The biology of papillomaviruses and their role in oncogenesis.

abstract：BACKGROUND:Pulmonary complications (PCs) after esophagectomy for patients with esophageal cancer have been correlated with prolonged hospital stays and in-hospital mortality. Previous studies have shown that minimally-invasive esophagectomy (MIE) is associated with a lower rate of PCs compared to conventional open surg...

journal_title：Anticancer research

authors： Kubo N,Ohira M,Yamashita Y,Sakurai K,Toyokawa T,Tanaka H,Muguruma K,Shibutani M,Yamazoe S,Kimura K,Nagahara H,Amano R,Ohtani H,Yashiro M,Maeda K,Hirakawa K

更新日期：2014-05-01 00:00:00

abstract：BACKGROUND:Docetaxel is a well tolerated chemotherapy for non-small cell lung cancer (NSCLC). However, few studies have investigated interstitial lung disease (ILD) associated with docetaxel. The purpose is to describe the incidence of this complication by using NSCLC patients. PATIENTS AND METHODS:Between September 2...

journal_title：Anticancer research

authors： Tamiya A,Naito T,Miura S,Morii S,Tsuya A,Nakamura Y,Kaira K,Murakami H,Takahashi T,Yamamoto N,Endo M

更新日期：2012-03-01 00:00:00

abstract：AIM:Heparin-binding epidermal growth factor-like growth factor (HB-EGF) is a promising target for cancer therapy. We have already started a phase I study of CRM197, a specific HB-EGF inhibitor, for advanced ovarian cancer. In this study, we evaluated possible clinical adaptations of CRM197 in combination with conventio...

journal_title：Anticancer research

authors： Tsujioka H,Fukami T,Yotsumoto F,Ueda T,Hikita S,Takahashi Y,Kondo H,Kuroki M,Miyamoto S

更新日期：2011-07-01 00:00:00

abstract：BACKGROUND:Tumorigenesis is a multistep process that begins with the abrogation of normal controls of apoptosis and cell proliferation, and the FAS receptor-ligand system is a key regulator of apoptosis. The aim of this study was to investigate whether functional polymorphisms of death pathway genes (FAS and FASL) are ...

journal_title：Anticancer research

authors： Hsu PI,Lu PJ,Wang EM,Ger LP,Lo GH,Tsay FW,Chen TA,Yang HB,Chen HC,Lin WS,Lai KH

更新日期：2008-01-01 00:00:00

abstract：:Gross cystic disease (GCD) represents an advanced form of fibrocystic disease of the breast. Bearers of macrocysts have been reported to be at risk of developing breast cancer. Natural killer (NK) cells are a lymphocyte subset deeply involved in immunosurveillance against neoplasia. We investigated whether breast cyst...

journal_title：Anticancer research

authors： Ardizzoja M,Masera RG,Tacconis P,Sartori ML,Arisio R,Massobrio M,Angeli A

更新日期：1994-03-01 00:00:00

abstract：:Mediation of cellular interactions by protein (lectin)-carbohydrate recognition presupposes the expression of respective surface determinants. Due to the importance of cellular contacts between bone marrow stromal cells, recently shown to express cell surface lectins, and tumor or normal progenitor cells for biosignal...

journal_title：Anticancer research

authors： Gabius S,Joshi SS,Gabius HJ,Sharp JG

更新日期：1991-03-01 00:00:00

abstract：:Schwannomas are benign tumors that arise from neural sheath Schwann cells. Solitary benign schwannomas are generally located in the head and neck, often along the cranial nerves, and are a particularly rare neoplasm among tumors of the retroperitoneal space. A 67-year-old man undergoing a general health check was inci...

journal_title：Anticancer research

authors： Yoshino T,Yoneda K

更新日期：2008-09-01 00:00:00

abstract：:Human papillomavirus (HPV)-positive tonsillar- and base of tongue cancer is increasing epidemically and has much better outcome than corresponding HPV-negative cancer and most other head and neck cancers with around 80% 3-year disease free survival with conventional radiotherapy and surgery. Consequently, most HPV-pos...

journal_title：Anticancer research

authors： Näsman A,Bersani C,Lindquist D,Du J,Ramqvist T,Dalianis T

更新日期：2017-10-01 00:00:00

abstract：:In pancreatic neoplasias mutations in the first exon (codon 12) of K-ras gene occur at high frequency and seem to have a diagnostic significance. We set up the DGGE conditions to search for these mutations in pancreatic tumor sample DNAs. All samples were directly classified by simply comparing their DGGE patterns wit...

journal_title：Anticancer research

authors： Pellegata NS,Losekoot M,Fodde R,Pugliese V,Saccomanno S,Renault B,Bernini LF,Ranzani GN

更新日期：1992-09-01 00:00:00

abstract：:Ras proteins must be isoprenylated at a conserved cysteine residue near the carboxyl terminus (Cys-186 in mammalian Ras p21 proteins) in order to extend their biological activity. Previous studies have indicate an intermediate in the mevalonate pathway, most likely farnesyl pyrophosphate, is the donor of this isopreny...

journal_title：Anticancer research

authors： Chen X,Hasuma T,Yano Y,Yoshimata T,Morishima Y,Wang Y,Otani S

更新日期：1997-07-01 00:00:00

abstract：:T-CAR1 is a human carcinoma cell line established from a brain metastasis. The tumour cells overexpress EGFR and contain an amplified EGFR gene. In vitro in the presence of 5% human serum the tumour cells grow as adherent cells in monolayer. Shortly after exposure to EGF a large number of tumour cells round up and det...

journal_title：Anticancer research

authors： Torp SH,Helseth E,Unsgaard G,Dalen A

更新日期：1995-05-01 00:00:00

abstract：:Induction of apoptosis by green tea polyphenols has been observed in various tumor cell systems, but whether green tea polyphenol-induced apoptosis requires caspase 3 for execution has not been confirmed. We previously reported that green tea polyphenol-induced apoptosis involved Apaf-1 accumulation and caspase 3 acti...

journal_title：Anticancer research

authors： Hsu S,Lewis J,Singh B,Schoenlein P,Osaki T,Athar M,Porter AG,Schuster G

更新日期：2003-03-01 00:00:00

abstract：BACKGROUND:Fibroblast growth factor receptors are expressed in diverse cell types. They play a critical role in tumor development. Their activation promotes cell-cycle progression, angiogenesis, and cell survival by induction/suppression of the expression of proteins involved. MATERIALS AND METHODS:Non-small cell lung...

journal_title：Anticancer research

authors： Göke A,Göke R,Ofner A,Herbst A,Lankat-Buttgereit B

更新日期：2015-11-01 00:00:00

abstract：BACKGROUND/AIM:This study aimed to investigate the bolus practice among Italian radiation oncologists. PATIENTS AND METHODS:In 2018, a survey on bolus application was sent to all members of the Italian Association of Radiotherapy and Clinical Oncology. RESULTS:The survey was joined by 102 radiation oncologists. Not a...

journal_title：Anticancer research

authors： Nuzzo M,Ursini LA,Patani F,Rosa C,Trignani M,DI Tommaso M,Meattini I,Gregucci F,Ciabattoni A,Genovesi D,Caravatta L

更新日期：2020-11-01 00:00:00

abstract：:In addition to fibronectin-derived peptides, several immunologically distinct peptides have been found to co-purify with fibronectin on gelatin-sepharose affinity chromatography of bovine plasma. We have isolated a 25kdal peptide ("25K") which co-purifies with fibronectin and which is mitogenic for cultured fibroblast...

journal_title：Anticancer research

authors： Channon KM,Ayad SR

更新日期：1986-11-01 00:00:00

abstract：BACKGROUND:Immunotherapy has become an attractive new strategy in the treatment of cancer. The laboratory and clinical study of cancer immunotherapy is rapidly advancing. However, in the clinical setting, the results of cancer immunotherapy are mixed. We therefore contend that cancer immunotherapy should be customized ...

journal_title：Anticancer research

authors： Inui T,Kuchiike D,Kubo K,Mette M,Uto Y,Hori H,Sakamoto N

更新日期：2013-07-01 00:00:00

abstract：:S-1 is a new oral formulation of 5-fluorouracil (5-FU) containing 1 M tegafur and 0.4 M 5-chloro-2,4-dihydroxypyridine (CDHP) and 1 M potassium oxonate (Oxo). It has been reported to have a high antitumor activity and low gastrointestinal toxicity in rats bearing murine and human tumors. We further studied the possibl...

journal_title：Anticancer research

authors： Kato T,Shimamoto Y,Uchida J,Ohshimo H,Abe M,Shirasaka T,Fukushima M

更新日期：2001-05-01 00:00:00

abstract：:An exponential function is proposed to describe cell growth, which incorporates the parameter signifying the population's proliferative index (f). This growth function could describe with precision the increase of peripheral blasts registered in one case of untreated CML at blast crisis, in which it revealed a pattern...

journal_title：Anticancer research

authors： Papaphilis AD

更新日期：1992-01-01 00:00:00

abstract：:Adenovirus(ADV) mediated thymidine kinase(TK) gene therapy followed by ganciclovir(GCV) administration is widely used in different types of cancer. ACV shares the same mechanism of selective cell killing in ADV/TK positive cells as GCV and can be used at 4.5 times higher doses in patients without significant side effe...

journal_title：Anticancer research

authors： Tong XW,Engehausen DG,Kaufman RH,Agoulnik I,Contant C,Freund CT,Oehler MK,Kim TE,Hasenburg A,Woo SL,Kieback DG

更新日期：1998-03-01 00:00:00

abstract：BACKGROUND/AIM:We retrospectively investigated the relationship between pathological complete response (pCR) and tumor volume (TV) reduction during neoadjuvant chemoradiation therapy (NACRT) in non-small cell lung cancer (NSCLC). PATIENTS AND METHODS:We evaluated patients who received NACRT (50 Gy/25 fractions with pl...

journal_title：Anticancer research

authors： Takahashi S,Go T,Anada M,Kinoshita T,Nishide T,Yokomise H,Shibata T

更新日期：2020-08-01 00:00:00

abstract：:We investigated whether the levels of the DNA-dependent protein kinase (DNA-PK) activity and content correlate with drug sensitivity in different tumour materials and if this can be utilised in predicting treatment outcome. DNA-PK activity and expression were investigated in tumour cells from 8 patients with chronic l...

journal_title：Anticancer research

authors： Eriksson A,Lewensoh R,Larsson R,Nilsson A

更新日期：2002-05-01 00:00:00

abstract：:Studies on taurine transport in MDR (multidrug resistant) and non-MDR KB cancer cells show that both cell types contain Na(+)- and Cl(-)-dependent high-affinity and low-affinity transport systems selective for beta-amino acids and a taurine diffusion component. Good buffers, such as HEPES or MOPS, interfered with taur...

journal_title：Anticancer research

authors： Wersinger C,Rebel G,Lelong-Rebel IH

更新日期：2001-09-01 00:00:00

abstract：BACKGROUND:Molecular mechanisms responsible for carcinogenesis in upper urinary tract urothelial carcinoma (UUTUC) are not yet clear. This study aimed to examine and correlate the subcellular localization of activin A, maspin, and the androgen receptor (AR) with demographic characteristics, pathological grade, and stag...

journal_title：Anticancer research

authors： Rau KM,Chen YJ,Sun MT,Kang HY

更新日期：2011-05-01 00:00:00

abstract：:The effects of dehydroepiandrosterone (DHEA) and 5-en-androstene-3 beta, 17 beta-diol (ADIOL) on the proliferation of MCF-7 cells were studied both in steroid - free and estradiol (E2) supplemented media. Growth was evaluated by counting the cells after six days of culture. The results show that DHEA 500 nM and ADIOL ...

journal_title：Anticancer research

authors： Boccuzzi G,Brignardello E,di Monaco M,Forte C,Leonardi L,Pizzini A

更新日期：1992-05-01 00:00:00

abstract：:This trial is based on the strategy of reversing O6-methylguanine-DNA methyltransferase (MGMT)-mediated nimustine resistance by depleting MGMT activity with streptozotocin (STZ) pretreatment. Eight patients with recurrent malignant gliomas refractory to previous nimustine chemotherapy were entered in this study. Patie...

journal_title：Anticancer research

authors： Zhao KM,Chen JM,Zuo HZ,Wu Y,Zhang YP

更新日期：1995-03-01 00:00:00

abstract：:The most widely-known anti-tumor drugs often induce marked immunosuppression which can give rise to one or more sepses. Anti-infection measures immediately applied can sometimes prove largely ineffective or even useless, the patient dying not as a result of the spread of the tumour but as a direct consequence of oppor...

journal_title：Anticancer research

authors： Castelli M,Baggio G,Ruberto AI,Malagoli M,Casolari C,Rossi T,Galatulas I

更新日期：1997-11-01 00:00:00

abstract：:We describe the case of an 80-year-old man with hepatocellular carcinoma (HCC) who developed tracheal obstruction due to peritracheal lymph node metastasis. A metastatic tumor that protruded into the airway was ablated using a neodymium yttrium-aluminium-garnet laser and then a self-expandable metallic stent (SEMS) wa...

journal_title：Anticancer research

authors： Hamai Y,Hihara J,Aoki Y,Taomoto J,Kishimoto I,Kobayashi Y,Miyata Y,Aikata H,Chayama K,Okada M

更新日期：2013-04-01 00:00:00

abstract：BACKGROUND:The heterogeneity in prostate cancer is the reason for the difficult diagnosis and prognosis of this tumor. In this study, we looked for a correlation between prostate specific antigen (PSA), tumor staging and DNA cytophotometry. MATERIALS AND METHODS:Twenty-two prostates (pT1-T4) from patients with prostat...

journal_title：Anticancer research

authors： Krause FS,Feil G,Bichler KH,Schrott KM,Akcetin ZY,Engehausen DG

更新日期：2005-05-01 00:00:00

abstract：BACKGROUND/AIM:Ninjurin1 is a 17-kDa membrane protein that is highly expressed in circulating tumor cells (CTCs) obtained from locally-advanced prostate cancer patients. As CTCs are implicated in the initiation of distant metastasis, we examined the potential contribution of Ninjurin1 to the motility of prostate cancer...

journal_title：Anticancer research

authors： Park J,Joung JY,Hwang JE,Hong D,Park WS,Lee SJ,Lee KH

更新日期：2017-04-01 00:00:00

abstract：BACKGROUND/AIM:We evaluated the clinical implications of pre- and post-treatment hematological parameters as prognostic factors in patients with locally advanced cervical cancer (LACC) who received definitive concurrent chemoradiotherapy (CCRT). PATIENTS AND METHODS:We retrospectively analyzed 125 patients with LACC (...

journal_title：Anticancer research

authors： Lee HJ,Kim JM,Chin YJ,Chong GO,Park SH,Lee YH,Hong DG,Lee YS

更新日期：2020-01-01 00:00:00