Abstract：
:Calcitriol is important in nephroprotective strategy in chronic disease of the kidneys (CDK). However, its long-term use often results in hypercalciemia with metastatic calcification. Compared to calcitriol, paricalcitol (zemplar)--metabolite of vitamin D2--leads to hypercalciemia less frequently, has a more potent nephroprotective effect and more rapidly decreases blood levels of parathyroid hormone. Paricalcitol in combination with lozartan has more pronounced nephroprotective effect. Morphological analysis detected inhibition of development of glomerulosclerosis and tubulointerstitial fibrosis. A cardioprotective effect of paricalcitol manifests with reduction of mortality from cardiovascular complications both at CDKpredialysis stage and in regular hemodialysis.
journal_name
Ter Arkhjournal_title
Terapevticheskii arkhivauthors
Milovanov IuS,Kozlovskaia LV,Milovanova LIusubject
Has Abstractpub_date
2011-01-01 00:00:00pages
70-3issue
6eissn
0040-3660issn
2309-5342journal_volume
83pub_type
杂志文章,评审abstract：:As many as 139 patients with dilated cardiomyopathy were examined for the effect of the clinical, ECG, x-ray, phono-, echo- and angiocardiographic indicators and heart catheterization data on the disease outcomes for 3 years after the examination. Risk factors of an unfavorable prediction were distinguished. They incl...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章
doi：
更新日期：1990-01-01 00:00:00
abstract：:Osteoarthritis is a common pathology, which indicates the great medical and social significance of this disease. The article discusses the issues of pathogenesis, risk factors and diagnosis of professional and professionally caused osteoarthritis: the age of onset of the disease, the specifics of work, the localizatio...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章
doi：10.26442/00403660.2020.06.000620
更新日期：2020-07-09 00:00:00
abstract：:Chronic thromboembolic pulmonary hypertension (CTEPH) is precapillary pulmonary hypertension, in which chronic obstruction of large and middle branches of pulmonary arteries (PAs) and secondary changes in the lung microcirculatory bed result in a progressive increase in pulmonary vascular resistance and PA pressure wi...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章,实务指引
doi：10.17116/terarkh201688990-101
更新日期：2016-01-01 00:00:00
abstract：AIM:To study left ventricular structural and functional changes in patients with chronic obstructive pulmonary disease (COPD) and chronic cor pulmonale (CCP) at different stages of a cardiac remodeling process. SUBJECTS AND METHODS:Echocardiography was used to examine 98 patients with COPD complicated by the developme...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章
doi：
更新日期：2010-01-01 00:00:00
abstract：:Monoclonal antibodies (MCA) LT1, LT2 and LT7 were characterized. It was established that MCA LT1 and LT2 (IgG1 and IgM classes, respectively) interacted with antigen 67 kD, and MCA LT7 (IgGZa)--with antigen 40 kD. MCA LT1, LT2 and LT7 were shown to identify normal and neoplastic cells of T-lymphoid type. MCA LT1 and L...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章
doi：
更新日期：1989-01-01 00:00:00
abstract：:As many as 24 patients suffering from essential hypertension (EH) were examined. The patients were subjected to Holter ECG monitoring, echocardiography, coronary angiography, exercise scintigraphy of the myocardium with transesophageal pacing of the atria and the dipyridamole test. The patients manifested defects of t...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章
doi：
更新日期：1992-01-01 00:00:00
abstract：:It is proposed to make a qualitative analysis of one of the most frequent bronchopulmonary symptoms--cough. This involves dynamic tussographic evaluation of the cough and expectoration in the original inulin test. The analysis covered such cough characteristics as resistance, efficacy, intensity, volleys assessed in p...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章
doi：
更新日期：1993-01-01 00:00:00
abstract：:The authors summed up the results of a many-year study of 13 children with Sjogren's diseases and syndrome, presented clinical characterization of patients, a course of this childhood pathology, some therapeutic problems and catamnestic data. An excerpt from a case history of a child with Sjogren's syndrome was given....
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章
doi：
更新日期：1988-01-01 00:00:00
abstract：AIM:To study whether life quality (LQ) indices may be used to evaluate the efficiency of structural resonance electromagnetic therapy (SREMT) and its correction in patients with rheumatoid arthritis (RA) and in those with osteoarthrosis (OA). SUBJECTS AND METHODS:One hundred and twenty patients with significant RA and...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章,随机对照试验
doi：
更新日期：2009-01-01 00:00:00
abstract：AIM:To evaluate alterations in the immune system (IS) in patients with different forms of secondary immunodeficiency and design of differentiated programs of reestablishment of defective functions depending on pathogenetically important type of deficiency of immunocompetent cells. MATERIALS AND METHODS:Clinicoimmunolo...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章
doi：
更新日期：2001-01-01 00:00:00
abstract：:The study demonstrated the results of the comparative analysis of various types of renal replacement therapy effects on the quality of life patients with terminal stage of chronic kidney disease on the basis of standardized questionnaires. It has been shown that the quality of life is significantly improved after a ki...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章,评审
doi：10.26442/terarkh201890689-91
更新日期：2018-06-20 00:00:00
abstract：:In the Russian Federation, the increase in all-cause and cardiovascular disease mortality began in the 1960s and lasted almost continuously until 2003. In our country, the characteristics of mortality are its substantially higher rates among men and a large regional variability, which is associated with economic, clim...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章,评审
doi：10.17116/terarkh20178915-13
更新日期：2017-01-01 00:00:00
abstract：:The examination covered 44 patients (16 males and 28 females) with chronic bronchitis (CB) associated with diseases of the nose and paranasal sinuses. Most of the patients (63.6%) had allergic rhinosinusopathy (ARSP). The kind of nasal and sinus affection varied with CB form (catarrhal or purulent). Aggravation of ENT...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章
doi：
更新日期：1996-01-01 00:00:00
abstract：AIM:To define optimal time for transplantation of bone marrow (TBM) in children with hematological malignancies. MATERIALS AND METHODS:20 allogenic TBMs were performed in children with acute myeloblastic leukemia (6 patients, 2 of them in recurrence), acute lymphoblastic leukemia (7 patients, 4 of them in recurrence),...
journal_title：Terapevticheskii arkhiv
pub_type： 临床试验,杂志文章
doi：
更新日期：1998-01-01 00:00:00
abstract：AIM:To demonstrate great importance of intravital morphological examination of the liver for differential diagnosis of chronic diffuse diseases (CDD) of the liver. MATERIAL AND METHODS:A complete clinical examination, needle or intraoperative biopsy of the liver were made in 1045 patients with chronic diseases of the ...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章
doi：
更新日期：2011-01-01 00:00:00
abstract：AIM:To examine bone mineral density in rheumatoid arthritis (RA) patients using echoosteometry (EOM), to analyze the speed of ultrasound bone conduction in patients with different variants of RA. MATERIAL AND METHODS:The study included 122 patients with verified RA diagnosis (ARA, 1987) who had not previously taken gl...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章
doi：
更新日期：2003-01-01 00:00:00
abstract：:The authors provide data obtained during echocardiographic examination of 16 patients with different patterns of alcoholic heart injury primarily at the early stages of alcoholism. The group of patients without heart rhythm abnormality showed a decrease in myocardial contractile function, moderate dilatation of the le...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章
doi：
更新日期：1985-01-01 00:00:00
abstract：:Motility disorders of the upper and lower gastrointestinal tract encompass a very wide range of structurally different diseases. Functional dyspepsia and irritable bowel syndrome (IBS) are the most common functional gastrointestinal disorders in clinical practice. In spite of the considerable prevalence of these funct...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章
doi：10.17116/terarkh2015878119-123
更新日期：2015-01-01 00:00:00
abstract：:The levels of glycemia were studied on an empty stomach, 1 and 2 h after a glucose tolerance test (75 g of glucose) in an organized population of 799 men. The character of nutrition was studied by a questionnaire method regarding all food consumed during a previous day using models of previously weighed meals and food...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章
doi：
更新日期：1988-01-01 00:00:00
abstract：AIM:To specify the risk of severe systemic manifestations and transformation into malignant lymphoma in Sjogren's disease (SD) patients with monoclonal mixed cryoglobulinemia (MMC). MATERIAL AND METHODS:A prospective study performed in 1985-1990 included 248 SD patients followed up after the initial detection of monoc...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章
doi：
更新日期：2004-01-01 00:00:00
abstract：:Investigations made by the authors permit the conclusion that in order to correct the disturbed amino acid content of the gastric mucosa and blood serum, mirroring the trends in the catabolic processes occurring in the body and disorder of liver amino acid-forming function, it is necessary to include the drugs elimina...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章
doi：
更新日期：1984-01-01 00:00:00
abstract：:It has been demonstrated that the basal gastrin level in the blood of patients with peptic ulcer of the duodenum is similar to that in normal subjects. Food stimulation raises blood gastrin in normal subjects and patients. However, in patients, the peak of the blood hormone rise is higher, with this rise lasting for a...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章
doi：
更新日期：1984-01-01 00:00:00
abstract：AIM:Epidemiological assessment of prevalence of blood hypertension (BH) in pregnant women. MATERIALS AND METHODS:Blood pressure and urinary protein were measured in 5160 gravidae observed in female consultations in 4 cities of Russia. RESULTS:BH was found in 1042(20.2%) examinees. Chronic BH was diagnosed in 306 pati...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章
doi：
更新日期：1998-01-01 00:00:00
abstract：AIM:To study efficacy of colloid bismuth subcitrate (de-nol, Yamanuchi) in therapy of gastropathies provoked by nonsteroidal anti-inflammatory drugs (NSAID). MATERIAL AND METHODS:63 patients (38 women and 25 men, mean age 54.2 +/- 12.8 years) with rheumatoid arthritis (n = 14), osteoarthrosis (n = 47), gouty arthritis...
journal_title：Terapevticheskii arkhiv
pub_type： 临床试验,杂志文章,随机对照试验
doi：
更新日期：2004-01-01 00:00:00
abstract：:Cryoglobulinemia (CG) is detected in more than 50% of patients with chronic hepatitis C (CHC); however, only 15-25% of them develop cryoglobulinemic vasculitis (CV) that is a systemic vasculitis due to the formation of immune deposits, which affects small (less than medium-sized) vessels and which is frequently fatal ...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章
doi：10.17116/terarkh2017894110-114
更新日期：2017-01-01 00:00:00
abstract：AIM:To compare cerebrovascular reactivity (CVR) in patients with rheumatoid arthritis (RA) concurrent with essential hypertension (Group 1) and in those with RA and normal blood pressure (BP) (Group 2). SUBJECTS AND METHODS:During the study of Groups 1 (n = 37) and 2 (n = 12), the investigators estimated the prevalenc...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章
doi：10.17116/terarkh201587424-29
更新日期：2015-01-01 00:00:00
abstract：AIM:To determine the effects of menopausal hormone therapy dosage on levels of proinflammatory cytokines and immunoglobulins in bodily fluids of patients with type 2 diabetes mellitus (DM) and chronic obstructive pulmonary disease (COPD) during perimenopause. MATERIALS AND METHODS:The study included 119 perimenopausal...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章
doi：10.26442/terarkh2018901079-83
更新日期：2018-11-22 00:00:00
abstract：:Ascites and hydrothorax may be the symptoms of congestive heart failure and do not always reflects presense of the decompensated liver cirrhosis. Clinical examination of patient with chronic hepatitis C which cyanosis of the lips, cervival veins pulsation, a triple heart rhythm indicated on pathology of the heart (con...
journal_title：Terapevticheskii arkhiv
pub_type：
doi：10.26442/terarkh201890874-80
更新日期：2018-08-27 00:00:00
abstract：:Sarcoidosis is a multisystem granulomatous disease of unknown etiology. Liver is frequently involved in the pathological process. Wide range of clinical manifestations can be seen: from asymptomatic lesion with normal liver function tests to cirrhosis with portal hypertension. Biopsy plays the key role in diagnosis of...
journal_title：Terapevticheskii arkhiv
pub_type： 社论
doi：10.26442/00403660.2019.04.000179
更新日期：2019-05-15 00:00:00
abstract：:The paper considers the consequences and causes of magnesium deficiency in patients with cardiovascular diseases. The features of magnesium metabolism in atherosclerosis, hypertension, and heart failure are described. Prospects of magnesium therapy in cardiology practice are discussed. ...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章,评审
doi：10.17116/terarkh20148612104-106
更新日期：2014-01-01 00:00:00
