[Gender features of cardiovascular events in patients with chronic glomerulonephritis at the pre-dialysis stage of the disease].

Abstract:

AIM:To identify the gender differences of cardiovascular events in patients with chronic glomerulonephritis (CGN) at the pre-dialysis stage of chronic kidney disease (CKD). SUBJECTS AND METHODS:A total of 170 patients (median age 40±11 years) with CGN who did not receive hemodialysis were examined. According to gender, all patients were divided into 2 groups: 1) 66 female patients with CGN; 2) 104 male patients with CGN. All the patients underwent general clinical examination and transthoracic echocardiography. RESULTS:In the male group, body weight (70.2±12.3 vs 61.1±12.6 kg; p=0.000), daily proteinuria [2.286 (1.230-3.541) vs. 1.421 (0.703-2.408) g; p=0.021], aortic diameter (3.43±0.36 vs 3.15±0.32 cm; p=0.000), left atrial size (3.80±0.55 vs 3.52±0.49 cm; p=0.000), indexed left ventricular mass (LVM) (223.5±57.5 vs 205.5±54.6 g/m2, p=0.044) were significantly higher than those in the female group. Changes (atherocalcification) in the aortic valve structures were more common in the men than in the women (48% vs 22.7%; p=0.001), whereas the women were more frequently observed to have reverse blood flow along the right ventricle. CONCLUSION:In the men with CGN at the pre-dialysis stage of CKD, the increment in LVM index is associated with proteinuria and increases in right ventricle size, frequency of atherosclerotic changes in the aortic valve, and left atrial longitudinal size. :Цель исследования. Выявление половых различий сердечно-сосудистых осложнений (ССО) у пациентов с хроническим гломерулонефритом (ХГН) на додиализной стадии хронической болезни почек (ХБП). Материалы и методы. Обследовали 170 больных ХГН, не получающих гемодиализ (средний возраст 40±11 лет). В зависимости от пола все пациенты разделены на 2 группы: 1-я - 66 женщин с ХГН, 2-я - 104 мужчины с ХГН. Всем больным проводили общеклиническое обследование и трансторакальную эхокардиографию. Результаты. В группе мужчин масса тела (70,2±12,3 кг против 61,1±12,6 кг; р=0,000), суточная протеинурия [2,286 (1,230; 3,541 г против 1,421 (0,703; 2,408) г; р=0,021], диаметр аорты (3,43±0,36 см против 3,15±0,32 см; p=0,000), размер левого предсердия (3,80±0,55 см против 3,52±0,49 см; p=0,000), индексированная масса миокарда левого желудочка - ММЛЖ (223,5±57,5 г/м2 против 205,5±54,6 г/м2; р=0,044) достоверно больше, чем у женщин. У мужчин по сравнению с женщинами чаще встречались изменения (атерокальциноз) клапанных структур аорты (48% против 22,7%; р=0,001), тогда как у женщин чаще отмечался обратный поток крови по правым желудочкам. Заключение. При ХГН на додиализной стадии ХБП у лиц мужского пола прирост индекса ММЛЖ ассоциируется с протеинурией, увеличением размера правого желудочка, частоты атеросклеротических изменений аортального клапана и продольного размера левого предсердия.

journal_name

Ter Arkh

journal_title

Terapevticheskii arkhiv

authors

Murkamilov IT,Aitbaev KA,Fomin VV

doi

10.17116/terarkh201789656-61

subject

Has Abstract

pub_date

2017-01-01 00:00:00

pages

56-61

issue

6

eissn

0040-3660

issn

2309-5342

journal_volume

89

pub_type

杂志文章
  • [Electrocardiostimulation in the treatment of recurrent ventricular fibrillation in a patient with long QT syndrome on the ECG].

    abstract::Electrical stimulation of the ventricles with frequency more than spontaneous heart rate was used in a 36-year old patient suffering from rheumatic fever, paroxysms of ciliary arrhythmia to prevent recurring ventricular fibrillation in the presence of a QT elongated interval on the ECG. Medicinal therapy was provided ...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章

    doi:

    authors: Gimrikh EO,Popov SV,Pekarskiĭ VV

    更新日期:1985-01-01 00:00:00

  • [Levels of anti-inflammatory cytokines interleukin-2, interleukin-8, and soluble interleukin-2 receptor in blood of patients with various forms of ischemic heart disease].

    abstract:AIM:To quantify interleukin-8 (IL-8), interleukin-2 (IL-2) and soluble receptor of IL-2 (sIL-2r) in blood serum of patients with various forms of ischemic heart disease (IHD). MATERIAL AND METHODS:Levels of IL-8, IL-2 and sIL-2r were measured with enzyme immunoassay (EIA) in the serum of 75 patients with IHD: angina o...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章

    doi:

    authors: Mazurov VI,Stvolov SV,Linetskaia NE,Baldueva IA

    更新日期:2001-01-01 00:00:00

  • [The etiopathogenetic bases for antibacterial therapy and prevention of urinary tract infections].

    abstract::The paper discusses the pathogenesis of urinary tract infections, the mechanisms of resistance in their pathogens to antimicrobials and uroseptics, and approaches to defining patient management tactics. :В статье обсуждается патогенез инфекций мочевых путей, механизмы формирования устойчивости их возбудителей к антиб...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章,评审

    doi:10.17116/terarkh20158711123-133

    authors: Kayukov IG

    更新日期:2015-01-01 00:00:00

  • [The role of D2 vitamin metabolite paricalcitol in nephroprotective strategy in chronic disease of the kidneys].

    abstract::Calcitriol is important in nephroprotective strategy in chronic disease of the kidneys (CDK). However, its long-term use often results in hypercalciemia with metastatic calcification. Compared to calcitriol, paricalcitol (zemplar)--metabolite of vitamin D2--leads to hypercalciemia less frequently, has a more potent ne...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章,评审

    doi:

    authors: Milovanov IuS,Kozlovskaia LV,Milovanova LIu

    更新日期:2011-01-01 00:00:00

  • [Systemic manifestations of rheumatoid arthritis, echostructural changes in brachiocephalic arteries].

    abstract:AIM:To define echostructural and hemodynamic features of vascular lesions in rheumatoid arthritis (RA) with systemic manifestations. MATERIAL AND METHODS:Of 125 patients included in the study 70 had RA. They were compared to 40 patients with deforming osteoarthritis (DOA) and 15 patients with atherosclerosis of major ...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章

    doi:

    authors: Shilkina NP,Churakov OIu

    更新日期:2005-01-01 00:00:00

  • [A comparative evaluation of the efficacy of the clinical use of SKN-4M-, SKT-6A- and polifepan-type sorbents in treating patients with chronic kidney failure (clinical and experimental studies)].

    abstract::Enterosorbents were tried clinically in 90 patients with chronic renal failure and in vitro (immersion into gastric juice, enteral and colon content). Advantages of granulated carbone sorbents over polyphepan, lignin derivative, were evident. ...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章

    doi:

    authors: Ryss ES,Riabov SI,Lutoshkin MB

    更新日期:1996-01-01 00:00:00

  • [The ST-segment-dependent indices of patients with left ventricular hypertrophy and coronary failure].

    abstract::As many as 40 men suffering from essential hypertension (EH) and left ventricular hypertrophy (LVH) or hypertrophic cardiomyopathy (HCMP) were examined. All the patients exercised on a treadmill according to the Cornell protocol taking into consideration the ST/HR slope and the ST/HR index, underwent echocardiography ...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章

    doi:

    authors: Didenko VA,Iurenev AP,Anuchin VV,Dubov PB,Savchenko AP,Smirnov AA

    更新日期:1991-01-01 00:00:00

  • [Platelet-vascular and red cell components of hemostasis in hemodialyzed patients suffering from sever hemorrhagic fever with renal syndrome].

    abstract:AIM:To evaluate effect of hemodialysis on functional state of platelet-vascular and red cell components of hemostasis in patients suffering from severe hemorrhagic fever with renal syndrome (SHFRS). MATERIALS AND METHODS:Parameters of platelet-vascular and red cell hemostasis were studied in 51 patients with SHFRS who...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章

    doi:

    authors: Davidovich IM,Parshina TA

    更新日期:1999-01-01 00:00:00

  • [Chronic pancreatitis with IBS-like syndrome: approach to therapy].

    abstract:AIM:To determine approaches of the exacerbations treatment of chronic pancreatitis (CP) with IBS (irritable bowel syndrome)-like syndrome. MATERIALS AND METHODS:312 patients with exacerbation of CP were observed and received standard therapy: antispasmodics, enzymes, proton pump inhibitors. 85 (27.2%) patients had no ...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章

    doi:10.26442/00403660.2020.02.000518

    authors: Kozlova IV,Bykova AP,Osadchuk MA

    更新日期:2020-04-27 00:00:00

  • [Trisomy of chromosome 8 in Ph-negative cells of the bone marrow in patients with chronic myeloid leukemia treated with inhibitors of BCR-ABL tyrosine kinases].

    abstract:AIM:To analyse clinical implications of chromosome 8 trisomy in Ph-negative cells of the bone marrow in patients with chronic myeloid leukemia (CML) treated with inhibitors of tyrosinkinases (ITK). MATERIAL AND METHODS:A total of 386 patients with CML (chronic phase--288, acceleration phase--77) received imatinib (400...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章

    doi:

    authors: Turkina AG,Domracheva EV,Vorontsova AV,Aseeva EA,Vinogradova OIu,Stakhina OV,Gusarova GA,Diagileva OA,Semenova EA,Vakhrusheva MV,Kolosheĭnova TI,Abakumov EM,Chelysheva EIu,Goriacheva SR,Ivanova TV,Zakharova ES,Kolosova LI

    更新日期:2009-01-01 00:00:00

  • [The role of eosinophils in bronchial asthma].

    abstract::A total of 65 patients with infection-dependent bronchial asthma (BA) in the phase of exacerbation were examined for eosinophil number in the peripheral blood, forced expiration volume within the first second (FEV1), systolic pressure in the pulmonary artery (SPPA), the content of endogenous hydrocortisone and IgE, an...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章

    doi:

    authors: Marmolevskaia GS,Berestetskiĭ AB,Sergeeva LN

    更新日期:1989-01-01 00:00:00

  • [Possibility of evaluating the effectiveness of renal artery sympathetic denervation in resistant hypertension early after radiofrequency ablation].

    abstract:AIM:to investigate time course of changes in the adrenoreactivity (AR) of erythrocyte membranes (EM) after radiofrequency ablation of the synaptic nerves of the renal arteries (RA) in patients with resistant hypertension (RH) and to assess whether this indicator can be used for the early evaluation of the efficiency of...

    journal_title:Terapevticheskii arkhiv

    pub_type: 临床试验,杂志文章

    doi:10.17116/terarkh201688810-13

    authors: Rebrova TY,Ripp TM,Afanasiev SA,Mordovin VF,Muslimova EF

    更新日期:2016-01-01 00:00:00

  • [Interferon in rheumatoid arthritis].

    abstract::The paper is concerned with the role played by interferon (IF) in rheumatoid arthritis (RA). The content of IF was measured in the patients' blood serum and the possibility of the use of the preparations of exogenous interferon for the treatment of RA patients was demonstrated. Assay of serum IF in RA patients showed ...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章

    doi:

    authors: Balabanova RM,Dement'eva SP,Panasiuk AF,Mironova LL

    更新日期:1989-01-01 00:00:00

  • [Immunodiagnosis and immunotherapy of chronic nonspecific lung diseases].

    abstract::Altogether 212 patients with chronic nonspecific pulmonary diseases (CNPD) were examined. Of these, 105 patients received treatment with sodium nucleinate, 72 with levamisole, 17 with diucifon and 18 with T-activin. As compared with healthy subjects, the patients manifested significantly deviated immunological paramet...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章

    doi:

    authors: Borisova AM

    更新日期:1985-01-01 00:00:00

  • [Acarbose (glucobai) effects on lipid metabolism in patients with non-insulin dependent diabetes mellitus].

    abstract:AIM:To investigate the effect of acarbose, intestinal alpha-glucosidase inhibitor, on lipid metabolism in patients with non-insulin-dependent diabetes mellitus (NIDDM). MATERIAL AND METHODS:Glucobai was given for 6 months in a dose 300 mg/day to 63 NIDDM patients aged 40-69 years. The examination covered indices of gl...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章

    doi:

    authors: Rosliakova LV,Roĭtman AP,Ametov AS,Dolgov VV

    更新日期:2000-01-01 00:00:00

  • The impact of therapeutic plasma exchange and double filtration plasmapheresis on hemostasis in renal transplant recipients.

    abstract:AIM:To investigate the impact of double filtration plasmapheresis (DFPP) and therapeutic plasma exchange (TPE) on hemostasis in renal transplant recipients. MATERIALS AND METHODS:54 renal transplant patients with an acute humoral rejection were treated with therapeutic apheresis methods: 24 patients with DFPP and 30 p...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章

    doi:10.26442/terarkh201890622-27

    authors: Vatazin AV,Zulkarnaev AB

    更新日期:2018-06-20 00:00:00

  • [CLinico-morphologic correlations in Flexner's and Sonne dysentery].

    abstract::The clinical and morphological data were studied and compared in 84 patients with Flexner's dysentery and 40 with Sonne dysentery. It is established that more pronounced and lingering colitic syndrome typical of Flexner's dysentery is related to more lasting persistence of causative agents in the superficial epitheliu...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章

    doi:

    authors: Shuvalova EP,Polotskiĭ VIu

    更新日期:1991-01-01 00:00:00

  • [Efficacy of quadropril (spirapril) vs capropril in treatment of essential hypertension].

    abstract:AIM:To compare the efficacy of monotherapy with quadropril (spirapril) vs captopril in essential hypertension. MATERIAL AND METHODS:20 female patients aged 55 +/- 2 years with moderate hypertension (WHO classification) were included in the study. 16 patients had congestive heart failure stage II NYHA and 4 patients st...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章

    doi:

    authors: Polimbetov DS,Kraĭsman VA,Isaeva BG,Aliev FR

    更新日期:2000-01-01 00:00:00

  • [Analysis of the state-of-the-art of consulting medical care to patients with glucocorticoid-induced osteoporosis or its risk according to the data of a questionnaire survey (GLUCOST study)].

    abstract:AIM:To analyze the state-of-the-art of consulting medical care to Russian patients with glucocorticoid-induced osteoporosis (GCOP) or its risk. SUBJECTS AND METHODS:This GLUCOST study was organized and conducted by the Russian Association of Osteoporosis. A total of 1129 patients with chronic inflammatory diseases, wh...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章

    doi:10.17116/terarkh201587558-64

    authors: Baranova IA,Ershova OB,Anaev EK,Anokhina TN,Anoshenkova ОN,Batyn SZ,Belyaeva EA,Bolshakova TY,Volkorezov IA,Eliseeva LN,Kashnazarova EV,Kinyaikin MF,Kirpikova MN,Klyuchnikova EP,Korolev MA,Kuneevskaya IV,Masneva LV,Mura

    更新日期:2015-01-01 00:00:00

  • [Choice of treatment policy for hypertensive patients: its individualization, indications, and criteria].

    abstract::Fundamental innovations in the study of the regulatory mechanisms of circulation in the past 20-30 years (evidence for the role of the endothelium in local hemodynamic control, the basic significance of the tissue link of the angiotensin mechanism (A-II) of not only as a vasoconstrictor, but also a trigger of a slow p...

    journal_title:Terapevticheskii arkhiv

    pub_type: 社论

    doi:

    authors: Gogin EE

    更新日期:2010-01-01 00:00:00

  • [Reverse diffusion of hydrogen ions and its correlation with acid secretion and proliferative activity of gastric mucosal epithelium in patients with variants of chronic gastritis and peptic ulcer].

    abstract::Eighty-one patients with chronic gastritis and 124 patients with peptic ulcer were examined. It was discovered that in chronic gastritis, the concomitant gastritis included, in patients with peptic ulcer, the degree of enhancement of reverse diffusion of hydrogen ions depended on the intensity of atrophy of the fundal...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章

    doi:

    authors: Geller LI,Alekseenko SA

    更新日期:1984-01-01 00:00:00

  • [Treatment of diabetes mellitus in dialysis patients].

    abstract::Diabetes mellitus is a key cause of chronic kidney disease (CKD) in developed contries. Disorders of glucose metabolism regulation in CKD are explained by insulin resistance, decreased insulin clearance, weak hormonal response to hypoglycemia. These disturbances appear in inhibition of glomerular filtration rate under...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章,评审

    doi:

    authors: Bondar' IA,Klimontov VV

    更新日期:2011-01-01 00:00:00

  • [Brachial artery responsiveness in patients with systemic lupus erythematosus and scleroderma systematica].

    abstract:AIM:to evaluate brachial artery (BA) endothelial vasomotor function in patients with systemic lupus erythematosus (SLE) and scleroderma systematica (SDS), by using noninvasive studies. Subjects and methods. Sixty-five patients, including 25 with SLE, 20 with SDS, and 20 with atherosclerosis (AS) obliterans of lower ext...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章

    doi:

    authors: Vinogradov AA,Shilkina NP,Kostyreva NA

    更新日期:2010-01-01 00:00:00

  • [Correlations between the levels of vitamin D, parathormone, calcium, blood phosphates in patients with chronic kidney disease not treated with kidney replacement therapy].

    abstract:AIM:To characterize correlations between the levels of vitamin D, parathormone, calcium, blood phosphates in patients with different stages of chronic disease of the kidney (CDK) given no therapy replacing renal function (TRRF). MATERIAL AND METHODS:Serum levels of creatinine, electrolytes, parathormone (PTH), 25(OH)-...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章

    doi:

    authors: Smirnov AV,Volkov MM,Galkina OV,Zhloba AA,Emanuél' VL

    更新日期:2009-01-01 00:00:00

  • [The evolution of juvenile systemic scleroderma].

    abstract::60 cases of scleroderma systematica with onset in the childhood or adolescence have been analyzed. Juvenile scleroderma took, as a rule, a favourable course (78%). Slow progression was observed in 43% of patients. Stabilization occurred in 20% of cases. A complete regression was seen in 15%. The disease ran unfavorabl...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章

    doi:

    authors: Starovoĭtova MN,Guseva NG

    更新日期:1997-01-01 00:00:00

  • [Personalized medicine in clinical nephrology].

    abstract::Prospects of introduction of personification medicine principles into clinical nephrology are discussed with a special emphasis on prognosis of the course of chronic kidney diseases and response of the latter to pathogenetic therapy. ...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章

    doi:

    authors: Mukhin NA,Fomin VV

    更新日期:2012-01-01 00:00:00

  • [Hemosorption in systemic vasculitis].

    abstract::The present work summarises the experience gained with the use of extracorporeal hemoperfusion in 45 patients suffering from rheumatic diseases. During hemoperfusion, there was a decrease in the initially activated LDH, CPK, AST, ALT and AP. The reduction of the content of phospholipids and cholesterol in plasma and r...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章

    doi:

    authors: Shilkina NP,Ganin IuA,Alekseev VI,Pukhov AG

    更新日期:1989-01-01 00:00:00

  • [Antiretrovirus drugs impair kidneys in HIV-infection].

    abstract::Renal damage in HIV infection may result from direct action of HIV and from other causes including nephrotoxic action of medicines. HIV-infected patients receive a wide spectrum of medicines and can be placed in a risk group of drug-induced damage to the kidneys. Risk of nephrotoxicity should be considered in administ...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章

    doi:

    authors: Iushchuk ND,Volgina GV,Tomilina NA,Gadzhikulieva MM

    更新日期:2011-01-01 00:00:00

  • [Clinical implication of urine test for markers of endothelial dysfunction and angiogenesis factors in assessment of tubulointerstitial fibrosis in chronic glomerulonephritis].

    abstract:AIM:To evaluate contribution of endothelial dysfunction and impairment of endothelial proliferation/ regeneration to mechanisms of development of tubulointerstitial fibrosis (TIF) in chronic glomerulonephritis (CGN) basing on urinary levels of markers of endothelial activation/impairment and angiogenesis factors. MATE...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章

    doi:

    authors: Bobkova IN,Kozlovskaia LV,Rameeva AS,Varshavskiĭ VA,Golitsyna EP

    更新日期:2007-01-01 00:00:00

  • [4-component chemotherapy and radiation therapy of breast cancer].

    abstract::The treatment schedule for disseminated breast carcinoma has been developed. It includes the use of adriamycin (30 mg/m2, days 1, 8, 15), methotrexate (30 mg/m2, day 1), 5-FU (600 mg/m2, day 8), and cyclophosphamide (400 mg/m2, day 15 i. v. by jet injection). A complete response was obtained in 50 to 56% of the patien...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章

    doi:

    authors: Gritsaĭ AA,Lichinitser MR,Vyshinskaia GV,Kondrat'eva AP,Aplevich NN

    更新日期:1986-01-01 00:00:00