Lymph node shape in computed tomography imaging as a predictor for axillary lymph node metastasis in patients with breast cancer.

abstract：:The present study aimed to evaluate the prognostic value of venous-arterial CO2 to arterial-venous O2 (Cv-aCO2/Da-vO2) for patients with septic shock treated by fluid resuscitation. A total of 108 cases who received fluid resuscitation for septic shock at the Intensive Care Unit were retrospectively screened according...

journal_title：Experimental and therapeutic medicine

authors： Zang H,Shen X,Wang S,He Z,Cheng H

更新日期：2019-11-01 00:00:00

abstract：:The transformation of prostate cancer from an androgen-dependent state to an androgen-independent state is a lethal progression. Alterations in transcriptional programs are the basis of prostate cancer deterioration. The androgen receptor (AR), a member of the nuclear hormone receptor superfamily, mediates prostate ca...

journal_title：Experimental and therapeutic medicine

authors： Cheng Y,Yu P,Duan X,Liu C,Xu S,Chen Y,Tan Y,Qiang Y,Shen J,Tao Z

更新日期：2015-06-01 00:00:00

abstract：:The effect of hepatitis B immune globulin (HBIG) combined with hepatitis B vaccine on blocking hepatitis B virus (HBV) transmission between mother and infant and its effect on immune cells were studied. Ninety newborn infants confirmed to be HBV surface antigen (HBsAg)-positive were divided equally into three groups. ...

journal_title：Experimental and therapeutic medicine

authors： Gong J,Liu X

更新日期：2018-01-01 00:00:00

abstract：:Acute lung injury (ALI) is a common and severe disease that has been associated with significant morbidity and mortality. Understanding the epidemiology of ALI is vital for its prevention and treatment. The present study aimed to analyze the epidemiology of ALI by collecting data from patients that were submitted betw...

journal_title：Experimental and therapeutic medicine

authors： Zhou D,Qiu J,Liang Y,Dai W,Yuan D,Zhou J

更新日期：2017-03-01 00:00:00

abstract：:The present study was conducted to investigate the expression of apoptosis-related factors in peripheral blood mononuclear cells (PBMC) of patients with chronic hepatitis B and their correlation to clinical prognosis. Sixty-two patients that were diagnosed with chronic hepatitis B were admitted to Xuzhou Hospital from...

journal_title：Experimental and therapeutic medicine

authors： Guo L,Liang Y

更新日期：2017-12-01 00:00:00

abstract：:The present study examined the expression of microRNA (miRNA or miR)-204 in pulp tissues, blood and saliva from pediatric patients with pulpitis and an underlying Helicobacter pylori (Hp) infection in the stomach, and the mechanism of the associated regulation by miR-204 was assessed. A total of 26 children with pulpi...

journal_title：Experimental and therapeutic medicine

authors： Zhou S,Xu J

更新日期：2019-07-01 00:00:00

abstract：:MYH is an important enzyme in combating DNA oxidative stress in the occurrence and development of various types of tumors. To investigate the correlation between expression of the DNA repair enzyme MYH in esophageal squamous cell carcinoma and 8-oxoguanine (8-oxoG) oxidative damage, as well as the clinical significanc...

journal_title：Experimental and therapeutic medicine

authors： Shen K,Ji Y,Chen GQ,Huang B,Zhang X,Wu S,Yu GP,Wang XC

更新日期：2011-11-01 00:00:00

abstract：:Colorectal cancer has a relatively low sensitivity to paclitaxel. The purpose of this study was to investigate the role of connexin 43 (Cx43), which is a structural component of gap junctional communication (GJC), in paclitaxel cytotoxicity in colorectal cancer cells. Three colorectal cancer cell lines (HCT106, HCT116...

journal_title：Experimental and therapeutic medicine

authors： Wang S,Zhang S,Zhao Z,Zhang C,Yang X,Wang Y

更新日期：2017-08-01 00:00:00

abstract：:Cardiac fibrosis is a common phenomenon in different types of heart diseases, such as ischemic heart disease, inherited cardiomyopathy mutations, diabetes, and ageing and is associated with morbidity and mortality. Increased accumulation of extracellular matrix (ECM) that impacts cardiac function, is the underlying ca...

journal_title：Experimental and therapeutic medicine

authors： Tian J,An X,Niu L

更新日期：2017-05-01 00:00:00

abstract：:The knowledge of the expected time-to-positivity (TTP) of blood cultures by major pathogens is essential both clinically and economically. To this end, we conducted the present two-year study in our Institution, aiming to assess the TTP of all the major microorganisms including Enterobacteriaceae, Pseudomonas aerugino...

journal_title：Experimental and therapeutic medicine

authors： Moustos E,Staphylaki D,Christidou A,Spandidos DA,Neonakis IK

更新日期：2017-12-01 00:00:00

abstract：:Vascular smooth muscle cell (VSMC) accumulation and hypertrophy are common in vascular disorders, and inflammation has a crucial role in the development of these diseases. To investigate the effect of inflammation on the neurotransmission of VSMC, bioinformatic analysis was performed, following next generation sequenc...

journal_title：Experimental and therapeutic medicine

authors： Gan S,Qiu S,Feng Y,Zhang Y,Qian Q,Wan Z,Tang J

更新日期：2017-04-01 00:00:00

abstract：:Driving under the influence of alcohol and/or psychoactive substances increases the risk of severe, even fatal motor vehicle accidents. The aim of this descriptive study was to present the impact of alcohol and/or psychoactive substances on fatal road traffic accidents (RTAs) during the period 2011-2017. For this purp...

journal_title：Experimental and therapeutic medicine

authors： Papalimperi AH,Athanaselis SA,Mina AD,Papoutsis II,Spiliopoulou CA,Papadodima SA

更新日期：2019-09-01 00:00:00

abstract：:Systemic therapy in patients with concurrent psoriasis and chronic hepatitis B is a challenging task for both dermatologists and gastroenterologists since there is a high risk for hepatitis B virus (HBV) reactivation and hepatic toxicity under biological therapy. The therapeutic management of a patient with psoriasis ...

journal_title：Experimental and therapeutic medicine

authors： Raducan A,Bucur S,Caruntu C,Constantin T,Nita IE,Manolache N,Constantin MM

更新日期：2019-08-01 00:00:00

abstract：:Psoriasis affects 2-4% of the population worldwide and its treatment is currently far from satisfactory. Calcipotriol and Portulaca oleracea have been reported to exhibit the capacity to inhibit inflammation in psoriatic patients and improve their clinical condition. However, the efficacy of a combination regimen of t...

journal_title：Experimental and therapeutic medicine

authors： Zhao H,Li S,Luo F,Tan Q,Li H,Zhou W

更新日期：2015-02-01 00:00:00

abstract：:Resistance to platinum-based chemotherapy frequently poses a serious problem in the treatment of head and neck squamous cell carcinoma. In this study, we isolated cisplatin-resistant cells from a head and neck squamous cell carcinoma cell line. The mismatch repair (MMR) system is known as one of the cisplatin-resistan...

journal_title：Experimental and therapeutic medicine

authors： Adachi M,Ijichi K,Hasegawa Y,Nakamura H,Ogawa T,Kanematsu N

更新日期：2010-01-01 00:00:00

abstract：:The main function of adipocyte fatty acid-binding protein (A-FABP) is to regulate fatty acid metabolism as its molecular chaperone. The clinical significance of A-FABP in hypoxic-ischemic brain damage (HIBD) neonates is not yet clear. Free fatty acid (FFA) in cerebral cortex increases along with hypoxia ischemia degre...

journal_title：Experimental and therapeutic medicine

authors： Li M,Jiang L,Zhang H,Wang D,Zhang M,Zhang L

更新日期：2016-08-01 00:00:00

abstract：:The aim of this study is to investigate the effect of vitamin D (VD) on the learning and memory ability of fetal growth restriction (FGR) rat and the expression of NMDA receptor in hippocampus. The FGR models of rat were established through passive smoking, and divided into two groups randomly, i.e. the control group ...

journal_title：Experimental and therapeutic medicine

authors： Zong L,Chu P,Huang P,Guo Y,Lv Y

更新日期：2017-07-01 00:00:00

abstract：:MicroRNA (miR)-202 has been reported to be involved in the regulation of human cancer progression including bladder cancer, non-small cell lung cancer, pancreatic cancer and esophageal squamous cell carcinoma. However, the function of miR-202 in prostate cancer remains largely unknown. The present study demonstrated t...

journal_title：Experimental and therapeutic medicine

authors： Zhang S,Cai J,Xie W,Luo H,Yang F

更新日期：2018-08-01 00:00:00

abstract：:Endometriosis is a common reproductive disorder in women, with a global prevalence of 10-15%. Long noncoding RNAs (lncRNAs) are critical to gene transcription, cell cycle modulation and immune response. The lncRNA metastasis-associated lung adenocarcinoma transcript 1 (MALAT1) reportedly mediates autophagy of endometr...

journal_title：Experimental and therapeutic medicine

authors： Liu X,Zhang P,Li Y,Zhao N,Han H

更新日期：2021-01-01 00:00:00

abstract：:The present retrospective study aimed to investigate the prognostic factors for critically ill patients with an Acinetobacter baumannii (A. baumannii) infection. A total of 37 patients from the intensive care unit (ICU) were enrolled in the study. Data was collected from patients, including age, gender, ethnicity, A. ...

journal_title：Experimental and therapeutic medicine

authors： Xiao D,Wang L,Zhang D,Xiang D,Liu Q,Xing X

更新日期：2017-04-01 00:00:00

abstract：:Chronic inducible urticaria (CIndU) is a subgroup of chronic urticaria which can cause severe quality of life impairment by their refractory forms. The recommended treatment approach in CindU is the same as that for chronic spontaneous urticaria (CSU). However, CIndU seem to be more resistant to standard doses of H1 a...

journal_title：Experimental and therapeutic medicine

authors： Bumbăcea RS,Deaconu CG,Berghea EC

更新日期：2019-08-01 00:00:00

abstract：:Adipose stem cell-conditioned medium may promote human dermal fibroblast (HDF) proliferation and migration by activating paracrine peptides during the re-epithelization phase of wound healing. Human antimicrobial peptide LL-37 is upregulated in the skin epithelium as part of the normal response to injury. The effects ...

journal_title：Experimental and therapeutic medicine

authors： Yang EJ,Bang SI

更新日期：2017-07-01 00:00:00

abstract：:The aim of this study is to determine the accuracy rate of bronchopulmonary dysplasia (BPD) diagnosis and risk factors of short-term poor prognosis for premature infants. This study analyzed the clinical data of 81 premature infants (<32 weeks gestational age) with BPD, who were on oxygen therapy >28 days, and survive...

journal_title：Experimental and therapeutic medicine

authors： Du Z,Kong X,Ren Y,Feng Z,Huang J,Chen J,Wang R

更新日期：2017-10-01 00:00:00

abstract：:The aim of the present study was to investigate the mechanism underlying the effects of different doses of agmatine in rats with chronic epilepsy. To generate chronic epilepsy models, rats pretreated with different doses of agmatine (20, 40 and 80 mg/kg) were intraperitoneally injected with pentylenetetrazole (35 mg/k...

journal_title：Experimental and therapeutic medicine

authors： Xu H,Ou F,Wang P,Naren M,Tu D,Zheng R

更新日期：2014-07-01 00:00:00

abstract：:Oxidative stress and apoptosis serve an essential role in cisplatin-induced cardiotoxicity, which limits its clinical use, and increases the risk of cardiovascular disease. As a natural drug, the antioxidant and antitumor effects of cyanidin have been recognized, but its protective effect on cisplatin-induced cardiomy...

journal_title：Experimental and therapeutic medicine

authors： Qian P,Yan LJ,Li YQ,Yang HT,Duan HY,Wu JT,Fan XW,Wang SL

更新日期：2018-02-01 00:00:00

abstract：:Non-alcoholic fatty liver disease (NAFLD) is an inflammatory condition caused by hepatic lipid accumulation that is associated with insulin resistance, diabetes and metabolic syndrome. Although statins should be used with caution in liver diseases, they are increasingly investigated as a possible treatment for NAFLD. ...

journal_title：Experimental and therapeutic medicine

authors： Alkhatatbeh MJ,Lincz LF,Thorne RF

更新日期：2016-04-01 00:00:00

abstract：:The prognostic and predictive value of pre-treatment serum levels of carcinoembryonic antigen (CEA) and cytokeratin-19 fragments (CYFRA 21-1) were assessed in advanced non-small cell lung cancer (NSCLC) patients treated with gefitinib or erlotinib. Pre-treatment CEA and CYFRA 21-1 levels were measured in 123 advanced ...

journal_title：Experimental and therapeutic medicine

authors： Jung M,Kim SH,Lee YJ,Hong S,Kang YA,Kim SK,Chang J,Rha SY,Kim JH,Kim DJ,Cho BC

更新日期：2011-07-01 00:00:00

abstract：:Limited studies have focused on mental symptoms (anxiety and depression) and their impact on quality of life (QoL) in patients with pulmonary hypertension (PH). The objective of the present study was to assess the prevalence of anxiety and depression and their association with QoL in patients with pulmonary arterial h...

journal_title：Experimental and therapeutic medicine

authors： Zhou X,Shi H,Yang Y,Zhang Z,Zhai Z,Wang C

更新日期：2020-04-01 00:00:00

abstract：:We investigated the clinical value of fractional flow reserve (FFR) for the prognostic evaluation of patients with percutaneous coronary intervention. We enrolled 120 patients who were admitted to the hospital to undergo percutaneous coronary intervention for acute coronary syndromes between May 2014 and June 2015. Th...

journal_title：Experimental and therapeutic medicine

authors： Zhao Q,Ji Z,Li X,Di Y,An H,Wei B,Yang L,Chen W

更新日期：2018-01-01 00:00:00

abstract：:Calcineurin inhibitors (CNIs) such as cyclosporin A (CSA) and tacrolimus (FK506) are efficacious in patients with steroid-refractory or steroid-dependent ulcerative colitis (UC). We retrospectively investigated patients with refractory UC treated with CNIs to elucidate the prognostic factors for a colectomy. Data from...

journal_title：Experimental and therapeutic medicine

authors： Bamba S,Andoh A,Imaeda H,Ban H,Kobori A,Mochizuki Y,Shioya M,Nishimura T,Inatomi O,Sasaki M,Saitoh Y,Tsujikawa T,Fujiyama Y

更新日期：2012-07-01 00:00:00