Major pathogen microorganisms except yeasts can be detected from blood cultures within the first three days of incubation: A two-year study from a University Hospital.

abstract：:The present study aimed to investigate the therapeutic effects of Euterpe oleracea Mart. (EO) on alcoholic liver diseases (ALD). A total of 30 Wistar rats were randomly divided into three groups (10 rats per group), including alcohol group (alcohol intake), EO group (alcohol + EO puree intake) and control group (disti...

journal_title：Experimental and therapeutic medicine

authors： Zhou J,Zhang J,Wang C,Qu S,Zhu Y,Yang Z,Wang L

更新日期：2018-01-01 00:00:00

abstract：:The transformation of prostate cancer from an androgen-dependent state to an androgen-independent state is a lethal progression. Alterations in transcriptional programs are the basis of prostate cancer deterioration. The androgen receptor (AR), a member of the nuclear hormone receptor superfamily, mediates prostate ca...

journal_title：Experimental and therapeutic medicine

authors： Cheng Y,Yu P,Duan X,Liu C,Xu S,Chen Y,Tan Y,Qiang Y,Shen J,Tao Z

更新日期：2015-06-01 00:00:00

abstract：:Epilepsy is one of the few neurologic disorders that requires a constant treatment during pregnancy. Epilepsy affects 0.3-0.8% of pregnant women. Prescription of antiepileptic drugs (AEDs) to pregnant women with epilepsy requires monitoring and maintaining a balance between limiting seizures and decreasing fetal expos...

journal_title：Experimental and therapeutic medicine

authors： Nie Q,Su B,Wei J

更新日期：2016-10-01 00:00:00

abstract：:Pancreatic cancer is one of the most lethal types of cancer, and curative resection is only applicable to potentially limited cases due to early metastasis and local invasion. This study reports the influence of CXCL12 and its receptor CXCR4 on the progression of pancreatic cancer and highlights the correlation betwee...

journal_title：Experimental and therapeutic medicine

authors： Zhong W,Chen W,Zhang D,Sun J,Li Y,Zhang J,Gao Y,Zhou W,Li S

更新日期：2012-09-01 00:00:00

abstract：:The aim of the present study was to evaluate the predictive efficiency of mean platelet volume (MPV) and platelet size deviation width (PDW) for bone marrow failure (BMF) in thrombocytopenic patients. Platelet count, MPV and PDW data were retrieved from the records of 574 unselected thrombocytopenic patients from betw...

journal_title：Experimental and therapeutic medicine

authors： Xu RL,Zheng ZJ,Ma YJ,Hu YP,Zhuang SH

更新日期：2013-01-01 00:00:00

abstract：:The present study aimed to investigate the role of plasminogen activator inhibitor-1 (PAI-1) in drug-induced early cognitive impairment and the underlying mechanism concerning microRNA (miR)-30b. A mouse model of cognitive impairment was established by intraperitoneal injection of scopolamine (2 mg/kg body weight) for...

journal_title：Experimental and therapeutic medicine

authors： Li X,Gao Y,Meng Z,Zhang C,Qi Q

更新日期：2016-05-01 00:00:00

abstract：:Schwannomas are benign encapsulated tumors arising from Schwann cells in the peripheral nervous system. Between 25 and 45% of schwannomas occur in the head and neck region. Schwannomas of the larynx are extremely rare with an incidence of 0.1-1.5% in all benign laryngeal tumors. Laryngeal schwannomas usually occur in ...

journal_title：Experimental and therapeutic medicine

authors： Wang B,Dong P,Shen B,Xu H,Zheng J

更新日期：2014-04-01 00:00:00

abstract：:The present study aimed to investigate the role and mechanism of microRNA-539 (miR-539) in rheumatoid arthritis (RA). A total of 68 RA patients and 46 osteoarthritis patients were enrolled into the current study. Peripheral blood and joint fluid were collected prior to treatment. Reverse transcription-quantitative pol...

journal_title：Experimental and therapeutic medicine

authors： Liu Y,Qian K,Li C,Ma Y,Chen X

更新日期：2018-03-01 00:00:00

abstract：:Mesenchymal stem cells (MSCs) are involved in bone formation in the embryo, bone repair and remodeling. The differentiation of these cells is a complex multistep pathway that involves discrete cellular transitions and is similar to that which occurs during hematopoiesis. MSCs have self-renewal capacity without differe...

journal_title：Experimental and therapeutic medicine

authors： Shima WN,Ali AM,Subramani T,Mohamed Alitheen NB,Hamid M,Samsudin AR,Yeap SK

更新日期：2015-06-01 00:00:00

abstract：:Although there has been progress moving from a 'one-size-fits-all' cytotoxic approach to personalized molecular medicine, the majority of patients with cancer receive chemotherapy using cytotoxic anticancer drugs. The sequencing analysis of 409 genes associated with cancer was conducted in the present study using 59 D...

journal_title：Experimental and therapeutic medicine

authors： Udagawa C,Sasaki Y,Suemizu H,Ohnishi Y,Ohnishi H,Tokino T,Zembutsu H

更新日期：2018-02-01 00:00:00

abstract：:The present study aimed to evaluate the clinical efficacy of hyperbaric oxygen (HBO) treatment for depression in the convalescent stage following cerebral hemorrhage. A total of 60 cases of patients with depression in the convalescent stage following cerebral hemorrhage (2-6 months) were randomly divided into the trea...

journal_title：Experimental and therapeutic medicine

authors： Cao H,Ju K,Zhong L,Meng T

更新日期：2013-06-01 00:00:00

abstract：:microRNA (miRNA) expression profiles of gastric cancer (GC) and adjacent healthy gastric mucosa tissue were used to search for differentially expressed miRNAs, identifying downregulated miRNA-490-3p in GC. The present study aimed to investigate the cellular function of miRNA-490-3p and its underlying mechanism in the ...

journal_title：Experimental and therapeutic medicine

authors： Yu H,Sun J,Jiang S,Xu Y

更新日期：2019-02-01 00:00:00

abstract：:Matrix metalloproteases (MMPs) are a family of zinc-dependent endopeptidases that degrade extracellular matrix proteins. MMP-1 and MMP-2 are produced by endothelial cells and are involved in specific vascular pathologies, including atherosclerosis and aortal aneurysm. One of the most important differences between thes...

journal_title：Experimental and therapeutic medicine

authors： Siemianowicz K,Gminski J,Goss M,Francuz T,Likus W,Jurczak T,Garczorz W

更新日期：2010-11-01 00:00:00

abstract：:An increasing number of cancer patients receive outpatient chemotherapy as an alternative to inpatient chemotherapy. The aim of this study was to investigate whether quality of life (QOL) during outpatient chemotherapy was better than QOL prior to hospital discharge, and to explore possible related factors prior to ho...

journal_title：Experimental and therapeutic medicine

authors： Matsuda A,Kobayashi M,Sakakibara Y,Tamaoka M,Furuiye M,Inase N,Matsushima E

更新日期：2011-03-01 00:00:00

abstract：:Anti-mitochondrial M2 antibody (AMA-M2) is specific to primary biliary cirrhosis (PBC), but can also be found in certain patients with autoimmune hepatitis (AIH). Effective methods of differentiating between PBC and AIH are required, as their clinical course and management are different. Titers of AMA-M2 were analyzed...

journal_title：Experimental and therapeutic medicine

authors： Tomizawa M,Shinozaki F,Fugo K,Motoyoshi Y,Sugiyama T,Yamamoto S,Kishimoto T,Ishige N

更新日期：2015-10-01 00:00:00

abstract：:Numerous studies have demonstrated that neuronal cell death occurs via extrinsic (death receptors) and intrinsic (mitochondria) pathways. Radiation induces caspase activation fundamentally via the mitochondrial pathway. To investigate the role of caspase, a cell permeable pan-caspase inhibitor, z-VAD-fmk [N-benzyloxyc...

journal_title：Experimental and therapeutic medicine

authors： Li J,Wang Y,DU L,Xu C,Cao J,Wang Q,Liu Q,Fan F

更新日期：2014-02-01 00:00:00

abstract：:The oxidation of tyrosine to 3-nitrotyrosine is irreversible, and due to this characteristic, 3-nitrotyrosine is used as a marker for oxidative stress in a range of diverse chronic and degenerative diseases. It has been established that the yeast Debaryomyces hansenii (D. hansenii) can assimilate free 3-nitrotyrosine ...

journal_title：Experimental and therapeutic medicine

authors： Calderón-Torres CM,Sarabia-Curz L,Ledesma-Soto Y,Murguía-Romero M,Terrazas LI

更新日期：2019-05-01 00:00:00

abstract：:Eukaryotic translation initiation factor (EIF) 5A2 exerts important functions that regulate the development and progression of cancers. The present study aimed to investigate the expression of EIF5A2 in prostate cancer (PCa) and its association with biological and prognostic significance. EIF5A2 mRNA and protein level...

journal_title：Experimental and therapeutic medicine

authors： Lu J,Zhao HW,Chen Y,Wei JH,Chen ZH,Feng ZH,Huang Y,Chen W,Luo JH,Fang Y

更新日期：2019-05-01 00:00:00

abstract：:Mitochondrial factor and cell cytokines play important roles in the incidence of vascular dementia (VD), but their correlations with inflammatory and mitochondrial factors and the role of both in the kidney essence deficiency pattern and phlegm turbidity blocking orifice pattern are not clear. This study was aimed at ...

journal_title：Experimental and therapeutic medicine

authors： Sun L

更新日期：2018-01-01 00:00:00

abstract：:Extramedullary hematopoiesis (EMH) is defined as hematopoiesis occurring in organs outside of the bone marrow. The present report describes two cases of thalassemic patients with paraspinal medullary hematopoiesis and analyzes the clinical manifestations, imaging, pathology, diagnosis and treatment of EMH. In addition...

journal_title：Experimental and therapeutic medicine

authors： Zhang HZ,Li Y,Liu X,Chen BR,Yao GH,Peng YN

更新日期：2016-12-01 00:00:00

abstract：:A major consequence of obstructive jaundice (OJ) in clinical practice is the development of severe liver injury, and at present, no effective treatments have been developed to protect against it. Preconditioning with damage-associated molecular pattern (DAMP) molecules has been demonstrated to protect multiple organs ...

journal_title：Experimental and therapeutic medicine

authors： Zhou YX,Ni Y,Liu YB,Liu X

更新日期：2014-07-01 00:00:00

abstract：:Hepatocellular carcinoma (HCC) is one of the most common malignant types of cancer, with a high mortality rate. Sorafenib is the sole approved oral clinical therapy against advanced HCC. However, individual patients exhibit varying responses to sorafenib and the development of sorafenib resistance has been a new chall...

journal_title：Experimental and therapeutic medicine

authors： Huang D,Yuan W,Li H,Li S,Chen Z,Yang H

更新日期：2018-09-01 00:00:00

abstract：:The present study assessed the effects of γ-aminobutyric acid (GABA) from β-cells on glucose levels and glucagon secretion, and identified channels via which glucagon secretion is initiated. An in vivo experiment was performed containing three groups: Intrapancreatic artery infusion of GABA alone, GABA plus insulin or...

journal_title：Experimental and therapeutic medicine

authors： Yu T,Jiang Z,Liu L,Fan Z

更新日期：2018-03-01 00:00:00

abstract：:The current study assessed the association between toll-like receptor 9 (TLR9) and systemic lupus erythematosus (SLE) and subsequently determined the predictive value of TLR9 in assessing the prognosis of SLE. A total of 90 newly diagnosed patients with SLE and 49 healthy control subjects were enrolled in the current ...

journal_title：Experimental and therapeutic medicine

authors： Yuan Y,Zhao L,Ye Z,Ma H,Wang X,Jiang Z

更新日期：2019-04-01 00:00:00

abstract：:The main function of adipocyte fatty acid-binding protein (A-FABP) is to regulate fatty acid metabolism as its molecular chaperone. The clinical significance of A-FABP in hypoxic-ischemic brain damage (HIBD) neonates is not yet clear. Free fatty acid (FFA) in cerebral cortex increases along with hypoxia ischemia degre...

journal_title：Experimental and therapeutic medicine

authors： Li M,Jiang L,Zhang H,Wang D,Zhang M,Zhang L

更新日期：2016-08-01 00:00:00

abstract：:Pulmonary mucormycosis, a relatively rare pulmonary fungal disease, is difficult to diagnose and lacks effective treatment. The present study reports the case of a 64-year-old patient who was treated successfully for pulmonary mucormycosis in Xuan Wu Hospital. The patient presented with low-grade fever and a productiv...

journal_title：Experimental and therapeutic medicine

authors： Luo Z,Zhang L

更新日期：2017-10-01 00:00:00

abstract：:Giant aneurysm of the posterior circulation is associated with a higher risk of rupture compared with that of the anterior circulation. Furthermore, surgical clipping and interventional embolization for giant aneurysm of the posterior circulation are more difficult and complex to perform. The present study reported on...

journal_title：Experimental and therapeutic medicine

authors： Zhang CL,Shi ZH,Yan ZZ,Ding CL,Cao JM,Wang YH,Zhang P

更新日期：2021-01-01 00:00:00

abstract：:Cardiac inhibition due to burn injury and anesthetics have been documented previously. However, little is known about their combined effects on cardiac function. The aim of the present study was to observe the effects of a ketamine/xylazine (K/X) combination on the cardiac function of rats with severe scalds and compa...

journal_title：Experimental and therapeutic medicine

authors： Feng Y,Chai J,Chu W,Ma L,Zhang P,Duan H

更新日期：2013-09-01 00:00:00

abstract：:Previous research has shown that breathing exercises may improve the prognosis and health status in patients with lung cancer by enhancing pulmonary function and quality of life (QOL). However, individually published results are inconclusive. The aim of the present meta-analysis was to evaluate the clinical value of b...

journal_title：Experimental and therapeutic medicine

authors： Liu W,Pan YL,Gao CX,Shang Z,Ning LJ,Liu X

更新日期：2013-04-01 00:00:00

abstract：:The presence of an occluded culprit artery or collaterals in non-ST-segment elevation myocardial infarction (NSTEMI) is relatively common; however, limited data are available regarding their clinical significance. The aim of the current study was to determine the clinical characteristics of occluded culprit arteries a...

journal_title：Experimental and therapeutic medicine

authors： Hwang HJ,Park CB,Cho JM,Jin ES,Sohn IS,Kim DH,Kim CJ

更新日期：2018-10-01 00:00:00