were randomized into two groups. The patients of the control group 1 received therapy with omeprasol (40 mg/day), patients of group 2 were given omeprasol (40 mg/day) and de-nol (480 mg/day). RESULTS:Epithelization of erosive-ulcerous lesions were observed on the treatment day 28 in 93.9% patients of group 1 and all the patients of group 2. Normalization of the level of prostaglandin E1 by the end of the treatment was registered in 57% and 93.3% patients of groups 1 and 2, respectively. CONCLUSION:Colloid bismuth subcitrate (de-nol) effectively improves the condition of NSAID gastropathy patients, stimulates healing of erosive-ulcerous lesions of gastroduodenal zone in elevation of prostaglandins levels.
journal_name
Ter Arkhjournal_title
Terapevticheskii arkhivauthors
Maev IV,V'iuchnova ES,Staseva IVsubject
Has Abstractpub_date
2004-01-01 00:00:00pages
27-30issue
2eissn
0040-3660issn
2309-5342journal_volume
76pub_type
临床试验,杂志文章,随机对照试验abstract：AIM:To evaluate efficacy of the International Prognostic Index (IPI) in relation to diffuse B-large cell lymphosarcoma (BLCLS), to identify significant prognostic factors. MATERIAL AND METHODS:The trial enrolled 121 patients (67 males and 54 females, mean age 54 years) suffering from BLCLS with involvement of the lymp...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章
doi：
更新日期：2008-01-01 00:00:00
abstract：AIM:To investigate the impact of double filtration plasmapheresis (DFPP) and therapeutic plasma exchange (TPE) on hemostasis in renal transplant recipients. MATERIALS AND METHODS:54 renal transplant patients with an acute humoral rejection were treated with therapeutic apheresis methods: 24 patients with DFPP and 30 p...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章
doi：10.26442/terarkh201890622-27
更新日期：2018-06-20 00:00:00
abstract：AIM:To characterize the genotype and genotype-phenotype correlations in patients with Gaucher disease (GD) in the Russian Federation. MATERIALS AND METHODS:One hundred adult patients with GD type 1 were examined. Their clinical study encompassed the evaluation of the severity of osteoarticular lesions from instrumenta...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章
doi：
更新日期：2013-01-01 00:00:00
abstract：AIM:To determine the effect of plasma homocysteine (Hc) on the structure and function of the left ventricle (LV) in patients treated by programmed hemodialysis. SUBJECTS AND METHODS:109 patients on programmed hemodialysis were examined. Blood Hc levels were determined and echocardiography was performed in all the pati...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章
doi：
更新日期：2013-01-01 00:00:00
abstract：:The regular character and a tendency of the time course of the absolute activity of the heart-specific blood enzymes and their coefficients in focal myocardial dystrophy, angina of effort and rest, angina of effort and unstable angina after each attack of chest pains and their recurrences which were identical to those...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章
doi：
更新日期：1987-01-01 00:00:00
abstract：AIM:To study fractional composition of red cell membrane (RCM) lipids in patients with severe iron-deficiency anemia (IDA) complicated by myocardiodystrophy prior to treatment and after 1-month combined treatment with sorbifer and mildronate. MATERIAL AND METHODS:Fatty acid composition of RCM lipids was studied in 12 ...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章
doi：
更新日期：2008-01-01 00:00:00
abstract：AIM:To study epidemiological characteristics of cryptosporidosis (CS) in conditions of arid climate which contributes to suppression of the immune status of the organism. MATERIAL AND METHODS:1935 patients were treated for acute intestinal infection with watery diarrhea in Ashkhabad hospital in 1994-1999. Monocryptosp...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章
doi：
更新日期：2002-01-01 00:00:00
abstract：:Borreliosis after sucking ticks is an acute problem in the world. People do not go to doctors after that often, which leads to the development of various complications. Thrombosis of veins of various localization can be one of them. Thrombosis of the portal vein represents a significant problem too with high morbidity...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章
doi：10.26442/terarkh2018901179-89
更新日期：2018-11-22 00:00:00
abstract：:Renal damage in HIV infection may result from direct action of HIV and from other causes including nephrotoxic action of medicines. HIV-infected patients receive a wide spectrum of medicines and can be placed in a risk group of drug-induced damage to the kidneys. Risk of nephrotoxicity should be considered in administ...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章
doi：
更新日期：2011-01-01 00:00:00
abstract：AIM:To study effects of long-term morphine-clofelin epidural analgesia and infusion of nitroglycerin on formation of the necrosis focus and the clinical course of acute myocardial infarction (MI). MATERIAL AND METHODS:Ninety patients were examined within the first 12 hours of anterior macrofocal MI. Forty six patients...
journal_title：Terapevticheskii arkhiv
pub_type： 临床试验,杂志文章
doi：
更新日期：2004-01-01 00:00:00
abstract：:Enterosorbents were tried clinically in 90 patients with chronic renal failure and in vitro (immersion into gastric juice, enteral and colon content). Advantages of granulated carbone sorbents over polyphepan, lignin derivative, were evident. ...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章
doi：
更新日期：1996-01-01 00:00:00
abstract：AIM:To identify the gender differences of cardiovascular events in patients with chronic glomerulonephritis (CGN) at the pre-dialysis stage of chronic kidney disease (CKD). SUBJECTS AND METHODS:A total of 170 patients (median age 40±11 years) with CGN who did not receive hemodialysis were examined. According to gender...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章
doi：10.17116/terarkh201789656-61
更新日期：2017-01-01 00:00:00
abstract：AIM:To assess the prevalence of bacterial overgrowth syndrome (BOS) and its risk factors in patients with inflammatory bowel diseases (IBD). SUBJECTS AND METHODS:The patients from the Novosibirsk IBD registry, who had undergone a hydrogen breath test (HBT) using a Gastro+ device, were examined. RESULTS:In 93 IBD pati...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章
doi：10.17116/terarkh201789215-19
更新日期：2017-01-01 00:00:00
abstract：:As many as 24 patients suffering from essential hypertension (EH) were examined. The patients were subjected to Holter ECG monitoring, echocardiography, coronary angiography, exercise scintigraphy of the myocardium with transesophageal pacing of the atria and the dipyridamole test. The patients manifested defects of t...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章
doi：
更新日期：1992-01-01 00:00:00
abstract：AIM:To study an association between iron metabolism, free radical oxidation (FRO), and antioxidative system (AOS) in patients with acute myeloid leukemia (AML) during intensive chemotherapy. SUBJECTS AND METHODS:AML patients (n = 14) with a median age of 46 years received 7+3 courses (n = 3) containing cytarabine > or...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章
doi：
更新日期：2013-01-01 00:00:00
abstract：AIM:To study effects of pacemaker implantation on the course of coronary heart disease (CHD) with stable angina pectoris and choice of optimal regimen of pacing. MATERIAL AND METHODS:A total of 154 CHD patients with a pacemaker were examined. All the patients had angina of effort of functional class II-IV. RESULTS:Th...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章
doi：
更新日期：2004-01-01 00:00:00
abstract：:External respiration, circulation and gas exchange trends were investigated in acute pneumonia convalescents followed up on an outpatient basis. It was found that 72% of patients admitted to hospital for acute pneumonia, upon discharge demonstrated residual clinicoroentgenological effects. Cardiorespiratory distress, ...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章
doi：
更新日期：1989-01-01 00:00:00
abstract：AIM:To study prevalence of arterial hypertension (AH) in relation to gender, age, profession, risk factors (RF), RF combination; efficacy of active long-term multifactor prevention among the employees of industrial enterprises in some regions of Russia. MATERIAL AND METHODS:14000 males and 20969 females from industria...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章,多中心研究
doi：
更新日期：2007-01-01 00:00:00
abstract：AIM:To compare a short-term hypotensive effect of intranasal ventilation with continuous positive airway pressure (CPAP-therapy) in patients with arterial hypertension stage I and placebo-control patients. MATERIAL AND METHODS:The CPAP-therapy and placebo-control groups consisted of 12 young men with arterial hyperten...
journal_title：Terapevticheskii arkhiv
pub_type： 临床试验,杂志文章
doi：
更新日期：2002-01-01 00:00:00
abstract：AIM:To study morphofunctional features of the upper airways (UAW) in wakeful patients (juveniles with arterial hypertension stage I) and genetic predisposition to UAW obstruction in sleeping patients. MATERIAL AND METHODS:The examination of 18 juveniles with arterial hypertension stage I and II normotensive juveniles ...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章
doi：
更新日期：2001-01-01 00:00:00
abstract：AIM:To study clinical and psychological features of patients with coronary heart disease (CHD) and their comparison with obesity. MATERIALS AND METHODS:The presence and intensity of cardialgia, Ketle's index, body mass fat component, tolerance to isometric load were determined in 104 patients with stable angina of eff...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章
doi：
更新日期：2000-01-01 00:00:00
abstract：:The cardiorespiratory system was studied comprehensively in 27 patients with permanent atrial fibrillation (PAF) without the clinically marked signs of circulatory failure. After allapinine treatment 15 patients with bronchial obstruction manifestations demonstrated, in the presence of lasting PAF, a significant incre...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章
doi：
更新日期：1990-01-01 00:00:00
abstract：AIM:To study dynamics of ischemic heart disease in exposure of the population of an industrial city to social-economic stress. MATERIAL AND METHODS:Official annual records of Saratov city Health Administration for 1989-1998. In public health evaluation, cardiovascular morbidity is the index rapidly reacting to social-...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章
doi：
更新日期：2005-01-01 00:00:00
abstract：:It is proposed to make a qualitative analysis of one of the most frequent bronchopulmonary symptoms--cough. This involves dynamic tussographic evaluation of the cough and expectoration in the original inulin test. The analysis covered such cough characteristics as resistance, efficacy, intensity, volleys assessed in p...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章
doi：
更新日期：1993-01-01 00:00:00
abstract：:The clinical and morphological data were studied and compared in 84 patients with Flexner's dysentery and 40 with Sonne dysentery. It is established that more pronounced and lingering colitic syndrome typical of Flexner's dysentery is related to more lasting persistence of causative agents in the superficial epitheliu...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章
doi：
更新日期：1991-01-01 00:00:00
abstract：:Echocardiographic alterations were compared with the clinical picture in 32 patients with different forms of hereditary spinocerebellar degenerations (HSCD). Three groups of patients were examined. Group I included patients with Friedreich's ataxia (FA), group II consisted of patients with familial cerebellar degenera...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章
doi：
更新日期：1990-01-01 00:00:00
abstract：AIM:To study clinical features of bronchial asthma (BA) associated with internal picture and nosogenic reactions. MATERIAL AND METHODS:Clinical features of BA were studied in 108 patients (38 males and 70 females, mean age 44.7 +/- 1.4 years, mean BA duration 6.6 +/- 0.76 years) treated in the clinic of the I. M. Sech...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章
doi：
更新日期：2001-01-01 00:00:00
abstract：:The clinical picture of chronic obstructive bronchitis (COB) coupled with lung emphysema and diffuse pulmonary fibrosis studied in 198 patients was characterized by the autonomous and emotional syndrome which depended largely on the presence and degree of arterial hypoxemia, abnormality of lung ventilation, the degree...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章
doi：
更新日期：1985-01-01 00:00:00
abstract：:Lipid peroxidation was studied by the levels of malonic dialdehyde (MDA) in the platelets and red cells of patients with diabetes mellitus (DM) type 1 as to relationships to vascular complications and insulin therapy. MDA appeared elevated both in red cells and platelets of DM patients, but was high in red cells only ...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章
doi：
更新日期：1994-01-01 00:00:00
abstract：AIM:To demonstrate great importance of intravital morphological examination of the liver for differential diagnosis of chronic diffuse diseases (CDD) of the liver. MATERIAL AND METHODS:A complete clinical examination, needle or intraoperative biopsy of the liver were made in 1045 patients with chronic diseases of the ...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章
doi：
更新日期：2011-01-01 00:00:00
